-
1
-
-
0026752620
-
The importance of the T cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis
-
Panayi GS, Lanchbury JS, Kingsley GH. The importance of the T cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis. Arthritis Rheum 1992; 35: 729-35.
-
(1992)
Arthritis Rheum
, vol.35
, pp. 729-735
-
-
Panayi, G.S.1
Lanchbury, J.S.2
Kingsley, G.H.3
-
2
-
-
0032838994
-
T cells: Pathogenic cells and therapeutic targets in rheumatoid arthritis
-
Yocum DE. T cells: pathogenic cells and therapeutic targets in rheumatoid arthritis. Semin Arthritis Rheum 1999; 29: 27-35.
-
(1999)
Semin Arthritis Rheum
, vol.29
, pp. 27-35
-
-
Yocum, D.E.1
-
4
-
-
0034048349
-
Anti-cytokine therapy for rheumatoid arthritis
-
Maini RN, Taylor PC. Anti-cytokine therapy for rheumatoid arthritis. Annu Rev Med 2000; 51: 207-29.
-
(2000)
Annu Rev Med
, vol.51
, pp. 207-229
-
-
Maini, R.N.1
Taylor, P.C.2
-
5
-
-
0023245677
-
FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics
-
Kino T, Hatanaka H, Hashimoto M, Nishiyama M, Goto T, Okuhara M et al. FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics. J Antibiotics 1987; 40: 1249-55.
-
(1987)
J Antibiotics
, vol.40
, pp. 1249-1255
-
-
Kino, T.1
Hatanaka, H.2
Hashimoto, M.3
Nishiyama, M.4
Goto, T.5
Okuhara, M.6
-
6
-
-
0023261356
-
FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro
-
Kino T, Hatanaka H, Miyata S, Inamura N, Nishiyama M, Yajima T et al. FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro. J Antibiotics 1987; 40: 1256-65.
-
(1987)
J Antibiotics
, vol.40
, pp. 1256-1265
-
-
Kino, T.1
Hatanaka, H.2
Miyata, S.3
Inamura, N.4
Nishiyama, M.5
Yajima, T.6
-
7
-
-
0036674871
-
Efficacy of tacrolimus in rheumatoid arthritis patients who have been treated unsuccessfully with methotrexate. A six-month, double-blind, randomized, dose-ranging study
-
Furst DE, Saag K, Fleischmann MR, Sherrer Y, Block JA, Schnitzer T et al. Efficacy of tacrolimus in rheumatoid arthritis patients who have been treated unsuccessfully with methotrexate. A six-month, double-blind, randomized, dose-ranging study. Arthritis Rheum 2002; 46: 2020-8.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 2020-2028
-
-
Furst, D.E.1
Saag, K.2
Fleischmann, M.R.3
Sherrer, Y.4
Block, J.A.5
Schnitzer, T.6
-
8
-
-
10744233211
-
Efficacy and safety of tacrolimus in patients with rheumatoid arthritis
-
Yocum DE, Furst DE, Kaine TL, Baldassare AR, Stevenson JT, Borton MA et al. Efficacy and safety of tacrolimus in patients with rheumatoid arthritis. Arthritis Rheum 2003; 48: 3328-37.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 3328-3337
-
-
Yocum, D.E.1
Furst, D.E.2
Kaine, T.L.3
Baldassare, A.R.4
Stevenson, J.T.5
Borton, M.A.6
-
9
-
-
0742305108
-
Efficacy and safety of tacrolimus (FK506) in treatment of rheumatoid arthritis: A randomized, double blind, placebo controlled dose-finding study
-
Kondo H, Abe T, Hashimoto H, Uchida S, Irimajiri S, Hara M, Sugawara S. Efficacy and safety of tacrolimus (FK506) in treatment of rheumatoid arthritis: A randomized, double blind, placebo controlled dose-finding study. J Rheumatol 2004; 31: 243-51.
-
(2004)
J Rheumatol
, vol.31
, pp. 243-251
-
-
Kondo, H.1
Abe, T.2
Hashimoto, H.3
Uchida, S.4
Irimajiri, S.5
Hara, M.6
Sugawara, S.7
-
10
-
-
0029797189
-
The mechanism of action of cyclosporin A and FK506
-
Ho S, Clipstone N, Timmermann L, Northrop J, Graef I, Fiorentino D et al. The mechanism of action of cyclosporin A and FK506. Clin Immunol Immunopathol 1996; 80: S40-5.
-
(1996)
Clin Immunol Immunopathol
, vol.80
-
-
Ho, S.1
Clipstone, N.2
Timmermann, L.3
Northrop, J.4
Graef, I.5
Fiorentino, D.6
-
11
-
-
0033852795
-
FK506 potently inhibits T cell activation induced TNF-α and IL-1β production in vitro by human peripheral blood mononuclear cells
-
Sakuma S, Kato Y, Nishigaki F, Sasakawa T, Magari K, Miyata S et al. FK506 potently inhibits T cell activation induced TNF-α and IL-1β production in vitro by human peripheral blood mononuclear cells. Br J Pharmacol 2000; 130: 1655-63.
