-
2
-
-
0026752620
-
The importance of the T cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis
-
Panayi GS, Lanchbury JS, Kingsley GH. The importance of the T cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis. Arthritis Rheum 1992; 35: 729-35.
-
(1992)
Arthritis Rheum
, vol.35
, pp. 729-735
-
-
Panayi, G.S.1
Lanchbury, J.S.2
Kingsley, G.H.3
-
3
-
-
0034048349
-
Anti-cytokine therapy for rheumatoid arthritis
-
Maini RN, Taylor PC. Anti-cytokine therapy for rheumatoid arthritis. Annu Rev Med 2000; 51: 207-29.
-
(2000)
Annu Rev Med
, vol.51
, pp. 207-229
-
-
Maini, R.N.1
Taylor, P.C.2
-
4
-
-
0035056003
-
Anti-TNFα therapy of rheumatoid arthritis: What have we learned?
-
Feldmann M, Maini RN. Anti-TNFα therapy of rheumatoid arthritis: What have we learned? Annu Rev Immunol 2001; 19: 163-96.
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 163-196
-
-
Feldmann, M.1
Maini, R.N.2
-
5
-
-
0017657009
-
Autoimmunity to type II collagen: An experimental model of arthritis
-
Trentham DE, Townes AS, Kang AH. Autoimmunity to type II collagen: an experimental model of arthritis. J Exp Med 1977; 146: 857-68.
-
(1977)
J Exp Med
, vol.146
, pp. 857-868
-
-
Trentham, D.E.1
Townes, A.S.2
Kang, A.H.3
-
8
-
-
0026644298
-
Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis
-
Williams RO, Feldmann M, Maini RN. Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc Natl Acad Sci USA 1992; 89: 9784-8.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 9784-9788
-
-
Williams, R.O.1
Feldmann, M.2
Maini, R.N.3
-
9
-
-
0034544946
-
Combination benefit of treatment with the cytokine inhibitors interleukin-1 receptor antagonist and PEGylated soluble tumor necrosis factor receptor type I in animal models of rheumatoid arthritis
-
Bendele AM, Chlipala ES, Scherrer J, Frazier J, Sennello G, Rich WJ et al. Combination benefit of treatment with the cytokine inhibitors interleukin-1 receptor antagonist and PEGylated soluble tumor necrosis factor receptor type I in animal models of rheumatoid arthritis. Arthritis Rheum 2000; 43: 2648-59.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 2648-2659
-
-
Bendele, A.M.1
Chlipala, E.S.2
Scherrer, J.3
Frazier, J.4
Sennello, G.5
Rich, W.J.6
-
11
-
-
0033016267
-
Effiicacy of sustained blood levels of interleukin-1 receptor antagonist in animal models of arthritis. Comparison of efficacy in animal models with human clinical data
-
Bendele A, McAbee T, Sennello G, Frazier J, Chlipala E, McCabe D. Effiicacy of sustained blood levels of interleukin-1 receptor antagonist in animal models of arthritis. Comparison of efficacy in animal models with human clinical data. Arthritis Rheum 1999; 42: 498-506.
-
(1999)
Arthritis Rheum
, vol.42
, pp. 498-506
-
-
Bendele, A.1
McAbee, T.2
Sennello, G.3
Frazier, J.4
Chlipala, E.5
McCabe, D.6
-
12
-
-
0032429668
-
Blockage of interleukin-6 receptor ameliorates joint disease in murine collagen-induced arthritis
-
Takagi N, Mihara M, Moriya Y, Nishimoto N, Yoshizaki K, Kishimoto T, et al. Blockage of interleukin-6 receptor ameliorates joint disease in murine collagen-induced arthritis. Arthritis Rheum 1998; 41; 2117-21.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 2117-2121
-
-
Takagi, N.1
Mihara, M.2
Moriya, Y.3
Nishimoto, N.4
Yoshizaki, K.5
Kishimoto, T.6
-
13
-
-
0034967902
-
Severe inflammatory arthritis and lymphadenopathy in the absence of TNF
-
Campbell IK, O'Donnell K, Lawlor KE, Wicks IP. Severe inflammatory arthritis and lymphadenopathy in the absence of TNF. J Clin Invest 2001; 107: 1519-27.
-
(2001)
J Clin Invest
, vol.107
, pp. 1519-1527
-
-
Campbell, I.K.1
O'Donnell, K.2
Lawlor, K.E.3
Wicks, I.P.4
-
14
-
-
0033064097
-
Association of the course of collagen-induced arthritis with distinct patterns of cytokine and chemokine messenger RNA expression
-
Thornton S, Duwel LE, Boivin GP, Ma Y, Hirsch R. Association of the course of collagen-induced arthritis with distinct patterns of cytokine and chemokine messenger RNA expression. Arthritis Rheum 1999; 42: 1109-18.
