-
1
-
-
0032966238
-
Positive feedback interactions between microtubule and actin dynamics during cell motility
-
Waterman-Storer CM Positive feedback interactions between microtubule and actin dynamics during cell motility. Curr Opin Cell Biol. 11:1999;61-67.
-
(1999)
Curr Opin Cell Biol
, vol.11
, pp. 61-67
-
-
Waterman-Storer, C.M.1
-
3
-
-
0033005733
-
Accessory protein regulation of microtubule dynamics throughout the cell cycle
-
Cassimeris L Accessory protein regulation of microtubule dynamics throughout the cell cycle. Curr Opin Cell Biol. 11:1999;134-141.
-
(1999)
Curr Opin Cell Biol
, vol.11
, pp. 134-141
-
-
Cassimeris, L.1
-
4
-
-
0028173688
-
Involvement of profilin in the actin-based motility of L. monocytogenes in cells and in cell-free extracts
-
Theriot JA, Rosenblatt J, Portnoy DA, Goldschmidt-Clermont PJ, Mitchison TJ Involvement of profilin in the actin-based motility of L. monocytogenes in cells and in cell-free extracts. Cell. 76:1994;505-517.
-
(1994)
Cell
, vol.76
, pp. 505-517
-
-
Theriot, J.A.1
Rosenblatt, J.2
Portnoy, D.A.3
Goldschmidt-Clermont, P.J.4
Mitchison, T.J.5
-
5
-
-
0032528059
-
Interactions of Listeria monocytogenes with mammalian cells during entry and actin-based movement: Bacterial factors, cellular ligands and signaling
-
Cossart P, Lecuit M Interactions of Listeria monocytogenes with mammalian cells during entry and actin-based movement: bacterial factors, cellular ligands and signaling. EMBO J. 17:1998;3797-3806.
-
(1998)
EMBO J
, vol.17
, pp. 3797-3806
-
-
Cossart, P.1
Lecuit, M.2
-
7
-
-
0031021153
-
Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes
-
The Arp2/3 complex was shown to induce actin polymerization on the surface of Listeria. Two alternative models for the role of the Arp2/3 complex in action based motility of Listeria are discussed.
-
Welch MD, Iwamatsu A, Mitchison TJ Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes. Nature. 385:1997;265-269. The Arp2/3 complex was shown to induce actin polymerization on the surface of Listeria. Two alternative models for the role of the Arp2/3 complex in action based motility of Listeria are discussed.
-
(1997)
Nature
, vol.385
, pp. 265-269
-
-
Welch, M.D.1
Iwamatsu, A.2
Mitchison, T.J.3
-
8
-
-
0032479578
-
Interaction of human Arp2/3 complex and the Listeria monocytogenes ActA protein in actin filament nucleation
-
Using purified protein from human platelets the authors demonstrate that the Arp2/3 complex accelerates the nucleation of actin polymerization in vitro. The actin nucleation activity of the Arp2/3 complex is stimulated 50-fold by the amino-terminal domain of the Listeria ActA protein.
-
Welch MD, Rosenblatt J, Skole J, Portnoy DA, Mitchison TJ Interaction of human Arp2/3 complex and the Listeria monocytogenes ActA protein in actin filament nucleation. Science. 281:1998;105-108. Using purified protein from human platelets the authors demonstrate that the Arp2/3 complex accelerates the nucleation of actin polymerization in vitro. The actin nucleation activity of the Arp2/3 complex is stimulated 50-fold by the amino-terminal domain of the Listeria ActA protein.
-
(1998)
Science
, vol.281
, pp. 105-108
-
-
Welch, M.D.1
Rosenblatt, J.2
Skole, J.3
Portnoy, D.A.4
Mitchison, T.J.5
-
9
-
-
0032500057
-
Actin branches out
-
Machesky L, Way M Actin branches out. Nature. 394:1998;125-126.
-
(1998)
Nature
, vol.394
, pp. 125-126
-
-
Machesky, L.1
Way, M.2
-
10
-
-
0032505113
-
Actin cytoskeleton: The Arp2/3 complex gets to the point
-
Zigmond SH Actin cytoskeleton: the Arp2/3 complex gets to the point. Curr Biol. 8:1998;R654.
-
(1998)
Curr Biol
, vol.8
, pp. 654
-
-
Zigmond, S.H.1
-
11
-
-
0033040628
-
The Arp2/3 complex: A multifunctional actin organizer
-
Machesky LM, Gould KL The Arp2/3 complex: a multifunctional actin organizer. Curr Opin Cell Biol. 11:1999;117-121.
-
(1999)
Curr Opin Cell Biol
, vol.11
, pp. 117-121
-
-
Machesky, L.M.1
Gould, K.L.2
-
12
-
-
0032568650
-
The interaction of Arp2/3 complex with actin: Nucleation, high affinity pointed end capping, and formation of branching networks of filaments
-
Using purified protein from Acanthameoba the authors examine the effects of the Arp2/3 complex on actin dynamics in vitro. On the basis of their observations that the complex weakly nucleates actin assembly, caps pointed ends of actin filaments and induces filament branching, the authors suggest a new model for actin assembly at the leading edge of cells that they term dendritic nucleation.