-
(2000)
Br J Pharmacol
, vol.130
, pp. 1655-1663
-
-
Sakuma, S.1
Kato, Y.2
Nishigaki, F.3
Sasakawa, T.4
Magari, K.5
Miyata, S.6
-
12
-
-
0035108541
-
Effects of FK506 and other immunosuppressive anti-rheumatic agents on T cell activation mediated IL-6 and IgM production in vitro
-
Sakuma S, Kato Y, Nishigaki F, Magari K, Miyata S, Ohkubo Y et al. Effects of FK506 and other immunosuppressive anti-rheumatic agents on T cell activation mediated IL-6 and IgM production in vitro. Int Immunopharmacol 2001; 1: 749-57.
-
(2001)
Int Immunopharmacol
, vol.1
, pp. 749-757
-
-
Sakuma, S.1
Kato, Y.2
Nishigaki, F.3
Magari, K.4
Miyata, S.5
Ohkubo, Y.6
-
13
-
-
0141531075
-
Differential effects of FK506 and methotrexate on inflammatory cytokine levels in rat adjuvant-induced arthritis
-
Magari K, Miyata S, Nishigaki F, Ohkubo Y, Mutoh S, Goto T. Differential effects of FK506 and methotrexate on inflammatory cytokine levels in rat adjuvant-induced arthritis. J Rheumatol 2003; 30: 2193-200.
-
(2003)
J Rheumatol
, vol.30
, pp. 2193-2200
-
-
Magari, K.1
Miyata, S.2
Nishigaki, F.3
Ohkubo, Y.4
Mutoh, S.5
Goto, T.6
-
14
-
-
6044261211
-
Inflammatory cytokine levels in paw tissues during development of rat collagen-induced arthritis: Effect of FK506, an inhibitor of T cell activation
-
Magari K, Miyata S, Ohkubo Y, Mutoh S. Inflammatory cytokine levels in paw tissues during development of rat collagen-induced arthritis: Effect of FK506, an inhibitor of T cell activation. Inflamm Res 2004; 53: 469-74.
-
(2004)
Inflamm Res
, vol.53
, pp. 469-474
-
-
Magari, K.1
Miyata, S.2
Ohkubo, Y.3
Mutoh, S.4
-
15
-
-
0347985498
-
Anti-arthritic properties of FK506 on collagen-induced arthritis in rats
-
Magari K, Nishigaki F, Sasakawa T, Ogawa T, Miyata S, Ohkubo Y at al. Anti-arthritic properties of FK506 on collagen-induced arthritis in rats. Inflamm Res 2003; 52: 524-9.
-
(2003)
Inflamm Res
, vol.52
, pp. 524-529
-
-
Magari, K.1
Nishigaki, F.2
Sasakawa, T.3
Ogawa, T.4
Miyata, S.5
Ohkubo, Y.6
-
16
-
-
0034783662
-
FK506 is superior to methotrexate in therapeutic effects on advanced stage of rat adjuvant-induced arthritis
-
Sakuma S, Nishigaki F, Magari K, Ogawa T, Miyata S, Ohkubo Y et al. FK506 is superior to methotrexate in therapeutic effects on advanced stage of rat adjuvant-induced arthritis. Inflamm Res 2001; 50: 509-14.
-
(2001)
Inflamm Res
, vol.50
, pp. 509-514
-
-
Sakuma, S.1
Nishigaki, F.2
Magari, K.3
Ogawa, T.4
Miyata, S.5
Ohkubo, Y.6
-
17
-
-
12144266376
-
Comparison of anti-arthritic properties of leflunomide with methotrexate and FK506: Effect on T cell activation-induced inflammatory cytokine production in vitro and rat adjuvant-induced arthritis
-
Magari K, Miyata S, Nishigaki F, Ohkubo Y, Mutoh S. Comparison of anti-arthritic properties of leflunomide with methotrexate and FK506: Effect on T cell activation-induced inflammatory cytokine production in vitro and rat adjuvant-induced arthritis. Inflamm Res 2004; 53: 544-50.
-
(2004)
Inflamm Res
, vol.53
, pp. 544-550
-
-
Magari, K.1
Miyata, S.2
Nishigaki, F.3
Ohkubo, Y.4
Mutoh, S.5
-
18
-
-
0038637479
-
Calcineurin inhibitors exert rapid reduction of inflammatory pain in rat adjuvant-induced arthritis
-
Magari K, Miyata S, Ohkubo Y, Mutoh S, Goto T. Calcineurin inhibitors exert rapid reduction of inflammatory pain in rat adjuvant-induced arthritis. Br J Pharmacol 2003; 139: 927-34.
-
(2003)
Br J Pharmacol
, vol.139
, pp. 927-934
-
-
Magari, K.1
Miyata, S.2
Ohkubo, Y.3
Mutoh, S.4
Goto, T.5
-
19
-
-
0037154572
-
FK506 induces chondrogenic differentiation of a clonal mouse embryonic cell line. ATDC5
-
Nishigaki F, Sakuma S, Ogawa T, Miyata S, Ohkubo Y, Goto T. FK506 induces chondrogenic differentiation of a clonal mouse embryonic cell line. ATDC5. Eur J Pharmacol 2002; 437: 123-8.
