메뉴 건너뛰기




Volumn 295, Issue 1, 2004, Pages 9-24

Cell differentiation, caspase inhibition, and macromolecular synthesis blockage, but not BCL-2 or BCL-XL proteins, protect SH-SY5Y cells from apoptosis triggered by two CDK inhibitory drugs

Author keywords

Apoptosis; Bcl 2; Bcl XL; Caspase; CDK; Cycloheximide; Erk; Olomoucine; Roscovitine; SH SY5Y

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CASPASE INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR; DACTINOMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; OLOMOUCINE; PROTEIN BCL 2; PROTEIN BCL XL; ROSCOVITINE; UO 126;

EID: 1642502384     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2003.12.019     Document Type: Article
Times cited : (36)

References (47)
  • 2
    • 0026693966 scopus 로고
    • Animal cell cycles and their control
    • Norbury C., Nurse P. Animal cell cycles and their control. Annu. Rev. Biochem. 61:1992;441-470.
    • (1992) Annu. Rev. Biochem. , vol.61 , pp. 441-470
    • Norbury, C.1    Nurse, P.2
  • 5
    • 0036220822 scopus 로고    scopus 로고
    • Complexities in the development of cyclin-dependent kinase inhibitor drugs
    • Sausville E.A. Complexities in the development of cyclin-dependent kinase inhibitor drugs. Trends Mol. Med. 8:2002;S32-S37.
    • (2002) Trends Mol. Med. , vol.8
    • Sausville, E.A.1
  • 9
    • 0036273353 scopus 로고    scopus 로고
    • The prevention of the staurosporine-induced apoptosis by Bcl-X(L), but not by Bcl-2 or caspase inhibitors, allows the extensive differentiation of human neuroblastoma cells
    • Yuste V.J., Sanchez-Lopez I., Sole C., Encinas M., Bayascas J.R., Boix J., Comella J.X. The prevention of the staurosporine-induced apoptosis by Bcl-X(L), but not by Bcl-2 or caspase inhibitors, allows the extensive differentiation of human neuroblastoma cells. J. Neurochem. 80:2002;126-139.
    • (2002) J. Neurochem. , vol.80 , pp. 126-139
    • Yuste, V.J.1    Sanchez-Lopez, I.2    Sole, C.3    Encinas, M.4    Bayascas, J.R.5    Boix, J.6    Comella, J.X.7
  • 10
    • 2642689658 scopus 로고    scopus 로고
    • Proteases to die for
    • Cryns V., Yuan J. Proteases to die for. Genes Dev. 12:1998;1551-1570.
    • (1998) Genes Dev. , vol.12 , pp. 1551-1570
    • Cryns, V.1    Yuan, J.2
  • 11
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry N.A., Lazebnik Y. Caspases: enemies within. Science. 281:1998;1312-1316.
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.2
  • 13
    • 0242432345 scopus 로고    scopus 로고
    • Many cuts to ruin: A comprehensive update of caspase substrates
    • Fischer U., Jänicke R.U., Schulze-Osthoff K. Many cuts to ruin: a comprehensive update of caspase substrates. Cell Death Differ. 10:2003;76-100.
    • (2003) Cell Death Differ. , vol.10 , pp. 76-100
    • Fischer, U.1    Jänicke, R.U.2    Schulze-Osthoff, K.3
  • 14
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi A., Dixit V.M. Death receptors: signaling and modulation. Science. 281:1998;1305-1308.
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 15
    • 0036899079 scopus 로고    scopus 로고
    • Apoptosomes: Engines for caspase activation
    • Adams J.M., Cory S. Apoptosomes: engines for caspase activation. Curr. Opin. Cell Biol. 14:1998;715-720.
    • (1998) Curr. Opin. Cell Biol. , vol.14 , pp. 715-720
    • Adams, J.M.1    Cory, S.2
  • 16
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • Adams J.M., Cory S. The Bcl-2 protein family: arbiters of cell survival. Science. 281:1998;1322-1326.
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 17
    • 0030788099 scopus 로고    scopus 로고
    • Characterization of the cell death process induced by staurosporine in human neuroblastoma cell lines
