-
1
-
-
0029896530
-
Role of leptin in the neuroendocrine response to fasting
-
Ahima RS, Prabakaran D, Mantzoros C et al. Role of leptin in the neuroendocrine response to fasting. Nature 1996; 382: 250-252
-
(1996)
Nature
, vol.382
, pp. 250-252
-
-
Ahima, R.S.1
Prabakaran, D.2
Mantzoros, C.3
-
2
-
-
0034640508
-
Activation of downstream signals by the long form of the leptin receptor
-
Banks AS, Davis SM, Bates SH, Jr. Myers MG. Activation of downstream signals by the long form of the leptin receptor. J Biol Chem 2000; 275: 14563-14572
-
(2000)
J Biol Chem
, vol.275
, pp. 14563-14572
-
-
Banks, A.S.1
Davis, S.M.2
Bates, S.H.3
Myers Jr., M.G.4
-
3
-
-
13844304602
-
Delayed resolution of acute inflammation during zymosan-induced arthritis in leptin-deficient mice
-
Bernotiene E, Palmer G, Talabot-Ayer D, Szalay-Quinodoz I, Aubert ML, Gabay C. Delayed resolution of acute inflammation during zymosan-induced arthritis in leptin-deficient mice. Arthritis Res Ther 2004; 6: R256-263
-
(2004)
Arthritis Res Ther
, vol.6
-
-
Bernotiene, E.1
Palmer, G.2
Talabot-Ayer, D.3
Szalay-Quinodoz, I.4
Aubert, M.L.5
Gabay, C.6
-
4
-
-
0037080196
-
Leptin signaling deficiency impairs humoral and cellular immune responses and attenuates experimental arthritis
-
Busso N, So A, Chobaz-Peclat V et al. Leptin signaling deficiency impairs humoral and cellular immune responses and attenuates experimental arthritis. J Immunol 2002; 168: 875-882
-
(2002)
J Immunol
, vol.168
, pp. 875-882
-
-
Busso, N.1
So, A.2
Chobaz-Peclat, V.3
-
5
-
-
0018139377
-
Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice
-
Coleman DL. Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 1978; 14: 141-148
-
(1978)
Diabetologia
, vol.14
, pp. 141-148
-
-
Coleman, D.L.1
-
6
-
-
0030793449
-
Ligand-independent dimerization of the extracellular domain of the leptin receptor and determination of the stoichiometry of leptin binding
-
Devos R, Guisez Y, Van der Heyden J et al. Ligand-independent dimerization of the extracellular domain of the leptin receptor and determination of the stoichiometry of leptin binding. J Biol Chem 1997; 272: 18304-18310
-
(1997)
J Biol Chem
, vol.272
, pp. 18304-18310
-
-
Devos, R.1
Guisez, Y.2
Van Der Heyden, J.3
-
7
-
-
0345688661
-
Leptin induces growth hormone secretion from peripheral blood mononuclear cells via a protein kinase C-and nitric oxide-dependent mechanism
-
Dixit VD, Mielenz M, Taub DD, Parvizi N. Leptin induces growth hormone secretion from peripheral blood mononuclear cells via a protein kinase C-and nitric oxide-dependent mechanism. Endocrinology 2003; 144: 5595-603
-
(2003)
Endocrinology
, vol.144
, pp. 5595-5603
-
-
Dixit, V.D.1
Mielenz, M.2
Taub, D.D.3
Parvizi, N.4
-
8
-
-
0034058378
-
Leptin-defident (ob/ob) mice are protected from T cell-mediated hepatotoxicity: Role of tumor necrosis factor alpha and 1L-18
-
Faggioni R, Jones-Carson J, Reed DA et al. Leptin-defident (ob/ob) mice are protected from T cell-mediated hepatotoxicity: role of tumor necrosis factor alpha and 1L-18. Proc Natl Acad Sci U S A 2000; 97: 2367-2372
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 2367-2372
-
-
Faggioni, R.1
Jones-Carson, J.2
Reed, D.A.3
-
9
-
-
0033782028
-
Leptin in the regulation of immunity, inflammation, and hematopoiesis
-
Fantuzzi G, Faggioni R. Leptin in the regulation of immunity, inflammation, and hematopoiesis. J Leukoc Biol 2000; 68: 437-446
