메뉴 건너뛰기




Volumn 151, Issue 2, 2005, Pages 53-62

Regulation of CYP3A genes in the human respiratory tract

Author keywords

Cytochrome P450; Gene regulation; Human lung; Nuclear receptor; Xenobiotic metabolism

Indexed keywords

BILE ACID; CARCINOGEN; CELL NUCLEUS RECEPTOR; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450 3A; CYTOCHROME P450 3A4; CYTOCHROME P450 3A43; CYTOCHROME P450 3A5; CYTOCHROME P450 3A7; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HEPATIC NUCLEAR FACTOR 4 ALPHA; LIGAND; PREGNANE X RECEPTOR; STEROID; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 13444293231     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2003.12.007     Document Type: Review
Times cited : (48)

References (55)
  • 1
    • 0032924934 scopus 로고    scopus 로고
    • Cytochrome P-450 3A4: Regulation and role in drug metabolism
    • F.P. Guengerich Cytochrome P-450 3A4: regulation and role in drug metabolism Annu. Rev. Pharmacol. Toxicol. 39 1999 1 17
    • (1999) Annu. Rev. Pharmacol. Toxicol. , vol.39 , pp. 1-17
    • Guengerich, F.P.1
  • 3
    • 0031810509 scopus 로고    scopus 로고
    • Developmental expression of cytochrome P450 enzymes in human liver
    • J. Hakkola, E. Tanaka, and O. Pelkonen Developmental expression of cytochrome P450 enzymes in human liver Pharmacol. Toxicol. 82 1998 209 217
    • (1998) Pharmacol. Toxicol. , vol.82 , pp. 209-217
    • Hakkola, J.1    Tanaka, E.2    Pelkonen, O.3
  • 4
    • 0036156595 scopus 로고    scopus 로고
    • The ontogeny of human drug-metabolising enzymes: Phase I oxidative enzymes
    • R.N. Hines, and D.G. McCarver The ontogeny of human drug-metabolising enzymes: phase I oxidative enzymes J. Pharmacol. Exp. Ther. 300 2002 355 360
    • (2002) J. Pharmacol. Exp. Ther. , vol.300 , pp. 355-360
    • Hines, R.N.1    McCarver, D.G.2
  • 5
    • 0035135258 scopus 로고    scopus 로고
    • CDNA cloning and initial characterization of CYP3 A43, a novel human cytochrome P450
    • T.L. Domanski, C. Finta, J.R. Halpert, and P.G. Zaphiropoulos cDNA cloning and initial characterization of CYP3 A43, a novel human cytochrome P450 Mol. Pharmacol. 59 2001 386 392
    • (2001) Mol. Pharmacol. , vol.59 , pp. 386-392
    • Domanski, T.L.1    Finta, C.2    Halpert, J.R.3    Zaphiropoulos, P.G.4
  • 10
  • 14
    • 0034975420 scopus 로고    scopus 로고
    • Hepatic cytochrome P450 regulation in disease states
    • P.-Y. Chen, and E.T. Morgan Hepatic cytochrome P450 regulation in disease states Curr. Drug Metab. 2 2001 155 183
    • (2001) Curr. Drug Metab. , vol.2 , pp. 155-183
    • Chen, P.-Y.1    Morgan, E.T.2
  • 15
    • 0029820670 scopus 로고    scopus 로고
    • Constitutive expression of hepatic cytochrome P450 genes
    • F.J. Gonzalez, and Y.H. Lee Constitutive expression of hepatic cytochrome P450 genes FASEB J. 10 1996 1112 1117
    • (1996) FASEB J. , vol.10 , pp. 1112-1117
    • Gonzalez, F.J.1    Lee, Y.H.2
  • 16
    • 0037450505 scopus 로고    scopus 로고
    • Regulation of P450 genes by liver-enriched transcription factors and nuclear receptors
    • T.E. Akiyama, and F.J. Gonzalez Regulation of P450 genes by liver-enriched transcription factors and nuclear receptors Biochim. Biophys. Acta 1619 2003 223 234
    • (2003) Biochim. Biophys. Acta , vol.1619 , pp. 223-234
    • Akiyama, T.E.1    Gonzalez, F.J.2
  • 17
    • 0036830875 scopus 로고    scopus 로고
    • Down-regulation of human CYP3A4 by the inflammatory signal interleukin-6: Molecular mechanism and transcription factors involved
