-
1
-
-
0003799357
-
-
(Ed.): John Willy and sons, New York
-
M.E. Wolff (Ed.): Burger's Medicinal Chemistry. Part III, John Willy and sons, New York, 1981, pp. 1205-1271.
-
(1981)
Burger's Medicinal Chemistry
, Issue.PART III
, pp. 1205-1271
-
-
Wolff, M.E.1
-
2
-
-
0034897301
-
"Cyclooxygenase-2, P-glycoprotein-170 and drug resistance; is Chemoprevention against multidrug resistance possible"
-
D. Ratnasinghe, P.J. Daschner, M.R. Anver, B.H. Kasprzak, P.R.Taylor, G.C. Yeh and J.A. Tangrea: "Cyclooxygenase-2, P-glycoprotein-170 and drug resistance; is Chemoprevention against multidrug resistance possible", Anticancer Research, Vol. 21(3C), (2001), pp. 2141-2147.
-
(2001)
Anticancer Research
, vol.21
, Issue.3 C
, pp. 2141-2147
-
-
Ratnasinghe, D.1
Daschner, P.J.2
Anver, M.R.3
Kasprzak, B.H.4
Taylor, P.R.5
Yeh, G.C.6
Tangrea, J.A.7
-
3
-
-
0035033709
-
"Non steroidal anti-inflammatory drugs with activity against either cyclooxygenase 1 or cyclooxygenase 2 inhibit colorectal cancer in a DMH rodent model by inducing apoptosis and inhibiting cell proliferation"
-
W.A. Brown, S.A. Spinner, W.C. Malcontent, D. Vogiagis and P.E. O'Brien: "Non steroidal anti-inflammatory drugs with activity against either cyclooxygenase 1 or cyclooxygenase 2 inhibit colorectal cancer in a DMH rodent model by inducing apoptosis and inhibiting cell proliferation", Gut, Vol. 48(5), (2001), pp. 660-666.
-
(2001)
Gut
, vol.48
, Issue.5
, pp. 660-666
-
-
Brown, W.A.1
Spinner, S.A.2
Malcontent, W.C.3
Vogiagis, D.4
O'Brien, P.E.5
-
4
-
-
0032737556
-
"Cyclo-oxygenase-2, Pharmacology, physiology, biochemistry and relevance to NSAID therapy"
-
J.A. Mitchell and T.D. Warner: "Cyclo-oxygenase-2, Pharmacology, physiology, biochemistry and relevance to NSAID therapy", Br. J. Pharmacol., Vol. 128(6), (1999), pp. 1121-1132.
-
(1999)
Br. J. Pharmacol.
, vol.128
, Issue.6
, pp. 1121-1132
-
-
Mitchell, J.A.1
Warner, T.D.2
-
5
-
-
0032572548
-
"Recent consideration in non steroidal anti-inflammatory drug gastropathy"
-
G. Singh: "Recent consideration in non steroidal anti-inflammatory drug gastropathy", Am. J. Med., Vol. 105(1B), (1998), pp. 31S-38S.
-
(1998)
Am. J. Med.
, vol.105
, Issue.1 B
-
-
Singh, G.1
-
6
-
-
0032579939
-
"Variability in risk of gastrointestinal complications with different non steroidal anti-inflammatory drugs"
-
L.A. Garcia Rodriguez: "Variability in risk of gastrointestinal complications with different non steroidal anti-inflammatory drugs", Am. J. Med., Vol. 104, (1998), pp. 30S-34S.
-
(1998)
Am. J. Med.
, vol.104
-
-
Garcia Rodriguez, L.A.1
-
7
-
-
0024991557
-
"An updated safety profile of etodolac in several thousand patients"
-
M. Schattenkirchner: "An updated safety profile of etodolac in several thousand patients", Eur. J. Rheumatol. Inflamm., Vol. 10, (1990), pp. 56-65.
-
(1990)
Eur. J. Rheumatol. Inflamm.
, vol.10
, pp. 56-65
-
-
Schattenkirchner, M.1
-
8
-
-
0027475765
-
"Nabumetone. A reappraisal of its pharmacology and therapeutic use in rheumatic disease"
-
H.A. Friendel, H.D. Langtry and M.M. Buckley: "Nabumetone. A reappraisal of its pharmacology and therapeutic use in rheumatic disease", Drugs, Vol. 45, (1993), pp. 131-156.
-
(1993)
Drugs
, vol.45
, pp. 131-156
-
-
Friendel, H.A.1
Langtry, H.D.2
Buckley, M.M.3
-
9
-
-
33644622445
-
-
(Ed): American society of hospital pharmacists Inc., Bethesda
-
G.K. Mcevoy (Ed): AHFS drug information, American society of hospital pharmacists Inc., Bethesda, 1992, pp. 1041-1126.
-
(1992)
AHFS Drug Information
, pp. 1041-1126
-
-
Mcevoy, G.K.1
-
10
-
-
0025754779
-
"Expression of a nitrogen-responsive gene encoding prostaglandin synthase regulated by m-RNA splicing"
-
W.L. Xie et.al.: "Expression of a nitrogen-responsive gene encoding prostaglandin synthase regulated by m-RNA splicing", Proc. Natl. Acad. Sci USA, Vol. 88(7), (1991), pp. 2692-2696.
-
(1991)
Proc. Natl. Acad. Sci USA
, vol.88
, Issue.7
, pp. 2692-2696
-
-
Xie, W.L.1
-
11
-
-
0033971402
-
"Do cyclooxygenase-2 inhibitors provide benefits similar to those of traditional nonsteroidal anti-inflammatory drugs, with less gastrointestinal toxicity?"
-
M. Feldman and A.T. McMahan: "Do cyclooxygenase-2 inhibitors provide benefits similar to those of traditional nonsteroidal anti-inflammatory drugs, with less gastrointestinal toxicity?", Ann. Intern Med., Vol. 132(2), (2000), pp. 134-143.
-
(2000)
Ann. Intern Med.
, vol.132
, Issue.2
, pp. 134-143
-
-
Feldman, M.1
McMahan, A.T.2
-
12
-
-
0016227738
-
"Drugs which inhibit prostaglandin biosynthesis"
-
R.J. Flower: "Drugs which inhibit prostaglandin biosynthesis", Pharmacol. Rev., Vol. 26(1), (1974), pp. 33-67.
-
(1974)
Pharmacol. Rev.
, vol.26
, Issue.1
, pp. 33-67
-
-
Flower, R.J.1
-
13
-
-
0033031331
-
"COX-2 inhibitors"
-
C.J. Hawkey: "COX-2 inhibitors", Lancet, Vol. 353, (1999), pp. 307-314.
-
(1999)
Lancet
, vol.353
, pp. 307-314
-
-
Hawkey, C.J.1
-
14
-
-
0036099571
-
"Selective COX-2 Inhibitors and dual acting anti-inflammatory drugs: Critical remarks"
-
A. Bertolini, A. Ottani and M. Sandrini: "Selective COX-2 Inhibitors and dual acting anti-inflammatory drugs: Critical remarks", Current Medicinal Chemistry, Vol. 9(10), (2002), pp. 1033-1043.
-
(2002)
Current Medicinal Chemistry
, vol.9
, Issue.10
, pp. 1033-1043
-
-
Bertolini, A.1
Ottani, A.2
Sandrini, M.3
-
15
-
-
0034790657
-
"COX-2 inhibition. An advance or only pharmaceutical hype"
-
L.S. Simon, "COX-2 inhibition. An advance or only pharmaceutical hype", Arthritis care; Research, Vol. 45, (2001), pp. 209-215.
-
(2001)
Arthritis Care; Research
, vol.45
, pp. 209-215
-
-
Simon, L.S.1
-
16
-
-
0034771469
-
"Clinical potential of cyclooxygenase-2 inhibitiors"
-
J.A. Oviedo and M. Wolfe: "Clinical potential of cyclooxygenase-2 inhibitiors", Bio Drugs, Vol. 15, (2001), pp. 563-572.
-
(2001)
Bio Drugs
, vol.15
, pp. 563-572
-
-
Oviedo, J.A.1
Wolfe, M.2
-
17
-
-
0035699646
-
"Participation of COX, 1L-1β and TNFα in formalin-induced inflammatory pain"
-
V. Granados-Soto, R. Alonso-Lopez, R. Asomoza-Espinosa, M.O. Rufino, L.D. Gomes-Lopes and S.H. Ferrira: "Participation of COX, 1L-1β and TNFα in formalin-induced inflammatory pain", Proceedings of the Western Pharmacology Society, Vol. 44, (2001), pp. 15-17.
-
(2001)
Proceedings of the Western Pharmacology Society
, vol.44
, pp. 15-17
-
-
Granados-Soto, V.1
Alonso-Lopez, R.2
Asomoza-Espinosa, R.3
Rufino, M.O.4
Gomes-Lopes, L.D.5
Ferrira, S.H.6
-
18
-
-
0036124437
-
"Involvement of peripheral cyclooxygenase-1 and cyclooxygenase-2 in inflammatory pain"
-
R.V. Martinez, M. Reval, D. Irene, M.D. Campos, J.A. Terron, R.A.M. Dominguez and F.J. Lopez-Munoz: "Involvement of peripheral cyclooxygenase-1 and cyclooxygenase-2 in inflammatory pain", Journal of Pharmacy and Pharmacology, Vol. 54, (2002), pp. 405-412.
-
(2002)
Journal of Pharmacy and Pharmacology
, vol.54
, pp. 405-412
-
-
Martinez, R.V.1
Reval, M.2
Irene, D.3
Campos, M.D.4
Terron, J.A.5
Dominguez, R.A.M.6
Lopez-Munoz, F.J.7
-
19
-
-
33644624484
-
"Inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 regulates the microcirculation of the inflamed gall bladder"
-
B. Nilsson, S. Friman and J. Svanvik: "Inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 regulates the microcirculation of the inflamed gall bladder", Portland Press proceedings, Vol. 16, (2000), pp. 193;
-
(2000)
Portland Press Proceedings
, vol.16
, pp. 193
-
-
Nilsson, B.1
Friman, S.2
Svanvik, J.3
-
21
-
-
0035934250
-
"Interleukin 1-induced cyclooxygenase and nitric oxide synthase gene expression in the rat dorsal root ganglia is modulated antioxidants"
-
O.J. Igwe, J.N. Murray and A.S. Moolwaney: "Interleukin 1-induced cyclooxygenase and nitric oxide synthase gene expression in the rat dorsal root ganglia is modulated antioxidants", Neuroscience (Oxford), Vol. 105, (2001), pp. 971-985.
-
(2001)
Neuroscience (Oxford)
, vol.105
, pp. 971-985
-
-
Igwe, O.J.1
Murray, J.N.2
Moolwaney, A.S.3
-
22
-
-
0034838352
-
"Effect of local application of growth factors on gastric ulcer healing and mucosal expression of cyclooxygenase-1 and -2"
-
T. Brzozowski, P.C. Konfurek, S.J. Konfurek, D. Schuppan, D. Drozdowicz, S. Kwiecien, J. Majka, T. Nakamura and E.G. Hahn: "Effect of local application of growth factors on gastric ulcer healing and mucosal expression of cyclooxygenase-1 and -2", Digestion, Vol. 64, (2001), pp. 15-29.
