C-Terminal Src Kinase Controls Acute Inflammation and Granulocyte Adhesion

Immunity

Volumn 20, Issue 2, 2004, Pages 181-191

  Thomas, Richard M ^a   Schmedt, Christian ^c   Novelli, Marco ^b   Choi, B Ken ^a   Skok, Jane ^a   Tarakhovsky, Alexander ^c   Roes, Jürgen ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b Rockefeller Building ^*  (United Kingdom)

^c ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRIN; LIGAND; LIPOPOLYSACCHARIDE; PHOSPHOTRANSFERASE; PROTEIN DERIVATIVE; PROTEIN SAM68;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL ADHESION; CELL MATURATION; CELL MIGRATION; CELL PROTECTION; CELL STIMULATION; CONTROLLED STUDY; DEGRANULATION; DISEASE COURSE; ENZYME ACTIVATION; ENZYME DEFICIENCY; GENE LOCUS; GRANULOCYTE; HYPERSENSITIVITY; IN VITRO STUDY; INFLAMMATION; LUNG; MICROBIOLOGY; MOUSE; MUTAGENESIS; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SKIN;

EID: 1342329483     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(04)00023-8     Document Type: Article

References (48)

1. Bainton D.F., Miller L.J., Kishimoto T.K., Springer T.A. Leukocyte adhesion receptors are stored in peroxidase-negative granules of human neutrophils. J. Exp. Med. 166:1987;1641-1653.
2. Bar-Sagi D., Hall A. Ras and Rho GTPases. a family reunion Cell. 103:2000;227-238.
3. Bergman M., Mustelin T., Oetken C., Partanen J., Flint N.A., Amrein K.E., Autero M., Burn P., Alitalo K. The human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activity. EMBO J. 11:1992;2919-2924.
4. Bergman M., Joukov V., Virtanen I., Alitalo K. Overexpressed Csk tyrosine kinase is localized in focal adhesions, causes reorganization of alpha v beta 5 integrin, and interferes with HeLa cell spreading. Mol. Cell. Biol. 15:1995;711-722.
5. Berton G., Lowell C.A. Integrin signalling in neutrophils and macrophages. Cell. Signal. 11:1999;621-635.
6. Borregaard N., Cowland J.B. Granules of the human neutrophilic polymorphonuclear leukocyte. Blood. 89:1997;3503-3521.
7. Burridge K., Turner C.E., Romer L.H. Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix. a role in cytoskeletal assembly J. Cell Biol. 119:1992;893-903.
8. Church G.M., Gilbert W. Genomic sequencing. Proc. Natl. Acad. Sci. USA. 81:1984;1991-1995.
9. Cloutier J.F., Veillette A. Cooperative inhibition of T-cell antigen receptor signaling by a complex between a kinase and a phosphatase. J. Exp. Med. 189:1999;111-121.
10. Crowley M.T., Costello P.S., Fitzer-Attas C.J., Turner M., Meng F., Lowell C., Tybulewicz V.L., DeFranco A.L. A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages. J. Exp. Med. 186:1997;1027-1039.
11. Ernst M., Inglese M., Scholz G.M., Harder K.W., Clay F.J., Bozinovski S., Waring P., Darwiche R., Kay T., Sly P.et al. Constitutive activation of the SRC family kinase Hck results in spontaneous pulmonary inflammation and an enhanced innate immune response. J. Exp. Med. 196:2002;589-604.
12. Giancotti F.G., Ruoslahti E. Integrin signaling. Science. 285:1999;1028-1032.
13. Gumienny T.L., Brugnera E., Tosello-Trampont A.C., Kinchen J.M., Haney L.B., Nishiwaki K., Walk S.F., Nemergut M.E., Macara I.G., Francis R.et al. CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration. Cell. 107:2001;27-41.
14. Hogg N., Henderson R., Leitinger B., McDowall A., Porter J., Stanley P. Mechanisms contributing to the activity of integrins on leukocytes. Immunol. Rev. 186:2002;164-171.
15. Imamoto A., Soriano P. Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice. Cell. 73:1993;1117-1124.
16. Johnson M.L., Grimwood R.E. Leukocyte colony-stimulating factors. A review of associated neutrophilic dermatoses and vasculitides. Arch. Dermatol. 130:1994;77-81.
17. Klemke R.L., Leng J., Molander R., Brooks P.C., Vuori K., Cheresh D.A. CAS/Crk coupling serves as a "molecular switch" for induction of cell migration. J. Cell Biol. 140:1998;961-972.
18. Kohara Y., Tanabe K., Matsuoka K., Kanda N., Matsuda H., Karasuyama H., Yonekawa H. A major determinant quantitative-trait locus responsible for atopic dermatitis-like skin lesions in NC/Nga mice is located on Chromosome 9. Immunogenetics. 53:2001;15-21.
19. Ley K. Integration of inflammatory signals by rolling neutrophils. Immunol. Rev. 186:2002;8-18.
20. Lowell C.A., Berton G. Resistance to endotoxic shock and reduced neutrophil migration in mice deficient for the Src-family kinases Hck and Fgr. Proc. Natl. Acad. Sci. USA. 95:1998;7580-7584.
21. Lowell C.A., Berton G. Integrin signal transduction in myeloid leukocytes. J. Leukoc. Biol. 65:1999;313-320.
