Modeling of substrate specificity of the Alzheimer's disease amyloid precursor protein β-secretase

Journal of Molecular Biology

Volumn 300, Issue 2, 2000, Pages 241-248

  Sauder, J Michael ^a   Arthur, Jonathan W ^a   Dunbrack Jr , Roland L ^a  

^a FOX CHASE CANCER CENTER   (United States)

Author keywords

Alzheimer's disease; APP; Aspartic protease; BACE; Homology modeling

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; ENZYME INHIBITOR; PEPSIN A; RENIN;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ARTICLE; COMPLEX FORMATION; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME SPECIFICITY; HUMAN; HUMAN TISSUE; MODEL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN STRUCTURE;

EID: 0034616960     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.3860     Document Type: Article

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