-
(2001)
Digestion
, vol.64
, pp. 15-29
-
-
Brzozowski, T.1
Konfurek, P.C.2
Konfurek, S.J.3
Schuppan, D.4
Drozdowicz, D.5
Kwiecien, S.6
Majka, J.7
Nakamura, T.8
Hahn, E.G.9
-
23
-
-
0036521876
-
"Pathophysiological basis of acute inflammatory hyperemia in the rat knee: Roles of cyclo-oxygenase-1 and -2"
-
C.G. Egan, J.C. Lockhart, W.R. Ferrell, S.M. Day and J.S. Mclean: "Pathophysiological basis of acute inflammatory hyperemia in the rat knee: roles of cyclo-oxygenase-1 and -2", Journal of Physiology (Cambridge), Vol. 539, (2002), pp. 579-587.
-
(2002)
Journal of Physiology (Cambridge)
, vol.539
, pp. 579-587
-
-
Egan, C.G.1
Lockhart, J.C.2
Ferrell, W.R.3
Day, S.M.4
Mclean, J.S.5
-
24
-
-
0033851568
-
"NSAID- induced gastric damage in rats: Requirement for inhibition of both cyclooxygenase 1 and 2"
-
J.L. Wallace, W. Mc Knight, B.K. Reuter, N. Vergnolle: "NSAID- induced gastric damage in rats: Requirement for inhibition of both cyclooxygenase 1 and 2", Gastroenterology, Vol. 119, (2000), pp. 706-714.
-
(2000)
Gastroenterology
, vol.119
, pp. 706-714
-
-
Wallace, J.L.1
McKnight, W.2
Reuter, B.K.3
Vergnolle, N.4
-
25
-
-
0034747981
-
"Roles of cyclooxygenase isoforms in gastric mucosal defense"
-
B.M. Peskar: "Roles of cyclooxygenase isoforms in gastric mucosal defense", Journal of Physiology (Paris), Vol. 95, (2001), pp. 3-9.
-
(2001)
Journal of Physiology (Paris)
, vol.95
, pp. 3-9
-
-
Peskar, B.M.1
-
26
-
-
0034105218
-
"Effect of regulated expression of human cyclooxygenase isoform on eicosanoid and isocicosanoid production in inflammation"
-
B.F. Mc Adam, I.A. Mardini, A. Habib, A. Burke, J.A. Lawson, S. Kapoor and G.A. Fitz Gerald: "Effect of regulated expression of human cyclooxygenase isoform on eicosanoid and isocicosanoid production in inflammation", J. Clin. Invest., Vol. 105, (2000), pp. 1473-1482.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1473-1482
-
-
McAdam, B.F.1
Mardini, I.A.2
Habib, A.3
Burke, A.4
Lawson, J.A.5
Kapoor, S.6
Fitz Gerald, G.A.7
-
27
-
-
33644616789
-
"Amide derivatives for antiangiogenic and/or antitumorigenic use"
-
A.S. Kalgutkar and L.J. Marnett: "Amide derivatives for antiangiogenic and/or antitumorigenic use", Chem. Abstr., Vol. 133, (2000), 99537c.
-
(2000)
Chem. Abstr.
, vol.133
-
-
Kalgutkar, A.S.1
Marnett, L.J.2
-
28
-
-
33644613745
-
"Converting COX-inhibiting compounds to derivatives that are selective COX-2 inhibitors as non steroidal, anti-inflammatory drugs"
-
A.S. Kalgutkar and L.J. Marnett: "Converting COX-inhibiting compounds to derivatives that are selective COX-2 inhibitors as non steroidal, anti-inflammatory drugs", Chem. Abstr., Vol. 133, (2000), 99555j.
-
(2000)
Chem. Abstr.
, vol.133
-
-
Kalgutkar, A.S.1
Marnett, L.J.2
-
29
-
-
0029981646
-
"From Indomethacin to a selective COX-2 inhibitors. Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors"
-
W.C. Black, C. Bayly, M. Belley, C.C. Chan, S. Charleson, D. Denis, J.Y. Gauthier, R. Gordon, D. Guay, S. Kargman, C.K. Lau, Y. Leblanc, J. Mancini, M. Ouellet, D. Percival, P. Roy, K. Skorey, P. Tagari, P. Vickers, E. Wong, L. Xu and P. Prasit: "From Indomethacin to a selective COX-2 inhibitors. Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors", Bioorganic & Medicinal Chemistry Letters, Vol. 6, (1996), pp. 725-730.
-
(1996)
Bioorganic & Medicinal Chemistry Letters
, vol.6
, pp. 725-730
-
-
Black, W.C.1
Bayly, C.2
Belley, M.3
Chan, C.C.4
Charleson, S.5
Denis, D.6
Gauthier, J.Y.7
Gordon, R.8
Guay, D.9
Kargman, S.10
Lau, C.K.11
Leblanc, Y.12
Mancini, J.13
Ouellet, M.14
Percival, D.15
Roy, P.16
Skorey, K.17
Tagari, P.18
Vickers, P.19
Wong, E.20
Xu, I.21
Prasit, P.22
more..
-
30
-
-
0141852139
-
"Gastroduodenal tolerability of lumiracoxib vs placebo and naproxen: A pilot endoscopic study in healthy male subjects"
-
C. Rordorf, N. Kellett, S. Mair, S. Milosavljev, J. Branson and G. Scott: "Gastroduodenal tolerability of lumiracoxib vs placebo and naproxen: a pilot endoscopic study in healthy male subjects", Alimentary Pharmacology and Therapeutics, Vol. 18, (2003), pp. 533-541.
-
(2003)
Alimentary Pharmacology and Therapeutics
, vol.18
, pp. 533-541
-
-
Rordorf, C.1
Kellett, N.2
Mair, S.3
Milosavljev, S.4
Branson, J.5
Scott, G.6
-
31
-
-
9344236529
-
"Famotidine for the prevention of gastric and duodenal ulcers caused by nonsteroidal anti-inflammatory drugs"
-
A.S. Taha, N. Hudson, C.J. Hawkey, A.J. Swannell, P.N. Trye, J. Cottrell, S.G. Mass, T.J. Simon, R.D. Sturrock and R.N. Russell: "Famotidine for the prevention of gastric and duodenal ulcers caused by nonsteroidal anti-inflammatory drugs", N. Engl. J. Med., Vol. 334, (1996), pp. 1435-1439.
-
(1996)
N. Engl. J. Med.
, vol.334
, pp. 1435-1439
-
-
Taha, A.S.1
Hudson, N.2
Hawkey, C.J.3
Swannell, A.J.4
Trye, P.N.5
Cottrell, J.6
Mass, S.G.7
Simon, T.J.8
Sturrock, R.D.9
Russell, R.N.10
-
32
-
-
33644626512
-
-
(Ed): American society of hospital pharmacists Inc., Bethesda
-
G.K. Mcevoy (Ed): AHFS drug information, American society of hospital pharmacists Inc., Bethesda, 1992, pp. 1759-1763.
-
(1992)
AHFS Drug Information
, pp. 1759-1763
-
-
Mcevoy, G.K.1
-
33
-
-
33644634503
-
"Method of preventing ulcer formation caused by non steroidal anti-inflammatory drugs employing tetrazol-benzothiophene carboxamide compounds"
-
J.E. Low: "Method of preventing ulcer formation caused by non steroidal anti-inflammatory drugs employing tetrazol-benzothiophene carboxamide compounds", Chem. Abstr., Vol. 123, (1995), 102781f.
-
(1995)
Chem. Abstr.
, vol.123
-
-
Low, J.E.1
-
34
-
-
33644615594
-
"Protected forms of a conjugate combination of non-steroidal anti-inflammatory drugs (NSAIDs) and cyclooxygenase 2 (COX-2) inhibitors and their therapeutic use"
-
C.S. Lai and T.M. Wang: "Protected forms of a conjugate combination of non-steroidal anti-inflammatory drugs (NSAIDs) and cyclooxygenase 2 (COX-2) inhibitors and their therapeutic use", Chem. Abstr., Vol. 136, (2002), 15235f.
-
(2002)
Chem. Abstr.
, vol.136
-
-
Lai, C.S.1
Wang, T.M.2
-
35
-
-
33644634919
-
"Analgesic and anti-inflammatory compositions containing COX-2 inhibitors"
-
S.A. Cooper: "Analgesic and anti-inflammatory compositions containing COX-2 inhibitors", Chem. Abstr., Vol. 136, (2002), 42872t.
-
(2002)
Chem. Abstr.
, vol.136
-
-
Cooper, S.A.1
-
36
-
-
33644635639
-
"Treatment of inflammation and inflammation related disorders with a combination of COX-2 inhibitors and a 5-lipoxygenase inhibitor"
-
P.C. Isakson, G.D. Anderson and S.A. Gregory: "Treatment of inflammation and inflammation related disorders with a combination of COX-2 inhibitors and a 5-lipoxygenase inhibitor", Chem. Abstr., Vol. 133, (2000), 321880n.
-
(2000)
Chem. Abstr.
, vol.133
-
-
Isakson, P.C.1
Anderson, G.D.2
Gregory, S.A.3
-
37
-
-
0035105126
-
5-di-substituted 3-methyl-1H-pyrazolo[3,4-c] pyridazines"
-
5-di-substituted 3-methyl-1H-pyrazolo[3,4-c] pyridazines", Bioorg. Med. Chem., Vol. 9, (2001), pp. 715-718.
-
(2001)
Bioorg. Med. Chem.
, vol.9
, pp. 715-718
-
-
Tiwari, A.K.1
Mishra, A.2
-
38
-
-
0342862399
-
"Pyrazine and quinoxaline derivatives and their use as antiulcer agents"
-
T. Niho, I. Yamamoto, H. Mochizuki, I. Kimura, A. Imai and T. Nakase: "Pyrazine and quinoxaline derivatives and their use as antiulcer agents", Chem. Abstr., Vol. 124, (1996), 202307v.
-
(1996)
Chem. Abstr.
, vol.124
-
-
Niho, T.1
Yamamoto, I.2
Mochizuki, H.3
Kimura, I.4
Imai, A.5
Nakase, T.6
-
39
-
-
56849087808
-
"Preparation of pyrazine derivatives as blood platelet aggregation inhibitors and anti-inflammatory agents"
-
M. Fujitake, N. Mikami, H. Kasukawa, Y. Suwabe and A. Ota: "Preparation of pyrazine derivatives as blood platelet aggregation inhibitors and anti-inflammatory agents", Chem. Abstr., Vol. 115, (1991), 71654v.
-
(1991)
Chem. Abstr.
, vol.115
-
-
Fujitake, M.1
Mikami, N.2
Kasukawa, H.3
Suwabe, Y.4
Ota, A.5
-
40
-
-
20144381797
-
"Preparation of pyrazinobenzothiazine derivatives and analogs for the treatment of inflammation and autoimmune disease"
-
T. Kaneko, R. Clark, N. Ohi, F. Ozaki, T. Kawahara, A. Kamada, K. Okano, H. Yokohama, K. Muramoto, T. Arai, M. Ohkuro, O. Takenaka and J. Sonoda: "Preparation of pyrazinobenzothiazine derivatives and analogs for the treatment of inflammation and autoimmune disease", Chem. Abstr., Vol. 128, (1998), 204878p.
-
(1998)
Chem. Abstr.
, vol.128
, pp. 204878
-
-
Kaneko, T.1
Clark, R.2
Ohi, N.3
Ozaki, F.4
Kawahara, T.5
Kamada, A.6
Okano, K.7
Yokohama, H.8
Muramoto, K.9
Arai, T.10
Ohkuro, M.11
Takenaka, O.12
Sonoda, J.13
-
41
-
-
33644616025
-
"Preparation of heterocyclylaminophenols as inflammation inhibitors"
-
K. Abe, F. Tafusa, J. Namikawa and Y. Manabe: "Preparation of heterocyclylaminophenols as inflammation inhibitors", Chem. Abstr., Vol. 113, (1990), 231408g.