-
Mullins DR, Heuser JA, Pollard TD The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments. Proc Natl Acad Sci USA. 95:1998;6181-6186. Using purified protein from Acanthameoba the authors examine the effects of the Arp2/3 complex on actin dynamics in vitro. On the basis of their observations that the complex weakly nucleates actin assembly, caps pointed ends of actin filaments and induces filament branching, the authors suggest a new model for actin assembly at the leading edge of cells that they term dendritic nucleation.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6181-6186
-
-
Mullins, D.R.1
Heuser, J.A.2
Pollard, T.D.3
-
13
-
-
0030843484
-
Actin depolymerizing factor (ADF/cofilin) enhances the rate of filament turnover: Implication in actin-based motility
-
Addition of actin depolymerizing factor (ADF) from Arabidopsis to Xenopus egg extracts enhances the rate of Listeria motility and shortens actin tails. The authors propose these effects are not mediated by actin filament severing.
-
Carlier M-F, Laurent V, Santolini J, Melki R, Didry D, Xia G-X, Hong Y, Chua N-H, Pantaloni D Actin depolymerizing factor (ADF/cofilin) enhances the rate of filament turnover: implication in actin-based motility. J Cell Biol. 136:1997;1307-1323. Addition of actin depolymerizing factor (ADF) from Arabidopsis to Xenopus egg extracts enhances the rate of Listeria motility and shortens actin tails. The authors propose these effects are not mediated by actin filament severing.
-
(1997)
J Cell Biol
, vol.136
, pp. 1307-1323
-
-
Carlier, M.-F.1
Laurent, V.2
Santolini, J.3
Melki, R.4
Didry, D.5
Xia, G.-X.6
Hong, Y.7
Chua, N.-H.8
Pantaloni, D.9
-
14
-
-
0030821155
-
Xenopus actin depolymerizing factor/cofilin (XAC) is responsible for the turnover of actin filaments in Listeria monocytogenes tails
-
Depletion of actin depolymerizing factor (ADF)/cofilin from Xenopus egg extracts resulted in long Listeria actin tails while addition of protein to depleted extracts restored normal actin tail lengths. In contrast depletion of the actin filament severing protein gelsolin had no effect on Listeria actin tail length. The authors conclude that ADF/cofilin and not gelsolin is the main protein responsible for actin filament depolymerization in vivo.
-
Rosenblatt J, Agnew BJ, Abe H, Bamburg JR, Mitchison TJ Xenopus actin depolymerizing factor/cofilin (XAC) is responsible for the turnover of actin filaments in Listeria monocytogenes tails. J Cell Biol. 136:1997;1323-1332. Depletion of actin depolymerizing factor (ADF)/cofilin from Xenopus egg extracts resulted in long Listeria actin tails while addition of protein to depleted extracts restored normal actin tail lengths. In contrast depletion of the actin filament severing protein gelsolin had no effect on Listeria actin tail length. The authors conclude that ADF/cofilin and not gelsolin is the main protein responsible for actin filament depolymerization in vivo.
-
(1997)
J Cell Biol
, vol.136
, pp. 1323-1332
-
-
Rosenblatt, J.1
Agnew, B.J.2
Abe, H.3
Bamburg, J.R.4
Mitchison, T.J.5
-
15
-
-
0030798735
-
Accelerating on a treadmill: ADF/cofilin promotes rapid turnover in the dynamic cytoskeleton
-
Theriot JA Accelerating on a treadmill: ADF/cofilin promotes rapid turnover in the dynamic cytoskeleton. J Cell Biol. 136:1997;1165-1168.
-
(1997)
J Cell Biol
, vol.136
, pp. 1165-1168
-
-
Theriot, J.A.1
-
16
-
-
0031887131
-
How ADF/cofilin depolymerizes actin filaments
-
MacIver SK How ADF/cofilin depolymerizes actin filaments. Curr Opin Cell Biol. 10:1998;140-144.
-
(1998)
Curr Opin Cell Biol
, vol.10
, pp. 140-144
-
-
MacIver, S.K.1
-
17
-
-
0032559362
-
Rho GTPases and the actin cytoskeleton
-
Hall A Rho GTPases and the actin cytoskeleton. Science. 279:1998;509-514.
-
(1998)
Science
, vol.279
, pp. 509-514
-
-
Hall, A.1
-
18
-
-
0030968580
-
Rho GTPases and signaling networks
-
Van Aelst L, D'Souza-Schorey C Rho GTPases and signaling networks. Genes Dev. 11:1997;2295-2322.
-
(1997)
Genes Dev
, vol.11
, pp. 2295-2322
-
-
Van Aelst, L.1
D'Souza-Schorey, C.2
-
19
-
-
0028981496
-
Actin-based movement of Listeria monocytogenes: Actin assembly results from the local maintenance of uncapped filament barbed ends at the bacterium surface
-
Marchand JB, Moreau P, Paoletti A, Cossart P, Carlier MF, Pantaloni D Actin-based movement of Listeria monocytogenes: actin assembly results from the local maintenance of uncapped filament barbed ends at the bacterium surface. J Cell Biol. 130:1995;331-343.
