Mouse models of senile osteoporosis

Molecular Aspects of Medicine

Volumn 26, Issue 3, 2005, Pages 221-231

  Watanabe, Ken ^a   Hishiya, Akinori ^a  

^a National Center for Geriatrics and Gerontology   (Japan)

Author keywords

Osteoblast; Premature aging; Senile osteoporosis; Stem cell

Indexed keywords

DNA;

AGING; DNA REPAIR; DNA REPLICATION; NONHUMAN; PATHOGENESIS; PHENOTYPE; REVIEW; SENILE OSTEOPOROSIS; STEM CELL; TELOMERE;

RODENTIA;

EID: 16244377495     PISSN: 00982997     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mam.2005.01.006     Document Type: Review

References (57)

1. C. Barlow, S. Hirotsune, R. Paylor, M. Liyanage, M. Eckhaus, F. Collins, Y. Shiloh, J.N. Crawley, T. Ried, D. Tagle, and A. Wynshaw-Boris Atm-deficient mice: a paradigm of ataxia telangiectasia Cell 86 1996 159 171
2. R.J. Bergman, D. Gazit, A.J. Kahn, H. Gruber, S. McDougall, and T.J. Hahn Age-related changes in osteogenic stem cells in mice J. Bone Miner. Res. 11 1996 568 577
3. D.D. Bikle, T. Sakata, C. Leary, H. Elalieh, D. Ginzinger, C.J. Rosen, W. Beamer, S. Majumdar, and B.P. Halloran Insulin-like growth factor I is required for the anabolic actions of parathyroid hormone on mouse bone J. Bone Miner. Res. 17 2002 1570 1578
4. J.P. Bilezikian, L.G. Raisz, and G.A. Rodan Principles of bone biology 2002 Academic Press San Diego, CA
5. M. Bonyadi, S.D. Waldman, D. Liu, J.E. Aubin, M.D. Grynpas, and W.L. Stanford Mesenchymal progenitor self-renewal deficiency leads to age-dependent osteoporosis in Sca-1/Ly-6A null mice Proc. Natl. Acad. Sci. USA 100 2003 5840 5845
6. J. Cao, L. Venton, T. Sakata, and B.P. Halloran Expression of RANKL and OPG correlates with age-related bone loss in male C57BL/6 mice J. Bone Miner. Res. 18 2003 270 277
7. S. Chang, A.S. Multani, N.G. Cabrera, M.L. Naylor, P. Laud, D. Lombard, S. Pathak, L. Guarente, and R.A. DePinho Essential role of limiting telomeres in the pathogenesis of Werner syndrome Nat. Genet. 36 2004 877 882
8. R.A. Davey, H.E. MacLean, J.F. McManus, D.M. Findlay, and J.D. Zajac Genetically modified animal models as tools for studying bone and mineral metabolism J. Bone Miner. Res. 19 2004 882 892
9. A. De Sandre-Giovannoli, R. Bernard, P. Cau, C. Navarro, J. Amiel, I. Boccaccio, S. Lyonnet, C.L. Stewart, A. Munnich, M. Le Merrer, and N. Levy Lamin A truncation in Hutchinson-Gilford progeria Science 300 2003 2055
10. X. Du, J. Shen, N. Kugan, E.E. Furth, D.B. Lombard, C. Cheung, S. Pak, G. Luo, R.J. Pignolo, R.A. DePinho, L. Guarente, and F.B. Johnson Telomere shortening exposes functions for the mouse werner and bloom syndrome genes Mol. Cell Biol. 24 2004 8437 8446
11. A. Elson, Y. Wang, C.J. Daugherty, C.C. Morton, F. Zhou, J. Campos-Torres, and P. Leder Pleiotropic defects in ataxia-telangiectasia protein-deficient mice Proc. Natl. Acad. Sci. USA 93 1996 13084 13089
12. M. Eriksson, W.T. Brown, L.B. Gordon, M.W. Glynn, J. Singer, L. Scott, M.R. Erdos, C.M. Robbins, T.Y. Moses, P. Berglund, A. Dutra, E. Pak, S. Durkin, A.B. Csoka, M. Boehnke, T.W. Glover, and F.S. Collins Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome Nature 423 2003 293 298
13. V.L. Ferguson, R.A. Ayers, T.A. Bateman, and S.J. Simske Bone development and age-related bone loss in male C57BL/6J mice Bone 33 2003 387 398
14. K. Flurkey, J. Papaconstantinou, R.A. Miller, and D.E. Harrison Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production Proc. Natl. Acad. Sci. USA 98 2001 6736 6741
15. P. Ghia, F. Melchers, and A.G. Rolink Age-dependent changes in B lymphocyte development in man and mouse Exp. Gerontol. 35 2000 159 165
16. O. Hantschel, and G. Superti-Furga Regulation of the c-Abl and Bcr-Abl tyrosine kinases Nat. Rev. Mol. Cell Biol. 5 2004 33 44
17. L. Hartwell Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells Cell 71 1992 543 546