-
(1990)
Chem. Abstr.
, vol.113
-
-
Abe, K.1
Tafusa, F.2
Namikawa, J.3
Manabe, Y.4
-
42
-
-
33644621943
-
"Novel N-(pyridine-4-yl)nitrogen heterocyclic compounds useful in the treatment of inflammatory disease"
-
T.A. Kelly and R.J. Sorcek: "Novel N-(pyridine-4-yl)nitrogen heterocyclic compounds useful in the treatment of inflammatory disease", Chem. Abstr., Vol. 134, (2001), 131536n.
-
(2001)
Chem. Abstr.
, vol.134
-
-
Kelly, T.A.1
Sorcek, R.J.2
-
43
-
-
25744437104
-
"Thienopyridine derivatives as anti-inflammatory and antiarthritis agents"
-
T. Sohda, H. Makino, A. Baba and T. Yamane: "Thienopyridine derivatives as anti-inflammatory and antiarthritis agents", Chem. Abstr., Vol. 132, (2000), 49954x.
-
(2000)
Chem. Abstr.
, vol.132
-
-
Sohda, T.1
Makino, H.2
Baba, A.3
Yamane, T.4
-
44
-
-
0027424924
-
"Synthesis and anti-inflammatory activity of 5-(1,2-dihydropyridyl)2-tetrazoleacetic acids, esters and amides"
-
E.E. Knauss and P. Kumar: "Synthesis and anti-inflammatory activity of 5-(1,2-dihydropyridyl)2-tetrazoleacetic acids, esters and amides", Eur. J. Med. Chem., Vol. 28, (1993), pp. 881-885.
-
(1993)
Eur. J. Med. Chem.
, vol.28
, pp. 881-885
-
-
Knauss, E.E.1
Kumar, P.2
-
45
-
-
0008054346
-
"4,5-Substituted imidazolyl compounds for the treatment of inflammation"
-
R.M. Weier, P.W. Collins, M.A. Stealey, T.A. Barta and R.M. Huff: "4,5-Substituted imidazolyl compounds for the treatment of inflammation", Chem. Abstr., Vol. 125, (1996), 33647u.
-
(1996)
Chem. Abstr.
, vol.125
-
-
Weier, R.M.1
Collins, P.W.2
Stealey, M.A.3
Barta, T.A.4
Huff, R.M.5
-
46
-
-
3242781924
-
"1,2-Substituted imidazolyl compounds for the treatment of inflammation"
-
I.K. Khanna, R.M. Weier, P.W. Collins, Y.Yu, X. Xu, R.M. Huff, R.A. Partis and F.J. Koszyk: "1,2-Substituted imidazolyl compounds for the treatment of inflammation", Chem. Abstr., Vol. 125, (1996), 33646t.
-
(1996)
Chem. Abstr.
, vol.125
-
-
Khanna, I.K.1
Weier, R.M.2
Collins, P.W.3
Xu, Y.Yu.X.4
Huff, R.M.5
Partis, R.A.6
Koszyk, F.J.7
-
47
-
-
33644621279
-
"Benzimidazole derivatives as asthma inhibitors and compositions containing benzimidazole derivatives"
-
H. Yamada, T. Sugai, N. Kinoshita, Y. Goto, T. Sawara, N. Sueda, M. Yanai and K. Yamada: "Benzimidazole derivatives as asthma inhibitors and compositions containing benzimidazole derivatives", Chem. Abstr., Vol. 126, (1997), 282801f.
-
(1997)
Chem. Abstr.
, vol.126
-
-
Yamada, H.1
Sugai, T.2
Kinoshita, N.3
Goto, Y.4
Sawara, T.5
Sueda, N.6
Yanai, M.7
Yamada, K.8
-
48
-
-
33644624744
-
"Preparation of 2-(pyridine-2-yl methyl sulfinyl)-benziidazoles as gastric acid secretion inhibitors"
-
A.E. Braendstroem, P.L. Lindberg and G.E. Sunden: "Preparation of 2-(pyridine-2-yl methyl sulfinyl)-benziidazoles as gastric acid secretion inhibitors", Chem. Abstr., Vol. 116, (1992), 174146f.
-
(1992)
Chem. Abstr.
, vol.116
-
-
Braendstroem, A.E.1
Lindberg, P.L.2
Sunden, G.E.3
-
49
-
-
56849113976
-
"Preparation of aminopyridine derivatives as inflammation inhibitors"
-
T. Saito, N. Kawabe, T. Tanaka, E. Oomori and Y. Morya: "Preparation of aminopyridine derivatives as inflammation inhibitors", Chem. Abstr., Vol. 126, (1997), 89267h.
-
(1997)
Chem. Abstr.
, vol.126
-
-
Saito, T.1
Kawabe, N.2
Tanaka, T.3
Oomori, E.4
Morya, Y.5
-
50
-
-
33644628219
-
"Preparation of 3-sulfonamidopyridine derivatives as anti-inflammatory antipyretic and antiallergy agents"
-
Y. Yoshikawa, H. Saito, Y. Ochi and K. Hatayama: "Preparation of 3-sulfonamidopyridine derivatives as anti-inflammatory antipyretic and antiallergy agents", Chem. Abstr., Vol. 119, (1993), 117119n.
-
(1993)
Chem. Abstr.
, vol.119
-
-
Yoshikawa, Y.1
Saito, H.2
Ochi, Y.3
Hatayama, K.4
-
51
-
-
33644625005
-
"Preapartion of nitrosulfonamidopyridine derivatives as anti-inflammatory antipyretic and analgesic"
-
K. Yoshikawa, M. Hasegawa, M. Suzuki, Y. Shimazaki, M. Ohtani, S. Saito and M. Goi: "Preapartion of nitrosulfonamidopyridine derivatives as anti-inflammatory antipyretic and analgesic", Chem. Abstr., Vol. 128, (1998), 61428d.
-
(1998)
Chem. Abstr.
, vol.128
-
-
Yoshikawa, K.1
Hasegawa, M.2
Suzuki, M.3
Shimazaki, Y.4
Ohtani, M.5
Saito, S.6
Goi, M.7
-
52
-
-
0035090159
-
"Synthesis of N-pyridinyl (methyl)-1,2-dihydro-4-hydroxy-2-oxoquinoline-3-carboxamides and analogs and their anti-inflammatory activity in mice and rats"
-
X. Collins, J.M. Robert, M. Duflos, G. Wielgosz, B.G. Le, C. Robin-Dubigenon, N. Grimaud, F. Lang and J.Y. Petit: "Synthesis of N-pyridinyl (methyl)-1,2-dihydro-4-hydroxy-2-oxoquinoline-3-carboxamides and analogs and their anti-inflammatory activity in mice and rats", J. Pharm. Pharmacol., Vol. 53, (2001), pp. 417-423.
-
(2001)
J. Pharm. Pharmacol.
, vol.53
, pp. 417-423
-
-
Collins, X.1
Robert, J.M.2
Duflos, M.3
Wielgosz, G.4
Le, B.G.5
Robin-Dubigenon, C.6
Grimaud, N.7
Lang, F.8
Petit, J.Y.9
-
53
-
-
25844501422
-
"Preparation of aryl substituted pyridines, pyrimidines, pyrazines and triazines with anticonsulsant and sodium channel blocking activity"
-
D.J. Hogenkamp, P. Nguyen and B. Shao: "Preparation of aryl substituted pyridines, pyrimidines, pyrazines and triazines with anticonsulsant and sodium channel blocking activity", Chem. Abstr., Vol. 135, (2001), 257270k.
-
(2001)
Chem. Abstr.
, vol.135
-
-
Hogenkamp, D.J.1
Nguyen, P.2
Shao, B.3
-
54
-
-
25744449267
-
"Preparation of substituted pyrimidine derivatives as analgesics and anti-inflammatory agents"
-
Shibata and H. Sakatani: "Preparation of substituted pyrimidine derivatives as analgesics and anti-inflammatory agents", Chem. Abstr., Vol. 122, (1995), 290883s.
-
(1995)
Chem. Abstr.
, vol.122
-
-
Shibata1
Sakatani, H.2
-
55
-
-
0034414509
-
"Environmentally desirable synthesis without the use of organic solvent: Synthesis of 6-aryl-2 [(carboxymethyl)thio]-5-cyanopyrimidin-4(3H) one"
-
S. Paul, M. Gupta and R. Gupta: "Environmentally desirable synthesis without the use of organic solvent: Synthesis of 6-aryl-2 [(carboxymethyl)thio]-5-cyanopyrimidin-4(3H) one", Indian J. Heterocyclic Chem., Vol. 9, (2000), pp. 313-314.
-
(2000)
Indian J. Heterocyclic Chem.
, vol.9
, pp. 313-314
-
-
Paul, S.1
Gupta, M.2
Gupta, R.3
-
56
-
-
33644623653
-
"Preparation of pyrimidinediones and thioxopyrimidinones as P2-purinoceptor 7-transmembrane (TM) G-protein coupled receptor antagonists"
-
N. Kinton, P. Meghani and S. Thom: "Preparation of pyrimidinediones and thioxopyrimidinones as P2-purinoceptor 7-transmembrane (TM) G-protein coupled receptor antagonists", Chem. Abstr., Vol. 131, (1999), 19017f.
-
(1999)
Chem. Abstr.
, vol.131
-
-
Kinton, N.1
Meghani, P.2
Thom, S.3
-
57
-
-
25844434725
-
"Preparation of novel pyrimidine derivatives as gastric acid secretion inhibitors"
-
J.W. Lee, B.Y. Lee, C.S. Kim, S.K. Lee and S.J. Lee: "Preparation of novel pyrimidine derivatives as gastric acid secretion inhibitors", Chem. Abstr., Vol. 132, (2000), 347584h.
-
(2000)
Chem. Abstr.
, vol.132
-
-
Lee, J.W.1
Lee, B.Y.2
Kim, C.S.3
Lee, S.K.4
Lee, S.J.5
-
58
-
-
33644616024
-
"Preparation of hydroxyalkyl ammonium-pyrimidines or purines and nucleoside derivatives, useful as inhibitors of inflammatory cytokines"
-
B.J. Benson, X. Chen, G.J. Cianciolo, J. Diaz, K.S. Ishaq, S.L. Morris-Natschke, R.J. Uhing and H. Wong: "Preparation of hydroxyalkyl ammonium-pyrimidines or purines and nucleoside derivatives, useful as inhibitors of inflammatory cytokines", Chem. Abstr., Vol. 124, (1996), 261623t.
-
(1996)
Chem. Abstr.
, vol.124
-
-
Benson, B.J.1
Chen, X.2
Cianciolo, G.J.3
Diaz, J.4
Ishaq, K.S.5
Morris-Natschke, S.L.6
Uhing, R.J.7
Wong, H.8
-
59
-
-
0011396882
-
"Synthesis and anti-inflammatory activity of 4,6-diphenyl-2-pyrimidine carboxylic acid amides"
-
G. Myakushkene, E. Udrenaite, P. Gaidyalis and P. Vainilavichyus: "Synthesis and anti-inflammatory activity of 4,6-diphenyl-2-pyrimidine carboxylic acid amides", Pharm. Chem. J., Vol. 33, (1999), pp. 24-26.
-
(1999)
Pharm. Chem. J.