    • Boix J., Llecha N., Yuste V.J., Comella J.X. Characterization of the cell death process induced by staurosporine in human neuroblastoma cell lines. Neuropharmacology. 36:1997;811-821.
    • (1997) Neuropharmacology , vol.36 , pp. 811-821
    • Boix, J.1    Llecha, N.2    Yuste, V.J.3    Comella, J.X.4
  • 18
    • 0035933798 scopus 로고    scopus 로고
    • The absence of oligonucleosomal DNA fragmentation during apoptosis of IMR-5 neuroblastoma cells: Disappearance of the caspase-activated DNase
    • Yuste V.J., Bayascas J.R., Llecha N., Sanchez-Lopez I., Boix J., Comella J.X. The absence of oligonucleosomal DNA fragmentation during apoptosis of IMR-5 neuroblastoma cells: disappearance of the caspase-activated DNase. J. Biol. Chem. 276:2001;22323-22331.
    • (2001) J. Biol. Chem. , vol.276 , pp. 22323-22331
    • Yuste, V.J.1    Bayascas, J.R.2    Llecha, N.3    Sanchez-Lopez, I.4    Boix, J.5    Comella, J.X.6
  • 19
    • 0033844835 scopus 로고    scopus 로고
    • Sequential treatment of SH-SY5Y cells with retinoic acid and brain-derived neurotrophic factor gives rise to fully differentiated, neurotrophic factor-dependent, human neuron-like cells
    • Encinas M., Iglesias M., Liu Y., Wang H., Muhaisen A., Ceña V., Gallego C., Comella J.X. Sequential treatment of SH-SY5Y cells with retinoic acid and brain-derived neurotrophic factor gives rise to fully differentiated, neurotrophic factor-dependent, human neuron-like cells. J. Neurochem. 75:2002;991-1003.
    • (2002) J. Neurochem. , vol.75 , pp. 991-1003
    • Encinas, M.1    Iglesias, M.2    Liu, Y.3    Wang, H.4    Muhaisen, A.5    Ceña, V.6    Gallego, C.7    Comella, J.X.8
  • 20
    • 0002641250 scopus 로고    scopus 로고
    • Assays for the measurement of DNA fragmentation during apoptosis
    • T.G. Cotter, & S.J. Martin. London: Portland Press
    • Wolfe J.T., Pringle J.H., Cohen G.M. Assays for the measurement of DNA fragmentation during apoptosis. Cotter T.G., Martin S.J. Techniques in Apoptosis. 1996;51-69 Portland Press, London.
    • (1996) Techniques in Apoptosis , pp. 51-69
    • Wolfe, J.T.1    Pringle, J.H.2    Cohen, G.M.3
  • 24
    • 0034644659 scopus 로고    scopus 로고
    • Bcl-2 independence of flavopiridol-induced apoptosis. Mitochondrial depolarization in the absence of cytochrome c release
    • Achenbach T.V., Muller R., Slater E.P. Bcl-2 independence of flavopiridol-induced apoptosis. Mitochondrial depolarization in the absence of cytochrome c release. J. Biol. Chem. 275:2002;32089-32097.
    • (2002) J. Biol. Chem. , vol.275 , pp. 32089-32097
    • Achenbach, T.V.1    Muller, R.2    Slater, E.P.3
  • 25
    • 0034935026 scopus 로고    scopus 로고
    • Flavopiridol circumvents Bcl-2 family mediated inhibition of apoptosis and drug resistance in B-cell chronic lymphocytic leukaemia
    • Pepper C., Thomas A., Hoy T., Fegan C., Bentley P. Flavopiridol circumvents Bcl-2 family mediated inhibition of apoptosis and drug resistance in B-cell chronic lymphocytic leukaemia. Br. J. Haematol. 114:2001;70-77.
    • (2001) Br. J. Haematol. , vol.114 , pp. 70-77
    • Pepper, C.1    Thomas, A.2    Hoy, T.3    Fegan, C.4    Bentley, P.5
  • 27
    • 0037446980 scopus 로고    scopus 로고
    • The lethal effects of pharmacological cyclin-dependent kinase inhibitors in human leukemia cells proceed through a phosphatidylinositol 3-kinase/Akt-dependent process
    • Yu C., Rahmani M., Dai Y., Conrad D., Krystal G., Dent P., Grant S. The lethal effects of pharmacological cyclin-dependent kinase inhibitors in human leukemia cells proceed through a phosphatidylinositol 3-kinase/Akt-dependent process. Cancer Res. 63:2003;1822-1833.
    • (2003) Cancer Res. , vol.63 , pp. 1822-1833
