Solid-phase synthesis and inhibitory effects of some pyrido[1,2-c]pyrimidine derivatives on leukocyte functions and experimental inflammation

Journal of Medicinal Chemistry

Volumn 44, Issue 6, 2001, Pages 1011-1014

  Molina, P ^a   Aller, E ^a   Lorenzo, A ^a   Lopez Cremades P ^a   Rioja, I ^b   Ubeda, A ^b   Terencio, Ma C ^b   Alcaraz, Ma J ^b  

^a UNIVERSITY OF MURCIA   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; LIPOPOLYSACCHARIDE; PHORBOL 13 ACETATE 12 MYRISTATE; PROSTAGLANDIN E2; PYRIDO[1,2 C]PYRIMIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHEMOLUMINESCENCE; DRUG SYNTHESIS; ENZYME ACTIVITY; INFLAMMATION; LEUKOCYTE FUNCTION; MACROPHAGE; METABOLIC INHIBITION; MOUSE; NONHUMAN;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELLS, CULTURED; CHEMILUMINESCENT MEASUREMENTS; CYCLOOXYGENASE 2; DINOPROSTONE; EDEMA; FREE RADICAL SCAVENGERS; HUMANS; ISOENZYMES; LIPOPOLYSACCHARIDES; MACROPHAGES; MEMBRANE PROTEINS; MICE; NEUTROPHIL ACTIVATION; NEUTROPHILS; PANCREATIC ELASTASE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; TETRADECANOYLPHORBOL ACETATE;

EID: 0035866588     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm000997g     Document Type: Article

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