Binding affinities for sulfonamide inhibitors with matrix metalloproteinase-2 using a linear response method

Journal of Cellular and Molecular Medicine

Volumn 8, Issue 4, 2004, Pages 551-562

  Svab, Istvan ^a   Alexandru, D ^a   Vitos, Gabriella ^b   Flonta, Maria Luiza ^c  

^a INSTITUTE OF CELLULAR BIOLOGY AND PATHOLOGY NICOLAE SIMIONESCU   (Romania)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF BUCHAREST   (Romania)

Author keywords

Binding affinity; Linear interaction energy method; Matrix metalloproteinase 2; Sulfonamide

Indexed keywords

ENZYME INHIBITOR; GELATINASE A; HYDROXAMIC ACID; LIGAND; ORGANIC COMPOUND; PHENYLALANINE; SULFONAMIDE;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; DISEASE COURSE; DRUG ANTAGONISM; HYDROGEN BOND; IC 50; KINETICS; METABOLISM; METASTASIS; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING; STATISTICAL MODEL; THERMODYNAMICS;

AMINO ACID SEQUENCE; DISEASE PROGRESSION; ENZYME INHIBITORS; HYDROGEN BONDING; HYDROXAMIC ACIDS; INHIBITORY CONCENTRATION 50; KINETICS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MATRIX METALLOPROTEINASE 2; MODELS, CHEMICAL; MODELS, MOLECULAR; MODELS, STATISTICAL; MOLECULAR SEQUENCE DATA; NEOPLASM METASTASIS; ORGANIC CHEMICALS; PHENYLALANINE; PROTEIN BINDING; SULFONAMIDES; THERMODYNAMICS;

EID: 16644394595     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2004.tb00480.x     Document Type: Article

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