Induction of apoptosis in human leukemia cells by the CDK1 inhibitor CGP74514A.

Cell cycle (Georgetown, Tex.)

Volumn 1, Issue 2, 2002, Pages 143-152

  Dai, Yun ^a   Dent, Paul ^a   Grant, Steven ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOPURINE; CASP8 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; CASPASE; CASPASE 8; CASPASE 9; CDK4 PROTEIN, HUMAN; CDKN1A PROTEIN, HUMAN; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLINE; DNA BINDING PROTEIN; DRUG DERIVATIVE; E2F1 PROTEIN, HUMAN; INTERLEUKIN 1BETA CONVERTING ENZYME INHIBITOR; INTERLEUKIN-1BETA-CONVERTING ENZYME INHIBITOR; ISOLEUCYL GLUTAMYL THREONYL ASPARTIC ACID FLUOROMETHYL KETONE; ISOLEUCYL-GLUTAMYL-THREONYL-ASPARTIC ACID FLUOROMETHYL KETONE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; N(2) (2 AMINOCYCLOHEXYL) N(6) (3 CHLOROPHENYL) 9 ETHYL 9H PURINE 2,6 DIAMINE; N(2)-(2-AMINOCYCLOHEXYL)-N(6)-(3-CHLOROPHENYL)-9-ETHYL-9H-PURINE-2,6-DIAMINE; OLIGOPEPTIDE; ONCOPROTEIN; PROTEIN BCL 2; RETINOBLASTOMA PROTEIN; SERINE PROTEINASE INHIBITOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR E2F1; TUMOR SUPPRESSOR PROTEIN; VIRUS PROTEIN;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL LINE; CELL MEMBRANE POTENTIAL; CELL STRAIN HL 60; CELL STRAIN U937; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; LEUKEMIA; METABOLISM; MITOCHONDRION; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

2-AMINOPURINE; APOPTOSIS; CASPASE 8; CASPASE 9; CASPASES; CDC2 PROTEIN KINASE; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; CYCLINS; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; E2F TRANSCRIPTION FACTORS; E2F1 TRANSCRIPTION FACTOR; HL-60 CELLS; HUMANS; LEUKEMIA; MEMBRANE POTENTIALS; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; OLIGOPEPTIDES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RETINOBLASTOMA PROTEIN; SERPINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS; U937 CELLS; VIRAL PROTEINS;

EID: 0036490855     PISSN: 15384101     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)