-
(1995)
J Cell Biol
, vol.130
, pp. 331-343
-
-
Marchand, J.B.1
Moreau, P.2
Paoletti, A.3
Cossart, P.4
Carlier, M.F.5
Pantaloni, D.6
-
20
-
-
0032523955
-
Cdc42 is required for membrane dependent actin polymerization in vitro
-
An actin-based motility of endogenous vesicles can be stimulated by addition of vanadate or GTPγS to Xenopus egg extracts. The vesicle motility is shown to be dependent on the small GTPase Cdc42, unlike Listeria actin-based motility.
-
Moreau V, Way M Cdc42 is required for membrane dependent actin polymerization in vitro. FEBS Lett. 427:1998;353-356. An actin-based motility of endogenous vesicles can be stimulated by addition of vanadate or GTPγS to Xenopus egg extracts. The vesicle motility is shown to be dependent on the small GTPase Cdc42, unlike Listeria actin-based motility.
-
(1998)
FEBS Lett
, vol.427
, pp. 353-356
-
-
Moreau, V.1
Way, M.2
-
21
-
-
0030849454
-
Regulation of actin polymerization in cell-free systems by GTPγS and Cdc42
-
Zigmond SH, Joyce M, Borleis J, Bokoch GM, Devreotes PN Regulation of actin polymerization in cell-free systems by GTPγS and Cdc42. J Cell Biol. 138:1997;363-374.
-
(1997)
J Cell Biol
, vol.138
, pp. 363-374
-
-
Zigmond, S.H.1
Joyce, M.2
Borleis, J.3
Bokoch, G.M.4
Devreotes, P.N.5
-
22
-
-
0032563603
-
Mechanism of Cdc42-induced actin polymerization in neutrophil extracts
-
Using the cell free system established earlier [21], the authors dissect the mechanism of Cdc42 dependent actin polymerization. Their data suggest that Cdc42 stimulated actin polymerization occurs through the formation of new free barbed ends and their subsequent elongation.
-
Zigmond SH, Joyce M, Yang K, Brown M, Huang, Pring M Mechanism of Cdc42-induced actin polymerization in neutrophil extracts. J Cell Biol. 142:1998;1001-1012. Using the cell free system established earlier [21], the authors dissect the mechanism of Cdc42 dependent actin polymerization. Their data suggest that Cdc42 stimulated actin polymerization occurs through the formation of new free barbed ends and their subsequent elongation.
-
(1998)
J Cell Biol
, vol.142
, pp. 1001-1012
-
-
Zigmond, S.H.1
Joyce, M.2
Yang, K.3
Brown, M.4
Huang5
Pring, M.6
-
23
-
-
0031863308
-
GTPγS-induced actin polymerisation in vitro: ATP- And phosphoinositide-independent signalling via Rho-family proteins and a plasma membrane-associated guanine nucleotide exchange factor
-
Katanaev VL, Wymann MP GTPγS-induced actin polymerisation in vitro: ATP- and phosphoinositide-independent signalling via Rho-family proteins and a plasma membrane-associated guanine nucleotide exchange factor. J Cell Sci. 111:1998;1583-1594.
-
(1998)
J Cell Sci
, vol.111
, pp. 1583-1594
-
-
Katanaev, V.L.1
Wymann, M.P.2
-
24
-
-
0032498854
-
Corequirement of specific phosphoinositides and small GTP-binding protein Cdc42 in inducing actin assembly in Xenopus egg extracts
-
Using vesicles prepared from purified phospholipids, the authors show that both phosphoinositides and the small GTPase Cdc42 are required to induce actin assembly in Xenopus egg extracts.
-
Ma L, Cantley LC, Janmey PA, Kirschner MW Corequirement of specific phosphoinositides and small GTP-binding protein Cdc42 in inducing actin assembly in Xenopus egg extracts. J Cell Biol. 140:1998;1125-1136. Using vesicles prepared from purified phospholipids, the authors show that both phosphoinositides and the small GTPase Cdc42 are required to induce actin assembly in Xenopus egg extracts.
-
(1998)
J Cell Biol
, vol.140
, pp. 1125-1136
-
-
Ma, L.1
Cantley, L.C.2
Janmey, P.A.3
Kirschner, M.W.4
-
26
-
-
0032006024
-
Microtubule dynamics in living cells
-
Joshi HC Microtubule dynamics in living cells. Curr Opin Cell Biol. 10:1998;35-44.
-
(1998)
Curr Opin Cell Biol
, vol.10
, pp. 35-44
-
-
Joshi, H.C.1
-
27
-
-
0020622592
-
Formation in vitro of sperm pronuclei and mitotic chromosomes induced by amphibian ooplasmic components
-
Lohka MJ, Masui Y Formation in vitro of sperm pronuclei and mitotic chromosomes induced by amphibian ooplasmic components. Science. 220:1983;719-721.