, vol.33
, pp. 24-26
-
-
Myakushkene, G.1
Udrenaite, E.2
Gaidyalis, P.3
Vainilavichyus, P.4
-
60
-
-
0006151472
-
"Synthesis and anti-inflammatory activity of 4-substituted-2-isopropylthiopyrimidines"
-
P.J. Vainilavichyus, V. Yu. Syadyaryavichyute, P.G. Gaidyalis and L.F. Gumbaragite: "Synthesis and anti-inflammatory activity of 4-substituted-2-isopropylthiopyrimidines", Khim-Farm. Zh., Vol. 27, (1993), pp. 17-19.
-
(1993)
Khim-Farm. Zh.
, vol.27
, pp. 17-19
-
-
Vainilavichyus, P.J.1
Syadyaryavichyute, V.Yu.2
Gaidyalis, P.G.3
Gumbaragite, L.F.4
-
61
-
-
0027946480
-
"5-Substituted-2,3-dihydro-6-mercapto-1,3-diphenyl- 2-thioxo-4(3H)-pyrimidinones and their 6-(acylthio)derivatives with platelet antiaggregating anti-inflammatory, antiarrhythmic, antihyperlipidemic and other activities"
-
A. Ranise, O. Bruno, F. Bondavalli, S. Schenone, M. D'Amico, M. Falciani, W. Filippelli and F. Rossi: "5-Substituted-2,3-dihydro-6-mercapto-1,3-diphenyl- 2-thioxo-4(3H)-pyrimidinones and their 6-(acylthio)derivatives with platelet antiaggregating anti-inflammatory, antiarrhythmic, antihyperlipidemic and other activities", Farmaco, Vol. 49, (1994), pp. 551-558.
-
(1994)
Farmaco
, vol.49
, pp. 551-558
-
-
Ranise, A.1
Bruno, O.2
Bondavalli, F.3
Schenone, S.4
D'Amico, M.5
Falciani, M.6
Filippelli, W.7
Rossi, F.8
-
62
-
-
2542642890
-
"Reactions of 4-isothiocyanato-4-methyl-2-pentanone with amines having functional groups at β position and anti-inflammatory evaluation of resulting heterocyclic compounds"
-
R.K. Sahu, A. Magan, B.Gupta, S.M. Sondhi, R.C. Srimal and G.K. Patnaik: "Reactions of 4-isothiocyanato-4-methyl-2-pentanone with amines having functional groups at β position and anti-inflammatory evaluation of resulting heterocyclic compounds", Phosphorus, Sulfur and Silicon, Vol. 88, (1994), pp. 45-51.
-
(1994)
Phosphorus, Sulfur and Silicon
, vol.88
, pp. 45-51
-
-
Sahu, R.K.1
Magan, A.2
Gupta, B.3
Sondhi, S.M.4
Srimal, R.C.5
Patnaik, G.K.6
-
63
-
-
0032958607
-
"Antiinflammatory and analgesic activity evaluation of some thiocarbamate thiourea, bisthiourea, acridine acridone and pyrimidine derivatives"
-
S.M. Sondhi, R.P. Verma, N. Singhal, R. Shukla, R. Raghubir and M.P. Dubey: "Antiinflammatory and analgesic activity evaluation of some thiocarbamate thiourea, bisthiourea, acridine acridone and pyrimidine derivatives", Indian Drugs, Vol. 36, (1999), pp. 50-54.
-
(1999)
Indian Drugs
, vol.36
, pp. 50-54
-
-
Sondhi, S.M.1
Verma, R.P.2
Singhal, N.3
Shukla, R.4
Raghubir, R.5
Dubey, M.P.6
-
64
-
-
0034416593
-
"Synthesis and anticancer, anti-inflammatory and analgesic activity evaluation of some sulpha drug and acridine derivatives"
-
S.M. Sondhi, M. Johar, N. Singhal, S.G. Dastidar, R. Shukla and R. Raghubir: "Synthesis and anticancer, anti-inflammatory and analgesic activity evaluation of some sulpha drug and acridine derivatives", Monatsh Chem., Vol. 131, (2000), pp. 511-520.
-
(2000)
Monatsh Chem.
, vol.131
, pp. 511-520
-
-
Sondhi, S.M.1
Johar, M.2
Singhal, N.3
Dastidar, S.G.4
Shukla, R.5
Raghubir, R.6
-
65
-
-
0027971496
-
"Evaluation of some anti-inflammatory pyrimidobenzimidazoles synthesized via Noval Tin (II) Chloride-Hydrochloride acid assisted water addition and reduction of 4,4,6-trimethyl-1(2-nitroaryl)-1,4-dihydropyrimidine-2(3H)-thiones"
-
S.M. Sondhi, A. Magan, R.K. Sahu, V.K. Mahesh, R. Shukla and G.K. Patnaik: "Evaluation of some anti-inflammatory pyrimidobenzimidazoles synthesized via Noval Tin (II) Chloride-Hydrochloride acid assisted water addition and reduction of 4,4,6-trimethyl-1(2-nitroaryl)-1,4-dihydropyrimidine-2(3H)-thiones", Synthesis, Vol. 11, (1994), pp. 1175-1180.
-
(1994)
Synthesis
, vol.11
, pp. 1175-1180
-
-
Sondhi, S.M.1
Magan, A.2
Sahu, R.K.3
Mahesh, V.K.4
Shukla, R.5
Patnaik, G.K.6
-
66
-
-
0032914875
-
"Synthesis, anti-inflammatory and analgesic activity evaluation of some mercaptopyrimidine and pyrimidobenzimidazole derivatives"
-
S.M. Sondhi, V.K. Sharma, R.P. Verma, N. Singhal, R. Shukla, R. Raghubir and M.P. Dubey: "Synthesis, anti-inflammatory and analgesic activity evaluation of some mercaptopyrimidine and pyrimidobenzimidazole derivatives", Synthesis, Vol. 5, (1999), pp. 878-884.
-
(1999)
Synthesis
, vol.5
, pp. 878-884
-
-
Sondhi, S.M.1
Sharma, V.K.2
Verma, R.P.3
Singhal, N.4
Shukla, R.5
Raghubir, R.6
Dubey, M.P.7
-
67
-
-
0001803432
-
"Antiinflammatory and analgesic activity evaluation of heterocyclic compounds synthesized by the reaction of 4-isothiocyanato-4-methyl-2-pentanone with amines"
-
S.M. Sondhi, R.P. Verma, N. Singhal, V.K. Sharma, R. Shukla and G.K. Patnaik: "Antiinflammatory and analgesic activity evaluation of heterocyclic compounds synthesized by the reaction of 4-isothiocyanato-4-methyl-2-pentanone with amines", Phosphorus Sulphur & Silicon, Vol. 118, (1996), pp. 7-19.
-
(1996)
Phosphorus Sulphur & Silicon
, vol.118
, pp. 7-19
-
-
Sondhi, S.M.1
Verma, R.P.2
Singhal, N.3
Sharma, V.K.4
Shukla, R.5
Patnaik, G.K.6
-
68
-
-
0034953878
-
"Anticancer, anti-inflammatory and analgesic activity evaluation of heterocyclic compounds synthesized by the reaction of 4-isothiothiocyanato-4-methylpentan-2-one with substituted o-phenylenediamines, o-diaminopyridine and (un) substituted o-diaminopyrimidines"
-
S.M. Sondhi, M. Johar, S. Rajvanshi, S.G. Dastidar, R. Shukla, R. Raghubir and J.W. Lown: "Anticancer, anti-inflammatory and analgesic activity evaluation of heterocyclic compounds synthesized by the reaction of 4-isothiothiocyanato-4-methylpentan-2-one with substituted o-phenylenediamines, o-diaminopyridine and (un) substituted o-diaminopyrimidines", Aust. J. Chem., Vol. 54, (2001), pp. 69-74.
-
(2001)
Aust. J. Chem.
, vol.54
, pp. 69-74
-
-
Sondhi, S.M.1
Johar, M.2
Rajvanshi, S.3
Dastidar, S.G.4
Shukla, R.5
Raghubir, R.6
Lown, J.W.7
-
69
-
-
0001427836
-
"Synthesis and anti-inflammatory and anticancer activity evaluation of some condensed pyrimidines"
-
S.M. Sondhi, N. Singhal, R.P. Verma, S.K. Arora, R. Shukla and R. Raghubir: "Synthesis and anti-inflammatory and anticancer activity evaluation of some condensed pyrimidines", Monatsh Chem., Vol. 131, (2000), pp. 501-509.
-
(2000)
Monatsh Chem.
, vol.131
, pp. 501-509
-
-
Sondhi, S.M.1
Singhal, N.2
Verma, R.P.3
Arora, S.K.4
Shukla, R.5
Raghubir, R.6
-
70
-
-
0013246573
-
"Synthesis, anti-inflammatory, analgesic and antiamoebic activity evaluation of some pyrimidobenzimidazole and pyrimidopyridoimidazole derivatives"
-
S.M. Sondhi, M. Johar, R. Shukla, R. Raghubir, N. Bharti and A. Azam: "Synthesis, anti-inflammatory, analgesic and antiamoebic activity evaluation of some pyrimidobenzimidazole and pyrimidopyridoimidazole derivatives", Aust. J. Chem., Vol. 54, (2001), pp. 461-467.
-
(2001)
Aust. J. Chem.
, vol.54
, pp. 461-467
-
-
Sondhi, S.M.1
Johar, M.2
Shukla, R.3
Raghubir, R.4
Bharti, N.5
Azam, A.6
-
71
-
-
0036809043
-
"Antiinflammatory, analgesic and antiamoebic activity evaluation of pyrimido [1,6-a] benzimidazole derivatives synthesized by the reaction of ketoisothiocyanates with mono and diamines"
-
S.M. Sondhi, S. Rajvanshi, M. Johar, N. Bharti, A. Azam and A.K. Singh: "Antiinflammatory, analgesic and antiamoebic activity evaluation of pyrimido [1,6-a] benzimidazole derivatives synthesized by the reaction of ketoisothiocyanates with mono and diamines", Eur. J. Med. Chem., Vol. 37, (2002), pp. 835-843.
-
(2002)
Eur. J. Med. Chem.
, vol.37
, pp. 835-843
-
-
Sondhi, S.M.1
Rajvanshi, S.2
Johar, M.3
Bharti, N.4
Azam, A.5
Singh, A.K.6
-
72
-
-
33644620528
-
"Preparation of 6,7-disubstituted 4-aminopyrido [2,3-d] pyrimidines as adenosine kinase inhibitors"
-
S.S. Bhagwat, C.H. Lee, R.J. Perner and Y.C. Gu: "Preparation of 6,7-disubstituted 4-aminopyrido [2,3-d] pyrimidines as adenosine kinase inhibitors", Chem. Abstr., Vol. 135, (2001), P152822p.
-
(2001)
Chem. Abstr.
, vol.135
-
-
Bhagwat, S.S.1
Lee, C.H.2
Perner, R.J.3
Gu, Y.C.4
-
73
-
-
0034975709
-
"Effect of imidazo [1,2-a] pyrimidine derivatives on leukocyte fuction"
-
A. Vidal, M.L. Ferrandiz, A. Ubeda, A. Acero-Alarcon, J. Sepulveda-Arques and M.J. Alcaraz: "Effect of imidazo [1,2-a] pyrimidine derivatives on leukocyte fuction", Inflammation Res., Vol. 50, (2001), pp. 317-320.
-
(2001)
Inflammation Res.