-
(2000)
J Leukoc Biol
, vol.68
, pp. 437-446
-
-
Fantuzzi, G.1
Faggioni, R.2
-
10
-
-
0036800760
-
Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
-
Farooqi IS, Matarese G, Lord GM et al. Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. J Clin Invest 2002; 110: 1093-1103
-
(2002)
J Clin Invest
, vol.110
, pp. 1093-1103
-
-
Farooqi, I.S.1
Matarese, G.2
Lord, G.M.3
-
11
-
-
0031886385
-
Localization of leptin binding domain in the leptin receptor
-
Fong TM, Huang RR, Tota MR et al. Localization of leptin binding domain in the leptin receptor. Mol Pharmacol 1998; 53: 234-240
-
(1998)
Mol Pharmacol
, vol.53
, pp. 234-240
-
-
Fong, T.M.1
Huang, R.R.2
Tota, M.R.3
-
12
-
-
0029952911
-
Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells
-
Gainsford T, Willson TA, Metcalf D et al. Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells. Proc Natl Acad Sci U S A 1996; 93: 14564-14568
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 14564-14568
-
-
Gainsford, T.1
Willson, T.A.2
Metcalf, D.3
-
13
-
-
0034950575
-
Leptin is a growth factor for colonic epithelial cells
-
Hardwick JCH, Van den Brink GR, Offerhaus GJ, Van Deventer SJH. Peppelenbosch MP. Leptin is a growth factor for colonic epithelial cells. Gastroenterology 2001; 121: 79-90
-
(2001)
Gastroenterology
, vol.121
, pp. 79-90
-
-
Hardwick, J.C.H.1
Van Den Brink, G.R.2
Offerhaus, G.J.3
Van Deventer, S.J.H.4
Peppelenbosch, M.P.5
-
14
-
-
17744388106
-
Transcellular transport of leptin by the short leptin receptor isoform ObRa in Madin-Darby Canine Kidney cells
-
Hileman SM, Tornoe J, Flier JS, Bjorbaek C. Transcellular transport of leptin by the short leptin receptor isoform ObRa in Madin-Darby Canine Kidney cells. Endocrinology 2000; 141: 1955-1961
-
(2000)
Endocrinology
, vol.141
, pp. 1955-1961
-
-
Hileman, S.M.1
Tornoe, J.2
Flier, J.S.3
Bjorbaek, C.4
-
15
-
-
0035794211
-
Modulation of circulating leptin levels by its soluble receptor
-
Huang L, Wang Z, Li C. Modulation of circulating leptin levels by its soluble receptor. J Biol Chem 2001; 276: 6343-6349
-
(2001)
J Biol Chem
, vol.276
, pp. 6343-6349
-
-
Huang, L.1
Wang, Z.2
Li, C.3
-
16
-
-
2442618838
-
The weight of leptin in immunity
-
La Cava A, Matarese G. The weight of leptin in immunity. Nat Rev Immunol 2004; 4: 371-379
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 371-379
-
-
La Cava, A.1
Matarese, G.2
-
17
-
-
0032572722
-
Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
-
Lord GM, Matarese G, Howard JK, Baker RJ, Bloom SR, Lechler RI. Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression. Nature 1998; 394: 897-901
-
(1998)
Nature
, vol.394
, pp. 897-901
-
-
Lord, G.M.1
Matarese, G.2
Howard, J.K.3
Baker, R.J.4
Bloom, S.R.5
Lechler, R.I.6
-
18
-
-
0036697779
-
Leptin inhibits the anti-CDS-driven proliferation of peripheral blood T cells but enhances the production of proinflammatory cytokines
-
Lord GM, Matarese G, Howard JK, Bloom SR, Lechler RI. Leptin inhibits the anti-CDS-driven proliferation of peripheral blood T cells but enhances the production of proinflammatory cytokines. J Leukoc Biol 2002; 72: 330-338
-
(2002)
J Leukoc Biol
, vol.72
, pp. 330-338
-
-
Lord, G.M.1
Matarese, G.2
Howard, J.K.3
Bloom, S.R.4
Lechler, R.I.5
-
19
-
-
0037090316
-
Leptin-deficient mice exhibit impaired host defense in gram-negative pneumonia
-