-
(1983)
Science
, vol.220
, pp. 719-721
-
-
Lohka, M.J.1
Masui, Y.2
-
28
-
-
0021176610
-
Roles of cytosol and cytoplasmic particles in nuclear envelope assembly and sperm pronuclear formation in cell-free preparations from amphibian eggs
-
Lohka MJ, Masui Y Roles of cytosol and cytoplasmic particles in nuclear envelope assembly and sperm pronuclear formation in cell-free preparations from amphibian eggs. J Cell Biol. 98:1984;1222-1230.
-
(1984)
J Cell Biol
, vol.98
, pp. 1222-1230
-
-
Lohka, M.J.1
Masui, Y.2
-
29
-
-
0022415960
-
Induction of nuclear envelope breakdown, chromosome condensation, and spindle formation in cell-free extracts
-
Lohka MJ, Maller JL Induction of nuclear envelope breakdown, chromosome condensation, and spindle formation in cell-free extracts. J Cell Biol. 101:1985;518-523.
-
(1985)
J Cell Biol
, vol.101
, pp. 518-523
-
-
Lohka, M.J.1
Maller, J.L.2
-
30
-
-
0029836330
-
Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extract
-
Heald R, Tournebize R, Blank T, Sandaltzopoulos R, Becker P, Hyman A, Karsenti E Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extract. Nature. 382:1996;420-425.
-
(1996)
Nature
, vol.382
, pp. 420-425
-
-
Heald, R.1
Tournebize, R.2
Blank, T.3
Sandaltzopoulos, R.4
Becker, P.5
Hyman, A.6
Karsenti, E.7
-
31
-
-
0030748898
-
Mitotic chromatin regulates phosphorylation of Stathmin/Op18
-
Andersen SS, Ashford AJ, Tournebize R, Gavet O, Sobel A, Hyman AA, Karsenti E Mitotic chromatin regulates phosphorylation of Stathmin/Op18. Nature. 389:1997;640-643.
-
(1997)
Nature
, vol.389
, pp. 640-643
-
-
Andersen, S.S.1
Ashford, A.J.2
Tournebize, R.3
Gavet, O.4
Sobel, A.5
Hyman, A.A.6
Karsenti, E.7
-
32
-
-
0022201052
-
Properties of the kinetochore in vitro. II- Microtubule capture and ATP-dependent translocation
-
Mitchison TJ, Kirschner MW Properties of the kinetochore in vitro. II- Microtubule capture and ATP-dependent translocation. J Cell Biol. 101:1985;766-777.
-
(1985)
J Cell Biol
, vol.101
, pp. 766-777
-
-
Mitchison, T.J.1
Kirschner, M.W.2
-
33
-
-
0022246298
-
Properties of the kinetochore in vitro. I- Microtubule nucleation and tubulin binding
-
Mitchison TJ, Kirschner MW Properties of the kinetochore in vitro. I- Microtubule nucleation and tubulin binding. J Cell Biol. 101:1985;755-765.
-
(1985)
J Cell Biol
, vol.101
, pp. 755-765
-
-
Mitchison, T.J.1
Kirschner, M.W.2
-
34
-
-
0028833289
-
A new role for motor proteins as couplers to depolymerizing microtubules
-
Desai A, Mitchison TJ A new role for motor proteins as couplers to depolymerizing microtubules. J Cell Biol. 128:1995;1-4.
-
(1995)
J Cell Biol
, vol.128
, pp. 1-4
-
-
Desai, A.1
Mitchison, T.J.2
-
35
-
-
0030785518
-
A method that allows the assembly of kinetochore components onto chromosomes condensed in clarified Xenopus egg extracts
-
This paper describes an in vitro assembly assay that should facilitate the identification of further kinetochore associated proteins.
-
Desai A, Deacon TJ, Walczak CE, Mitchison TJ A method that allows the assembly of kinetochore components onto chromosomes condensed in clarified Xenopus egg extracts. Proc Natl Acad Sci USA. 94:1997;12378-12383. This paper describes an in vitro assembly assay that should facilitate the identification of further kinetochore associated proteins.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 12378-12383
-
-
Desai, A.1
Deacon, T.J.2
Walczak, C.E.3
Mitchison, T.J.4
-
36
-
-
0033534575
-
Kin I kinesins are microtubule destabilizing enzymes
-
XKCM1 and XKIF2 two kinesin related proteins are shown to depolymerize microtubules by binding to polymer ends and destabilizing tubulin dimers in an ATP-dependent fashion.
-
Desai A, Verma S, Mitchison TJ, Walczak CE Kin I kinesins are microtubule destabilizing enzymes. Cell. 96:1999;69-78. XKCM1 and XKIF2 two kinesin related proteins are shown to depolymerize microtubules by binding to polymer ends and destabilizing tubulin dimers in an ATP-dependent fashion.
-
(1999)
Cell
, vol.96
, pp. 69-78
-
-
Desai, A.1
Verma, S.2
Mitchison, T.J.3
Walczak, C.E.4
-
37
-
-
0031694617
-
The dynamic behavior of individual microtubules associated with chromosomes in vitro
-
This paper describes the development of an in vitro assay with which to study the coupling of a chromosome to the polymerizing and depolymerizing end of microtubules.
