The NC/Nga mouse: A model for atopic dermatitis

Molecular Medicine Today

Volumn 6, Issue 5, 2000, Pages 209-210

  Vestergaard, Christian ^a   Yoneyama, Hiroyuki ^b   Matsushima, Konji ^b  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; TACROLIMUS;

ARTICLE; ATOPIC DERMATITIS; CLINICAL FEATURE; CYTOKINE PRODUCTION; DISEASE MODEL; HUMAN; NONHUMAN; SKIN CELL; SPECIES DIFFERENCE; TREATMENT OUTCOME;

ANIMALIA;

EID: 0034192647     PISSN: 13574310     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-4310(00)01683-X     Document Type: Review

References (7)

1. Rudikoff D., Lebwohl M. Atopic dermatitis. Lancet. 351:1998;1715-1721.
2. Matsuda H.et al. Development of atopic dermatitis-like skin lesion with IgE hyperproduction in NC/Nga mice. Int. Immunol. 9:1997;461-466.
3. Matsumoto M.et al. IgE hyperproduction through enhanced tyrosine phosphorylation of Janus kinase 3 in NC/Nga mice, a model for human atopic dermatitis. J. Immunol. 162:1999;1056-1063.
4. Vestergaard C.et al. Overproduction of Th2-specific chemokines in NC/Nga mice exhibiting atopic dermatitis-like lesions. J. Clin. Invest. 104:1999;1097-1105.
5. Hamid Q.et al. Differential in situ cytokine gene expression in acute versus chronic atopic dermatitis. J. Clin. Invest. 94:1994;870-876.
6. Campbell J.J.et al. The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells. Nature. 400:1999;776-780.
7. Hiroi J.et al. Effect of tacrolimus hydrate (FK506) ointment on spontaneous dermatitis in NC/Nga mice. Jpn. J. Pharmacol. 76:1998;175-183.