-
(1999)
Arthritis Rheum
, vol.42
, pp. 1109-1118
-
-
Thornton, S.1
Duwel, L.E.2
Boivin, G.P.3
Ma, Y.4
Hirsch, R.5
-
15
-
-
0031051989
-
Dynamics of proinflammatory cytokine expression in joints of mice with collagen-induced arthritis (CIA)
-
Marinova-Mutafchieva L, Williams RO, Mason LJ, Mauri C, Feldmann M, Maini RN. Dynamics of proinflammatory cytokine expression in joints of mice with collagen-induced arthritis (CIA). Clin Exp Immunol 1997; 107: 507-12.
-
(1997)
Clin Exp Immunol
, vol.107
, pp. 507-512
-
-
Marinova-Mutafchieva, L.1
Williams, R.O.2
Mason, L.J.3
Mauri, C.4
Feldmann, M.5
Maini, R.N.6
-
16
-
-
0035133869
-
Dynamics of early synovial cytokine expression in rodent collagen-induced arthritis. A therapeutic study using a macrophage-deactivating compound
-
Palmblad K, Erlandsson-Harris H, Tracey KJ, Andersson U. Dynamics of early synovial cytokine expression in rodent collagen-induced arthritis. A therapeutic study using a macrophage-deactivating compound. Am J Pathol 2001; 158: 491-500.
-
(2001)
Am J Pathol
, vol.158
, pp. 491-500
-
-
Palmblad, K.1
Erlandsson-Harris, H.2
Tracey, K.J.3
Andersson, U.4
-
17
-
-
0023261356
-
FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro
-
Kino T, Hatanaka H, Miyata S, Inamura N, Nishiyama M, Yajima T et al. FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro. J Antibiotics 1987; 40: 1256-65.
-
(1987)
J Antibiotics
, vol.40
, pp. 1256-1265
-
-
Kino, T.1
Hatanaka, H.2
Miyata, S.3
Inamura, N.4
Nishiyama, M.5
Yajima, T.6
-
18
-
-
0024412228
-
The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes
-
Tocci MJ, Matkovich DA, Collier KA, Kwok P, Dumont F, Lin S et al. The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes. J Immunol 1989; 143: 718-26.
-
(1989)
J Immunol
, vol.143
, pp. 718-726
-
-
Tocci, M.J.1
Matkovich, D.A.2
Collier, K.A.3
Kwok, P.4
Dumont, F.5
Lin, S.6
-
19
-
-
0029797189
-
The mechanism of action of cyclosporin A and FK506
-
Ho S, Clipstone N, Timmermann L, Northrop J, Graef I, Fiorentino D et al. The mechanism of action of cyclosporin A and FK506. Clin Immunol Immunopathol 1996; 80: S40-5.
-
(1996)
Clin Immunol Immunopathol
, vol.80
-
-
Ho, S.1
Clipstone, N.2
Timmermann, L.3
Northrop, J.4
Graef, I.5
Fiorentino, D.6
-
20
-
-
0029145059
-
In vivo model of cartilage degradation - Effects of a matrix metalloproteinase inhibitor
-
Karran EH, Young TJ, Markwell RE, Harper GP. In vivo model of cartilage degradation - effects of a matrix metalloproteinase inhibitor. Ann Rheum Dis 1995; 54: 662-9.
-
(1995)
Ann Rheum Dis
, vol.54
, pp. 662-669
-
-
Karran, E.H.1
Young, T.J.2
Markwell, R.E.3
Harper, G.P.4
-
21
-
-
0023630934
-
The oral dosage form of FK-506
-
Honbo T, Kobayashi M, Hane K, Hata T, Ueda Y. The oral dosage form of FK-506. Transplant Proc 1987;19 Suppl 6: 17-22.
-
(1987)
Transplant Proc
, vol.19
, Issue.6 SUPPL.
, pp. 17-22
-
-
Honbo, T.1
Kobayashi, M.2
Hane, K.3
Hata, T.4
Ueda, Y.5
-
22
-
-
0020955842
-
Models of arthritis and the search for anti-arthritic drugs
-
Billingham MEJ. Models of arthritis and the search for anti-arthritic drugs. Pharmac Ther 1983; 21: 389-428.
