Alterations in focal adhesion and cytoskeletal proteins during apoptosis

Anticancer Research

Volumn 18, Issue 1 A, 1998, Pages 301-307

  Marushige, Yasuko ^a   Marushige, Keiji ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Apoptosis; Calyculin A; Ceramide; Cytoskeletal proteins; Focal adhesion proteins; Orthovanadate; Trigeminal neurinoma cells

Indexed keywords

ACTIN; BETA TUBULIN; CALYCULIN A; CELL ADHESION MOLECULE; CERAMIDE; CYTOSKELETON PROTEIN; FOCAL ADHESION KINASE; ORTHOVANADIC ACID; PAXILLIN; PHOSPHOTYROSINE; VIMENTIN; VINCULIN;

ADHERENT CELL; ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL SHAPE; CONTROLLED STUDY; IMMUNOBLOTTING; METAPHASE; MOLECULAR WEIGHT; NEURINOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RAT;

ANIMALS; APOPTOSIS; CELL ADHESION; CELL ADHESION MOLECULES; CERAMIDES; CYTOSKELETAL PROTEINS; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; NEURILEMMOMA; PAXILLIN; PHOSPHOPROTEINS; PHOSPHOTYROSINE; PROTEIN-TYROSINE KINASES; RATS; TRIGEMINAL NERVE; TUMOR CELLS, CULTURED; VINCULIN;

EID: 0031923446     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Meredith JE Jr, Fazeli B and Schwanz MA: The extracellular matrix as a survival factor. Mol Biol Cell 4: 953-961, 1993.
2. Frisch SM and Francis H: Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol 124: 619-626, 1994.
3. Jockusch BM, Bubeck P, Giehl K, Kroemker M, Moschner J, Rothkegel M, Rüdiger M, Schlüter K, Stanke G and Winkler J: The molecular architecture of focal adhesions. Annu Rev Cell Dev Biol 11: 379-416, 1995.
4. Burridge K and Chrzanowska-Wodnicka M: Focal adhesions, contractility, and signaling. Annu Rev Cell Dev Biol 12: 463-518, 1996.
5. Eriksson JE, Brautigan DL, Vallee R, Olmsted J, Fujiki H and Goldman RD: Cytoskeletal integrity in interphase cells requires protein phosphatase activity. Proc Natl Acad Sci USA 89: 11093-11097, 1992.
6. FAK accompanies cell adhesion to extracellular matrix: A role in cytoskeletal assembly. J Cell Biol 119: 893-903, 1992.
7. Hanks SK, Calalb MB, Harper MC and Patel SK: Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin. Proc Natl Acad Sci USA 89: 8487-8491. 1992.
8. FAK tyrosine phosphorylation and focal adhesion assembly: Studies with phosphoryrosine phosphatase inhibitors. Exp Cell Res 221: 141-152, 1995.
9. FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk. Mol Cell Biol 15: 2635-2645, 1995.
10. Schlaepfer DD, Hanks SK, Hunter T and van der Geer P: Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 372: 786-791, 1994.
11. Marushige K and Marushige Y: Modulation of cell rounding and apoptosis in trigeminal neurinoma cells by protein phosphatase inhibitors. Anticancer Res 18: 295-300, 1998.
12. Nickel BE, Roth SY, Cook RG, Allis CD and Davie J: Changes in the histone H2A variant H2A.Z and polyubiquitinated histone species in developing trout testis. Biochemistry 26: 4417-4421, 1987.
13. Turner CE, Glenney JR Jr and Burridge K: Paxillin: A new vinculinbinding protein present in focal adhesions. J Cell Biol 111: 1059-1068, 1990.
14. BCR/ABL. J Biol Chem 270: 5039-5047, 1995.
15. Zachary I, Sinnett-Smith J, Turner CE and Rozengurt E: Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation of the focal adhesion-associated protein paxillin in Swiss 3T3 cells. J Biol Chem 268: 22060-22065, 1993.
16. 1-induced apoptosis. Anticancer Res 15: 267-272, 1995.
17. Maher PA: Activation of phosphotyrosine phosphatase by reduction of cell-substrate adhesion. Proc Natl Acad Sci USA 90: 11177-11181, 1993.
18. Yang C, Chang J, Gorospe M and Passaniti A: Protein tyrosine phosphatase regulation of endothelial cell apoptosis and differentiation. Cell Growth Differ 7: 161-171, 1996.
19. Frisch SM, Vuori K, Ruoslahti E and Chan-Hui P-Y: Control of adhesion-dependent cell survival by focal adhesion kinase. J Cell Biol 134: 793-799, 1996.
20. Song Q, Wei T, Lees-Miller S, Alnemri E, Watters D and Lavin MF: Resistance of actin to cleavage during apoptosis. Proc Natl Acad Sci USA 94: 157-162, 1997.
21. Kaufmann SH: Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin and other cytotoxic anticancer drugs: A cautionary note. Cancer Res 49: 5870-5878, 1989.
22. Lazebnik YA, Kaufmann SH, Desnoyers S, Poirier GG and Earnshaw WC: Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 371: 346-347, 1994.
23. Martin SJ, O'Brien GA, Nishioka WK, McGahon AJ, Mahboubi A, Saido TC and Green DR: Proteolysis of fodrin (non-erythroid spectrin) during apoptosis. J Biol Chem 270: 6425-6428, 1995.
24. Na S, Chuang T-H, Cunningham A, Turi TG, Hanke JH, Bokoch GM and Danley DE: D4-GDI, a substrate of CPP32, is proteolyzed during Fas-induced apoptosis. J Biol Chem 271: 11209-11213, 1996.
25. Martin SJ and Green DR: Protease activation during apoptosis: Death by a thousand cuts? Cell 82: 349-352, 1995.
26. Xu L-h, Owens LV, Sturge GC, Yang X, Liu ET, Craven RJ and Cance WG: Attenuation of the expression of the focal adhesion kinase induces apoptosis in tumor cells. Cell Growth Differ 7: 413-418, 1996.
27. Coll J-L, Ben-Ze'ev A, Ezzell RM, Rodriguez Fernández JL, Baribault H, Oshima RG and Adamson ED: Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion. Proc Natl Acad Sci USA 92: 9161-9165, 1995.