    • R. Jover, R. Bort, M.J. Gomez-Lechon, and J.V. Castell Down-regulation of human CYP3A4 by the inflammatory signal interleukin-6: molecular mechanism and transcription factors involved FASEB J. 16 2002 1799 1801
    • (2002) FASEB J. , vol.16 , pp. 1799-1801
    • Jover, R.1    Bort, R.2    Gomez-Lechon, M.J.3    Castell, J.V.4
  • 18
  • 20
    • 12344309738 scopus 로고    scopus 로고
    • Nuclear receptors CAR and PXR in metabolism and elimination of drugs
    • P. Honkakoski Nuclear receptors CAR and PXR in metabolism and elimination of drugs Curr. Pharmacogenomics 1 2003 75 85
    • (2003) Curr. Pharmacogenomics , vol.1 , pp. 75-85
    • Honkakoski, P.1
  • 21
    • 0036515846 scopus 로고    scopus 로고
    • Receptor-dependent transcriptional activation of cytochrome P4503A genes: Induction mechanisms, species differences and interindividual variation in man
    • G.G. Gibson, N.J. Plant, K.E. Swales, A. Ayrton, and W. El-Sankary Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man Xenobiotica 32 2002 165 206
    • (2002) Xenobiotica , vol.32 , pp. 165-206
    • Gibson, G.G.1    Plant, N.J.2    Swales, K.E.3    Ayrton, A.4    El-Sankary, W.5
  • 23
    • 0024412071 scopus 로고
    • Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine
    • T. Aoyama, S. Yamano, D.J. Waxman, D.P. Lapenson, U.A. Meyer, V. Fischer, R. Tyndale, T. Inaba, W. Kalow, H.V. Gelboin, and F.J. Gonzalez Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine J. Biol. Chem. 264 1989 10388 10395
    • (1989) J. Biol. Chem. , vol.264 , pp. 10388-10395
    • Aoyama, T.1    Yamano, S.2    Waxman, D.J.3    Lapenson, D.P.4    Meyer, U.A.5    Fischer, V.6    Tyndale, R.7    Inaba, T.8    Kalow, W.9    Gelboin, H.V.10    Gonzalez, F.J.11
  • 24
    • 0034736577 scopus 로고    scopus 로고
    • The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons
    • C. Finta, and P.G. Zaphiropoulos The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons Gene 260 2000 13 23
    • (2000) Gene , vol.260 , pp. 13-23
    • Finta, C.1    Zaphiropoulos, P.G.2
  • 27
    • 0036401287 scopus 로고    scopus 로고
    • Expression and regulation of xenobiotic-metabolizing cytochrome P450 (CYP) enzymes in human lung
    • J. Hukkanen, O. Pelkonen, J. Hakkola, and H. Raunio Expression and regulation of xenobiotic-metabolizing cytochrome P450 (CYP) enzymes in human lung Crit. Rev. Toxicol. 32 2002 391 411
    • (2002) Crit. Rev. Toxicol. , vol.32 , pp. 391-411
    • Hukkanen, J.1    Pelkonen, O.2    Hakkola, J.3    Raunio, H.4
  • 28
    • 0037478407 scopus 로고    scopus 로고
    • Human extrahepatic cytochromes P450: Function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts
    • X. Ding, and L.S. Kaminsky Human extrahepatic cytochromes P450: function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts Annu. Rev. Pharmacol. Toxicol. 43 2003 149 173
    • (2003) Annu. Rev. Pharmacol. Toxicol. , vol.43 , pp. 149-173
    • Ding, X.1    Kaminsky, L.S.2
  • 29
    • 0025275855 scopus 로고
    • Carcinogen metabolism in cultured human tissues and cells
    • H. Autrup Carcinogen metabolism in cultured human tissues and cells Carcinogenesis 11 1990 707 712
    • (1990) Carcinogenesis , vol.11 , pp. 707-712
    • Autrup, H.1
  • 30
    • 0028905428 scopus 로고
    • Role of the lung in accumulation and metabolism of xenobiotic compounds - Implications for chemically induced toxicity
    • H. Foth Role of the lung in accumulation and metabolism of xenobiotic compounds - implications for chemically induced toxicity Crit. Rev. Toxicol. 26 1995 165 205
