Heat-aggregated noninfectious influenza virus induces a more balanced CD8+-T-lymphocyte immunodominance hierarchy than infectious virus

Journal of Virology

Volumn 77, Issue 8, 2003, Pages 4679-4684

  Cho, Yunjung ^a,c   Basta, Sameh ^a   Chen, Weisan ^a   Bennink, Jack R ^a   Yewdell, Jonathan W ^a,b  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c Korea University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTICLE; CELLULAR IMMUNITY; CYTOKINE PRODUCTION; ENDOSOME; FEMALE; IN VITRO STUDY; INCUBATION TIME; INFLUENZA; INFLUENZA VIRUS; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PERITONEAL EXUDATE CELL; PHAGOCYTOSIS; PRIORITY JOURNAL; T LYMPHOCYTE; TEMPERATURE;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, VIRAL; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; DENDRITIC CELLS; HEAT; HUMANS; IMMUNODOMINANT EPITOPES; INFLUENZA A VIRUS; INFLUENZA VACCINES; INFLUENZA, HUMAN; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; SPLEEN; TUMOR CELLS, CULTURED;

EID: 0037384655     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.77.8.4679-4684.2003     Document Type: Article

References (40)

1. + T cell response to influenza A viruses. J. Immunol. 165:2404-2409.
2. + T-cell response is much less apparent following secondary challenge. J. Virol. 74:3486-3493.
3. + T cell responses. J. Immunol. 166:4627-4633.
4. Bevan, M. J. 1976. Minor H antigens introduced on H-2 different stimulating cells cross-react at the cytotoxic T cell level during in vivo priming. J. Immunol. 117:2233-2238.
5. Chefalo, P. J., and C. V. Harding. 2001. Processing of exogenous antigens for presentation by class I MHC molecules involves post-Golgi peptide exchange influenced by peptide-MHC complex stability and acidic pH. J. Immunol. 167:1274-1282.
6. Chen, W., L. C. Anton, J. R. Bennink, and J. W. Yewdell. 2000. Dissecting the multifactorial causes of immunodominance in class I-restricted T cell responses to viruses. Immunity 12:83-93.
7. + T cells at the levels of T cell repertoire and presentation of viral antigens. J. Exp. Med. 193:1319-1326.
8. Chen, W., J. W. Yewdell, R. L. Levine, and J. R. Bennink. 1999. Modification of cysteine residues in vitro and in vivo affects the immunogenicity and antigenicity of major histocompatibility complex class I-restricted viral determinants. J. Exp. Med. 189:1757-1764.
9. + memory T cells specific for a subdominant epitope following Sendai virus infection. J. Immunol. 158:4301-4309.
10. Day, P. M., F. Esquivel, J. Lukszo, J. R. Bennink, and J. W. Yewdell. 1995. Effect of TAP on the generation and intracellular trafficking of peptide-receptive major histocompatibility complex class I molecules. Immunity 2:137-147.
11. Deng, Y., J. W. Yewdell, L. C. Eisenlohr, and J. R. Bennink. 1997. MHC affinity, peptide liberation, T cell repertoire, and immunodominance all contribute to the paucity of MHC class I-restricted peptides recognized by antiviral CTL. J. Immunol. 158:1507-1515.
12. + T cells: cross-priming in infectious diseases. Curr. Opin. Immunol. 13:437-441.
13. Esquivel, F., J. W. Yewdell, and J. R. Bennink. 1992. RMA/S cells present endogenously synthesized cytosolic proteins to class I-restricted cytotoxic T lymphocytes. J. Exp. Med. 175:163-168.
14. Falk, K., O. Rötzschke, K. Deres, J. Metzger, G. Jung, and H.-G. Rammensee. 1991. Identification of naturally processed viral nonapeptides allows their quantification in infected cells and suggests an allele-specific T cell epitope forecast. J. Exp. Med. 174:425-434.
15. Moore, M. W., F. R. Carbone, and M. J. Bevan. 1988. Introduction of soluble protein into the class I pathway of antigen processing and presentation. Cell 54:777-785.
16. Norbury, C. C., B. J. Chambers, A. R. Prescott, H. G. Ljunggren, and C. Watts. 1997. Constitutive macropinocytosis allows TAP-dependent major histocompatibility complex class I presentation of exogenous soluble antigen by bone marrow-derived dendritic cells. Eur. J. Immunol. 27:280-288.