-
(1983)
Pharmac Ther
, vol.21
, pp. 389-428
-
-
Billingham, M.E.J.1
-
23
-
-
0027507790
-
Elevated levels of TNF in the joints of adjuvant arthritic rats
-
Smith-Oliver T, Noel LS, Stimpson SS, Yarnall DP, Connolly KM. Elevated levels of TNF in the joints of adjuvant arthritic rats. Cytokine 1993; 5; 298-304.
-
(1993)
Cytokine
, vol.5
, pp. 298-304
-
-
Smith-Oliver, T.1
Noel, L.S.2
Stimpson, S.S.3
Yarnall, D.P.4
Connolly, K.M.5
-
24
-
-
0034125853
-
Temporal expression of inflammatory cytokines and chemokines in rat adjuvant-induced arthritis
-
Szekanecz Z, Halloran MM, Volin MV, Woods JM, Strieter RM, Haines III GK et al. Temporal expression of inflammatory cytokines and chemokines in rat adjuvant-induced arthritis. Arthritis Rheum 2000; 43: 1266-77.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 1266-1277
-
-
Szekanecz, Z.1
Halloran, M.M.2
Volin, M.V.3
Woods, J.M.4
Strieter, R.M.5
Haines III, G.K.6
-
25
-
-
0141531075
-
Differential effects of FK506 and Methotrexate on inflammatory cytokine levels in rat adjuvant-induced arthritis
-
Magari K, Miyata S, Nishigaki F, Ohkubo Y, Mutoh S, Goto T. Differential effects of FK506 and Methotrexate on inflammatory cytokine levels in rat adjuvant-induced arthritis. J Rheumatol 2003; 30: 2193-200.
-
(2003)
J Rheumatol
, vol.30
, pp. 2193-2200
-
-
Magari, K.1
Miyata, S.2
Nishigaki, F.3
Ohkubo, Y.4
Mutoh, S.5
Goto, T.6
-
26
-
-
0347985498
-
Anti-arthritic properties of FK506 on collagen-induced arthritis in rats
-
Magari K, Nishigaki F, Sasakawa T, Ogawa T, Miyata S, Ohkubo Y, et al. Anti-arthritic properties of FK506 on collagen-induced arthritis in rats. Inflamm Res 2003; 52: 524-529.
-
(2003)
Inflamm Res
, vol.52
, pp. 524-529
-
-
Magari, K.1
Nishigaki, F.2
Sasakawa, T.3
Ogawa, T.4
Miyata, S.5
Ohkubo, Y.6
-
27
-
-
0141788311
-
Prevention of the onset and progression of collagen-induced arthritis in rats by the potent p38 mitogen-activated protein kinase inhibitor FR167653
-
Nishikawa N, Myoui A, Tomita T, Takahi K, Nampei A, Yoshikawa H. Prevention of the onset and progression of collagen-induced arthritis in rats by the potent p38 mitogen-activated protein kinase inhibitor FR167653. Arthritis Rheum 2003; 48: 2670-81.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 2670-2681
-
-
Nishikawa, N.1
Myoui, A.2
Tomita, T.3
Takahi, K.4
Nampei, A.5
Yoshikawa, H.6
-
28
-
-
0042121489
-
Efficacy of treatment with glycosaminoglycans on experimental collagen-induced arthritis in rats
-
Campo GM, Avenoso A, Campo S, Ferlazzo AM, Altavilla D, Calatroni A. Efficacy of treatment with glycosaminoglycans on experimental collagen-induced arthritis in rats. Arthritis Res Ther 2003; 5: R122-31.
-
(2003)
Arthritis Res Ther
, vol.5
-
-
Campo, G.M.1
Avenoso, A.2
Campo, S.3
Ferlazzo, A.M.4
Altavilla, D.5
Calatroni, A.6
-
29
-
-
0023884046
-
Immunosuppressive effect of FK506 on collagen-induced arthritis in rats
-
Inamura N, Hashimoto M, Nakahara K, Aoki H, Yamaguchi I, Kohsaka M. Immunosuppressive effect of FK506 on collagen-induced arthritis in rats. Clin Immunol Immunopathol 1988; 46: 82-90.