-
Hunt AJ, McIntosh JR The dynamic behavior of individual microtubules associated with chromosomes in vitro. Mol Biol Cell. 9:1998;2857-2871. This paper describes the development of an in vitro assay with which to study the coupling of a chromosome to the polymerizing and depolymerizing end of microtubules.
-
(1998)
Mol Biol Cell
, vol.9
, pp. 2857-2871
-
-
Hunt, A.J.1
McIntosh, J.R.2
-
38
-
-
0030921846
-
Kinetochores distinguish GTP from GDP forms of the microtubule lattice
-
Using kinetochores that have been reconstituted from the yeast Saccharomyces cerevisiae, the authors demonstrate that they are able to distinguish the different structural states of a GTP- versus a GDP-microtubule lattice.
-
Severin FF, Sorger PK, Hyman AA Kinetochores distinguish GTP from GDP forms of the microtubule lattice. Nature. 388:1997;888-891. Using kinetochores that have been reconstituted from the yeast Saccharomyces cerevisiae, the authors demonstrate that they are able to distinguish the different structural states of a GTP- versus a GDP-microtubule lattice.
-
(1997)
Nature
, vol.388
, pp. 888-891
-
-
Severin, F.F.1
Sorger, P.K.2
Hyman, A.A.3
-
40
-
-
0029128472
-
Membrane/microtubule tip attachement complexes (TACs) allow the assembly dynamics of plus ends to push and pull membranes into tubulovesicular networks in interphase Xenopus egg extracts
-
Waterman-Storer CM, Gregory J, Parsons SF, Salmon ED Membrane/microtubule tip attachement complexes (TACs) allow the assembly dynamics of plus ends to push and pull membranes into tubulovesicular networks in interphase Xenopus egg extracts. J Cell Biol. 130:1995;1161-1169.
-
(1995)
J Cell Biol
, vol.130
, pp. 1161-1169
-
-
Waterman-Storer, C.M.1
Gregory, J.2
Parsons, S.F.3
Salmon, E.D.4
-
41
-
-
0032474825
-
Endoplasmic reticulum membrane tubules are distributed by microtubules in living cells using three distinct mechanisms
-
Waterman-Storer CM, Salmon ED Endoplasmic reticulum membrane tubules are distributed by microtubules in living cells using three distinct mechanisms. Curr Biol. 8:1998;798-806.
-
(1998)
Curr Biol
, vol.8
, pp. 798-806
-
-
Waterman-Storer, C.M.1
Salmon, E.D.2
-
42
-
-
0031931095
-
A role for microtubule dynamics in phagosome movement
-
•], it has been possible to demonstrate that phagosomes are able to bind plus ends of microtubules. In addition to a microtubule-based motor movement [43], early phagosomes are also able to move using microtubule dynamics.
-
•], it has been possible to demonstrate that phagosomes are able to bind plus ends of microtubules. In addition to a microtubule-based motor movement [43], early phagosomes are also able to move using microtubule dynamics.
-
(1998)
J Cell Sci
, vol.111
, pp. 303-312
-
-
Blocker, A.1
Griffiths, G.2
Olivo, J.C.3
Hyman, A.A.4
Severin, F.F.5
-
43
-
-
0030961946
-
Molecular requirements for bi-directional movement of phagosomes along microtubules
-
Blocker A, Severin FF, Burkhardt JK, Bingham JB, Yu H, Olivo JC, Schroer TA, Hyman AA, Griffiths G Molecular requirements for bi-directional movement of phagosomes along microtubules. J Cell Biol. 137:1997;113-129.
-
(1997)
J Cell Biol
, vol.137
, pp. 113-129
-
-
Blocker, A.1
Severin, F.F.2
Burkhardt, J.K.3
Bingham, J.B.4
Yu, H.5
Olivo, J.C.6
Schroer, T.A.7
Hyman, A.A.8
Griffiths, G.9
-
44
-
-
0020586332
-
Movement of myosin-coated fluorescent beads on actin cables in vitro
-
Sheetz MP, Spudich JA Movement of myosin-coated fluorescent beads on actin cables in vitro. Nature. 303:1983;31-35.
-
(1983)
Nature
, vol.303
, pp. 31-35
-
-
Sheetz, M.P.1
Spudich, J.A.2
-
45
-
-
0001675681
-
Fluorescent actin filaments move on myosin fixed to a glass surface
-
Kron SJ, Spudich JA Fluorescent actin filaments move on myosin fixed to a glass surface. Proc Natl Acad Sci USA. 83:1986;6272-6276.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 6272-6276
-
-
Kron, S.J.1
Spudich, J.A.2
-
46
-
-
0021849732
-
Organelle, bead, and microtubule translocations promoted by soluble factors from squid giant axon
-
Vale RD, Schnapp BJ, Reese TS, Sheetz MP Organelle, bead, and microtubule translocations promoted by soluble factors from squid giant axon. Cell. 40:1985;559-569.