, vol.50
, pp. 317-320
-
-
Vidal, A.1
Ferrandiz, M.L.2
Ubeda, A.3
Acero-Alarcon, A.4
Sepulveda-Arques, J.5
Alcaraz, M.J.6
-
74
-
-
0032033113
-
"Research on heterocyclic compounds-Part XXXIX. 2-Methylimidazo [1,2-a] pyrimidine-3-caroboxylic derivatives: Synthesis and anti-inflammatory activity"
-
S. Laneri, A. Sacchi, M. Gallitelli, F. Arena, E. Lurachi, E. Abignente, W. Filippelli and F. Rossi: "Research on heterocyclic compounds-Part XXXIX. 2-Methylimidazo [1,2-a] pyrimidine-3-caroboxylic derivatives:Synthesis and anti-inflammatory activity", Eur. J. Med. Chem., Vol. 33, (1998), pp. 163-170.
-
(1998)
Eur. J. Med. Chem.
, vol.33
, pp. 163-170
-
-
Laneri, S.1
Sacchi, A.2
Gallitelli, M.3
Arena, F.4
Lurachi, E.5
Abignente, E.6
Filippelli, W.7
Rossi, F.8
-
75
-
-
0033505698
-
"Synthesis of novel 1,2-(un) substituted-3-amino-5-aryl-6-arylaminopyrazolo [3,4-d] pyrimidin-4(5H) ones and their biological activities"
-
C.J. Shishoo, T. Ravikumar, K.S. Jain, I.S. Rathod, T.P. Gandhi, M.C. Satia: "Synthesis of novel 1,2-(un) substituted-3-amino-5-aryl-6-arylaminopyrazolo [3,4-d] pyrimidin-4(5H) ones and their biological activities", Indian J. Chem. Sec. B., Vol. 38, (1999), pp. 1075-1085.
-
(1999)
Indian J. Chem. Sec. B.
, vol.38
, pp. 1075-1085
-
-
Shishoo, C.J.1
Ravikumar, T.2
Jain, K.S.3
Rathod, I.S.4
Gandhi, T.P.5
Satia, M.C.6
-
76
-
-
4243487644
-
"Prepartion of pyrazolo [1,5-a] pyrimidine derivatives as analgesics"
-
M. Inoe, Y. Shoji, T. Okamura, K. Hashimoto, M. Obara and T. Yasuda: "Prepartion of pyrazolo [1,5-a] pyrimidine derivatives as analgesics", Chem. Abstr., Vol. 124, (1996), 317190u.
-
(1996)
Chem. Abstr.
, vol.124
-
-
Inoe, M.1
Shoji, Y.2
Okamura, T.3
Hashimoto, K.4
Obara, M.5
Yasuda, T.6
-
77
-
-
0032887950
-
"Synthesis and pharmacological evaluation of some novel 5-aryl-6-arylamine-1-phenylpyrazolo [3,4-d] pyrimidin-4(5H)-ones as analgesic and anti-inflammatory agents
-
C.J. Shishoo, U.S. Pathak, I.S. Rathod, K.S. Jain, C.G. Nargund, A.D. Taranalli, H. Patel, V. Kumar and V.S. Shirsath: "Synthesis and pharmacological evaluation of some novel 5-aryl-6-arylamine-1-phenylpyrazolo [3,4-d] pyrimidin-4(5H)-ones as analgesic and anti-inflammatory agents, Indian J. Chem. Sec. B., Vol. 38, (1999), pp. 684-695.
-
(1999)
Indian J. Chem. Sec. B.
, vol.38
, pp. 684-695
-
-
Shishoo, C.J.1
Pathak, U.S.2
Rathod, I.S.3
Jain, K.S.4
Nargund, C.G.5
Taranalli, A.D.6
Patel, H.7
Kumar, V.8
Shirsath, V.S.9
-
78
-
-
0031847745
-
"Condensed heterocyclic compounds: Synthesis and anti-inflammatory activity of novel thiazolo [3,2-a] pyrimidines"
-
B. Tozkoparan, M. Ertan, B. Krebs, M. Laegs, P. Kelicen and R. Demirdamar: "Condensed heterocyclic compounds: Synthesis and anti-inflammatory activity of novel thiazolo [3,2-a] pyrimidines", Arch. Pharm., Vol. 331, (1998), pp. 201-206.
-
(1998)
Arch. Pharm.
, vol.331
, pp. 201-206
-
-
Tozkoparan, B.1
Ertan, M.2
Krebs, B.3
Laegs, M.4
Kelicen, P.5
Demirdamar, R.6
-
79
-
-
0032825505
-
"Synthesis and anti-inflammatory activity of some thiazolo [3,2-a] pyrimidines derivatives"
-
B. Tozkoparan, M. Ertan, P. Kelicen and R. Demirdamar: "Synthesis and anti-inflammatory activity of some thiazolo [3,2-a] pyrimidines derivatives", Farmaco, Vol. 54, (1999), pp. 588-593.
-
(1999)
Farmaco
, vol.54
, pp. 588-593
-
-
Tozkoparan, B.1
Ertan, M.2
Kelicen, P.3
Demirdamar, R.4
-
80
-
-
33644629556
-
"Preparation of 5,7-disubstituted-4-aminopyrido [2,3-d] pyrimidines as adenosine kinase inhibitors"
-
S.S. Bhagwat, C.H. Lee, M.D. Cowart, J.A. Mckie, A.L. Grillot, A.O. Stewart, G.Z. Zheng and R.J. Perner: "Preparation of 5,7-disubstituted-4-aminopyrido [2,3-d] pyrimidines as adenosine kinase inhibitors", Chem. Abstr., Vol. 132, (2000), 308351k.
-
(2000)
Chem. Abstr.
, vol.132
-
-
Bhagwat, S.S.1
Lee, C.H.2
Cowart, M.D.3
Mckie, J.A.4
Grillot, A.L.5
Stewart, A.O.6
Zheng, G.Z.7
Perner, R.J.8
-
81
-
-
0035866588
-
"Solid phase synthesis and inhibitory effects of some pyrido [1,2-c] pyrimidine derivatives on leukocyte functions and experimental inflammation"
-
P. Molina, E. Aller, A. Lorenzo, P. Lopez-Cremades, I.U.A. Rioja, M.C. Terencio and M.J. Alcaraz: "Solid phase synthesis and inhibitory effects of some pyrido [1,2-c] pyrimidine derivatives on leukocyte functions and experimental inflammation", J. Med. Chem., Vol. 44, (2001), pp. 1011-1014.
-
(2001)
J. Med. Chem.
, vol.44
, pp. 1011-1014
-
-
Molina, P.1
Aller, E.2
Lorenzo, A.3
Lopez-Cremades, P.4
Rioja, I.U.A.5
Terencio, M.C.6
Alcaraz, M.J.7
-
82
-
-
0345685628
-
"A pyrimidine derivative for treatment of inflammatory bowel diseases"
-
S. Oomura, N. Takenawa and S. Kamya: "A pyrimidine derivative for treatment of inflammatory bowel diseases", Chem. Abstr., Vol. 123, (1995), 965b.
-
(1995)
Chem. Abstr.
, vol.123
-
-
Oomura, S.1
Takenawa, N.2
Kamya, S.3
-
83
-
-
0026399079
-
"Research on heterocyclic compounds XXVIII. Imidazo [1,2-c] pyrimidines"
-
E. Abignente, F. Arena, P. de Caprariis, E. Luraschi, A. Sacchi, E. Lampa, L. Berrino and D. Donnoli: "Research on heterocyclic compounds XXVIII. Imidazo [1,2-c] pyrimidines", Farmaco, Vol. 46, (1991), pp. 1099-1110.
-
(1991)
Farmaco
, vol.46
, pp. 1099-1110
-
-
Abignente, E.1
Arena, F.2
de Caprariis, P.3
Luraschi, E.4
Sacchi, A.5
Lampa, E.6
Berrino, L.7
Donnoli, D.8
-
84
-
-
0028220833
-
"Research on heterocyclic compounds XXVII. Synthesis and Cyclooxygenase-indipendent anti-inflammatory and analgesic activity of imidazo-[1,2-a] pyrimidine derivatives"
-
E. Abignente, A. Sacchi, S. Laneri, F. Rossi, M. D'Amico, L. Berrino, V. Calderaro and C. Parrillo: "Research on heterocyclic compounds XXVII. Synthesis and Cyclooxygenase-indipendent anti-inflammatory and analgesic activity of imidazo-[1,2-a] pyrimidine derivatives", Eur. J. Med. Chem., Vol. 29, (1994), pp. 279-286.
-
(1994)
Eur. J. Med. Chem.
, vol.29
, pp. 279-286
-
-
Abignente, E.1
Sacchi, A.2
Laneri, S.3
Rossi, F.4
D'Amico, M.5
Berrino, L.6
Calderaro, V.7
Parrillo, C.8
-
85
-
-
0029561836
-
"Synthesis and pharmacological evaluation of thieno [2,3-d] pyrimidine-2,4-dione and 5H pyrimido [5,4]indole-2,4-dione derivatives"
-
N.A. Santagati, A. Caruso, V.M.C. Cutuli and F. Caccamo: "Synthesis and pharmacological evaluation of thieno [2,3-d] pyrimidine-2,4-dione and 5H pyrimido [5,4]indole-2,4-dione derivatives", Farmaco, Vol. 50, (1995), pp. 689-695.
-
(1995)
Farmaco
, vol.50
, pp. 689-695
-
-
Santagati, N.A.1
Caruso, A.2
Cutuli, V.M.C.3
Caccamo, F.4
-
86
-
-
0031884959
-
"Synthesis of new thieno [2,3-d] pyrimidine-2,4-[1H,3H]diones with analgesic and anti-inflammatory activities"
-
G. Romeo, F. Russo, A. Caruso, V. Cutuli and M. Amico-Roxas: "Synthesis of new thieno [2,3-d] pyrimidine-2,4-[1H,3H]diones with analgesic and anti-inflammatory activities", Arzneim-Forsch, Vol. 48, (1998), pp. 167-172.
-
(1998)
Arzneim-Forsch
, vol.48
, pp. 167-172
-
-
Romeo, G.1
Russo, F.2
Caruso, A.3
Cutuli, V.4
Amico-Roxas, M.5
-
87
-
-
0029807271
-
"Synthesis and pharmaceuticals study of new 3,4-dihydro-2H,6H-pyrimido [2,1-b] [1,3] thiazines"
-
D. Bozsing, P. Sohar, G. Gigler and G. Kovacs: "Synthesis and pharmaceuticals study of new 3,4-dihydro-2H,6H-pyrimido [2,1-b] [1,3] thiazines", Eur J. Med. Chem., Vol. 31, (1996), pp. 663-668.
-
(1996)
Eur J. Med. Chem.
, vol.31
, pp. 663-668
-
-
Bozsing, D.1
Sohar, P.2
Gigler, G.3
Kovacs, G.4
-
88
-
-
33644610994
-
"Preparation of pyrimidine fused compounds as antiallergic and anti-inflammatory agents"
-
J. Bantick, M. Perry and P. Thorne: "Preparation of pyrimidine fused compounds as antiallergic and anti-inflammatory agents", Chem. Abstr., Vol. 128, (1998), 140714x.
-
(1998)
Chem. Abstr.
, vol.128
-
-
Bantick, J.1
Perry, M.2
Thorne, P.3
-
89
-
-
0023617438
-
"Synthesis and biological activity of acridinyl-9-thioacetic acids and their derivatives"
-
A.N. Gaidukevich, G.P. Kazakov, A.A. Kravchenko, L.A. Porokhnyak, V.V. Pinchuk and D.L. Velikii: "Synthesis and biological activity of acridinyl-9-thioacetic acids and their derivatives", Khim. Pharm. Zh., Vol. 21, (1987), pp. 1067-1070.