-
(2002)
Eur J Pharmacol
, vol.437
, pp. 123-128
-
-
Nishigaki, F.1
Sakuma, S.2
Ogawa, T.3
Miyata, S.4
Ohkubo, Y.5
Goto, T.6
-
20
-
-
0028586815
-
+ T cell contact-dependent activation of monocyte interleukin-1 synthesis
-
+ T cell contact-dependent activation of monocyte interleukin-1 synthesis. Eur J Immunol 1994; 24: 3148-54.
-
(1994)
Eur J Immunol
, vol.24
, pp. 3148-3154
-
-
Wagner Jr., D.W.1
Stout, R.D.2
Suttles, J.3
-
21
-
-
0033605124
-
CD40 signaling of monocyte inflammatory cytokine synthesis through an ERK1/2-dependent pathway
-
Suttles J, Milhorn DM, Miller RW, Poe JC, Wahl LM, Stout RD. CD40 signaling of monocyte inflammatory cytokine synthesis through an ERK1/2-dependent pathway. J Biol Chem 1999; 274: 5835-42.
-
(1999)
J Biol Chem
, vol.274
, pp. 5835-5842
-
-
Suttles, J.1
Milhorn, D.M.2
Miller, R.W.3
Poe, J.C.4
Wahl, L.M.5
Stout, R.D.6
-
22
-
-
0029950655
-
CD2 regulates T cell-dependent induction of monocyte IL-1β mRNA during anti-CD3 mitogenesis
-
McAllister PT, Ellis TM. CD2 regulates T cell-dependent induction of monocyte IL-1β mRNA during anti-CD3 mitogenesis. Cell Iminunol 1996; 170: 120-6.
-
(1996)
Cell Iminunol
, vol.170
, pp. 120-126
-
-
McAllister, P.T.1
Ellis, T.M.2
-
23
-
-
0031050988
-
Cytokine stimulation of T lymphocytes regulates their capacity to induce monocyte production of tumor necrosis factor-α, but not interleukin-10: Possible relevance to pathophysiology of rheumatoid arthritis
-
1997
-
Sebbag M, Parry SL, Brennan FM, Feldmann M. 1997. Cytokine stimulation of T lymphocytes regulates their capacity to induce monocyte production of tumor necrosis factor-α, but not interleukin-10: possible relevance to pathophysiology of rheumatoid arthritis. Eur J Immunol 1997; 27: 624-32.
-
(1997)
Eur J Immunol
, vol.27
, pp. 624-632
-
-
Sebbag, M.1
Parry, S.L.2
Brennan, F.M.3
Feldmann, M.4
-
24
-
-
0034457826
-
Cell contact-mediated signaling of monocytes by stimulated T cells: A major pathway for cytokine induction
-
Burger D. Cell contact-mediated signaling of monocytes by stimulated T cells: a major pathway for cytokine induction. Eur Cytokine Netw 2000; 11: 346-53.
-
(2000)
Eur Cytokine Netw
, vol.11
, pp. 346-353
-
-
Burger, D.1
-
25
-
-
0024412228
-
The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes
-
Tocci MJ, Matkovich DA, Collier KA, Kwok P, Dumont F, Lin S et al. The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes. J Immunol 1989; 143: 718-26.
-
(1989)
J Immunol
, vol.143
, pp. 718-726
-
-
Tocci, M.J.1
Matkovich, D.A.2
Collier, K.A.3
Kwok, P.4
Dumont, F.5
Lin, S.6
-
26
-
-
0036241265
-
Newer immunosuppressive drugs. Their potential role in rheumatoid arthritis therapy
-
Drosos AA. Newer immunosuppressive drugs. Their potential role in rheumatoid arthritis therapy. Drugs 2002; 62: 891-907.
-
(2002)
Drugs
, vol.62
, pp. 891-907
-
-
Drosos, A.A.1
-
27
-
-
0029589336
-
Auranofin inhibits the induction of interleukin 1β and tumor necrosis factor α mRNA in macrophages
-
Bondeson J, Sundler R. Auranofin inhibits the induction of interleukin 1β and tumor necrosis factor α mRNA in macrophages. Biochem Pharmacol 1995; 50: 1753-9.
-
(1995)
Biochem Pharmacol
, vol.50
, pp. 1753-1759
-
-
Bondeson, J.1
Sundler, R.2
-
28
-
-
0029129429
-
The effects of antiinflammatory and antiallergic drugs on cytokine release after stimulation of human whole blood by lipopolysaccharide and zymosan A
-
Hartman DA, Ochalski SJ, Carlson RP. The effects of antiinflammatory and antiallergic drugs on cytokine release after stimulation of human whole blood by lipopolysaccharide and zymosan A. Inflamm Res 1995; 44: 269-74.
-
(1995)
Inflamm Res
, vol.44
, pp. 269-274
-
-
Hartman, D.A.1
Ochalski, S.J.2
Carlson, R.P.3
-
29
-
-
0036899088
-
An in vitro screening assay for the detection of inhibitors of proinflammatory cytokine synthesis: A useful tool for the development of new antiarthritic and disease modifying drugs
-
Laufer S, Greim C, Bertsche T. An in vitro screening assay for the detection of inhibitors of proinflammatory cytokine synthesis: a useful tool for the development of new antiarthritic and disease modifying drugs. Osteoarthr Cartilage 2002; 10: 961-7.