17. Norbury, C. C., L. J. Hewlett, A. R. Prescott, N. Shastri, and C. Watts. 1995. Class I MHC presentation of exogenous soluble antigen via macropinocytosis in bone marrow macrophages. Immunity 3:783-791.
18. Ochsenbein, A. F., S. Sierro, B. Odermatt, M. Pericin, U. Karrer, J. Hermans, S. Hemmi, H. Hengartner, and R. M. Zinkernagel. 2001. Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction. Nature 411:1058-1064.
19. b cells. J. Immunol. 152:4843-4851.
20. Porgador, A., J. W. Yewdell, Y. Deng, J. R. Bennink, and R. N. Germain. 1997. Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody. Immunity 6:715-726.
21. Ramachandra, L., E. Noss, W. H. Boom, and C. V. Harding. 1999. Phagocytic processing of antigens for presentation by class II major histocompatibility complex molecules. Cell. Microbiol. 1:205-214.
22. Reimann, J., and R. Schirmbeck. 1999. Alternative pathways for processing exogenous and endogenous antigens that can generate peptides for MHC class I-restricted presentation. Immunol. Rev. 172:131-152.
23. Rodriguez, A., A. Regnault, M. Kleijmeer, P. Ricciardi-Castagnoli, and S. Amigorena. 1999. Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells. Nat. Cell Biol. 1:362-368.
24. d-restricted epitope presentation depends on exogenous β2-microglobulin. Eur. J. Immunol. 27:3471-3484.
25. Schirmbeck, R., J. Wild, and J. Reimann. 1998. Similar as well as distinct MHC class I-binding peptides are generated by exogenous and endogenous processing of hepatitis B virus surface antigen. Eur. J. Immunol. 28:4149-4161.
26. Shen, Z., G. Reznikoff, G. Dranoff, and K. L. Rock. 1997. Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules. J. Immunol. 158:2723-2730.
27. Sherman, L. A., T. A. Burke, and J. A. Biggs. 1992. Extracellular processing of antigens that bind class I major histocompatibility molecules. J. Exp. Med. 175:1221-1226.
28. 2-microglobulin in the processing of bacterial or particulate antigens via an alternate class I MHC processing pathway. J. Immunol. 156:4182-4190.
29. Song, R., A. Porgador, and C. V. Harding. 1999. Peptide-receptive class I major histocompatibility complex molecules on TAP-deficient and wild-type cells and their roles in the processing of exogenous antigens. Immunology 97:316-324.
30. Speidel, K., W. Osen, S. Faath, I. Hilgert, R. Obst, J. Braspenning, F. Momburg, G. J. Hammerling, and H. G. Rammensee. 1997. Priming of cytotoxic T lymphocytes by five heat-aggregated antigens in vivo: conditions, efficiency, and relation to antibody responses. Eur. J. Immunol. 27:2391-2399.
31. Srivastava, P. K., A. Menoret, S. Basu, R. J. Binder, and K. L. McQuade. 1998. Heat shock proteins come of age: primitive functions acquire new roles in an adaptive world. Immunity 8:657-665.
32. Townsend, A., C. Öhlen, J. Bastin, H.-G. Ljunggren, L. Foster, and K. Kärre. 1989. Association of class I major histocompatibility heavy and light chains induced by viral peptides. Nature 340:443-448.
33. Townsend, A. R. M., J. Rothbard, F. M. Gotch, G. Bahadur, D. Wraith, and A. J. McMichael. 1986. The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides. Cell 44:959-968.
34. 2-microglobulin in peptide binding by class I molecules. Science 250:1423-1426.
35. b-restricted epitopes. J. Immunol. 157:5555-5562.
36. Wick, M. J., and H. G. Ljunggren. 1999. Processing of bacterial antigens for peptide presentation on MHC class I molecules. Immunol. Rev. 172:153-162.
37. Yewdell, J., L. C. Anton, I. Bacik, U. Schubert, H. L. Snyder, and J. R. Bennink. 1999. Generating MHC class I ligands from viral gene products. Immunol. Rev. 172:97-108.
38. Yewdell, J. W., and J. R. Bennink. 1999. Immunodominance in major histocompatibility complex class I-restricted T lymphocyte responses. Annu. Rev. Immunol. 17:51-88.
39. Yewdell, J. W., J. R. Bennink, and Y. Hosaka. 1988. Cells process exogenous proteins for recognition by cytotoxic T lymphocytes. Science 239:637-640.
40. + T cell responses to infectious agents, tumors, transplants, and vaccines. Adv. Immunol. 73:1-77.