메뉴 건너뛰기




Volumn 97, Issue 3, 2005, Pages 312-316

Mitochondrial dysfunction, endoplasmic reticulum stress, and apoptosis in Alzheimer's disease

Author keywords

Alzheimer's disease; Amyloid peptide; Apoptosis; Endoplasmic reticulum stress; Mitochondrial dysfunction

Indexed keywords

AMYLOID BETA PROTEIN; PRESENILIN 1; PRESENILIN 2;

EID: 17144425021     PISSN: 13478613     EISSN: None     Source Type: Journal    
DOI: 10.1254/jphs.CPJ04006X     Document Type: Review
Times cited : (125)

References (30)
  • 1
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer's disease: Genes, proteins, and therapy
    • Selkoe DJ. Alzheimer's disease: genes, proteins, and therapy. Physiol Rev. 2001;81:741-766.
    • (2001) Physiol Rev , vol.81 , pp. 741-766
    • Selkoe, D.J.1
  • 2
    • 3943092621 scopus 로고    scopus 로고
    • Pathways towards and away from Alzheimer's disease
    • Mattson MP. Pathways towards and away from Alzheimer's disease. Nature. 2004;430:631-639.
    • (2004) Nature , vol.430 , pp. 631-639
    • Mattson, M.P.1
  • 3
    • 0041846404 scopus 로고    scopus 로고
    • Quantitative assessment of DNA fragmentation and β-amyloid deposition in insular cortex and midfrontal gyrus from patients with Alzheimer's disease
    • Colurso GJ, Nilson JE, Vervoort LG. Quantitative assessment of DNA fragmentation and β-amyloid deposition in insular cortex and midfrontal gyrus from patients with Alzheimer's disease. Life Sci. 2003;73:1795-1803.
    • (2003) Life Sci , vol.73 , pp. 1795-1803
    • Colurso, G.J.1    Nilson, J.E.2    Vervoort, L.G.3
  • 4
    • 0034329742 scopus 로고    scopus 로고
    • Apoptosis in neurodegenerative disorders
    • Mattson MP. Apoptosis in neurodegenerative disorders. Nat Rev Mol Cell Biol. 2000;1:120-129.
    • (2000) Nat Rev Mol Cell Biol , vol.1 , pp. 120-129
    • Mattson, M.P.1
  • 5
    • 0037417220 scopus 로고    scopus 로고
    • Apoptosis and caspases in neurodegenerative diseases
    • Friedlander RM. Apoptosis and caspases in neurodegenerative diseases. N Engl J Med. 2003;348:1365-1375.
    • (2003) N Engl J Med , vol.348 , pp. 1365-1375
    • Friedlander, R.M.1
  • 7
    • 4043086952 scopus 로고    scopus 로고
    • Mitochondria in health and disease: Perspectives on a new mitochondrial biology
    • Duchen MR. Mitochondria in health and disease: perspectives on a new mitochondrial biology. Mol Aspects Med. 2004;25:365-151.
    • (2004) Mol Aspects Med , vol.25 , pp. 365-151
    • Duchen, M.R.1
  • 8
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner MO. The biochemistry of apoptosis. Nature. 2000;407:770-776.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 9
    • 0034996104 scopus 로고    scopus 로고
    • Mitochondrial function and Alzheimer's disease
    • Ojaimi J, Byrne E. Mitochondrial function and Alzheimer's disease. Biol Signals Recept. 2001;10:254-262.
    • (2001) Biol Signals Recept , vol.10 , pp. 254-262
    • Ojaimi, J.1    Byrne, E.2
  • 11
    • 3042513691 scopus 로고    scopus 로고
    • Mitochondria dysfunction of Alzheimer's disease cybrids enhances Aβ toxicity
    • Cardoso SM, Santana I, Swerdlow RH, Oliveira CR. Mitochondria dysfunction of Alzheimer's disease cybrids enhances Aβ toxicity. J Neurochem. 2004;89:1417-1426.
    • (2004) J Neurochem , vol.89 , pp. 1417-1426
    • Cardoso, S.M.1    Santana, I.2    Swerdlow, R.H.3    Oliveira, C.R.4
  • 13
    • 1642499152 scopus 로고    scopus 로고
    • β-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase
    • Abramov AY, Canevari L, Duchen MR. β-Amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase. J Neurosci. 2004;24:565-575.
    • (2004) J Neurosci , vol.24 , pp. 565-575
    • Abramov, A.Y.1    Canevari, L.2    Duchen, M.R.3
  • 15
    • 0037112194 scopus 로고    scopus 로고
    • Amyloid-β induces Smac release via AP-1/Bim activation in cerebral endothelial cells
    • Yin KJ, Lee JM, Chen SD, Xu J, Hsu CY. Amyloid-β induces Smac release via AP-1/Bim activation in cerebral endothelial cells. J Neurosci. 2002;22:9764-9770.
    • (2002) J Neurosci , vol.22 , pp. 9764-9770
    • Yin, K.J.1    Lee, J.M.2    Chen, S.D.3    Xu, J.4    Hsu, C.Y.5
  • 17
    • 9644272489 scopus 로고    scopus 로고
    • Amyloid β-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis
    • Keil U, Bonert A, Marques CA, Scherping I, Weyermann J, Strosznajder JB, et al. Amyloid β-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis. J Biol Chem. 2004;279:50310-50320.
    • (2004) J Biol Chem , vol.279 , pp. 50310-50320
    • Keil, U.1    Bonert, A.2    Marques, C.A.3    Scherping, I.4    Weyermann, J.5    Strosznajder, J.B.6
  • 18
    • 11144353586 scopus 로고    scopus 로고
    • ABAD directly links Aβ to mitochondrial toxicity in Alzheimer's disease
    • Lustbader JW, Cirilli M, Lin C, Xu HW, Takuma K, Wang N, et al. ABAD directly links Aβ to mitochondrial toxicity in Alzheimer's disease. Science. 2004;304:448-452.
    • (2004) Science , vol.304 , pp. 448-452
    • Lustbader, J.W.1    Cirilli, M.2    Lin, C.3    Xu, H.W.4    Takuma, K.5    Wang, N.6
  • 19
    • 20144388830 scopus 로고    scopus 로고
    • ABAD enhances Aβ-induced cell stress via mitochondrial dysfunction
    • In press
    • Takuma K, Yao J, Huang J, Xu H, Chen X, Luddy J, et al. ABAD enhances Aβ-induced cell stress via mitochondrial dysfunction. FASEB J. In press 2005.
    • (2005) FASEB J
    • Takuma, K.1    Yao, J.2    Huang, J.3    Xu, H.4    Chen, X.5    Luddy, J.6
  • 20
    • 1842843860 scopus 로고    scopus 로고
    • Coupling endoplasmic reticulum stress to the cell death program
    • Rao RV, Ellerby HM, Bredesen DE. Coupling endoplasmic reticulum stress to the cell death program. Cell Death Differ. 2004;11:372-380.
    • (2004) Cell Death Differ , vol.11 , pp. 372-380
    • Rao, R.V.1    Ellerby, H.M.2    Bredesen, D.E.3
  • 21
    • 0033562966 scopus 로고    scopus 로고
    • Stress signaling from the lumen of the endoplasmic reticulum: Coordination of gene transcriptional and translational controls
    • Kaufman RJ. Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev. 1999;13:1211-1233.
    • (1999) Genes Dev , vol.13 , pp. 1211-1233
    • Kaufman, R.J.1
  • 23
    • 0036452908 scopus 로고    scopus 로고
    • Presenilin-1 mutations sensitize neurons to DNA damage-induced death by a mechanism involving perturbed calcium homeostasis and activation of calpains and caspase-12
    • Chan SL, Culmsee C, Haughey N, Klapper W, Mattson MP. Presenilin-1 mutations sensitize neurons to DNA damage-induced death by a mechanism involving perturbed calcium homeostasis and activation of calpains and caspase-12. Neurobiol Dis. 2002;11:2-19.
    • (2002) Neurobiol Dis , vol.11 , pp. 2-19
    • Chan, S.L.1    Culmsee, C.2    Haughey, N.3    Klapper, W.4    Mattson, M.P.5
  • 27
    • 1342344129 scopus 로고    scopus 로고
    • Clinical, pathological, and biochemical spectrum of Alzheimer disease associated with PS-1 mutations
    • Lleo A, Berezovska O, Growdon JH, Hyman BT. Clinical, pathological, and biochemical spectrum of Alzheimer disease associated with PS-1 mutations. Am J Geriatr Psychiatry. 2004;12:146-156.
    • (2004) Am J Geriatr Psychiatry , vol.12 , pp. 146-156
    • Lleo, A.1    Berezovska, O.2    Growdon, J.H.3    Hyman, B.T.4
  • 28
    • 0037066724 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-inducible protein, Herp, enhances presenilin-mediated generation of amyloid β-protein
    • Sai X, Kawamura Y, Kokame K, Yamaguchi H, Shiraishi H, Suzuki R, et al. Endoplasmic reticulum stress-inducible protein, Herp, enhances presenilin-mediated generation of amyloid β-protein. J Biol Chem. 2002;277:12915-12920.
    • (2002) J Biol Chem , vol.277 , pp. 12915-12920
    • Sai, X.1    Kawamura, Y.2    Kokame, K.3    Yamaguchi, H.4    Shiraishi, H.5    Suzuki, R.6
  • 29
    • 0034698878 scopus 로고    scopus 로고
    • Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis
    • Nakagawa T, Yuan J. Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J Cell Biol. 2000;150:887-894.
    • (2000) J Cell Biol , vol.150 , pp. 887-894
    • Nakagawa, T.1    Yuan, J.2
  • 30
    • 0347695007 scopus 로고    scopus 로고
    • Reduction of calcium release from the endoplasmic reticulum could only provide partial neuroprotection against β-amyloid peptide toxicity
    • Suen KC, Lin KF, Elyaman W, So KF, Chang RC, Hugon J. Reduction of calcium release from the endoplasmic reticulum could only provide partial neuroprotection against β-amyloid peptide toxicity. J Neurochem. 2003;87:1413-1426.
    • (2003) J Neurochem , vol.87 , pp. 1413-1426
    • Suen, K.C.1    Lin, K.F.2    Elyaman, W.3    So, K.F.4    Chang, R.C.5    Hugon, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.