Cytoskeletal disruption is the key factor that triggers apoptosis in okadaic acid-treated neuroblastoma cells

Archives of Toxicology

Volumn 78, Issue 2, 2004, Pages 74-85

  Cabado, A G ^a   Leira, F ^a   Vieytes, M R ^b   Vieites, J M ^a   Botana, L M ^b  

^a UNIVERSITY OF VIGO   (Spain)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Apoptosis; Cytoskeleton; Mitochondria; Neuroblastoma cells; Okadaic acid

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; ACETYLASPARTYLGLUTAMYLVALYLASPARTIC ACID ALDEHYDE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 3 INHIBITOR; CHELERYTHRINE; CYTOCHROME C; DNA FRAGMENT; F ACTIN; FORSKOLIN; GENISTEIN; HERBIMYCIN A; KT 5720; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; OKADAIC ACID; PROTEIN BAX; PROTEIN BCL 2; ROTTLERIN; UNCLASSIFIED DRUG; WORTMANNIN;

APOPTOSIS; ARTICLE; CYTOSKELETON; DRUG EFFECT; ENZYME ACTIVATION; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NEUROBLASTOMA CELL; PRIORITY JOURNAL;

ACTINS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASES; CELL LINE, TUMOR; CYTOCHROMES C; CYTOSKELETON; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; ENZYME INHIBITORS; HUMANS; MEMBRANE POTENTIALS; MITOCHONDRIA; NEUROBLASTOMA; OKADAIC ACID; PHARMACEUTICAL PREPARATIONS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 1542283580     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-003-0505-4     Document Type: Article

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