Severe inflammatory arthritis and lymphadenopathy in the absence of TNF

Journal of Clinical Investigation

Volumn 107, Issue 12, 2001, Pages 1519-1527

  Campbell, I K ^a   O'Donnell, K ^a   Lawlor, K E ^a   Wicks, I P ^a  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; CYTOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE SEVERITY; LYMPH NODE CELL; LYMPHADENOPATHY; LYMPHOCYTE PROLIFERATION; NONHUMAN; PRIORITY JOURNAL; SPLENOMEGALY; T LYMPHOCYTE;

EID: 0034967902     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI12724     Document Type: Article

References (44)

1. The tumor necrosis factor ligand and receptor families
2. Inhibitory effect of TNFα antibodies on synovial cell interleukin-1 production in rheumatoid arthritis
3. Rheumatoid arthritis
4. Collagen-induced arthritis, an animal model of autoimmunity
5. Interleukin 6 is required for the development of collagen-induced arthritis
6. High susceptibility to collagen-induced arthritis in mice lacking IFN-γ receptors
7. Attenuation of collagen-induced arthritis in 55-kDa TNF receptor type 1 (TNFR1)1gG1-treated and TNFR1-deficient mice
8. Reduced susceptibility to collagen-induced arthritis in mice deficient in intercellular adhesion molecule-1
9. Reduced incidence and severity of collagen-induced arthritis in interleukin-12-deficient mice
10. Mice lacking mature T and B lymphocytes develop arthritic lesions after immunization with type II collagen
11. Induction and suppression of collagen-induced arthritis is dependent on distinct Fcγ receptors
12. b) mice: New insights into an important disease model of rheumatoid arthritis
13. Immune and inflammatory responses in TNFα-deficient mice: A critical requirement for TNFα in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centres, and in the maturation of the humoral immune response
14. Characterization of tumor necrosis factor-deficient mice
15. Distinct roles for lymphotoxin-α and tumor necrosis factor in organogenesis and spatial organization of lymphoid tissue
16. Distinct roles for the NF-κB1 (p50) and c-Rel transcription factors in inflammatory arthritis
17. Molecular and cellular mediators of IL-1-dependent, acute inflammatory arthritis
18. Protection from collagen-induced arthritis in granulocyte-macrophage colony-stimulating factor-deficient mice
19. Type II collagen-induced murine arthritis. I. Induction and perpetuation of arthritis require synergy between humoral and cell-mediated immunity
20. Immunological memory
21. Induction of an acute erosive monoarticular arthritis in mice by interleukin-1 and methylated bovine serum albumin
22. Localization of tumor necrosis factor α in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis
23. Detection of tumor necrosis factor α but not tumor necrosis factor β in rheumatoid arthritis synovial fluid and serum
24. Inhibition of the production and effects of interleukin-1 and tumor necrosis factor α in rheumatoid arthritis
25. Role of cytokines in rheumatoid arthritis
26. Transgenic mice expressing human tumour necrosis factor: A predictive genetic model of arthritis
27. Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis
28. Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice. A comparative study using anti-TNFα anti-IL-1α/β, and IL-1Ra
29. Influence of a recombinant human soluble tumor necrosis factor receptor Fc fusion protein on type II collagen-induced arthritis in mice
30. Anti-TNFα therapy of rheumatoid arthritis: What have we learned?
31. Etanercept therapy in rheumatoid arthritis. A randomized, controlled trial
32. Tumour necrosis factor-α in murine autoimmune 'lupus' nephritis
33. Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): Similarities between TNF-α and interleukin 1
34. Accelerated autoimmunity and lupus nephritis in NZB mice with an engineered heterozygous deficiency in tumor necrosis factor
35. TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination
36. Failure to suppress the expansion of the activated CD4 T cell population in interferon γ-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis
37. Biphasic effect of interferon-γ in murine collagen-induced arthritis
38. Dual role of IL-12 in early and late stages of murine collagen type II arthritis
39. Increased peripheral T cell reactivity to microbial antigens and collagen type II in rheumatoid arthritis after treatment with soluble TNFα receptors
40. Current evidence for the induction of autoimmune rheumatic manifestations by cytokine therapy
41. Mature T lymphocyte apoptosis - Immune regulation in a dynamic and unpredictable antigenic environment
42. Tumor necrosis factor: A master-regulator of leukocyte movement
43. Deactivation of vascular endothelium by monoclonal anti-tumor necrosis factor α antibody in rheumatoid arthritis
44. Decrease in cellularity and expression of adhesion molecules by anti-tumor necrosis factor α monoclonal antibody treatment in patients with rheumatoid arthritis