-
(1985)
Cell
, vol.40
, pp. 559-569
-
-
Vale, R.D.1
Schnapp, B.J.2
Reese, T.S.3
Sheetz, M.P.4
-
47
-
-
0022385727
-
Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility
-
Vale RD, Reese TS, Sheetz MP Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility. Cell. 42:1985;39-50.
-
(1985)
Cell
, vol.42
, pp. 39-50
-
-
Vale, R.D.1
Reese, T.S.2
Sheetz, M.P.3
-
48
-
-
0031977198
-
Human myosin-IXb is a mechanochemically active motor and a GAP for Rho
-
Post PL, Bokoch GM, Mooseker MS Human myosin-IXb is a mechanochemically active motor and a GAP for Rho. J Cell Sci. 111:1998;941-950.
-
(1998)
J Cell Sci
, vol.111
, pp. 941-950
-
-
Post, P.L.1
Bokoch, G.M.2
Mooseker, M.S.3
-
49
-
-
0031858040
-
A developmentally regulated kinesin-related motor protein from Dictyostelium discodeum
-
de Hostos EL, McCaffrey G, Sucgang R, Pierce DW, Vale RD A developmentally regulated kinesin-related motor protein from Dictyostelium discodeum. Mol Biol Cell. 9:1998;2093-2106.
-
(1998)
Mol Biol Cell
, vol.9
, pp. 2093-2106
-
-
De Hostos, E.L.1
McCaffrey, G.2
Sucgang, R.3
Pierce, D.W.4
Vale, R.D.5
-
50
-
-
0033004145
-
Cytoplasmic dynein and dynactin in cell division and intracellular transport
-
Karki S, Holzbaur ELF Cytoplasmic dynein and dynactin in cell division and intracellular transport. Curr Opin Cell Biol. 11:1999;45-53.
-
(1999)
Curr Opin Cell Biol
, vol.11
, pp. 45-53
-
-
Karki, S.1
Holzbaur, E.L.F.2
-
51
-
-
0031105358
-
Movement of nuclei along microtubules in Xenopus egg extracts
-
This paper describes the development of an in vitro system to study the molecular basis of the movement of nuclei on microtubules that is dependent on dynein.
-
Reinsch S, Karsenti E Movement of nuclei along microtubules in Xenopus egg extracts. Curr Biol. 7:1997;211-214. This paper describes the development of an in vitro system to study the molecular basis of the movement of nuclei on microtubules that is dependent on dynein.
-
(1997)
Curr Biol
, vol.7
, pp. 211-214
-
-
Reinsch, S.1
Karsenti, E.2
-
52
-
-
0028595709
-
Involvement of microtubule motors in basolateral and apical transport in kidney cells
-
Lafont F, Burkhardt JK, Simons K Involvement of microtubule motors in basolateral and apical transport in kidney cells. Nature. 372:1994;801-803.
-
(1994)
Nature
, vol.372
, pp. 801-803
-
-
Lafont, F.1
Burkhardt, J.K.2
Simons, K.3
-
53
-
-
0030780090
-
Molecular motors and a spectrin matrix associate with Golgi membranes in vitro
-
The movement of Golgi stacks along microtubules is reconstituted in vitro. This minus-end directed movement is dependent on dynein, which binds to regions of Golgi stacks that are destined to bud.
-
Fath KR, Trimbur GM, Burgess DR Molecular motors and a spectrin matrix associate with Golgi membranes in vitro. J Cell Biol. 139:1997;1169-1181. The movement of Golgi stacks along microtubules is reconstituted in vitro. This minus-end directed movement is dependent on dynein, which binds to regions of Golgi stacks that are destined to bud.
-
(1997)
J Cell Biol
, vol.139
, pp. 1169-1181
-
-
Fath, K.R.1
Trimbur, G.M.2
Burgess, D.R.3
-
54
-
-
0030479303
-
Centractin (ARP1) associates with spectrin revealing a potential mechanism to link dynactin to intracellular organelles
-
Holleran EA, Tokito MK, Karki S, Holtzbaur ELF Centractin (ARP1) associates with spectrin revealing a potential mechanism to link dynactin to intracellular organelles. J Cell Biol. 135:1996;1815-1829.
-
(1996)
J Cell Biol
, vol.135
, pp. 1815-1829
-
-
Holleran, E.A.1
Tokito, M.K.2
Karki, S.3
Holtzbaur, E.L.F.4
-
55
-
-
0031780351
-
In vitro microtubule based organelle transport in wild-type Dictyostelium and cells overexpressing a truncated dynein heavy chain
-
This paper described the in vitro reconstitution of vesicle transport along microtubules in Dictyostelium discoideum extracts. Using a mutant overexpressing a carboxy-terminal fragment of the cytoplasmic dynein heavy chain, the authors show an alteration in the minus end directed movement of vesicles that is probably due to impaired membrane-microtubule interactions.
-
Pollock N, Koonce MP, de Hostos EL, Vale RD In vitro microtubule based organelle transport in wild-type Dictyostelium and cells overexpressing a truncated dynein heavy chain. Cell Motil Cytoskeleton. 40:1998;304-314. This paper described the in vitro reconstitution of vesicle transport along microtubules in Dictyostelium discoideum extracts. Using a mutant overexpressing a carboxy-terminal fragment of the cytoplasmic dynein heavy chain, the authors show an alteration in the minus end directed movement of vesicles that is probably due to impaired membrane-microtubule interactions.
