Clinical improvement as reflected in measures of function and health- related quality of life following treatment with leflunomide compared with methotrexate in patients with rheumatoid arthritis: Sensitivity and relative efficiency to detect a treatment effect in a twelve-month, placebo-controlled trial

Arthritis and Rheumatism

Volumn 43, Issue 3, 2000, Pages 506-514

  Tugwell, Peter ^a   Wells, George ^a   Strand, Vibeke ^b   Maetzel, Andreas ^a   Bombardier, Claire ^a   Crawford, Bruce ^c   Dorrier, Catherine ^c   Thompson, Ann ^c   Tindall, Elizabeth ^d   Offenberg, Howard ^d   Poiley, Jeffrey ^d   Rutstein, Joel ^d   Dietz, Frederick ^d   Brodsky, Alan ^d   Harris, Robert ^d   Lowenstein, Mitchel ^d   Baldessare, Andrew ^d   Howard, Paul ^d   Sack, Marshall ^d   Tesser, John ^d   Wei, Nathan ^d   Dore, Robin ^d   Ettlinger, Robert ^d   Anderson, Larry ^d   Bockow, Barry ^d   Liebling, Michael ^d   Romain, Paul ^d   Baumgartner, Scott ^d   Silverfield, Joel ^d   Chubick, Andrew ^d   Franklin, Charles ^d   Grove, Willow ^d   Cohen, Selwyn ^d   Senter, Gordon ^d   Furie, Richard ^d   Hartman, Sanford ^d   Levy, Robert ^d   Yocum, David ^d   Cheatum, Don ^d   Lee, Sicy ^d   Heller, Matthew ^d   more..

^a UNIVERSITY OF OTTAWA   (Canada)

^b STANFORD UNIVERSITY   (United States)

^c SANOFI   (France)

^d General Campus ^*

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; LEFLUNOMIDE; METHOTREXATE;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISABILITY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PAIN ASSESSMENT; PHYSICAL ACTIVITY; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; RHEUMATOID ARTHRITIS; SCORING SYSTEM; TREATMENT OUTCOME;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; DOUBLE-BLIND METHOD; HUMANS; ISOXAZOLES; JOINTS; METHOTREXATE; QUALITY OF LIFE; TREATMENT OUTCOME;

EID: 0034039972     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(200003)43:3<506::AID-ANR5>3.0.CO;2-U     Document Type: Article

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