Atomic resolution structures of CTX-M β-lactamases: Extended spectrum activities from increased mobility and decreased stability

Journal of Molecular Biology

Volumn 348, Issue 2, 2005, Pages 349-362

  Chen, Yu ^a   Delmas, Julien ^b   Sirot, Jacques ^b   Shoichet, Brian ^a   Bonnet, Richard ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITÉ CLERMONT AUVERGNE   (France)

Author keywords

Antibiotic resistance; Enzyme motion; Third generation cephalosporins; X ray crystallography; lactamase

Indexed keywords

BETA LACTAMASE; CEFOTAXIME; CEFTAZIDIME; CTX M BETA LACTAMASE; PENICILLINASE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; ENZYME ACTIVITY; ENZYME STABILITY; ENZYME STRUCTURE; PRIORITY JOURNAL;

EID: 16244415566     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.02.010     Document Type: Article

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