-
(2002)
Osteoarthr Cartilage
, vol.10
, pp. 961-967
-
-
Laufer, S.1
Greim, C.2
Bertsche, T.3
-
30
-
-
0036234632
-
An anti-rheumatic agent T-614 inhibits NF-κB activation in LPS- And TNF-α-stimulated THP-1 cells without interfering with IκBα degradation
-
Aikawa Y, Yamamoto M, Yamamoto T, Morimoto K, Tanaka K. An anti-rheumatic agent T-614 inhibits NF-κB activation in LPS- and TNF-α-stimulated THP-1 cells without interfering with IκBα degradation. Inflamm Res 2002; 51: 188-94.
-
(2002)
Inflamm Res
, vol.51
, pp. 188-194
-
-
Aikawa, Y.1
Yamamoto, M.2
Yamamoto, T.3
Morimoto, K.4
Tanaka, K.5
-
31
-
-
0035104119
-
LPS induction of gene expression in human monocytes
-
Guha M, Mackman N. LPS induction of gene expression in human monocytes. Cell Signal 2001; 13: 85-94.
-
(2001)
Cell Signal
, vol.13
, pp. 85-94
-
-
Guha, M.1
Mackman, N.2
-
32
-
-
0030426902
-
Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function
-
Badger AM, Bradbeer JN, Votta B, Lee JC, Adams JL, Griswold DE. Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function. J Pharmacol Exp Ther 1996; 279: 1453-61.
-
(1996)
J Pharmacol Exp Ther
, vol.279
, pp. 1453-1461
-
-
Badger, A.M.1
Bradbeer, J.N.2
Votta, B.3
Lee, J.C.4
Adams, J.L.5
Griswold, D.E.6
-
33
-
-
0142026209
-
p38 map kinases: Key signaling molecules as therapeutic targets for inflammatory diseases
-
Kumar S, Boehm J, Lee JC. p38 map kinases: Key signaling molecules as therapeutic targets for inflammatory diseases. Nat Rev Drug Discov 2003; 2: 717-26.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 717-726
-
-
Kumar, S.1
Boehm, J.2
Lee, J.C.3
-
34
-
-
0242410494
-
Infections and anti-tumor necrosis factor α therapy
-
Ellerin T, Rubin RH, Weinblatt ME. Infections and anti-tumor necrosis factor α therapy. Arthritis Rheum 2003; 48: 3013-22.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 3013-3022
-
-
Ellerin, T.1
Rubin, R.H.2
Weinblatt, M.E.3
-
35
-
-
0037955831
-
Anti-cytokine therapeutics and infections
-
Dinarello CA. Anti-cytokine therapeutics and infections. Vaccine 2003; 21: S2/24-S2/34.
-
(2003)
Vaccine
, vol.21
-
-
Dinarello, C.A.1
-
36
-
-
0031658404
-
Commonly used disease-modifying antirheumatic drags in the treatment of inflammatory arthritis: An update on mechanism of action
-
Danning CL, Boumpas DT. Commonly used disease-modifying antirheumatic drags in the treatment of inflammatory arthritis: An update on mechanism of action. Clin Exp Rheumatol 1998; 16: 595-604.
-
(1998)
Clin Exp Rheumatol
, vol.16
, pp. 595-604
-
-
Danning, C.L.1
Boumpas, D.T.2
-
37
-
-
0030023020
-
Pancytopenia secondary to methotrexate therapy in rheumatoid arthritis
-
Gutierrez-Ureña S, Molina JF, García CO, Cuéllar ML, Espinoza LR. Pancytopenia secondary to methotrexate therapy in rheumatoid arthritis. Arthritis Rheum 1996; 39: 272-6.
-
(1996)
Arthritis Rheum
, vol.39
, pp. 272-276
-
-
Gutierrez-Ureña, S.1
Molina, J.F.2
García, C.O.3
Cuéllar, M.L.4
Espinoza, L.R.5
-
38
-
-
0033764113
-
Leflunomide: Mode of action in the treatment of rheumatoid arthritis
-
Breedveld FC, Dayer J-M. Leflunomide: mode of action in the treatment of rheumatoid arthritis. Ann Rheum Dis 2000; 59: 841-9.
-
(2000)
Ann Rheum Dis
, vol.59
, pp. 841-849
-
-
Breedveld, F.C.1
Dayer, J.-M.2
-
39
-
-
0033803718
-
Neurotoxicity of calcineurin inhibitors: Impact and clinical management
-
Bechstein WO. Neurotoxicity of calcineurin inhibitors: impact and clinical management. Transplant Int 2000; 13: 313-26.
-
(2000)
Transplant Int
, vol.13
, pp. 313-326
-
-
Bechstein, W.O.1
-
40
-
-
0031012546
-
Nephrotoxicity of immunosuppressive drugs: Experimental and clinical observations
-
Andoh TF, Burdmann EA, Bennett WM. Nephrotoxicity of immunosuppressive drugs: experimental and clinical observations. Semin Nephrol 1997; 17: 34-45.
-
(1997)
Semin Nephrol
, vol.17
, pp. 34-45
-
-
Andoh, T.F.1
Burdmann, E.A.2
Bennett, W.M.3
-
41
-
-
0020955842
-
Models of arthritis and the search for antiarthritic drugs
-
Billingham MEJ. Models of arthritis and the search for antiarthritic drugs. Pharmac Ther 1983; 21: 389-428.