22. Lowell C.A., Fumagalli L., Berton G. Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions. J. Cell Biol. 133:1996;895-910.
23. Metcalf D., Lindeman G.J., Nicola N.A. Analysis of hematopoiesis in max 41 transgenic mice that exhibit sustained elevations of blood granulocytes and monocytes. Blood. 85:1995;2364-2370.
24. Mocsai A., Ligeti E., Lowell C.A., Berton G. Adhesion-dependent degranulation of neutrophils requires the Src family kinases Fgr and Hck. J. Immunol. 162:1999;1120-1126.
25. Mocsai A., Jakus Z., Vantus T., Berton G., Lowell C.A., Ligeti E. Kinase pathways in chemoattractant-induced degranulation of neutrophils. the role of p38 mitogen-activated protein kinase activated by Src family kinases J. Immunol. 164:2000;4321-4331.
26. Mocsai A., Zhou M., Meng F., Tybulewicz V.L., Lowell C.A. Syk is required for integrin signaling in neutrophils. Immunity. 16:2002;547-558.
27. Nada S., Okada M., MacAuley A., Cooper J.A., Nakagawa H. Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src. Nature. 351:1991;69-72.
28. Nada S., Yagi T., Takeda H., Tokunaga T., Nakagawa H., Ikawa Y., Okada M., Aizawa S. Constitutive activation of Src family kinases in mouse embryos that lack Csk. Cell. 73:1993;1125-1135.
29. Nada S., Okada M., Aizawa S., Nakagawa H. Identification of major tyrosine-phosphorylated proteins in Csk-deficient cells. Oncogene. 9:1994;3571-3578.
30. Nathan C., Srimal S., Farber C., Sanchez E., Kabbash L., Asch A., Gailit J., Wright S.D. Cytokine-induced respiratory burst of human neutrophils. dependence on extracellular matrix proteins and CD11/CD18 integrins J. Cell Biol. 109:1989;1341-1349.
31. Obergfell A., Eto K., Mocsai A., Buensuceso C., Moores S.L., Brugge J.S., Lowell C.A., Shattil S.J. Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton. J. Cell Biol. 157:2002;265-275.
32. Rajewsky K., Gu H., Kühn R., Betz U.A., Müller W., Roes J., Schwenk F. Conditional gene targeting. J. Clin. Invest. 98:1996;600-603.
33. Reeves E.P., Lu H., Jacobs H.L., Messina C.G., Bolsover S., Gabella G., Potma E.O., Warley A., Roes J., Segal A.W. Killing activity of neutrophils is mediated through activation of proteases by K+ flux. Nature. 416:2002;291-297.
34. Savill J., Dransfield I., Gregory C., Haslett C. A blast from the past. clearance of apoptotic cells regulates immune responses Nat. Rev. Immunol. 2:2002;965-975.
35. Schaller M.D., Parsons J.T. pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high- affinity binding site for Crk. Mol. Cell. Biol. 15:1995;2635-2645.
36. Schmedt C., Saijo K., Niidome T., Kühn R., Aizawa S., Tarakhovsky A. Csk controls antigen receptor-mediated development and selection of T-lineage cells. Nature. 394:1998;901-904.
37. Schoenwaelder S.M., Burridge K. Bidirectional signaling between the cytoskeleton and integrins. Curr. Opin. Cell Biol. 11:1999;274-286.
38. Shultz L.D. Hematopoiesis and models of immunodeficiency. Semin. Immunol. 3:1991;397-408.
39. Suen P.W., Ilic D., Caveggion E., Berton G., Damsky C.H., Lowell C.A. Impaired integrin-mediated signal transduction, altered cytoskeletal structure and reduced motility in Hck/Fgr deficient macrophages. J. Cell Sci. 112:1999;4067-4078.
40. Tkalcevic J., Novelli M., Phylactides M., Iredale J.P., Segal A.W., Roes J. Impaired immunity and enhanced resistance to endotoxin in the absence of neutrophil elastase and cathepsin G. Immunity. 12:2000;201-210.
41. Torgersen K.M., Vang T., Abrahamsen H., Yaqub S., Horejsi V., Schraven B., Rolstad B., Mustelin T., Tasken K. Release from tonic inhibition of T cell activation through transient displacement of C-terminal Src kinase (Csk) from lipid rafts. J. Biol. Chem. 276:2001;29313-29318.
42. Turner C.E. Paxillin interactions. J. Cell Sci. 113:2000;4139-4140.
43. Uruno T., Liu J., Zhang P., Fan Y., Egile C., Li R., Mueller S.C., Zhan X. Activation of Arp2/3 complex-mediated actin polymerization by cortactin. Nat. Cell Biol. 3:2001;259-266.
44. Veillette A., Latour S., Davidson D. Negative regulation of immunoreceptor signaling. Annu. Rev. Immunol. 20:2002;669-707.
45. Vestergaard C., Yoneyama H., Matsushima K. The NC/Nga mouse. a model for atopic dermatitis Mol. Med. Today. 6:2000;209-210.
46. Wang B., Lemay S., Tsai S., Veillette A. SH2 domain-mediated interaction of inhibitory protein tyrosine kinase Csk with protein tyrosine phosphatase-HSCF. Mol. Cell. Biol. 21:2001;1077-1088.
47. Weedon D. Skin Pathology. 1997;Churchill Livingstone, New York.
48. Zhou X., Li J., Kucik D.F. The microtubule cytoskeleton participates in control of beta2 integrin avidity. J. Biol. Chem. 276:2001;44762-44769.