    • (1995) Crit. Rev. Toxicol. , vol.26 , pp. 165-205
    • Foth, H.1
  • 31
    • 0028985788 scopus 로고
    • Immunohistochemical localization of cytochrome P450 3A in human pulmonary carcinomas and normal bronchial tissue
    • K.T. Kivisto, P. Fritz, A. Linder, G. Friedel, P. Beaune, and H.K. Kroemer Immunohistochemical localization of cytochrome P450 3A in human pulmonary carcinomas and normal bronchial tissue Histochem. Cell Biol. 103 1995 25 29
    • (1995) Histochem. Cell Biol. , vol.103 , pp. 25-29
    • Kivisto, K.T.1    Fritz, P.2    Linder, A.3    Friedel, G.4    Beaune, P.5    Kroemer, H.K.6
  • 34
    • 0032077398 scopus 로고    scopus 로고
    • Characterisation of xenobiotic-metabolising enzyme expression in human bronchial mucosa and peripheral lung tissues
    • K. Mace, E.D. Bowman, P. Vautravers, P.G. Shields, C.C. Harris, and A.M. Pfeifer Characterisation of xenobiotic-metabolising enzyme expression in human bronchial mucosa and peripheral lung tissues Eur. J. Cancer 34 1998 914 920
    • (1998) Eur. J. Cancer , vol.34 , pp. 914-920
    • MacE, K.1    Bowman, E.D.2    Vautravers, P.3    Shields, P.G.4    Harris, C.C.5    Pfeifer, A.M.6
  • 36
    • 0030059885 scopus 로고    scopus 로고
    • Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells
    • J.D. Schuetz, E.G. Schuetz, J.V. Thottassery, P.S. Guzelian, S. Strom, and D. Sun Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells Mol. Pharmacol. 49 1996 63 72
    • (1996) Mol. Pharmacol. , vol.49 , pp. 63-72
    • Schuetz, J.D.1    Schuetz, E.G.2    Thottassery, J.V.3    Guzelian, P.S.4    Strom, S.5    Sun, D.6
  • 37
    • 0037450436 scopus 로고    scopus 로고
    • The expression of CYP2B6, CYP2C9 and CYP3A4 genes: A tangle of networks of nuclear and steroid receptors
    • J.M. Pascussi, S. Gerbal-Chaloin, L. Drocourt, P. Maurel, and M.J. Vilarem The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors Biochim. Biophys. Acta 1619 2003 243 253
    • (2003) Biochim. Biophys. Acta , vol.1619 , pp. 243-253
    • Pascussi, J.M.1    Gerbal-Chaloin, S.2    Drocourt, L.3    Maurel, P.4    Vilarem, M.J.5
  • 38
    • 12444307086 scopus 로고    scopus 로고
    • Expression of cytochromes P450 3A in mouse lung: Effects of dexamethasone and pregnenolone 16alpha-carbonitrile
    • M. Haag, A. Fautrel, A. Guillouzo, N. Frossard, and F. Pons Expression of cytochromes P450 3A in mouse lung: effects of dexamethasone and pregnenolone 16alpha-carbonitrile Arch. Toxicol. 77 2003 145 149
    • (2003) Arch. Toxicol. , vol.77 , pp. 145-149
    • Haag, M.1    Fautrel, A.2    Guillouzo, A.3    Frossard, N.4    Pons, F.5
  • 40
    • 0032565569 scopus 로고    scopus 로고
    • Activation of procarcinogens by human cytochrome P450 enzymes
    • F.P. Guengerich, and T. Shimada Activation of procarcinogens by human cytochrome P450 enzymes Mutat. Res. 400 1998 201 213
    • (1998) Mutat. Res. , vol.400 , pp. 201-213
    • Guengerich, F.P.1    Shimada, T.2
  • 42
    • 0030694259 scopus 로고    scopus 로고
    • Detection of mRNA encoding xenobiotic-metabolizing cytochrome P450s in human bronchoalveolar macrophages and peripheral blood lymphocytes
    • J. Hukkanen, J. Hakkola, S. Anttila, R. Piipari, A. Karjalainen, O. Pelkonen, and H. Raunio Detection of mRNA encoding xenobiotic-metabolizing cytochrome P450s in human bronchoalveolar macrophages and peripheral blood lymphocytes Mol. Carcinog. 20 1997 224 230