-
(1983)
Pharmac Ther
, vol.21
, pp. 389-428
-
-
Billingham, M.E.J.1
-
43
-
-
0033067522
-
Antiarthritic activity of soluble tumor necrosis factor receptor type I forms in adjuvant arthritis: Correlation of plasma levels with efficacy
-
McComb J, Gould T, Chlipala E, Sennello G, Frazier J, Kieft G et al. Antiarthritic activity of soluble tumor necrosis factor receptor type I forms in adjuvant arthritis: Correlation of plasma levels with efficacy. J Rheumatol 1999; 26: 1347-51.
-
(1999)
J Rheumatol
, vol.26
, pp. 1347-1351
-
-
McComb, J.1
Gould, T.2
Chlipala, E.3
Sennello, G.4
Frazier, J.5
Kieft, G.6
-
44
-
-
0026644298
-
Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis
-
Williams RO, Feldmann M, Maini RN. Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc Natl Acad Sci USA 1992; 89: 9784-8.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 9784-9788
-
-
Williams, R.O.1
Feldmann, M.2
Maini, R.N.3
-
45
-
-
0033016267
-
Efficacy of sustained blood levels of interleukin-1 receptor antagonist in animal models of arthritis. Comparison of efficacy in animal models with human clinical data
-
Bendele A, McAbee T, Sennello G, Frazier J, Chlipala E, McCabe D. Efficacy of sustained blood levels of interleukin-1 receptor antagonist in animal models of arthritis. Comparison of efficacy in animal models with human clinical data. Arthritis Rheum 1999; 42: 498-506.
-
(1999)
Arthritis Rheum
, vol.42
, pp. 498-506
-
-
Bendele, A.1
McAbee, T.2
Sennello, G.3
Frazier, J.4
Chlipala, E.5
McCabe, D.6
-
46
-
-
0032429668
-
Blockage of interleukin-6 receptor ameliorates joint disease in murine collagen-induced arthritis
-
Takagi N, Mihara M, Moriya Y, Nishimoto N, Yoshizaki K, Kishimoto T et al. Blockage of interleukin-6 receptor ameliorates joint disease in murine collagen-induced arthritis. Arthritis Rheum 1998; 41: 2117-21.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 2117-2121
-
-
Takagi, N.1
Mihara, M.2
Moriya, Y.3
Nishimoto, N.4
Yoshizaki, K.5
Kishimoto, T.6
-
47
-
-
0034967902
-
Severe inflammatory arthritis and lymphadenopathy in the absence of TNF
-
Campbell IK, O'Donnell K, Lawlor KE, Wicks IP. Severe inflammatory arthritis and lymphadenopathy in the absence of TNF. J Clin Invest 2001; 107: 1519-27.
-
(2001)
J Clin Invest
, vol.107
, pp. 1519-1527
-
-
Campbell, I.K.1
O'Donnell, K.2
Lawlor, K.E.3
Wicks, I.P.4
-
48
-
-
0141788311
-
Prevention of the onset and progression of collagen-induced arthritis in rats by the potent p38 mitogen-activated protein kinase inhibitor FR167653
-
Nishikawa N, Myoui A, Tomita T, Takahi K, Nampei A, Yoshikawa H. Prevention of the onset and progression of collagen-induced arthritis in rats by the potent p38 mitogen-activated protein kinase inhibitor FR167653. Arthritis Rheum 2003; 48: 2670-81.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 2670-2681
-
-
Nishikawa, N.1
Myoui, A.2
Tomita, T.3
Takahi, K.4
Nampei, A.5
Yoshikawa, H.6
-
49
-
-
0035056003
-
Anti-TNF α therapy of rheumatoid arthritis: What have we learned?
-
Feldmann M, Maini RN. Anti-TNF α therapy of rheumatoid arthritis: What have we learned? Annu Rev Immunol 2001; 19: 163-96.
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 163-196
-
-
Feldmann, M.1
Maini, R.N.2
-
50
-
-
0034125853
-
Temporal expression of inflammatory cytokines and chemokines in rat adjuvant-induced arthritis
-
Szekanecz Z, Halloran MM, Volin MV, Woods JM, Strieter RM, Haines III GK et al. Temporal expression of inflammatory cytokines and chemokines in rat adjuvant-induced arthritis. Arthritis Rheum 2000; 43: 1266-77.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 1266-1277
-
-
Szekanecz, Z.1
Halloran, M.M.2
Volin, M.V.3
Woods, J.M.4
Strieter, R.M.5
Haines III, G.K.6
-
51
-
-
0027507790
-
Elevated levels of TNF in the joints of adjuvant arthritic rats
-
Smith-Oliver T, Noel LS, Stimpson SS, Yarnall DP, Connolly KM. Elevated levels of TNF in the joints of adjuvant arthritic rats. Cytokine 1993;5;298-304.