    • Yu, C.1    Rahmani, M.2    Dai, Y.3    Conrad, D.4    Krystal, G.5    Dent, P.6    Grant, S.7
  • 28
    • 0036490855 scopus 로고    scopus 로고
    • Induction of apoptosis in human leukemia cells by the CDK1 inhibitor CGP74514A
    • Dai Y., Dent P., Grant S. Induction of apoptosis in human leukemia cells by the CDK1 inhibitor CGP74514A. Cell Cycle. 1:2002;142-143.
    • (2002) Cell Cycle , vol.1 , pp. 142-143
    • Dai, Y.1    Dent, P.2    Grant, S.3
  • 29
    • 0035736259 scopus 로고    scopus 로고
    • Organelle-specific initiation of cell death pathways
    • Ferri K.F., Kroemer G. Organelle-specific initiation of cell death pathways. Nat. Cell Biol. 3:2001;E255-E263.
    • (2001) Nat. Cell Biol. , vol.3
    • Ferri, K.F.1    Kroemer, G.2
  • 31
    • 0029904810 scopus 로고    scopus 로고
    • Flavopiridol: A cytotoxic flavone that induces cell death in noncycling A549 human lung carcinoma cells
    • Bible K.C., Kaufmann S.H. Flavopiridol: a cytotoxic flavone that induces cell death in noncycling A549 human lung carcinoma cells. Cancer Res. 56:1996;4856-4861.
    • (1996) Cancer Res. , vol.56 , pp. 4856-4861
    • Bible, K.C.1    Kaufmann, S.H.2
  • 32
    • 0032004518 scopus 로고    scopus 로고
    • Serum deprivation and protein synthesis inhibition induce two different apoptotic processes in N18 neuroblastoma cells
    • Boix J., Fibla J., Yuste V.J., Piulats J.M., Llecha N., Comella J.X. Serum deprivation and protein synthesis inhibition induce two different apoptotic processes in N18 neuroblastoma cells. Exp. Cell Res. 238:1998;422-429.
    • (1998) Exp. Cell Res. , vol.238 , pp. 422-429
    • Boix, J.1    Fibla, J.2    Yuste, V.J.3    Piulats, J.M.4    Llecha, N.5    Comella, J.X.6
  • 33
    • 0028246870 scopus 로고
    • Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione
    • Ratan R.R., Murphy T.H., Baraban J.M. Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione. J. Neurosci. 14:1994;4385-4392.
    • (1994) J. Neurosci. , vol.14 , pp. 4385-4392
    • Ratan, R.R.1    Murphy, T.H.2    Baraban, J.M.3
  • 34
    • 0030855972 scopus 로고    scopus 로고
    • Coupling cell division to cell growth by translational control of the G1 cyclin CLN3 in yeast
    • Polymenis M., Schmidt E.V. Coupling cell division to cell growth by translational control of the G1 cyclin CLN3 in yeast. Genes Dev. 11:1997;2522-2531.
    • (1997) Genes Dev. , vol.11 , pp. 2522-2531
    • Polymenis, M.1    Schmidt, E.V.2
  • 35
    • 0032479988 scopus 로고    scopus 로고
    • Regulation of the Cln3-Cdc28 kinase by cAMP in Saccharomyces cerevisiae
    • Hall D.D., Markwardt D.D., Parviz F., Heideman W. Regulation of the Cln3-Cdc28 kinase by cAMP in Saccharomyces cerevisiae. EMBO J. 17:1998;4370-4378.
    • (1998) EMBO J. , vol.17 , pp. 4370-4378
    • Hall, D.D.1    Markwardt, D.D.2    Parviz, F.3    Heideman, W.4
  • 36
    • 0032535140 scopus 로고    scopus 로고
    • A link between cell cycle and cell death: Bax and Bcl-2 modulate Cdk2 activation during thymocyte apoptosis
    • Gil-Gomez G., Berns A., Brady H.J. A link between cell cycle and cell death: Bax and Bcl-2 modulate Cdk2 activation during thymocyte apoptosis. EMBO J. 17:1998;7209-7218.
    • (1998) EMBO J. , vol.17 , pp. 7209-7218
    • Gil-Gomez, G.1    Berns, A.2    Brady, H.J.3
  • 37
    • 0033559980 scopus 로고    scopus 로고
    • The cyclin-dependent kinase Cdk2 regulates thymocyte apoptosis
    • Hakem A., Sasaki T., Kozieradzki I., Penninger J.M. The cyclin-dependent kinase Cdk2 regulates thymocyte apoptosis. J. Exp. Med. 189:1999;957-968.
    • (1999) J. Exp. Med. , vol.189 , pp. 957-968
    • Hakem, A.1    Sasaki, T.2    Kozieradzki, I.3    Penninger, J.M.4
  • 38
    • 0029913242 scopus 로고    scopus 로고