-
(1987)
Khim. Pharm. Zh.
, vol.21
, pp. 1067-1070
-
-
Gaidukevich, A.N.1
Kazakov, G.P.2
Kravchenko, A.A.3
Porokhnyak, L.A.4
Pinchuk, V.V.5
Velikii, D.L.6
-
90
-
-
0025317890
-
"Synthesis and structure activity relationships of anti-inflammatory 9,10-dihydro-9-oxo-2-acridinealkanoic acids and 4-(2-carboxyphenyl)amino benzene alkanoic acids"
-
I.B. Taraporewala and J.M. Kauffman: "Synthesis and structure activity relationships of anti-inflammatory 9,10-dihydro-9-oxo-2-acridinealkanoic acids and 4-(2-carboxyphenyl)amino benzene alkanoic acids", J. Pharm. Sci., Vol. 79, (1990), pp. 173-178.
-
(1990)
J. Pharm. Sci.
, vol.79
, pp. 173-178
-
-
Taraporewala, I.B.1
Kauffman, J.M.2
-
91
-
-
4244075580
-
"Substituted bisacridines and related compounds as CCR5 receptor ligands, anti-inflammatory agents and antiviral Agents"
-
W.E. Bondinell, Y.A. Reader and T.W.F. Ku: "Substituted bisacridines and related compounds as CCR5 receptor ligands, anti-inflammatory agents and antiviral Agents", Chem. Abstr., Vol. 129, (1998), 122582u.
-
(1998)
Chem. Abstr.
, vol.129
-
-
Bondinell, W.E.1
Reader, Y.A.2
Ku, T.W.F.3
-
92
-
-
0000951043
-
"Syntheis, anti-inflammatory and analgesic activity evaluation of some 2-(9-acridinylamino)pyridines and 2-(9-acridinylamino/imino)thiazolines"
-
S.M. Sondhi, N. Singhal, R.P. Verma, R. Raghubir, A.K. Goel and G.K. Patnaik: "Syntheis, anti-inflammatory and analgesic activity evaluation of some 2-(9-acridinylamino)pyridines and 2-(9-acridinylamino/imino)thiazolines", Indian J. Chem. Sec. B., Vol. 36, (1997), pp. 620-624.
-
(1997)
Indian J. Chem. Sec. B.
, vol.36
, pp. 620-624
-
-
Sondhi, S.M.1
Singhal, N.2
Verma, R.P.3
Raghubir, R.4
Goel, A.K.5
Patnaik, G.K.6
-
93
-
-
0034338732
-
"Synthesis and anti-inflammatory activity evaluation of some acridinyl amino antipyrine, acridinyl amino anthraquinone, acridino thiourea and thiazolino thiourea derivatives"
-
S.M. Sondhi, V.K. Sharma, N. Singhal, R.P. Verma, R. Shukla, R. Raghubir and M.P. Dubey: "Synthesis and anti-inflammatory activity evaluation of some acridinyl amino antipyrine, acridinyl amino anthraquinone, acridino thiourea and thiazolino thiourea derivatives", Phosphorus, Sulphur and Silicon, Vol. 156, (2000), pp. 21-33.
-
(2000)
Phosphorus, Sulphur and Silicon
, vol.156
, pp. 21-33
-
-
Sondhi, S.M.1
Sharma, V.K.2
Singhal, N.3
Verma, R.P.4
Shukla, R.5
Raghubir, R.6
Dubey, M.P.7
-
94
-
-
0036928133
-
"Synthesis of sulphadrug acridine derivatives and their evaluation for anti-inflammatory, analgesic and anticancer activity"
-
S.M. Sondhi, M. Johar, R. Shukla, R. Raghubir and S.G. Dastidar: "Synthesis of sulphadrug acridine derivatives and their evaluation for anti-inflammatory, analgesic and anticancer activity.", Indian J. Chem. Sec. B., Vol. 41, (2002), 2659-2666.
-
(2002)
Indian J. Chem. Sec. B.
, vol.41
, pp. 2659-2666
-
-
Sondhi, S.M.1
Johar, M.2
Shukla, R.3
Raghubir, R.4
Dastidar, S.G.5
-
95
-
-
0001103646
-
"Synthesis, isomer identification by 2D-NMR and anti-inflammatory evaluation of some 9H-imidazolo [1,2-a] benzimidazole and perhydroimidazolo [1,2-d], [1,2,4] dithiazepine derivatives"
-
S.M. Sondhi, A. Magan, V.K. Mahesh, R.C. Srimal and A.K. Goel: "Synthesis, isomer identification by 2D-NMR and anti-inflammatory evaluation of some 9H-imidazolo [1,2-a] benzimidazole and perhydroimidazolo [1,2-d], [1,2,4] dithiazepine derivatives", Indian J. Chem., Vol. 33B, (1994), pp. 1144-1149.
-
(1994)
Indian J. Chem.
, vol.33 B
, pp. 1144-1149
-
-
Sondhi, S.M.1
Magan, A.2
Mahesh, V.K.3
Srimal, R.C.4
Goel, A.K.5
-
96
-
-
0005787022
-
"Preparation of 2-substituted 4,5-diaryl imidazoloes as antiinflammatories and immunosuppressants"
-
L. Revesz: "Preparation of 2-substituted 4,5-diaryl imidazoloes as antiinflammatories and immunosuppressants", Chem. Abstr., Vol. 130, (1999), 125072j.
-
(1999)
Chem. Abstr.
, vol.130
-
-
Revesz, L.1
-
97
-
-
0034458276
-
"Synthesis and anti-inflammatory activity of some new 1-acylderivatives of 5,6-diethoxy-2-(methylthio)benzimidazole"
-
L.K. Labanauskas, A.B. Brukstus, P.G. Gaidelis, V.A. Buchinskaite, E.B. Udrenaite and V.K. Dauksas: "Synthesis and anti-inflammatory activity of some new 1-acylderivatives of 5,6-diethoxy-2-(methylthio)benzimidazole", Pharm. Chem. J., Vol. 34, (2000), pp. 353-355.
-
(2000)
Pharm. Chem. J.
, vol.34
, pp. 353-355
-
-
Labanauskas, L.K.1
Brukstus, A.B.2
Gaidelis, P.G.3
Buchinskaite, V.A.4
Udrenaite, E.B.5
Dauksas, V.K.6
-
98
-
-
33644616654
-
"Preparation of benzisothiazoles derivatives as inhibitors of 5-lipoxygenase biosynthesis"
-
J.F. Eggler: "Preparation of benzisothiazoles derivatives as inhibitors of 5-lipoxygenase biosynthesis", Chem. Abstr., Vol. 124, (1996), 117304x.
-
(1996)
Chem. Abstr.
, vol.124
-
-
Eggler, J.F.1
-
99
-
-
33644621943
-
"Novel N-(pyridin-4-yl)nitrogen heterocyclic compounds useful in the treatment of inflammatory disease"
-
T.A. Kelly and R.J. Sorcek: "Novel N-(pyridin-4-yl)nitrogen heterocyclic compounds useful in the treatment of inflammatory disease", Chem. Abstr., Vol. 134, (2001), 131536n.
-
(2001)
Chem. Abstr.
, vol.134
-
-
Kelly, T.A.1
Sorcek, R.J.2
-
100
-
-
25744437104
-
"Thienopyridine derivatives as anti-inflammatory and antiarthritis agents"
-
T. Sohda, H. Makino, A. Baba and T. Yamane: "Thienopyridine derivatives as anti-inflammatory and antiarthritis agents", Chem. Abstr., Vol. 132, (2000), 49954x.
-
(2000)
Chem. Abstr.
, vol.132
-
-
Sohda, T.1
Makino, H.2
Baba, A.3
Yamane, T.4
-
101
-
-
0035671557
-
"Cyclooxygenase-1 and cyclooxygenase-2 selectivity of non-steroidal anti-inflammatory drugs: Investigation using human peripheral monocytes"
-
M. Kato, S. Nishida, H. Kita Sato, N. Sakata and S. Kawai: "Cyclooxygenase-1 and cyclooxygenase-2 selectivity of non-steroidal anti-inflammatory drugs: investigation using human peripheral monocytes", Journal of Pharmacy and Pharmacology, Vol. 53, (2001), pp. 1679-1685.
-
(2001)
Journal of Pharmacy and Pharmacology
, vol.53
, pp. 1679-1685
-
-
Kato, M.1
Nishida, S.2
Kita Sato, H.3
Sakata, N.4
Kawai, S.5
-
102
-
-
0041407189
-
"Establishment of screening models for selective cyclooxygenase-2 inhibitors"
-
Y. Hu and G. Cheng: "Establishment of screening models for selective cyclooxygenase-2 inhibitors", Yaoxue Xuebao, Vol. 35, (2000), pp. 343-346.
-
(2000)
Yaoxue Xuebao
, vol.35
, pp. 343-346
-
-
Hu, Y.1
Cheng, G.2
-
103
-
-
0033936426
-
"In vitro effects of nonsteroidal anti-inflammatory drugs on cyclooxygenase activity in dogs"
-
P. Kay-Mugford, S.J. Bori, J. LaMarre and P. Conlon: "In vitro effects of nonsteroidal anti-inflammatory drugs on cyclooxygenase activity in dogs", Am. J. Vet. Res., Vol. 61, (2000), pp. 802-810.
-
(2000)
Am. J. Vet. Res.
, vol.61
, pp. 802-810
-
-
Kay-Mugford, P.1
Bori, S.J.2
LaMarre, J.3
Conlon, P.4
-
104
-
-
0032452709
-
"Mechanism of action of anti-inflammatory drugs"
-
J.R. Vane and R.M. Botting: "Mechanism of action of anti-inflammatory drugs", Int. J. Tissue React., Vol. 20, (1998), pp. 3-15.
-
(1998)
Int. J. Tissue React.
, vol.20
, pp. 3-15
-
-
Vane, J.R.1
Botting, R.M.2
-
105
-
-
33644632268
-
"Aryl phenyl hydrazides as selective COX-2 inhibitors for the treatment of inflammation"
-
Z. Sui and M. Wachter: "Aryl phenyl hydrazides as selective COX-2 inhibitors for the treatment of inflammation", Chem. Abstr., Vol. 133, (2000), 38226f.
-
(2000)
Chem. Abstr.
, vol.133
-
-
Sui, Z.1
Wachter, M.2
-
106
-
-
0034055550
-
"Pharmacology of selective cyclooxygenase-1 inhibitor, HN - 56249: A novel compounds exhibiting a marked preference for the human enzyme in intact cells"
-
J. Berg, H. Fellier, T. Christoph, P. Kremminger, M. Hartman, H. Blaschke, F. Rovensky, R. Towart and D. Stimmeder: "Pharmacology of selective cyclooxygenase-1 inhibitor, HN - 56249: a novel compounds exhibiting a marked preference for the human enzyme in intact cells", Naunym- Schmiedeberg's Arch. Pharmacol., Vol. 361, (2000), pp. 363-372.
-
(2000)
Naunym- Schmiedeberg's Arch. Pharmacol.
, vol.361
, pp. 363-372
-
-
Berg, J.1
Fellier, H.2
Christoph, T.3
Kremminger, P.4
Hartman, M.5
Blaschke, H.6
Rovensky, F.7
Towart, R.8
Stimmeder, D.9
-
107
-
-
0000224843
-
"Preparation of 3, 4-diphenyl- 2, 5-dihydro- 2- furanones as novel compounds having anti-inflammatory activity"
-
M. Pal, K.R. Yeleswarapu, R. Ramanujam, P. Misra, P.K. Mamnoor and S.R. Casturi: "Preparation of 3, 4-diphenyl- 2, 5-dihydro- 2- furanones as novel compounds having anti-inflammatory activity", Chem. Abstr., Vol. 136, (2000), 5893e.
