Leptin is a growth factor for colonic epithelial cells

Gastroenterology

Volumn 121, Issue 1, 2001, Pages 79-90

  Hardwick, James C H ^a   Van Den Brink, Gijs R ^a   Offerhaus, G J ^a   Van Deventer, Sander J H ^a   Peppelenbosch, Maikel P ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR; LEPTIN; LEPTIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE;

ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CELL STRAIN HT29; COLON MUCOSA; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0034950575     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/gast.2001.25490     Document Type: Article

References (50)

1. Colorectal cancer: Molecules and populations
2. Leptin and the regulation of body weight in mammals
3. Studies in the diabetic mutant mouse. VI. Evolution of glomerular lesions and associated proteinuria
4. Leptin stimulates proliferation and TGF-beta expression in renal glomerular endothelial cells: Potential role in glomerulosclerosis
5. Leptin receptor signal transduction: OBRa and OBRb of fa type
6. A short form of leptin receptor performs signal transduction
7. Leptin action in intestinal cells
8. Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
9. Expression of leptin receptor in lung: Leptin as a growth factor
10. Leptin induces oxidative stress in human endothelial cells
11. Detection of Ob-receptor in human adrenal neoplasms and effect of leptin on adrenal cell proliferation
12. Human leptin stimulates proliferation and activation of human circulating monocytes
13. The role of leptin in human obesity and disease: A review of current evidence
14. The effect of exercise training on leptin levels in obese males
15. Cigarette smoking, alcohol use, and physical activity in relation to serum leptin levels in a multiethnic population: The Miami Community Health Study
16. Rapid leptin decrease in immediate post-exercise recovery
17. Exercise training down-regulates ob gene expression in the genetically obese SHHF/Mcc-fa(cp) rat
18. Plasma leptin concentrations in obese children: Changes during 4-mo periods with and without physical training
19. Prolonged exercise decreases serum leptin concentrations
20. Serum leptin levels in male marathon athletes before and after the marathon run
21. Effects of mild aerobic exercise and a mild hypocaloric diet on plasma leptin in sedentary women
22. Regulation of average 24h human plasma leptin level; the influence of exercise and physiological changes in energy balance
23. Voluntary wheel running decreases adipose tissue mass and expression of leptin mRNA in Osborne-Mendel rats
24. Identification and expression cloning of a leptin receptor, OB-R
25. Novel B219/OB receptor isoforms: Possible role of leptin in hematopoiesis and reproduction
26. Effects of the obese gene product on body weight regulation in ob/ob mice
27. Leptin receptor in human term placenta: In situ hybridization and immunohistochemical localization
28. Peanut lectin: A mitogen for normal human colonic epithelium and human HT29 colorectal cancer cells
29. Colon cancer: A review of the epidemiology
30. Body mass index and colon cancer in a national sample of adult US men and women
31. Insulin and colon cancer
32. Epidemiology of colorectal cancer revisited: Are serum triglycerides and/or plasma glucose associated with risk?
33. Glycosylated hemoglobin and risk of colorectal cancer and adenoma (United States)
34. Small weight gain is not associated with development of insulin resistance in healthy, physically active individuals
35. Nutritional regulation of leptin in humans
36. Energy balance and cancers
37. Mechanisms of diet and colon carcinogenesis
38. Energy intake, overweight, physical exercise and colorectal cancer risk
39. Effect of caloric restriction on colonic proliferation in obese persons: Implications for colon cancer prevention
40. Serum leptin concentration and fuel homeostasis in healthy man
41. Obesity and colorectal adenomatous polyps
42. Physical activity, obesity, and risk for colon cancer and adenoma in men
43. Involvement of gonadal steroid hormone disturbance in altered prolactin receptor gene expression in the liver of diabetic mice
44. The db/db mouse, a model for diabetic dyslipidemia: Molecular characterization and effects of Western diet feeding
45. Reproduction, endogenous and exogenous sex hormones, and colon cancer: A review and hypothesis
46. Epidemiology of colorectal cancer revisited: Are serum triglycerides and/or plasma glucose associated with risk?
47. Expression of the insulin-like growth factors and their receptors in adenocarcinoma of the colon
48. Insulinlike growth factors and binding proteins in colon cancer
49. Transforming growth factors and related peptides in gastrointestinal neoplasia
50. Colorectal neoplasia in acromegaly