    • Inhibitors of cyclin-dependent kinases promote survival of post-mitotic neuronally differentiated PC12 cells and sympathetic neurons
    • Park D.S., Farinelli S.E., Greene L.A. Inhibitors of cyclin-dependent kinases promote survival of post-mitotic neuronally differentiated PC12 cells and sympathetic neurons. J. Biol. Chem. 271:1996;8161-8169.
    • (1996) J. Biol. Chem. , vol.271 , pp. 8161-8169
    • Park, D.S.1    Farinelli, S.E.2    Greene, L.A.3
  • 39
    • 0033570320 scopus 로고    scopus 로고
    • Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis
    • Padmanabhan J., Park D.S., Greene L.A., Shelanski M.L. Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis. J. Neurosci. 19:1999;8747-8756.
    • (1999) J. Neurosci. , vol.19 , pp. 8747-8756
    • Padmanabhan, J.1    Park, D.S.2    Greene, L.A.3    Shelanski, M.L.4
  • 40
  • 42
    • 0027320760 scopus 로고
    • A system for characterizing cellular and molecular events in programmed neuronal cell death
    • Pittman R.N., Wang S., DiBenedetto A.J., Mills J.C. A system for characterizing cellular and molecular events in programmed neuronal cell death. J. Neurosci. 13:1993;3669-3680.
    • (1993) J. Neurosci. , vol.13 , pp. 3669-3680
    • Pittman, R.N.1    Wang, S.2    Dibenedetto, A.J.3    Mills, J.C.4
  • 43
    • 0029954311 scopus 로고    scopus 로고
    • Potassium deprivation-induced apoptosis of cerebellar granule neurons: A sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species
    • Schulz J.B., Weller M., Klockgether T. Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species. J. Neurosci. 16:1996;4696-4706.
    • (1996) J. Neurosci. , vol.16 , pp. 4696-4706
    • Schulz, J.B.1    Weller, M.2    Klockgether, T.3
  • 44
    • 0037086282 scopus 로고    scopus 로고
    • Selective sensitization of transformed cells to Flavopiridol-induced apoptosis following recruitment to S-Phase
    • Matranga C.B., Shapiro G.I. Selective sensitization of transformed cells to Flavopiridol-induced apoptosis following recruitment to S-Phase. Cancer Res. 62:2002;1707-1717.
    • (2002) Cancer Res. , vol.62 , pp. 1707-1717
    • Matranga, C.B.1    Shapiro, G.I.2
  • 45
    • 0036709880 scopus 로고    scopus 로고
    • Identifying in vivo targets of cyclin-dependent kinase inhibitors by affinity chromatography
    • Knockaert M., Meijer L. Identifying in vivo targets of cyclin-dependent kinase inhibitors by affinity chromatography. Biochem. Pharmacol. 64:2002;819-825.
    • (2002) Biochem. Pharmacol. , vol.64 , pp. 819-825
    • Knockaert, M.1    Meijer, L.2
  • 46
    • 0036147535 scopus 로고    scopus 로고
    • The cyclin-dependent kinase inhibitor roscovitine inhibits the transactivating activity and alters the posttranslational modification of herpes simplex virus type 1 ICP0
    • Davido D.J., Leib D.A., Schaffer P.A. The cyclin-dependent kinase inhibitor roscovitine inhibits the transactivating activity and alters the posttranslational modification of herpes simplex virus type 1 ICP0. J. Virol. 76:2002;1077-1088.
    • (2002) J. Virol. , vol.76 , pp. 1077-1088
    • Davido, D.J.1    Leib, D.A.2    Schaffer, P.A.3
  • 47
    • 0034812298 scopus 로고    scopus 로고
    • The cyclin-dependent kinase inhibitor Roscovitine inhibits RNA synthesis and triggers nuclear accumulation of p53 that is unmodified at Ser15 and Lys382
    • Ljungman M., Paulsen M.T. The cyclin-dependent kinase inhibitor Roscovitine inhibits RNA synthesis and triggers nuclear accumulation of p53 that is unmodified at Ser15 and Lys382. Mol. Pharmacol. 60:2001;785-789.
    • (2001) Mol. Pharmacol. , vol.60 , pp. 785-789
    • Ljungman, M.1    Paulsen, M.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.