18. P. Hasty, J. Campisi, J. Hoeijmakers, H. van Steeg, and J. Vijg Aging and genome maintenance: lessons from the mouse? Science 299 2003 1355 1359
19. P. Hasty, and J. Vijg Accelerating aging by mouse reverse genetics: a rational approach to understanding longevity Aging Cell 3 2004 55 65
20. A. Hishiya, and K. Watanabe Progeroid syndrome as a model for impaired bone formation in senile osteoporosis J. Bone Miner. Metab. 22 2004 399 403
21. M. Holzenberger, J. Dupont, B. Ducos, P. Leneuve, A. Geloen, P.C. Even, P. Cervera, and Y. Le Bouc IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice Nature 421 2003 182 187
22. C.Y. Ito, C.Y. Li, A. Bernstein, J.E. Dick, and W.L. Stanford Hematopoietic stem cell and progenitor defects in Sca-1/Ly-6A-null mice Blood 101 2003 517 523
23. R.L. Jilka, R.S. Weinstein, K. Takahashi, A.M. Parfitt, and S.C. Manolagas Linkage of decreased bone mass with impaired osteoblastogenesis in a murine model of accelerated senescence J. Clin. Invest. 97 1996 1732 1740
24. O. Kajkenova, B. Lecka-Czernik, I. Gubrij, S.P. Hauser, K. Takahashi, A.M. Parfitt, R.L. Jilka, S.C. Manolagas, and D.A. Lipschitz Increased adipogenesis and myelopoiesis in the bone marrow of SAMP6, a murine model of defective osteoblastogenesis and low turnover osteopenia J. Bone Miner. Res. 12 1997 1772 1779
25. H. Kawaguchi, N. Manabe, C. Miyaura, H. Chikuda, K. Nakamura, and M. Kuro-o Independent impairment of osteoblast and osteoclast differentiation in Klotho mouse exhibiting low-turnover osteopenia J. Clin. Invest. 104 1999 229 237
26. S. Kharbanda, Z.M. Yuan, R. Weichselbaum, and D. Kufe Functional role for the c-Abl protein tyrosine kinase in the cellular response to genotoxic stress Biochim. Biophys. Acta 1333 1997 O1 O7
27. D. Kipling, T. Davis, E.L. Ostler, and R.G. Faragher What can progeroid syndromes tell us about human aging? Science 305 2004 1426 1431
28. M. Kuro-o Disease model: human aging Trends Mol. Med. 7 2001 179 181
29. M. Kuro-o, Y. Matsumura, H. Aizawa, H. Kawaguchi, T. Suga, T. Utsugi, Y. Ohyama, M. Kurabayashi, T. Kaname, E. Kume, H. Iwasaki, A. Iida, T. Shiraki-Iida, S. Nishikawa, R. Nagai, and Y.I. Nabeshima Mutation of the mouse Klotho gene leads to a syndrome resembling ageing Nature 390 1997 45 51
30. M.F. Lavin, and Y. Shiloh The genetic defect in ataxia-telangiectasia Annu. Rev. Immunol. 15 1997 177 202
31. J. LeMaoult, J.S. Manavalan, R. Dyall, P. Szabo, J. Nikolic-Zugic, and M.E. Weksler Cellular basis of B cell clonal populations in old mice J. Immunol. 162 1999 6384 6391
32. B. Li, S. Boast, K. de los Santos, I. Schieren, M. Quiroz, S.L. Teitelbaum, M.M. Tondravi, and S.P. Goff Mice deficient in Abl are osteoporotic and have defects in osteoblast maturation Nat. Genet. 24 2000 304 308
33. B. Li, X. Wang, N. Rasheed, Y. Hu, S. Boast, T. Ishii, K. Nakayama, K.I. Nakayama, and S.P. Goff Distinct roles of c-Abl and Atm in oxidative stress response are mediated by protein kinase C delta Genes Dev. 18 2004 1824 1837
34. D.B. Lombard, C. Beard, B. Johnson, R.A. Marciniak, J. Dausman, R. Bronson, J.E. Buhlmann, R. Lipman, R. Curry, A. Sharpe, R. Jaenisch, and L. Guarente Mutations in the WRN gene in mice accelerate mortality in a p53-null background Mol. Cell Biol. 20 2000 3286 3291
35. B. Maier, W. Gluba, B. Bernier, T. Turner, K. Mohammad, T. Guise, A. Sutherland, M. Thorner, and H. Scrable Modulation of mammalian life span by the short isoform of p53 Genes Dev. 18 2004 306 319
36. M. Matsushita, T. Tsuboyama, R. Kasai, H. Okumura, T. Yamamuro, K. Higuchi, A. Kohno, T. Yonezu, and A. Utani Age-related changes in bone mass in the senescence-accelerated mouse (SAM). SAM-R/3 and SAM-P/6 as new murine models for senile osteoporosis Am. J. Pathol. 125 1986 276 283
37. E. Migliaccio, M. Giorgio, S. Mele, G. Pelicci, P. Reboldi, P.P. Pandolfi, L. Lanfrancone, and P.G. Pelicci The p66shc adaptor protein controls oxidative stress response and life span in mammals Nature 402 1999 309 313