-
(1993)
Cytokine
, vol.5
, pp. 298-304
-
-
Smith-Oliver, T.1
Noel, L.S.2
Stimpson, S.S.3
Yarnall, D.P.4
Connolly, K.M.5
-
52
-
-
0000952204
-
Arthritis induced by a T-lymphocyte clone that responds to Mycobacterium tuberculosis and to cartilage proteoglycans
-
Van Eden W, Holoshitz J, Nevo Z, Frenkel A, Klajman A, Cohen IR. Arthritis induced by a T-lymphocyte clone that responds to Mycobacterium tuberculosis and to cartilage proteoglycans. Proc Natl Acad Sci USA 1985; 82: 5117-20.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 5117-5120
-
-
Van Eden, W.1
Holoshitz, J.2
Nevo, Z.3
Frenkel, A.4
Klajman, A.5
Cohen, I.R.6
-
54
-
-
0023884046
-
Immunosuppressive effect of FK506 on collagen-induced arthritis in rats
-
Inamura N, Hashimoto M, Nakahara K, Aoki H, Yamaguchi I, Kohsaka M. Immunosuppressive effect of FK506 on collagen-induced arthritis in rats. Clin Immunol Immunopathol 1988; 46: 82-90.
-
(1988)
Clin Immunol Immunopathol
, vol.46
, pp. 82-90
-
-
Inamura, N.1
Hashimoto, M.2
Nakahara, K.3
Aoki, H.4
Yamaguchi, I.5
Kohsaka, M.6
-
55
-
-
0034079892
-
Functional disability and quality-of-life assessment in clinical practice
-
Guillemin F. Functional disability and quality-of-life assessment in clinical practice. Rheumatology 2000; 39(suppl. 1): 17-23.
-
(2000)
Rheumatology
, vol.39
, Issue.1 SUPPL.
, pp. 17-23
-
-
Guillemin, F.1
-
56
-
-
0033495154
-
Function and health-related quality of life. Results from randomized controlled trial of leflunomide versus methotrexate or placebo in patients with active rheumatoid arthritis
-
Strand V, Tugwell P, Bombardier C, Maetzel A, Crawford B, Dorrier C et al. Function and health-related quality of life. Results from randomized controlled trial of leflunomide versus methotrexate or placebo in patients with active rheumatoid arthritis. Arthritis Rheum 1999; 42: 1870-8.
-
(1999)
Arthritis Rheum
, vol.42
, pp. 1870-1878
-
-
Strand, V.1
Tugwell, P.2
Bombardier, C.3
Maetzel, A.4
Crawford, B.5
Dorrier, C.6
-
57
-
-
0034039972
-
Clinical improvement as reflected in measures of function and health-related quality of life following treatment with leflunomide compared with methotrexate in patients with rheumatoid arthritis. Sensitivity and relative efficiency to detect a treatment in a twelve-month, placebo-controlled trial
-
Tugwell P, Wells G, Strand V, Maetzel A, Bombardier C, Crawford B et al. Clinical improvement as reflected in measures of function and health-related quality of life following treatment with leflunomide compared with methotrexate in patients with rheumatoid arthritis. Sensitivity and relative efficiency to detect a treatment in a twelve-month, placebo-controlled trial. Arthritis Rheum 2000; 43: 506-14.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 506-514
-
-
Tugwell, P.1
Wells, G.2
Strand, V.3
Maetzel, A.4
Bombardier, C.5
Crawford, B.6
-
58
-
-
0034877904
-
Improved functional ability in patients with rheumatoid arthritis - Longterm treatment with leflunomide versus sulfasalazine
-
Kalden JR, Scott DL, Smolen JS, Schattenkirchner M, Rozman B, Williams BD et al. Improved functional ability in patients with rheumatoid arthritis - Longterm treatment with leflunomide versus sulfasalazine. J Rheumatol 2001; 28: 1983-91.
-
(2001)
J Rheumatol
, vol.28
, pp. 1983-1991
-
-
Kalden, J.R.1
Scott, D.L.2
Smolen, J.S.3
Schattenkirchner, M.4
Rozman, B.5
Williams, B.D.6
-
59
-
-
0036050213
-
The effects of disease-modifying anti-rheumatic drugs on health assessment questionnaire score. Lessons from the leflunomide clinical trials database
-
Scott DL, Strand V. The effects of disease-modifying anti-rheumatic drugs on health assessment questionnaire score. Lessons from the leflunomide clinical trials database. Rheumatology 2002; 41: 899-909.
-
(2002)
Rheumatology
, vol.41
, pp. 899-909
-
-
Scott, D.L.1
Strand, V.2
-
60
-
-
18044400396
-
Two-year, blinded, randomized, controlled trial of treatment of active rheumatoid arthritis with leflunomide compared with methotrexate
-
Cohen S, Cannon GW, Schiff M, Weaver A, Fox R, Olsen N et al. Two-year, blinded, randomized, controlled trial of treatment of active rheumatoid arthritis with leflunomide compared with methotrexate. Arthritis Rheum 2001; 44: 1984-92.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 1984-1992
-
-
Cohen, S.1
Cannon, G.W.2
Schiff, M.3
Weaver, A.4
Fox, R.5
Olsen, N.6
-
61
-
-
0023125509
-
Functional assessment of the hand: Reproducibility, acceptability, and utility of a new system for measuring strength
-
Helliwell P, Howe A, Wright V Functional assessment of the hand: reproducibility, acceptability, and utility of a new system for measuring strength. Ann Rheum Dis 1987; 46: 203-8.