Mancuso P, Gottschalk A, Phare SM, Peters-Golden M, Lukacs NW, Huffnagle GB. Leptin-deficient mice exhibit impaired host defense in gram-negative pneumonia. J Immunol 2002; 168: 4018-4024
-
(2002)
J Immunol
, vol.168
, pp. 4018-4024
-
-
Mancuso, P.1
Gottschalk, A.2
Phare, S.M.3
Peters-Golden, M.4
Lukacs, N.W.5
Huffnagle, G.B.6
-
20
-
-
0018148843
-
Impairment of cell-mediated immunity in mutation diabetic mice (db/db)
-
Mandel MA, Mahmoud AA. Impairment of cell-mediated immunity in mutation diabetic mice (db/db). J Immunol 1978; 120: 1375-1377
-
(1978)
J Immunol
, vol.120
, pp. 1375-1377
-
-
Mandel, M.A.1
Mahmoud, A.A.2
-
21
-
-
0035873418
-
Requirement for leptin in the induction and progression of autoimmune encephalomyelitis
-
Matarese G, Di Giacomo A, Sanna V et al. Requirement for leptin in the induction and progression of autoimmune encephalomyelitis. J Immunol 2001; 166: 5909-5916
-
(2001)
J Immunol
, vol.166
, pp. 5909-5916
-
-
Matarese, G.1
Di Giacomo, A.2
Sanna, V.3
-
22
-
-
0034998907
-
Leptin potentiates experimental autoimmune encephalomyelitis in SJL female mice and confers susceptibility to males
-
Matarese G, Sanna V, Di Giacomo A et al. Leptin potentiates experimental autoimmune encephalomyelitis in SJL female mice and confers susceptibility to males. Eur J Immunol 2001; 31: 1324-1332
-
(2001)
Eur J Immunol
, vol.31
, pp. 1324-1332
-
-
Matarese, G.1
Sanna, V.2
Di Giacomo, A.3
-
23
-
-
0030878110
-
Congenital leptin deficiency is associated with severe early-onset obesity in humans
-
Montague CT, Farooqi IS, Whitehead JP et al. Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 1997; 387: 903-908
-
(1997)
Nature
, vol.387
, pp. 903-908
-
-
Montague, C.T.1
Farooqi, I.S.2
Whitehead, J.P.3
-
24
-
-
0037371715
-
Leptin mediates Clostridium difficile toxin A-induced enteritis in mice
-
Mykoniatis A, Anton PM, Wlk M et al. Leptin mediates Clostridium difficile toxin A-induced enteritis in mice. Gastroenterology 2003; 124: 683-691
-
(2003)
Gastroenterology
, vol.124
, pp. 683-691
-
-
Mykoniatis, A.1
Anton, P.M.2
Wlk, M.3
-
25
-
-
0033304576
-
Human leptin deficiency caused by a missense mutation: Multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects
-
Ozata M, Ozdemir IC, Licinio J. Human leptin deficiency caused by a missense mutation: multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects. J Clin Endocrinol Metab 1999; 84: 3686-3695
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 3686-3695
-
-
Ozata, M.1
Ozdemir, I.C.2
Licinio, J.3
-
26
-
-
0036319605
-
Leptin levels are associated with immune response in malnourished infants
-
Palacio A, Lopez M, Perez-Bravo F et al. Leptin levels are associated with immune response in malnourished infants. J Clin Endocrinol Metab 2002; 87: 3040-3046
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 3040-3046
-
-
Palacio, A.1
Lopez, M.2
Perez-Bravo, F.3
-
27
-
-
0035838266
-
Human leptin signaling in human peripheral blood mononuclear cells: Activation of the JAK-STAT pathway
-
Sanchez-Margalet V, Martin-Romero C. Human leptin signaling in human peripheral blood mononuclear cells: activation of the JAK-STAT pathway. Cell Immunol 2001; 211: 30-36
-
(2001)
Cell Immunol
, vol.211
, pp. 30-36
-
-
Sanchez-Margalet, V.1
Martin-Romero, C.2
-
28
-
-
0037241113
-
Leptin surge precedes onset of autoimmune encephalomyelitis and correlates with development of pathogenic T cell responses
-
