Increased expression of heat shock protein-70 protects A549 cells against hyperoxia

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 275, Issue 4 19-4, 1998, Pages

  Wong, Hector R ^a   Menendez, Ingrid Y ^a   Ryan, Marnie A ^a   Denenberg, Alvin G ^a   Wispé, Jonathan R ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Adenosine 5' triphosphate; Epithelium; Isoprostanes; Lung; Oxidants; Stress proteins

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTIOXIDANT; CATALASE; COMPLEMENTARY DNA; GLUTATHIONE PEROXIDASE; HEAT SHOCK PROTEIN 70; MANGANESE SUPEROXIDE DISMUTASE;

ANTIOXIDANT ACTIVITY; ARTICLE; CYTOMEGALOVIRUS; DRUG CYTOTOXICITY; HUMAN; HUMAN CELL; HYPEROXIA; LIPID PEROXIDATION; LUNG INJURY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0031755888     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1998.275.4.l836     Document Type: Article

References (20)

1. Allen, C. B., and C. W. White. Glucose modulates cell death due to normobaric hyperoxia by maintaining cellular ATP. Am. J. Physiol. 274 (Lung Cell Mol. Physiol. 18): L159-L164, 1998.
2. Jenkinson, S. G. Oxygen toxicity. New. Horiz. 1: 504-511, 1993.
3. Kazzaz, J. A., J. Xu, T. A. Palaia, L. Mantell, A. M. Fein, and S. Horowitz. Cellular oxygen injury toxicity: oxidant injury without apoptosis. J. Biol. Chem. 271: 15182-15186, 1996.
4. Lee, P. J., J. Alam, G. W. Wiegand, and A. M. K. Choi. Overexpression of heme oxygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia. Proc. Natl. Acad. Sci. USA 93: 10393-10398, 1996.
5. Li, G. C., L. Li., Y. K. Liu, J. Y. Mak, L. Chen, and W. M. F. Lee. Thermal response of rat fibroblasts stably transfected with human 70-kD heat shock protein-encoding gene. Proc. Natl. Acad. Sci. USA 89: 2036-2040, 1992.
6. Marber, M. S., R. Mestril, S. H. Chi, M. R. Sayen, D. M. Yellon, and W. H. Dillman. Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury. J. Clin. Invest. 95: 1446-1456, 1995.
7. Morrow, J. D., and L. J. Roberts. The isoprostanes. Current knowledge and directions for future research. Biochem. Pharmacol. 51: 1-9, 1996.
8. Pardo, F. S., R. G. Bristow, A. Taghian, A. Ong, and C. Borek. Role of transfection and clonal selection in mediating radioresistance. Proc. Natl. Acad. Sci. USA 88: 10652-10656, 1991.
9. Pitt, B. R., M. Schwarz, E. S. Woo, E. Yee, K. Wasserloos, S. Tran, W. Weng, R. J. Mannix, S. A. Watkins, Y. Y. Tyurina, V. A. Tyurin, V. E. Kagan, and J. S. Lazo. Overexpression of metallothionein decreases sensitivity of pulmonary endothelial cells to oxidant injury. Am. J. Physiol. 273 (Lung Cell. Mol. Physiol. 17): L856-L865, 1997.
10. Polla, B. S., S. Kantengwa, D. Francois, S. Salvioli, C. Franceschi, C. Marsac, and A. Cossarizza. Mitochondria are selective targets for the protective effects of heat shock against oxidative injury. Proc. Natl. Acad. Sci. USA 93: 6458-6463, 1996.
11. Schwarz, M. A., J. S. Lazo, J. C. Yalowich, I. Reynolds, V. E. Kagan, V. Tyurin, Y. M. Kim, S. C. Watkins, and B. R. Pitt. Cytoplasmic metallothionein overexpression protects NIH3T3 cells from tert butyl hydroperoxide toxicity. J. Biol. Chem. 269: 15238-15243, 1994.
12. Simon, M. M., A. Reikerstorfer, A. Schwarz, C. Kronis, T. A. Luger, M. Jäätelä, and T. Schwarz. Heat shock protein 70 overexpression affects the response to ultraviolet light in murine fibroblasts. J. Clin. Invest. 95: 926-933, 1995.
13. Strand, C., J. B. Warshaw, K. Snow, and H. C. Jacobs. Heat shock does not induce tolerance to hyperoxia. Lung 172: 79-89, 1994.
14. Warner, B., R. Papes, M. Heile, D. Spitz, and J. Wispé. Expression of human MnSOD in Chinese hamster ovary cells confers protection from oxidant injury. Am. J. Physiol. 264 (Lung Cell. Mol. Physiol. 8): L598-L605, 1993.
15. Wispé, J. R., and R. J. Roberts. Molecular basis of pulmonary oxygen toxicity. Clin. Perinatol. 14: 651-666, 1987.
16. Wispé, J. R., B. B. Warner, J. C. Clark, C. R. Dey, J. Neuman, S. W. Glasser, J. Crapo, L. Y. Chang, and J. A. Whitsett. Human Mn-superoxide dismutase in pulmonary epithelial cells of transgenic mice confers protection from oxygen injury. J. Biol. Chem. 267: 23937-23941, 1992.
17. Wong, H. R., R. J. Mannix, J. M. Rusnak, A. Boota, H. Zar, S. C. Watkins, J. S. Lazo, and B. R. Pitt. The heat shock response attenuates lipopolysaccharide-mediated apoptosis in cultured sheep pulmonary artery endothelial cells. Am. J. Respir. Cell Mol. Biol. 15: 745-751, 1996.
18. Wong, H. R., M. Ryan, I. Y. Menendez, A. Denenberg, and J. R. Wispé. Heat shock protein induction protects human respiratory epithelium against nitric oxide-mediated cytotoxicity. Shock 8: 213-218, 1997.
19. Wong, H. R., M. Ryan, and J. R. Wispé. Stress response decreases NF-κB translocation and increases I-κBα expression in A549 cells. J. Clin. Invest. 99: 2423-2428, 1997.
20. Wong, H. R., and J. R. Wispé. The stress response and the lung. Am. J. Physiol. 273 (Lung Cell. Mol. Physiol. 17): L1-L9, 1997.