-
(1988)
Clin Immunol Immunopathol
, vol.46
, pp. 82-90
-
-
Inamura, N.1
Hashimoto, M.2
Nakahara, K.3
Aoki, H.4
Yamaguchi, I.5
Kohsaka, M.6
-
30
-
-
0036674871
-
Efficacy of tacrolimus in rheumatoid arthritis patients who have been treated unsuccessfully with methotrexate. A six-month, double-blind, randomized, dose-ranging study
-
Furst DE, Saag K, Fleischmann MR, Sherrer Y, Block JA, Schnitzer T et al. Efficacy of tacrolimus in rheumatoid arthritis patients who have been treated unsuccessfully with methotrexate. A six-month, double-blind, randomized, dose-ranging study. Arthritis Rheum 2002; 46: 2020-8.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 2020-2028
-
-
Furst, D.E.1
Saag, K.2
Fleischmann, M.R.3
Sherrer, Y.4
Block, J.A.5
Schnitzer, T.6
-
31
-
-
0038637479
-
Calcineurin inhibitors exert rapid reduction of inflammatory pain in rat adjuvant-induced arthritis
-
Magari K, Miyata S, Ohkubo Y, Mutoh S, Goto T. Calcineurin inhibitors exert rapid reduction of inflammatory pain in rat adjuvant-induced arthritis. Br J Pharmacol 2003; 139: 927-34.
-
(2003)
Br J Pharmacol
, vol.139
, pp. 927-934
-
-
Magari, K.1
Miyata, S.2
Ohkubo, Y.3
Mutoh, S.4
Goto, T.5
-
32
-
-
0033852795
-
FK506 potently inhibits T cell activation induced TNF-α and IL-1β production in vitro by human peripheral blood mononuclear cells
-
Sakuma S, Kato Y, Nishigaki F, Sasakawa T, Magari K, Miyata S et al. FK506 potently inhibits T cell activation induced TNF-α and IL-1β production in vitro by human peripheral blood mononuclear cells. Br J Pharmacol 2000; 130: 1655-63.
-
(2000)
Br J Pharmacol
, vol.130
, pp. 1655-1663
-
-
Sakuma, S.1
Kato, Y.2
Nishigaki, F.3
Sasakawa, T.4
Magari, K.5
Miyata, S.6
-
33
-
-
0035108541
-
Effects of FK506 and other immunosuppressive anti-rheumatic agents on T cell activation mediated IL-6 and IgM production in vitro
-
Sakuma S, Kato Y, Nishigaki F, Magari K, Miyata S, Ohkubo Y, et al. Effects of FK506 and other immunosuppressive anti-rheumatic agents on T cell activation mediated IL-6 and IgM production in vitro. Int Immunopharmacol 2001; 1: 749-57.
-
(2001)
Int Immunopharmacol
, vol.1
, pp. 749-757
-
-
Sakuma, S.1
Kato, Y.2
Nishigaki, F.3
Magari, K.4
Miyata, S.5
Ohkubo, Y.6
-
34
-
-
0030808459
-
Suppression of collagen-induced arthritis through adenovirus-mediated transfer of a modified tumor necrosis factor α receptor gene
-
Le CH, Nicolson AG, Morales A, Sewell KL. Suppression of collagen-induced arthritis through adenovirus-mediated transfer of a modified tumor necrosis factor α receptor gene. Arthritis Rheum 1997; 40: 1662-9.
-
(1997)
Arthritis Rheum
, vol.40
, pp. 1662-1669
-
-
Le, C.H.1
Nicolson, A.G.2
Morales, A.3
Sewell, K.L.4
-
35
-
-
0029875804
-
Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice. A comparative study using anti-TNFα, anti-IL-1α/ β, and IL-1Ra
-
Joosten LAB, Helsen MMA, van de Loo FAJ, van den Berg WB. Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice. A comparative study using anti-TNFα, anti-IL-1α/β, and IL-1Ra. Arthritis Rheum 1996; 39: 797-809.
-
(1996)
Arthritis Rheum
, vol.39
, pp. 797-809
-
-
Joosten, L.A.B.1
Helsen, M.M.A.2
Van De Loo, F.A.J.3
Van Den Berg, W.B.4
-
36
-
-
0032752705
-
IL-1αβ blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-α blockade only ameliorates joint inflammation
-
Joosten LAB, Helsen MMA, Saxne T, van de Loo FAJ, Heinegård D, van den Berg WB. IL-1αβ blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-α blockade only ameliorates joint inflammation. J Immunol 1999; 163: 5049-55.
-
(1999)
J Immunol
, vol.163
, pp. 5049-5055
-
-
Joosten, L.A.B.1
Helsen, M.M.A.2
Saxne, T.3
Van De Loo, F.A.J.4
Heinegård, D.5
Van Den Berg, W.B.6
-
38
-
-
0029166052
-
Role of cytokines in bone resorption
-
Manolagas SC. Role of cytokines in bone resorption. Bone 1995; 17 Suppl 2: 63S-7S.
-
(1995)
Bone
, vol.17
, Issue.2 SUPPL.
-
-
Manolagas, S.C.1
|