-
(2000)
Chem. Abstr.
, vol.136
-
-
Pal, M.1
Yeleswarapu, K.R.2
Ramanujam, R.3
Misra, P.4
Mamnoor, P.K.5
Casturi, S.R.6
-
108
-
-
33644627432
-
"Novel imidazoles with anti-inflammatory activity and their preparation and use"
-
C. Almansa, C. Gonzalez and M.C. Torres: "Novel imidazoles with anti-inflammatory activity and their preparation and use", Chem. Abstr., 132, (2000), 308336j.
-
(2000)
Chem. Abstr.
, vol.132
-
-
Almansa, C.1
Gonzalez, C.2
Torres, M.C.3
-
109
-
-
0034632752
-
"Selective cyclooxygenase-2-inhibitors: Heteroaryl modified 1,2-diarylimidazoles are potent, orally active anti-inflammatory agents"
-
I.K. Khanna, Yi. Yu, R.M. Hur, R.M. Weier, X. Xu, F.J Koszyk, P.W. Collins, J.N. Cogburn, P.C. Isakson, C.M. Koboldt, J.L.Masferrer, W.E. Perkins, K. Seibert, A.W. Veenhuizen, J. Yuan, D.C. Yang, Y.Y. Zhang: "Selective cyclooxygenase-2-inhibitors: heteroaryl modified 1,2-diarylimidazoles are potent, orally active anti-inflammatory agents", J. Med. Chem., Vol. 43, (2000), pp. 3168-3185.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 3168-3185
-
-
Khanna, I.K.1
Yu, Yi.2
Hur, R.M.3
Weier, R.M.4
Xu, X.5
Koszyk, F.J.6
Collins, P.W.7
Cogburn, J.N.8
Isakson, P.C.9
Koboldt, C.M.10
Masferrer, J.L.11
Perkins, W.E.12
Seibert, K.13
Veenhuizen, A.W.14
Yuan, J.15
Yang, D.C.16
Zhang, Y.Y.17
-
110
-
-
34250325688
-
"Preparation of heterocycle substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors"
-
J.J. Talley, J.A. Sikorski, M.J. Graneto, J.S. Carter, B.H. Norma, B. Devadas and H.F. Lu: "Preparation of heterocycle substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors", Chem. Abstr., Vol. 136, (2002), 69808p.
-
(2002)
Chem. Abstr.
, vol.136
-
-
Talley, J.J.1
Sikorski, J.A.2
Graneto, M.J.3
Carter, J.S.4
Norma, B.H.5
Devadas, B.6
Lu, H.F.7
-
111
-
-
0037060906
-
"Synthesis and activity of a new Methoxytetra-hydropyran derivatives as duel cyclooxygenase-2/5-Lipoxygenase inhibitor"
-
S. Barkey, L. Goossens, T. Taverne, J. Cornet, V. Choesmel, C. Rouand, G. Gimeno, S. Yannic-Arnoult, C. Michaux, C. Charlier, R. Houssin and J.-P. Henichart: "Synthesis and activity of a new Methoxytetra-hydropyran derivatives as duel cyclooxygenase-2/5-Lipoxygenase inhibitor", Bioorganic & Medicinal Chemistry Letters, Vol. 12, (2002), pp. 779-782.
-
(2002)
Bioorganic & Medicinal Chemistry Letters
, vol.12
, pp. 779-782
-
-
Barkey, S.1
Goossens, L.2
Taverne, T.3
Cornet, J.4
Choesmel, V.5
Rouand, C.6
Gimeno, G.7
Yannic-Arnoult, S.8
Michaux, C.9
Charlier, C.10
Houssin, R.11
Henichart, J.-P.12
-
112
-
-
33644629978
-
"Preparation of heteroarylpyrazoles using dithietanses"
-
M.J. Graneto, S.J. Hartman, S. Metz, M.J. Talley, M.L. Vazquez, D.L. Brown, R.M. Weier, M.A. Stealey and X. Xu: "Preparation of heteroarylpyrazoles using dithietanses", Chem. Abstr., Vol. 133, (2000), 4657g.
-
(2000)
Chem. Abstr.
, vol.133
-
-
Graneto, M.J.1
Hartman, S.J.2
Metz, S.3
Talley, M.J.4
Vazquez, M.L.5
Brown, D.L.6
Weier, R.M.7
Stealey, M.A.8
Xu, X.9
-
113
-
-
0038177199
-
"Diaryl pyrazoles as inhibitors of COX-2"
-
M.R. Cuberes-Altisent, J.M. Berrocal-Romero, M.M. Contijoch-Llobet and J. Frigola-Constansa: "Diaryl pyrazoles as inhibitors of COX-2", Chem. Abstr., Vol. 132, (2000), 12302g.
-
(2000)
Chem. Abstr.
, vol.132
-
-
Cuberes-Altisent, M.R.1
Berrocal-Romero, J.M.2
Contijoch-Llobet, M.M.3
Frigola-Constansa, J.4
-
114
-
-
33644615593
-
"Preparation of heterocyclyl sulfonylbenzene compounds as anti-inflammatory/analgesic agents"
-
K. Ando, T. Kato, A. Kawai and T. Nonomura: "Preparation of heterocyclyl sulfonylbenzene compounds as anti-inflammatory/analgesic agents", Chem. Abstr., Vol. 132, (2000), 35714g.
-
(2000)
Chem. Abstr.
, vol.132
-
-
Ando, K.1
Kato, T.2
Kawai, A.3
Nonomura, T.4
-
115
-
-
33644617971
-
"Synthesis and use of heteroaryl phenyl pyrazoles as anti-inflammatory/analgesic agents"
-
K. Ando, K. Kawamura, T. Kato, M.L. Minich, K.M. Lundy, H. Cheng, J. Li, B.S. Bronk, S.M. Sakya: "Synthesis and use of heteroaryl phenyl pyrazoles as anti-inflammatory/analgesic agents", Chem. Abstr., Vol. 135, (2001), 19659z.
-
(2001)
Chem. Abstr.
, vol.135
-
-
Ando, K.1
Kawamura, K.2
Kato, T.3
Minich, M.L.4
Lundy, K.M.5
Cheng, H.6
Li, J.7
Bronk, B.S.8
Sakya, S.M.9
-
116
-
-
4143076782
-
"Preparation of sulfamoyal hetero aryl pyrazole compound as anti-inflammatory and analgesic agents"
-
K. Ando and K. Kawamura: "Preparation of sulfamoyal hetero aryl pyrazole compound as anti-inflammatory and analgesic agents", Chem. Abstr., Vol. 135, (2001), 33472q.
-
(2001)
Chem. Abstr.
, vol.135
-
-
Ando, K.1
Kawamura, K.2
-
117
-
-
0035695436
-
"Antiinflammatory activity of a novel selective cyclooxygenase-2 inhibitor, FR 140423 on type II collagen-induced arthritis in Lewi's rats"
-
T. Ochi and T. Goto: "Antiinflammatory activity of a novel selective cyclooxygenase-2 inhibitor, FR 140423 on type II collagen-induced arthritis in Lewi's rats", Prostaglandins and other Lipid Mediators, Vol. 66, (2001), pp. 317-327.
-
(2001)
Prostaglandins and Other Lipid Mediators
, vol.66
, pp. 317-327
-
-
Ochi, T.1
Goto, T.2
-
118
-
-
33644610862
-
"Preparation of substituted pyrimidines as selective cyclooxygenase-2 inhibitors"
-
M.C. Carter, A. Naylor, M. Pass, J.J. Payne and N.A. Pegg: "Preparation of substituted pyrimidines as selective cyclooxygenase-2 inhibitors", Chem. Abstr., Vol. 136, (2002), 216760x.
-
(2002)
Chem. Abstr.
, vol.136
-
-
Carter, M.C.1
Naylor, A.2
Pass, M.3
Payne, J.J.4
Pegg, N.A.5
-
119
-
-
33644616512
-
"Preparation of 3-aryl pyridines as cyclooxygenase inhibitors"
-
J. Ishida, H. Yamamoto, N. Konishi, M. Morita, K. Nakamura, S. Miyata, T. Ochi, Y. Morita, E. Yoshimi and K. Kuroda: "Preparation of 3-aryl pyridines as cyclooxygenase inhibitors", Chem. Abstr., Vol. 137, (2002), 109211b.
-
(2002)
Chem. Abstr.
, vol.137
-
-
Ishida, J.1
Yamamoto, H.2
Konishi, N.3
Morita, M.4
Nakamura, K.5
Miyata, S.6
Ochi, T.7
Morita, Y.8
Yoshimi, E.9
Kuroda, K.10
-
120
-
-
33644614791
-
"Preparation of 2,3-diarylpyridines as selective cyclooxygenase-2-inhibitors"
-
R.M. Weier, L.F. Lee, R.A. Partis and F.J. Koszyk: "Preparation of 2,3-diarylpyridines as selective cyclooxygenase-2-inhibitors", Chem. Abstr., Vol. 131, (1999), 73565w.
-
(1999)
Chem. Abstr.
, vol.131
-
-
Weier, R.M.1
Lee, L.F.2
Partis, R.A.3
Koszyk, F.J.4
-
121
-
-
0008092732
-
"Preparation of substituted pyridines as as cyclooxygenase inhibitors"
-
D. Dube, R. Fortin, R. Friesen, Z. Wang and J.X. Gauthier: "Preparation of substituted pyridines as as cyclooxygenase inhibitors", Chem. Abstr., Vol. 128, (1998), 140614q.
-
(1998)
Chem. Abstr.
, vol.128
-
-
Dube, D.1
Fortin, R.2
Friesen, R.3
Wang, Z.4
Gauthier, J.X.5
-
122
-
-
0008149569
-
"Prepartion of pyridinyl -2- cyclopenten-1-ones as selective cyclooxygenase-2 inhibitors"
-
C. Black, G. Hughes and Z. Wang: "Prepartion of pyridinyl -2- cyclopenten-1-ones as selective cyclooxygenase-2 inhibitors", Chem. Abstr., Vol. 128, (1998), 13207j.
-
(1998)
Chem. Abstr.
, vol.128
-
-
Black, C.1
Hughes, G.2
Wang, Z.3
-
123
-
-
33644633308
-
"Preparation of benzofuran-2-carbonitriles and benzothiophene-2-carbonitriles as anti-inflammatory agents"
-
K.L. McLaren, D.B. Smith and J.L. Tracy: "Preparation of benzofuran-2-carbonitriles and benzothiophene-2-carbonitriles as anti-inflammatory agents", Chem. Abstr., Vol. 137, (2002), 20293y.
-
(2002)
Chem. Abstr.
, vol.137
-
-
McLaren, K.L.1
Smith, D.B.2
Tracy, J.L.3
-
124
-
-
33644626214
-
"Anti-inflammatory evaluation and synthesis of benzothiazine derivatives as cycloxygenase-2-inhibitor"
-
H.S. Shin, M.S. Park and S.K. Kwon: "Anti-inflammatory evaluation and synthesis of benzothiazine derivatives as cycloxygenase-2-inhibitor", Yakhak Hoechi, Vol. 44, (2000), pp. 272-278.
