A Tale of Two Tumor Targets: Topoisomerase I and Tubulin. The Wall and Wani Contribution to Cancer Chemotherapy

Journal of Natural Products

Volumn 67, Issue 2, 2004, Pages 232-244

  Cragg, Gordon M ^a,b   Newman, David J ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 FORMYLAMINO 12,13 DIHYDRO 1,11 DIHYDROXY 5H INDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE 5,7(6H) DIONE 13 GLUCOSIDE; 7 ETHYL 10 HYDROXYCAMPTOTHECIN; A 105972; A 259745; A 289099; A 293620; A 305754; A 318315; ALS 559; AM 132; ANTIMITOTIC AGENT; ANTINEOPLASTIC AGENT; AVE 8062A; AVE 8063A; BELOTECAN; BMS 184476; BMS 185660; BMS 188797; BMS 247615; BMS 250749; BMS 275183; BN 80927; BPR OY 007; BTO 956; CAMPTOTHECIN; CZ 112; CZ 48; D 24851; D 64131; D 82318; D51 1456; DB 148; DB 158; DB 174; DB 202; DB 67; DDE 313; DICTYOSTATIN 1; DISCODERMOLIDE; DJ 927; DNA TOPOISOMERASE; DNA TOPOISOMERASE INHIBITOR; DOCETAXEL; DOLASTATIN 10; DRF 1042; DRF 1644; DRF 3188; DZ 3358; E 7389; ELEUTHEROBIN; EPOTHILONE DERIVATIVE; ER 34410; ERBULOZOLE; F 11782; F 12167; FR 182877; HALICHONDRIN B; IDN 5005; IDN 5390; ILX 651; IRINOTECAN; J 109404; J 109534; JIMB 01; KARENITECIN; LAULIMALIDE; LE SN38; LS 4477; LS 4559; LS 4559 P; LU 223651; LURTOTECAN; N [2 [(4 HYDROXYPHENYL)AMINO] 3 PYRIDINYL] 4 METHOXYBENZENESULFONAMIDE; NATURAL PRODUCT; NAVELBINE; NOSCAPINE; NSC 12983; NSC 639829; NSC 647752; ONCO TCS; PACLITAXEL; PNU 105298; PNU 166945; RPR 109881A; RPR 112378; RUBITECAN; S 2512; S 2513; S 2521; S 2526; SARCODICTYIN; SB T 1011; SB T 1212; SDZ LAV 694; SSR 250411; STA 5312; T 138026; T 138067; T 3782; T 900607; TALTOBULIN; TL 00139; TOPOTECAN; TUBULIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VINBLASTINE; VINCA ALKALOID; VINCRISTINE; VINDESINE; XR 11576; XR 11612; XR 5944;

ANTINEOPLASTIC ACTIVITY; CANCER CHEMOTHERAPY; DRUG EFFICACY; DRUG STRUCTURE; DRUG TARGETING; MICROTUBULE ASSEMBLY; REVIEW;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIOLOGICAL FACTORS; CAMPTOTHECIN; DNA TOPOISOMERASES, TYPE I; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; MOLECULAR STRUCTURE; PACLITAXEL; PLANTS, MEDICINAL; TUBULIN MODULATORS;

VINCA;

EID: 1442310087     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np030420c     Document Type: Review

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