-
(1998)
Cell Motil Cytoskeleton
, vol.40
, pp. 304-314
-
-
Pollock, N.1
Koonce, M.P.2
De Hostos, E.L.3
Vale, R.D.4
-
56
-
-
0031664962
-
In vitro reconstitution of microtubule plus end-directed, GTPγS-sensitive motility of Golgi membranes
-
Using purified Golgi membranes mixed with cytosol and microtubules, the authors described an in vitro plus end directed movement sensitive to GTPγS. They conclude that Golgi membrane transport is mediated by a kinesin and regulated by an unknown GTPase.
-
Fullerton AT, Bau MY, Conrad PA, Bloom GS In vitro reconstitution of microtubule plus end-directed, GTPγS-sensitive motility of Golgi membranes. Mol Biol Cell. 9:1998;2699-2714. Using purified Golgi membranes mixed with cytosol and microtubules, the authors described an in vitro plus end directed movement sensitive to GTPγS. They conclude that Golgi membrane transport is mediated by a kinesin and regulated by an unknown GTPase.
-
(1998)
Mol Biol Cell
, vol.9
, pp. 2699-2714
-
-
Fullerton, A.T.1
Bau, M.Y.2
Conrad, P.A.3
Bloom, G.S.4
-
57
-
-
0032559349
-
Unconventional myosins in cell movement, membrane traffic, and signal transduction
-
Mermall V, Post PL, Mooseker MS Unconventional myosins in cell movement, membrane traffic, and signal transduction. Science. 279:1998;527-533.
-
(1998)
Science
, vol.279
, pp. 527-533
-
-
Mermall, V.1
Post, P.L.2
Mooseker, M.S.3
-
58
-
-
0032005265
-
Myosins: Matching functions with motors
-
Baker JP, Titus MA Myosins: matching functions with motors. Curr Opin Cell Biol. 10:1998;80-86.
-
(1998)
Curr Opin Cell Biol
, vol.10
, pp. 80-86
-
-
Baker, J.P.1
Titus, M.A.2
-
59
-
-
0032576778
-
Myosin cooperates with microtubule motors during organelle transport in melanophores
-
This paper described in vitro studies of the first well defined organelle (melanosome) using in concert all three motor-based systems, namely plus-end and minus-end directed microtubule motors as well as myosin for its proper distribution in melanophores.
-
Rogers SL, Gelfand VI Myosin cooperates with microtubule motors during organelle transport in melanophores. Curr Biol. 8:1998;161-164. This paper described in vitro studies of the first well defined organelle (melanosome) using in concert all three motor-based systems, namely plus-end and minus-end directed microtubule motors as well as myosin for its proper distribution in melanophores.
-
(1998)
Curr Biol
, vol.8
, pp. 161-164
-
-
Rogers, S.L.1
Gelfand, V.I.2
-
60
-
-
0032576766
-
Functional coordination of microtubule-based and actin-based motility in melanophores
-
The requirement of microtubule- and actin-based motors for the movement of melanosomes in vivo is described.
-
Rodionov VI, Hope AJ, Svitkina TM, Borisy GG Functional coordination of microtubule-based and actin-based motility in melanophores. Curr Biol. 8:1998;165-168. The requirement of microtubule- and actin-based motors for the movement of melanosomes in vivo is described.
-
(1998)
Curr Biol
, vol.8
, pp. 165-168
-
-
Rodionov, V.I.1
Hope, A.J.2
Svitkina, T.M.3
Borisy, G.G.4
-
61
-
-
0031819385
-
Vesicle-associated brain myosin-V can be activated to catalyse actin-based transport
-
This paper directly shows the functionality of myosin V in the actin based motility of vesicles in vitro. Data are presented to suggest that myosin V is tightly bound to the vesicle and regulated by additional factors which remain to be identified.
-
Evans LL, Lee AJ, Bridgman PC, Mooseker MS Vesicle-associated brain myosin-V can be activated to catalyse actin-based transport. J Cell Sci. 111:1998;2055-2066. This paper directly shows the functionality of myosin V in the actin based motility of vesicles in vitro. Data are presented to suggest that myosin V is tightly bound to the vesicle and regulated by additional factors which remain to be identified.
-
(1998)
J Cell Sci
, vol.111
, pp. 2055-2066
-
-
Evans, L.L.1
Lee, A.J.2
Bridgman, P.C.3
Mooseker, M.S.4
-
63
-
-
0026009462
-
Purified kinesin promotes vesicle motility and induces active sliding between microtubules in vitro
-
Urrutia R, McNiven MA, Albanesi JP, Murphy DB, Kachar B Purified kinesin promotes vesicle motility and induces active sliding between microtubules in vitro. Proc Natl Acad Sci USA. 88:1991;6701-6705.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 6701-6705
-
-
Urrutia, R.1
McNiven, M.A.2
Albanesi, J.P.3
Murphy, D.B.4
Kachar, B.5
-
64
-
-
0026071835
-
Taxol-induced microtubules asters in mitotic extracts of Xenopus eggs: Requirement for phosphorylated factors and cytoplasmic dynein
-
Verde F, Berrez JM, Antony C, Karsenti E Taxol-induced microtubules asters in mitotic extracts of Xenopus eggs: requirement for phosphorylated factors and cytoplasmic dynein. J Cell Biol. 112:1991;1177-1187.