Sanna V, Di Giacomo A, La Cava A et al. Leptin surge precedes onset of autoimmune encephalomyelitis and correlates with development of pathogenic T cell responses. J Clin Invest 2003; 111: 241-250
-
(2003)
J Clin Invest
, vol.111
, pp. 241-250
-
-
Sanna, V.1
Di Giacomo, A.2
La Cava, A.3
-
29
-
-
0036181471
-
Leptin deficiency, not obesity, protects mice from Con A-induced hepatitis
-
Siegmund B, Lear-Kaul KC, Faggioni R, Fantuzzi G. Leptin deficiency, not obesity, protects mice from Con A-induced hepatitis. Eur J Immunol 2002; 32: 552-560
-
(2002)
Eur J Immunol
, vol.32
, pp. 552-560
-
-
Siegmund, B.1
Lear-Kaul, K.C.2
Faggioni, R.3
Fantuzzi, G.4
-
30
-
-
0036080142
-
Leptin: A pivotal mediator of intestinal inflammation in mice
-
Siegmund B, Lehr HA, Fantuzzi G. Leptin: a pivotal mediator of intestinal inflammation in mice. Gastroenterology 2002; 122: 2011-2025
-
(2002)
Gastroenterology
, vol.122
, pp. 2011-2025
-
-
Siegmund, B.1
Lehr, H.A.2
Fantuzzi, G.3
-
31
-
-
3042661014
-
Leptin receptor expression on T lymphocytes modulates chronic intestinal inflammation in mice
-
Siegmund B, Sennello JA, Jones-Carson J et al. Leptin receptor expression on T lymphocytes modulates chronic intestinal inflammation in mice. Gut 2004; 53: 965-972
-
(2004)
Gut
, vol.53
, pp. 965-972
-
-
Siegmund, B.1
Sennello, J.A.2
Jones-Carson, J.3
-
32
-
-
0032014836
-
A leptin missense mutation associated with hypogonadism and morbid obesity
-
Strobel A, Issad T, Camoin L et al. A leptin missense mutation associated with hypogonadism and morbid obesity. Nat Genet 1998; 18: 213-215
-
(1998)
Nat Genet
, vol.18
, pp. 213-215
-
-
Strobel, A.1
Issad, T.2
Camoin, L.3
-
33
-
-
2442654859
-
Identification and expression cloning of a leptin receptor, OB-R
-
Tartaglia LA, Dembski M, Weng X et al. Identification and expression cloning of a leptin receptor, OB-R. Cell 1995; 83: 1263-1271
-
(1995)
Cell
, vol.83
, pp. 1263-1271
-
-
Tartaglia, L.A.1
Dembski, M.2
Weng, X.3
-
34
-
-
0030942844
-
The leptin receptor
-
Tartaglia LA. The leptin receptor. J Biol Chem 1997; 272: 6093-6096
-
(1997)
J Biol Chem
, vol.272
, pp. 6093-6096
-
-
Tartaglia, L.A.1
-
35
-
-
1542379725
-
Leptin-deficient mice are protected from accelerated nephrotoxic nephritis
-
Tarzi RM, Cook HT, Jackson I, Pusey CD, Lord GM. Leptin-deficient mice are protected from accelerated nephrotoxic nephritis. Am J Pathol 2004; 164: 385-390
-
(2004)
Am J Pathol
, vol.164
, pp. 385-390
-
-
Tarzi, R.M.1
Cook, H.T.2
Jackson, I.3
Pusey, C.D.4
Lord, G.M.5
-
36
-
-
0001513966
-
Obesity increases sensitivity to endotoxin liver injury: Implications for the pathogenesis of steatohepatitis
-
Yang SQ, Lin HZ, Lane MD, Clemens M, Diehl AM. Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis. Proc Natl Acad Sci U S A 1997; 94: 2557-2562
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 2557-2562
-
-
Yang, S.Q.1
Lin, H.Z.2
Lane, M.D.3
Clemens, M.4
Diehl, A.M.5
-
37
-
-
0037862102
-
The ins and outs of leptin receptor activation
-
Zabeau L, Lavens D, Peelman F, Eyckerman S, Vandekerckhove J, Tavernier J. The ins and outs of leptin receptor activation. FEBS Lett 2003; 546: 45-50
-
(2003)
FEBS Lett
, vol.546
, pp. 45-50
-
-
Zabeau, L.1
Lavens, D.2
Peelman, F.3
Eyckerman, S.4
Vandekerckhove, J.5
Tavernier, J.6
-
38
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994; 372: 425-432
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
|