The cyclin-dependent kinase inhibitor roscovitine inhibits RNA synthesis and triggers nuclear accumulation of p53 that is unmodified at Ser15 and Lys382

Molecular Pharmacology

Volumn 60, Issue 4, 2001, Pages 785-789

  Ljungman, Mats ^a,b   Paulsen, Michelle T ^a  

^a UNIVERSITY OF MICHIGAN COMPREHENSIVE CANCER CENTER   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; LYSINE; PROTEIN P53; ROSCOVITINE; SERINE;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS; CONTROLLED STUDY; DOSE RESPONSE; ENZYME INHIBITION; FIBROBLAST; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; RNA SYNTHESIS; TRANSCRIPTION REGULATION;

CDC2-CDC28 KINASES; CELL NUCLEUS; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASES; ENZYME INHIBITORS; HUMANS; LYSINE; NUCLEIC ACID SYNTHESIS INHIBITORS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PURINES; RNA POLYMERASE II; RNA, MESSENGER; SERINE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0034812298     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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