-
(1991)
J Cell Biol
, vol.112
, pp. 1177-1187
-
-
Verde, F.1
Berrez, J.M.2
Antony, C.3
Karsenti, E.4
-
65
-
-
0030059247
-
Morphogenetic properties of microtubules and mitotic spindle assembly
-
Hyman AA, Karsenti E Morphogenetic properties of microtubules and mitotic spindle assembly. Cell. 84:1996;401-410.
-
(1996)
Cell
, vol.84
, pp. 401-410
-
-
Hyman, A.A.1
Karsenti, E.2
-
66
-
-
0037813094
-
Self-organization of microtubules and motors
-
This paper describes a variety of self-organized structures obtained in vitro by mixing purified microtubules and multiheaded kinesin.
-
Nédélec FJ, Surrey T, Maggs AC, Leibler S Self-organization of microtubules and motors. Nature. 389:1997;305-308. This paper describes a variety of self-organized structures obtained in vitro by mixing purified microtubules and multiheaded kinesin.
-
(1997)
Nature
, vol.389
, pp. 305-308
-
-
Nédélec, F.J.1
Surrey, T.2
Maggs, A.C.3
Leibler, S.4
-
67
-
-
0031809137
-
Focusing on spindle poles
-
Compton DA Focusing on spindle poles. J Cell Sci. 111:1998;1477-1481.
-
(1998)
J Cell Sci
, vol.111
, pp. 1477-1481
-
-
Compton, D.A.1
-
68
-
-
13144251122
-
A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bipolarity
-
Using the assay described by [30], the authors described the role of several microtubule-based motors in spindle assembly. They show that the establishment of the spindle bipolarity requires multiple motor activities.
-
Walczak CE, Vernos I, Mitchison TJ, Karsenti E, Heald R A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bipolarity. Curr Biol. 8:1998;903-913. Using the assay described by [30], the authors described the role of several microtubule-based motors in spindle assembly. They show that the establishment of the spindle bipolarity requires multiple motor activities.
-
(1998)
Curr Biol
, vol.8
, pp. 903-913
-
-
Walczak, C.E.1
Vernos, I.2
Mitchison, T.J.3
Karsenti, E.4
Heald, R.5
-
69
-
-
0030961046
-
Mitotic spindle poles are organized by structural and motor proteins in addition to centrosomes
-
Gaglio T, Dionne MA, Compton DA Mitotic spindle poles are organized by structural and motor proteins in addition to centrosomes. J Cell Biol. 138:1997;1055-1066.
-
(1997)
J Cell Biol
, vol.138
, pp. 1055-1066
-
-
Gaglio, T.1
Dionne, M.A.2
Compton, D.A.3
-
70
-
-
0030751640
-
Spindle assembly in Xenopus egg extracts: Respective roles of centrosomes and microtubule self-organization
-
Heald R, Tournebize R, Habermann A, Karsenti E, Hyman A Spindle assembly in Xenopus egg extracts: respective roles of centrosomes and microtubule self-organization. J Cell Biol. 138:1997;615-628.
-
(1997)
J Cell Biol
, vol.138
, pp. 615-628
-
-
Heald, R.1
Tournebize, R.2
Habermann, A.3
Karsenti, E.4
Hyman, A.5
-
71
-
-
0030298137
-
A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly
-
Merdes A, Ramyar K, Vechio JD, Cleveland DW A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly. Cell. 87:1996;447-458.
-
(1996)
Cell
, vol.87
, pp. 447-458
-
-
Merdes, A.1
Ramyar, K.2
Vechio, J.D.3
Cleveland, D.W.4
-
72
-
-
0032476724
-
Localization of the kinesin-like protein Xklp2 to spindle poles requires a leucine zipper, a microtubule-associated protein, and dynein
-
This study described how the carboxy-terminal domain of kinesin-like Xklp2 is targeted to spindle poles. The authors show that this localization to the minus ends of microtubules is dependent on a microtubule-associated protein, TPX2, and the dynactin complex.
-
Wittmann T, Boleti H, Antony C, Karsenti E, Vernos I Localization of the kinesin-like protein Xklp2 to spindle poles requires a leucine zipper, a microtubule-associated protein, and dynein. J Cell Biol. 143:1998;673-685. This study described how the carboxy-terminal domain of kinesin-like Xklp2 is targeted to spindle poles. The authors show that this localization to the minus ends of microtubules is dependent on a microtubule-associated protein, TPX2, and the dynactin complex.
-
(1998)
J Cell Biol
, vol.143
, pp. 673-685
-
-
Wittmann, T.1
Boleti, H.2
Antony, C.3
Karsenti, E.4
Vernos, I.5
|