-
(1987)
Ann Rheum Dis
, vol.46
, pp. 203-208
-
-
Helliwell, P.1
Howe, A.2
Wright, V.3
-
62
-
-
0029888972
-
Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis
-
Anderson GD, Hauser SD, McGarity KL, Bremer ME, Isakson PC, Gregory SA. Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis. J Clin Invest 1996; 97: 2672-9.
-
(1996)
J Clin Invest
, vol.97
, pp. 2672-2679
-
-
Anderson, G.D.1
Hauser, S.D.2
McGarity, K.L.3
Bremer, M.E.4
Isakson, P.C.5
Gregory, S.A.6
-
63
-
-
0029787626
-
2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo
-
2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo. J Exp Med 1996; 184: 883-91.
-
(1996)
J Exp Med
, vol.184
, pp. 883-891
-
-
Portanova, J.P.1
Zhang, Y.2
Anderson, G.D.3
Hauser, S.D.4
Masferrer, J.L.5
Seibert, K.6
-
64
-
-
0033031331
-
COX-2 inhibitors
-
Hawkey CJ. COX-2 inhibitors. Lancet 1999; 353: 307-14.
-
(1999)
Lancet
, vol.353
, pp. 307-314
-
-
Hawkey, C.J.1
-
65
-
-
0023679882
-
Interleukin-1β as a potent hyperalgesic agent antagonized by a tripeptide analogue
-
Ferreira SH, Lorenzetti BB, Bristow AF, Poole S. Interleukin-1β as a potent hyperalgesic agent antagonized by a tripeptide analogue. Nature 1988; 334: 698-700.
-
(1988)
Nature
, vol.334
, pp. 698-700
-
-
Ferreira, S.H.1
Lorenzetti, B.B.2
Bristow, A.F.3
Poole, S.4
-
66
-
-
0026787367
-
The pivotal role of tumour necrosis factor α in the development of inflammatory hyperalgesia
-
Cunha FQ, Poole S, Lorenzetti BB, Ferreira SH. The pivotal role of tumour necrosis factor α in the development of inflammatory hyperalgesia. Br J Pharmacol 1992; 107: 660-4.
-
(1992)
Br J Pharmacol
, vol.107
, pp. 660-664
-
-
Cunha, F.Q.1
Poole, S.2
Lorenzetti, B.B.3
Ferreira, S.H.4
-
67
-
-
0028982492
-
Contribution of interleukin-1β to the inflammation-induced increase in nerve growth factor levels and inflammatory hyperalgesia
-
Safieh-Garabedian B, Poole S, Allchorne A, Winter J, Woolf CJ. Contribution of interleukin-1β to the inflammation-induced increase in nerve growth factor levels and inflammatory hyperalgesia. Br J Pharmacol 1995; 115: 1265-75.
-
(1995)
Br J Pharmacol
, vol.115
, pp. 1265-1275
-
-
Safieh-Garabedian, B.1
Poole, S.2
Allchorne, A.3
Winter, J.4
Woolf, C.J.5
-
68
-
-
0030913028
-
Cytokines, nerve growth factor and inflammatory hyperalgesia: The contribution of tumour necrosis factor α
-
Woolf CJ, Allchorne A, Safieh-Garabedian B, Poole S. Cytokines, nerve growth factor and inflammatory hyperalgesia: the contribution of tumour necrosis factor α. Br J Pharmacol 1997; 121: 417-24.
-
(1997)
Br J Pharmacol
, vol.121
, pp. 417-424
-
-
Woolf, C.J.1
Allchorne, A.2
Safieh-Garabedian, B.3
Poole, S.4
-
69
-
-
0037654460
-
Interleukin-1 and tumor necrosis factor: Rheumatoid arthritis and pain
-
L.R. Watkins, and S.F. Maier, eds. Birkäuser, Basel, Switzerland
-
Martin D. Interleukin-1 and tumor necrosis factor: Rheumatoid arthritis and pain. In: Cytokines and Pain. L.R. Watkins, and S.F. Maier, eds. Birkäuser, Basel, Switzerland, 1999; 205-19.
-
(1999)
Cytokines and Pain
, pp. 205-219
-
-
Martin, D.1
-
70
-
-
0031309575
-
FK506 and the role of immunophilins in nerve regeneration
-
Gold BG. FK506 and the role of immunophilins in nerve regeneration. Mol Neurobiol 1997; 15: 285-306.
-
(1997)
Mol Neurobiol
, vol.15
, pp. 285-306
-
-
Gold, B.G.1
-
71
-
-
0141818987
-
Immunophilins in nervous system degeneration and regeneration
-
Avramut M, Achim CL. Immunophilins in nervous system degeneration and regeneration. Curr Top Med Chem 2003; 3: 1376-82.
-
(2003)
Curr Top Med Chem
, vol.3
, pp. 1376-1382
-
-
Avramut, M.1
Achim, C.L.2
-
72
-
-
0036180694
-
FK506 enhanced oeseoblastic differentiation in mesenchymal cells
-
Tang L, Ebara S, Kawasaki S, Wakabayashi S, Nikaido T, Takaoka K. FK506 enhanced oeseoblastic differentiation in mesenchymal cells. Cell Biol Int 2002; 26: 75-84.