-
(2000)
Yakhak Hoechi
, vol.44
, pp. 272-278
-
-
Shin, H.S.1
Park, M.S.2
Kwon, S.K.3
-
125
-
-
33644624896
-
"Preparation of pyrazolo [1,5-b] pyridazines as selective inhibitors of COX-2"
-
G.J. Dear and K. Gohil: "Preparation of pyrazolo [1,5-b] pyridazines as selective inhibitors of COX-2", Chem. Abstr., Vol. 136, (2002), 340687t.
-
(2002)
Chem. Abstr.
, vol.136
-
-
Dear, G.J.1
Gohil, K.2
-
126
-
-
33644625286
-
"Preparation of pyrazolopyridines as selective inhibitors of COX-2 inhibitors"
-
I.B. Campbell and A. Naylor: "Preparation of pyrazolopyridines as selective inhibitors of COX-2 inhibitors", Chem. Abstr., Vol. 132, (2000), 321858a.
-
(2000)
Chem. Abstr.
, vol.132
-
-
Campbell, I.B.1
Naylor, A.2
-
127
-
-
0008143428
-
"Preparation of cyclo oxygenase- 2 -inhibiting- 2, 3- diphenylimidazo [1,2-a] pyridine anti inflammatories"
-
P.J. Beswick, I.B. Campbell and A. Naylor: "Preparation of cyclo oxygenase- 2 -inhibiting- 2, 3- diphenylimidazo [1,2-a] pyridine anti inflammatories", Chem. Abstr., Vol. 126, (1997), 8117j.
-
(1997)
Chem. Abstr.
, vol.126
-
-
Beswick, P.J.1
Campbell, I.B.2
Naylor, A.3
-
128
-
-
46649109795
-
"Preparation of benzopyran carboxylates and quinoline carboxylates as selective cyclooxygenase-2-inhibitors"
-
J. S. Carter, M.G. Obukowicz, B. Devadas, J.J. Talley, D.L. Brown, M.J. Graneto, S.R. Bertenshaw, D.J.Jr. Rogier, S.R. Nagarajan, C.E. Hanan, S.J. Hartmann, C.L. Ludwig, S. Metz and D.E. Korte: "Preparation of benzopyran carboxylates and quinoline carboxylates as selective cyclooxygenase-2-inhibitors", Chem. Abstr., Vol. 133, (2000), 43440a.
-
(2000)
Chem. Abstr.
, vol.133
-
-
Carter, J.S.1
Obukowicz, M.G.2
Devadas, B.3
Talley, J.J.4
Brown, D.L.5
Graneto, M.J.6
Bertenshaw, S.R.7
Rogier Jr., D.J.8
Nagarajan, S.R.9
Hanan, C.E.10
Hartmann, S.J.11
Ludwig, C.L.12
Metz, S.13
Korte, D.E.14
-
129
-
-
0033393733
-
"Selective anti-inflammatory inhibitors of 2-cyclo-oxygenase"
-
M.N. Riera: "Selective anti-inflammatory inhibitors of 2-cyclo-oxygenase", Cienc, Tecnol. Pharm., Vol. 9, (1999), pp. 157-164.
-
(1999)
Cienc, Tecnol. Pharm.
, vol.9
, pp. 157-164
-
-
Riera, M.N.1
-
130
-
-
0034823297
-
"Tolerability to new COX-2 inhibitors in NSAIDs-sensitive patients with cutaneous reactions"
-
M.S. Borges, H.A. Capriles, F.F. Caballero and C.R. Perez: "Tolerability to new COX-2 inhibitors in NSAIDs-sensitive patients with cutaneous reactions", Annals of Allergy, Asthma & Immunology, Vol. 87, (2001), pp. 201-204.
-
(2001)
Annals of Allergy, Asthma & Immunology
, vol.87
, pp. 201-204
-
-
Borges, M.S.1
Capriles, H.A.2
Caballero, F.F.3
Perez, C.R.4
-
131
-
-
0034754976
-
"In vitro effects of cyclo oxygenase inhibitors in whole blood of horses, dogs and cats"
-
C. Brideau, S.C. Van and C.C. Chan: "In vitro effects of cyclo oxygenase inhibitors in whole blood of horses, dogs and cats", American Journal of Veterinary Research, Vol. 62, (2001), pp. 1755-1760.
-
(2001)
American Journal of Veterinary Research
, vol.62
, pp. 1755-1760
-
-
Brideau, C.1
Van, S.C.2
Chan, C.C.3
-
132
-
-
0036123619
-
"Safety of selective cyclooxygenase-2-inhibitors in inflammatory bowel disease"
-
U. Mahadevan, E.V.Jr. Loftus, W.J. Tremaine and W.J. Sandborn: "Safety of selective cyclooxygenase-2-inhibitors in inflammatory bowel disease", American Journal of Gasteroenterology, Vol. 97, (2002), pp. 910-917.
-
(2002)
American Journal of Gasteroenterology
, vol.97
, pp. 910-917
-
-
Mahadevan, U.1
Loftus Jr., E.V.2
Tremaine, W.J.3
Sandborn, W.J.4
-
133
-
-
0034816925
-
"Cyclooxygenase- independent actions of cyclooxygenase inhibitors"
-
I. Tegeder, J. Pfeilschirer and G. Geisslinger: "Cyclooxygenase- independent actions of cyclooxygenase inhibitors", FASEB Journal, Vol. 15, (2001), pp. 2057-2072.
-
(2001)
FASEB Journal
, vol.15
, pp. 2057-2072
-
-
Tegeder, I.1
Pfeilschirer, J.2
Geisslinger, G.3
-
134
-
-
0035167665
-
"Effect of nonsteroidal anti-inflammatory drugs on lipoxygenase and cyclooxygenase activities on human colon segments from patients with neoplasia"
-
G. Di Girolamo, A. Franchi, A.R. De Las Santos, M.L. Marti, M. Farina, D.G. Fernandez and A. Mortha: "Effect of nonsteroidal anti-inflammatory drugs on lipoxygenase and cyclooxygenase activities on human colon segments from patients with neoplasia", Medicina (Buenas Aries, Argentina), Vol. 61(5/1), (2001), pp. 566-572.
-
(2001)
Medicina (Buenas Aries, Argentina)
, vol.61
, Issue.5-11
, pp. 566-572
-
-
Di Girolamo, G.1
Franchi, A.2
De Las Santos, A.R.3
Marti, M.L.4
Farina, M.5
Fernandez, D.G.6
Mortha, A.7
-
135
-
-
33644636045
-
2production in human mesangial cells"
-
2production in human mesangial cells", Mianyixue Zazhi, Vol. 17, (2001), pp. 421-424.
-
(2001)
Mianyixue Zazhi
, vol.17
, pp. 421-424
-
-
Wu, Y.1
Chen, R.2
Chen, J.3
Zhang, A.4
Pan, X.5
-
136
-
-
30744478101
-
"Preparaion of 1,2-substituted benzimidazole derivatives as antiallergic agents"
-
T. Sato, T. Taguchi, H. Nakano, T. Inoue and N. Kawasaki: "Preparaion of 1,2-substituted benzimidazole derivatives as antiallergic agents", Chem. Abstr., Vol. 133, (2000), 238002s.
-
(2000)
Chem. Abstr.
, vol.133
-
-
Sato, T.1
Taguchi, T.2
Nakano, H.3
Inoue, T.4
Kawasaki, N.5
-
137
-
-
4243324517
-
"Preparation of pyrimidinecarboxamides and Pyrazine carboxamides for treating inflammatory conditions"
-
M.J. Suto, M.E. Goldman, L.M. Gayo, L.J. Ransome-Fong, M.S.S. Palanki and R.W. Sullivan: "Preparation of pyrimidinecarboxamides and Pyrazine carboxamides for treating inflammatory conditions", Chem. Abstr., Vol. 126, (1997), 264109g.
-
(1997)
Chem. Abstr.
, vol.126
-
-
Suto, M.J.1
Goldman, M.E.2
Gayo, L.M.3
Ransome-Fong, L.J.4
Palanki, M.S.S.5
Sullivan, R.W.6
-
138
-
-
33644618422
-
"Preparation of imidazopyridine derivatives as inflammation inhibitors"
-
S. Yasufuka and A. Motonaga: "Preparation of imidazopyridine derivatives as inflammation inhibitors", Chem. Abstr., Vol. 120, (1994), 164170c.
-
(1994)
Chem. Abstr.
, vol.120
-
-
Yasufuka, S.1
Motonaga, A.2
-
139
-
-
33644622313
-
"Preparation of N-pyridylmethoxybenzyl)-N-hydroxy ureas as lipoxygenase inhibitors and thromboxane synthetase inhibitors"
-
T. Komatsu, Y. Kawaharra, T. Fuji, M. Takano and N. Hara: "Preparation of N-pyridylmethoxybenzyl)-N-hydroxy ureas as lipoxygenase inhibitors and thromboxane synthetase inhibitors", Chem. Abstr., Vol. 125, (1996), 247620d.
-
(1996)
Chem. Abstr.
, vol.125
-
-
Komatsu, T.1
Kawaharra, Y.2
Fuji, T.3
Takano, M.4
Hara, N.5
-
141
-
-
0346790176
-
"Preparation of novel thiazolopyrimidines as modulators of chemokine receptor activity"
-
R. Austin, A. Baxter, R. Bonnett, F. Hunt, F. Kinchin and P. Willis: "Preparation of novel thiazolopyrimidines as modulators of chemokine receptor activity", Chem. Abstr., Vol. 132, (2000), 166252c.
-
(2000)
Chem. Abstr.
, vol.132
-
-
Austin, R.1
Baxter, A.2
Bonnett, R.3
Hunt, F.4
Kinchin, F.5
Willis, P.6
-
142
-
-
33644626647
-
"Preparation of 1,2,3,4-tetrahydro acridines and analogs as inhibitors of interleukin I"
-
J.S. Skotnicki and S.C. Gilman : "Preparation of 1,2,3,4-tetrahydro acridines and analogs as inhibitors of interleukin I", Chem. Abstr., Vol. 112, (1990), 118672e.
-
(1990)
Chem. Abstr.
, vol.112
-
-
Skotnicki, J.S.1
Gilman, S.C.2
-
143
-
-
0142162685
-
"Preparation of 2-substituted imidazoles useful in the treatment of inflammatory diseases"
-
M. Wachter and S.A. Beers: "Preparation of 2-substituted imidazoles useful in the treatment of inflammatory diseases", Chem. Abstr., Vol. 130, (1999), 139340g.
-
(1999)
Chem. Abstr.
, vol.130
-
-
Wachter, M.1
Beers, S.A.2
-
144
-
-
33644623257
-
"Preparation of substituted imidazoles useful in the treatment of inflammatory diseases"
-
S.A. Beers, E. Malloy, M.P. Wachter and W. Wu: "Preparation of substituted imidazoles useful in the treatment of inflammatory diseases", Chem. Abstr., Vol. 129, (1998), 330728y.
-
(1998)
Chem. Abstr.
, vol.129
-
-
Beers, S.A.1
Malloy, E.2
Wachter, M.P.3
Wu, W.4
-
145
-
-
0034685192
-
"COX-1, COX-2 and COX-3 and the future treatment of Chronic inflammatory disease"
-
D.A. Willoghby, A.R. Moore, N. Colville and R. Paul: "COX-1, COX-2 and COX-3 and the future treatment of Chronic inflammatory disease", Lancet, Vol. 355(9204), (2000), pp. 646-648.
-
(2000)
Lancet
, vol.355
, Issue.9204
, pp. 646-648
-
-
Willoghby, D.A.1
Moore, A.R.2
Colville, N.3
Paul, R.4
|