38. S.J. Morrison, A.M. Wandycz, K. Akashi, A. Globerson, and I.L. Weissman The aging of hematopoietic stem cells Nat. Med. 2 1996 1011 1016
39. J. Moskovitz, S. Bar-Noy, W.M. Williams, J. Requena, B.S. Berlett, and E.R. Stadtman Methionine sulfoxide reductase (MsrA) is a regulator of antioxidant defense and lifespan in mammals Proc. Natl. Acad. Sci. USA 98 2001 12920 12925
40. L.C. Mounkes, S. Kozlov, L. Hernandez, T. Sullivan, and C.L. Stewart A progeroid syndrome in mice is caused by defects in A-type lamins Nature 423 2003 298 301
41. T. Nagai, K. Yamada, H.C. Kim, Y.S. Kim, Y. Noda, A. Imura, Y. Nabeshima, and T. Nabeshima Cognition impairment in the genetic model of aging Klotho gene mutant mice: a role of oxidative stress Faseb. J. 17 2003 50 52
42. C.A. Neumann, D.S. Krause, C.V. Carman, S. Das, D.P. Dubey, J.L. Abraham, R.T. Bronson, Y. Fujiwara, S.H. Orkin, and R.A. Van Etten Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression Nature 424 2003 561 565
43. P. Nurse Checkpoint pathways come of age Cell 91 1997 865 867
44. S.L. Perkins, R. Gibbons, S. Kling, and A.J. Kahn Age-related bone loss in mice is associated with an increased osteoclast progenitor pool Bone 15 1994 65 72
45. G. Rotman, and Y. Shiloh ATM: from gene to function Hum. Mol. Genet. 7 1998 1555 1563
46. M.J. Silva, M.D. Brodt, and S.L. Ettner Long bones from the senescence accelerated mouse SAMP6 have increased size but reduced whole-bone strength and resistance to fracture J. Bone Miner. Res. 17 2002 1597 1603
47. W.L. Stanford, S. Haque, R. Alexander, X. Liu, A.M. Latour, H.R. Snodgrass, B.H. Koller, and P.M. Flood Altered proliferative response by T lymphocytes of Ly-6A (Sca-1) null mice J. Exp. Med. 186 1997 705 717
48. L.Q. Sun, D.W. Lee, Q. Zhang, W. Xiao, E.H. Raabe, A. Meeker, D. Miao, D.L. Huso, and R.J. Arceci Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG Genes Dev. 18 2004 1035 1046
49. T. Takeda, T. Matsushita, M. Kurozumi, K. Takemura, K. Higuchi, and M. Hosokawa Pathobiology of the senescence-accelerated mouse (SAM) Exp. Gerontol. 32 1997 117 127
50. A. Trifunovic, A. Wredenberg, M. Falkenberg, J.N. Spelbrink, A.T. Rovio, C.E. Bruder, Y.M. Bohlooly, S. Gidlof, A. Oldfors, R. Wibom, J. Tornell, H.T. Jacobs, and N.G. Larsson Premature ageing in mice expressing defective mitochondrial DNA polymerase Nature 429 2004 417 423
51. S.D. Tyner, S. Venkatachalam, J. Choi, S. Jones, N. Ghebranious, H. Igelmann, X. Lu, G. Soron, B. Cooper, C. Brayton, S. Hee Park, T. Thompson, G. Karsenty, A. Bradley, and L.A. Donehower p53 mutant mice that display early ageing-associated phenotypes Nature 415 2002 45 53
52. H. Vogel, D.S. Lim, G. Karsenty, M. Finegold, and P. Hasty Deletion of Ku86 causes early onset of senescence in mice Proc. Natl. Acad. Sci. USA 96 1999 10770 10775
53. H.R. Warner, and F. Sierra Models of accelerated ageing can be informative about the molecular mechanisms of ageing and/or age-related pathology Mech. Ageing Dev. 124 2003 581 587
54. Y. Xu, T. Ashley, E.E. Brainerd, R.T. Bronson, M.S. Meyn, and D. Baltimore Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, thymic lymphoma Genes Dev. 10 1996 2411 2422
55. E.T. Yeh, H. Reiser, B. Benacerraf, and K.L. Rock The expression, function, ontogeny of a novel T cell-activating protein, TAP, in the thymus J. Immunol. 137 1986 1232 1238
56. C.E. Yu, J. Oshima, Y.H. Fu, E.M. Wijsman, F. Hisama, R. Alisch, S. Matthews, J. Nakura, T. Miki, S. Ouais, G.M. Martin, J. Mulligan, and G.D. Schellenberg Positional cloning of the Werner's syndrome gene Science 272 1996 258 262
57. M. Zhang, S. Xuan, M.L. Bouxsein, D. von Stechow, N. Akeno, M.C. Faugere, H. Malluche, G. Zhao, C.J. Rosen, A. Efstratiadis, and T.L. Clemens Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization J. Biol. Chem. 277 2002 44005 44012