-
(2002)
Cell Biol Int
, vol.26
, pp. 75-84
-
-
Tang, L.1
Ebara, S.2
Kawasaki, S.3
Wakabayashi, S.4
Nikaido, T.5
Takaoka, K.6
-
73
-
-
0033844197
-
Immunosuppression with FK506 increases bone induction in demineralized isogenic and xenogenic bone matrix in the rat
-
Voggenreiter G, Assenmacher S, Kreuzfelder E, Wolf M, Kim M-R, Nast-Kolb D et al. Immunosuppression with FK506 increases bone induction in demineralized isogenic and xenogenic bone matrix in the rat. J Bone Miner Res 2000; 15: 1825-34.
-
(2000)
J Bone Miner Res
, vol.15
, pp. 1825-1834
-
-
Voggenreiter, G.1
Assenmacher, S.2
Kreuzfelder, E.3
Wolf, M.4
Kim, M.-R.5
Nast-Kolb, D.6
-
74
-
-
0033595129
-
TAK-778, a novel synthetic 3-benzothiepin derivative, promotes chondrogenesis in vitro and in vivo
-
Akiyama H, Fukumoto A, Shigeno C, Ito H, Mukai S, Hoshino T et al. TAK-778, a novel synthetic 3-benzothiepin derivative, promotes chondrogenesis in vitro and in vivo. Biochem Biophys Res Commun 1999; 261: 131-8.
-
(1999)
Biochem Biophys Res Commun
, vol.261
, pp. 131-138
-
-
Akiyama, H.1
Fukumoto, A.2
Shigeno, C.3
Ito, H.4
Mukai, S.5
Hoshino, T.6
-
75
-
-
0035072358
-
Stem cells for repair of cartilage and bone: The next challenge in osteoarthritis and rheumatoid arthritis
-
Jorgensen C, Noel D, Apparailly F, Sany J. Stem cells for repair of cartilage and bone: the next challenge in osteoarthritis and rheumatoid arthritis. Ann Rheum Dis 2001; 60: 305-9.
-
(2001)
Ann Rheum Dis
, vol.60
, pp. 305-309
-
-
Jorgensen, C.1
Noel, D.2
Apparailly, F.3
Sany, J.4
-
76
-
-
0036667101
-
Regenerative medicine through mesenchymal stem cells for bone and cartilage repair
-
Noël D, Djouad F, Jorgensen C. Regenerative medicine through mesenchymal stem cells for bone and cartilage repair. Curr Opin Investig Drugs 2002; 3: 1000-4.
-
(2002)
Curr Opin Investig Drugs
, vol.3
, pp. 1000-1004
-
-
Noël, D.1
Djouad, F.2
Jorgensen, C.3
-
77
-
-
0033763544
-
Adenovirus-mediated gene transfer of insulin-like growth factor 1 stimulates proteoglycan synthesis in rabbit joints
-
Mi Z, Ghivizzani SC, Lechman ER, Jaffurs D, Glorioso JC, Evans CH, Robbins PD. Adenovirus-mediated gene transfer of insulin-like growth factor 1 stimulates proteoglycan synthesis in rabbit joints. Arthritis Rheum 2000; 43: 2563-70.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 2563-2570
-
-
Mi, Z.1
Ghivizzani, S.C.2
Lechman, E.R.3
Jaffurs, D.4
Glorioso, J.C.5
Evans, C.H.6
Robbins, P.D.7
-
78
-
-
0031941319
-
Stimulation of articular cartilage repair in established arthritis by local administration of transforming growth factor-β into murine knee joints
-
Glansbeek HL, van Beuningen HM, Vitters EL, van der Kraan PM, van den Berg WB. Stimulation of articular cartilage repair in established arthritis by local administration of transforming growth factor-β into murine knee joints. Lab Invest 1998; 78: 133-42.
-
(1998)
Lab Invest
, vol.78
, pp. 133-142
-
-
Glansbeek, H.L.1
Van Beuningen, H.M.2
Vitters, E.L.3
Van Der Kraan, P.M.4
Van Den Berg, W.B.5
-
79
-
-
0034544946
-
Combination benefit of treatment with the cytokine inhibitors interleukin-1 receptor antagonist and PEGylated soluble tumor necrosis factor receptor type I in animal models of rheumatoid arthritis
-
Bendele AM, Chlipala ES, Scherrer J, Frazier J, Sennello G, Rich WJ et al. Combination benefit of treatment with the cytokine inhibitors interleukin-1 receptor antagonist and PEGylated soluble tumor necrosis factor receptor type I in animal models of rheumatoid arthritis. Arthritis Rheum 2000; 43: 2648-59.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 2648-2659
-
-
Bendele, A.M.1
Chlipala, E.S.2
Scherrer, J.3
Frazier, J.4
Sennello, G.5
Rich, W.J.6
-
80
-
-
4344656186
-
Safety of tacrolimus in patients with rheumatoid arthritis: Long-term experience
-
Yocum DE, Furst DE, Bensen WG, Burch FX, Borton MA, Mengle-Gaw LJ et al. Safety of tacrolimus in patients with rheumatoid arthritis: long-term experience. Rheumatology 2004; 43: 992-9.
-
(2004)
Rheumatology
, vol.43
, pp. 992-999
-
-
Yocum, D.E.1
Furst, D.E.2
Bensen, W.G.3
Burch, F.X.4
Borton, M.A.5
Mengle-Gaw, L.J.6
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