Drug sequestration in cytoplasmic organelles does not contribute to the diminished sensitivity of anthracyclines in multidrug resistant K562 cells

European Journal of Biochemistry

Volumn 268, Issue 16, 2001, Pages 4459-4467

  Loetchutinat, Chatchanok ^a   Priebe, Waldemar ^b   Garnier Suillerot, Arlette ^a  

^a UNIVERSITÉ PARIS 13   (France)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

Anthracycline; Daunorubicin; Intravesicular accumulation; Multidrug resistance

Indexed keywords

AMINE; ANTHRACYCLINE DERIVATIVE; DAUNORUBICIN; DAUNORUBICIN DERIVATIVE; HYDROXYRUBICIN; IDARUBICIN; UNCLASSIFIED DRUG; WP 900;

ARTICLE; BINDING AFFINITY; CELL ORGANELLE; CELL STRAIN K 562; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA BINDING; DRUG ACCUMULATION; DRUG DISTRIBUTION; DRUG SENSITIVITY; DRUG STRUCTURE; ENANTIOMER; FLOW CYTOMETRY; FLUORESCENCE; HUMAN; HUMAN CELL; LIPOPHILICITY; LYSOSOME; MULTIDRUG RESISTANCE; PH; PRIORITY JOURNAL; REGULATORY MECHANISM; TUMOR CELL LINE;

ANTIBIOTICS, ANTINEOPLASTIC; CELL NUCLEUS; CYTOPLASM; DNA; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; HUMANS; HYDROGEN-ION CONCENTRATION; K562 CELLS;

EID: 0034832401     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2001.02370.x     Document Type: Article

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