A major determinant quantitative-trait locus responsible for atopic dermatitis-like skin lesions in NC/Nga mice is located on Chromosome 9

Immunogenetics

Volumn 53, Issue 1, 2001, Pages 15-21

  Kohara, Y ^a   Tanabe, K ^a   Matsuoka, K ^a   Kanda, N ^a   Matsuda, H ^a   Karasuyama, H ^a   Yonekawa, H ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

Atopy; Linkage disequilibrium; Microsatellite; Model mouse; RH panel

Indexed keywords

MICROSATELLITE DNA;

ALLERGIC REACTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATOPIC DERMATITIS; ATOPY; CENTROMERE; CHROMOSOME 9; DISEASE MODEL; GENE LINKAGE DISEQUILIBRIUM; GENE LOCATION; GENE LOCUS; IMMUNOGLOBULIN PRODUCTION; LYMPHOCYTE FUNCTION; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROGENY; QUANTITATIVE TRAIT; SYMPTOM; T LYMPHOCYTE;

ANIMALS; CHROMOSOME MAPPING; CROSSES, GENETIC; DERMATITIS, ATOPIC; IMMUNITY, NATURAL; LINKAGE DISEQUILIBRIUM; MICE; MICROSATELLITE REPEATS; QUANTITATIVE TRAIT, HERITABLE; RADIATION HYBRID MAPPING; SKIN;

ANIMALIA; MUS; MUS MUSCULUS MOLOSSINUS; MUSCULUS; RODENTIA;

EID: 0035092589     PISSN: 00937711     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002510000286     Document Type: Article

References (27)

1. Impairment of skin barrier function in NC/NgaTnd mice as a possible murine model for atopic dermatitis
2. The role of IL-18 in innate immunity
3. The human p50csk tyrosine kinase phosphorylates p561ck at Tyr-505 and down regulates its catalytic activity
4. Linkage between immunoglobulin E responses underlying asthma and rhinitis and chromosome 11q
5. Maternal inheritance of atopic IgE responsiveness on chromosome 11q
6. Origins and chracteristics of inbred strains of mice
7. A role for Th1 and Th2 cells in the immunopathogenesis of atopic dermatitis
8. Atopic dermatitis
9. Immunobiochemical aspects of atopic dermatitis
10. Diagnostic features of atopic dermatitis
11. The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor
12. A receptor for interleukin 10 is related to interferon receptors
13. The NC/Nga strain of mouse
14. Thy-1 functions as a signal transduction molecule in T lymphocytes and transfected B lymphocytes
15. Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
16. Genetic dissection of complex traits
17. Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations
18. Development of atopic dermatitis-like skin lesion with IgE hyperproduction in NC/Nga mice
19. Genetic linkage of T-cell receptor alpha/delta complex to specific IgE responses
20. Susceptibility genes for allergy and asthma
21. Identification of the components of the murine T cell antigen receptor complex
22. Linkage between severe atopy and chromosome 11q13 in Japanese families
23. Changes in the reported prevalence of childhood eczema since the 1939-45 war
24. Genetic analysis for dermatitis and IgE hyperproduction in the NC/Nga mouse
25. Overproduction of Th2-specific chemokines in NC/Nga mice exhibiting atopic dermatitis-like lesions
26. HLA-DR and HLA-DP genotypes and immunoglobulin E responses to common major allergens
27. Association of class II DNA restriction fragments with responsiveness to Ambrosia artemisiifolia (short ragweed)-pollen allergen Amb a V in ragweed-allergic patients