    • (1997) Mol. Carcinog. , vol.20 , pp. 224-230
    • Hukkanen, J.1    Hakkola, J.2    Anttila, S.3    Piipari, R.4    Karjalainen, A.5    Pelkonen, O.6    Raunio, H.7
  • 44
    • 0347927399 scopus 로고    scopus 로고
    • Glutathione S-transferases and aromatic DNA adducts in smokers' bronchoalveolar macrophages
    • R. Piipari, T. Nurminen, K. Savela, A. Hirvonen, T. Mantyla, and S. Anttila Glutathione S-transferases and aromatic DNA adducts in smokers' bronchoalveolar macrophages Lung Cancer 39 2003 265 272
    • (2003) Lung Cancer , vol.39 , pp. 265-272
    • Piipari, R.1    Nurminen, T.2    Savela, K.3    Hirvonen, A.4    Mantyla, T.5    Anttila, S.6
  • 45
    • 0033178677 scopus 로고    scopus 로고
    • Rat pregnane X receptor: Molecular cloning, tissue distribution, and xenobiotic regulation
    • H. Zhang, E. LeCulyse, L. Liu, M. Hu, L. Matoney, W. Zhu, and B. Yan Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation Arch. Biochem. Biophys. 368 1999 14 22
    • (1999) Arch. Biochem. Biophys. , vol.368 , pp. 14-22
    • Zhang, H.1    Leculyse, E.2    Liu, L.3    Hu, M.4    Matoney, L.5    Zhu, W.6    Yan, B.7
  • 48
    • 0030042979 scopus 로고    scopus 로고
    • Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes
    • T. Drewes, S. Senkel, B. Holewa, and G.U. Ryffel Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes Mol. Cell. Biol. 16 1996 925 931
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 925-931
    • Drewes, T.1    Senkel, S.2    Holewa, B.3    Ryffel, G.U.4
  • 51
    • 0034112122 scopus 로고    scopus 로고
    • CYP2B1 is regulated by C/EBP alpha and C/EBP delta in lung epithelial cells
    • T.N. Cassel, J.A. Gustafsson, and M. Nord CYP2B1 is regulated by C/EBP alpha and C/EBP delta in lung epithelial cells Mol. Cell. Biol. Res. Commun. 3 2000 42 47
    • (2000) Mol. Cell. Biol. Res. Commun. , vol.3 , pp. 42-47
    • Cassel, T.N.1    Gustafsson, J.A.2    Nord, M.3
  • 52
    • 0037844868 scopus 로고    scopus 로고
    • Characterization of the human lung CYP2F1 gene and identification of a novel lung-specific binding motif
    • B.A. Carr, J. Wan, R.N. Hines, and G.S. Yost Characterization of the human lung CYP2F1 gene and identification of a novel lung-specific binding motif J. Biol. Chem. 278 2003 15473 15483
    • (2003) J. Biol. Chem. , vol.278 , pp. 15473-15483
    • Carr, B.A.1    Wan, J.2    Hines, R.N.3    Yost, G.S.4
  • 53
    • 0036210930 scopus 로고    scopus 로고
    • Heterogeneous nuclear ribonucleoprotein A1 and regulation of the xenobiotic-inducible gene Cyp2a5
    • F. Raffalli-Mathieu, T. Glisovic, Y. Ben-David, and M.A. Lang Heterogeneous nuclear ribonucleoprotein A1 and regulation of the xenobiotic-inducible gene Cyp2a5 Mol. Pharmacol. 61 2002 795 799
    • (2002) Mol. Pharmacol. , vol.61 , pp. 795-799
    • Raffalli-Mathieu, F.1    Glisovic, T.2    Ben-David, Y.3    Lang, M.A.4
  • 55
    • 0033554042 scopus 로고    scopus 로고
    • Human prostate CYP3A5: Identification of a unique 5′-untranslated sequence and characterization of purified recombinant protein
    • Y. Yamakoshi, T. Kishimoto, K. Sugimura, and H. Kawashima Human prostate CYP3A5: identification of a unique 5′-untranslated sequence and characterization of purified recombinant protein Biochem. Biophys. Res. Commun. 260 1999 676 681
    • (1999) Biochem. Biophys. Res. Commun. , vol.260 , pp. 676-681
    • Yamakoshi, Y.1    Kishimoto, T.2    Sugimura, K.3    Kawashima, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.