Retraction: Involvement of Hus1 in the chain elongation step of DNA replication after exposure to camptothecin or ionizing radiation (Nucleic Acids Research (2004) 32:2 (767-775) DOI: 10.1093/nar/gkh243);Involvement of Hus1 in the chain elongation step of DNA replication after exposure to camptothecin or ionizing radiation

Nucleic Acids Research

Volumn 32, Issue 2, 2004, Pages 767-775

  Wang, Xiang ^c   Guan, Jun ^c,d   Hu, Baocheng ^c,e   Weiss, Robert S ^a   Iliakis, George ^b   Wang, Ya ^c  

^a Department of Obstetrics Gynecology   (United States)

^b UNIVERSITY OF ESSEN MEDICAL SCHOOL   (Germany)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e BEIJING INSTITUTE OF BIOTECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN; CELL CYCLE PROTEIN; CHECKPOINT KINASE 1; CHECKPOINT PROTEIN; CYCLINE; PHOSPHOTRANSFERASE; PROTEIN RAD9; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CYCLE S PHASE; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; DNA STRAND BREAKAGE; DRUG EXPOSURE; ENZYME ACTIVATION; IONIZING RADIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RADIATION EXPOSURE; REPLICON; SENSOR;

EID: 1342327642     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkaa119     Document Type: Erratum

References (58)

1. Paulovich ,A.G. and Hartwell ,L.H. (1995) A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage. Cell, 82, 841-847.
2. Paulovich, A.G., Toczyski ,D.P. and Hartwell, L.H. (1997) When checkpoints fail. Cell, 88, 315-321.
3. Eller, M.S., Ostrom, K. and Gilchrest ,B.A. (1996) DNA damage enhances melanogenesis. Proc. Natl Acad. Sci. USA, 93, 1087-1092.
4. Zhou, B.-B.S. and Elledge, S.J. (2000) The DNA damage response: putting checkpoints in perspective. Nature, 408, 433-439.
5. Painter, R.B. and Young ,B.R. (1980) Radiosensitivity in ataxia-telangiectasia: a new explanation. Proc. Natl Acad. Sci. USA, 77, 7315-7317.
6. Xu, B., Kim, S.-T. and Kastan ,M.B. (2001) Involvement of Brca1 in S-phase and G2-phase checkpoints after ionizing irradiation. Mol. Cell. Biol., 21, 3445-3450.
7. Watanabe, I. (1974) Radiation effects on DNA chain growth in mammalian cells. Radiat. Res., 58, 541-556.
8. Painter, R.B. and Young, B.R. (1975) X-ray-induced inhibition of DNA synthesis in Chinese hamster ovary, human HeLa and mouse L cells. Radiat. Res., 64, 648-656.
9. Painter ,R.B. and Young, B.R. (1976) Formation of nascent DNA molecules during inhibition of replicon initiation in mammalian cells. Biochim. Biophys. Acta, 418, 146-153.
10. Wang, X. and Iliakis, G. (1993) Persistent inhibition of DNA synthesis after radiation exposure in four clones obtained from rat embryo fibroblasts by transfection with the oncogenes H-ras plus v-myc. Int. J. Radiat. Biol., 64, 165-168.
11. Guan, J., DiBiase, S. and Iliakis, G. (2000) The catalytic subunit DNA-dependent protein kinase (DNA-PKcs) facilitates recovery from radiation-induced inhibition of DNA replication. Nucleic Acids Res., 28, 1183-1192.
12. Heffernan, T.P., Simpson, D.A., Frank ,A.R., Heinloth ,A.N., Paules, R.S ., Cordeiro-Stone ,M. and Kaufmann, W.K. (2002) An ATR- and Chk1-dependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage. Mol. Cell. Biol., 22, 8552-8561.
13. Aravind, L., Walker ,D.R. and Koonin, E.V. (1999) Conserved domains in DNA repair proteins and evolution of repair systems. Nucleic Acids Res., 27, 1223-1242.
14. St. Onge, R.P., Udell, C.M., Casselman, R. and Davey, S. (1999) The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1. Mol. Biol. Cell, 10, 1985-1995.
15. Volkmer ,E. and Karnitz ,L.M. (1999) Human homologs of Schizosaccharomyces pombe Rad1, Hus1 and Rad9 form a DNA damage-responsive protein complex. J. Biol. Chem., 274, 567-570.
16. Rauen, M., Burtelow, M.A., Dufault, V.M. and Karnitz, L.M. (2000) The human checkpoint protein hRad17 interacts with the PCNA-like proteins hRad1, hHus1 and hRad9. J. Biol. Chem., 275, 29767-29771.
17. Caspari ,T., Dahlen, M., Kanter-Smoler ,G., Lindsay, H.D., Hofmann ,K., Papadimitriou, K., Sunnerhagen, P. and Carr ,A.M. (2000) Characterization of Schizosaccharomyces pombe Hus1: a PCNA-related protein that associates with Rad1 and Rad9. Mol. Cell. Biol., 74, 1254-1262.
18. O'Connell ,M.J., Walworth, N.C. and Carr, A.M. (2000) The G2-phase DNA-damage checkpoint. Trends Cell Biol., 10, 296-303.
19. Enoch, T., Carr, A.M. and Nurse ,P. (1992) Fission yeast genes involved in coupling mitosis to completion of DNA replication. Genes Dev., 6, 2035-2046.
20. Weiss, R.S., Enoch, T. and Leder, P. (2000) Inactivation of mouse Hus1 results in genomic instability and impaired responses to genotoxic stress. Genes Dev., 14, 1886-1898.
21. Komatsu ,K., Wharton, W., Hang, H., Wu, C., Singh ,S., Lieberman ,H.B., Pledger, W.J. and Wang, H.-G. (2000) PCNA interacts with hHus1/hRad9 in response to DNA damage and replication inhibition. Oncogene, 19, 5291-5297.
22. Weiss ,R.S., Matsuoka ,S., Elledge ,S.J. and Leder, P. (2002) Hus1 acts upstream of Chk1 in a mammalian DNA damage response pathway. Curr. Biol., 12, 73-77.
23. Weiss ,R.S., Leder ,P. and Vaziri, C. (2003) Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint. Mol. Cell. Biol., 23, 791-803.
24. Wang, H., Wang, X., Zhou, X.Y., Chen, D.J., Li, G.C., Iliakis, G. and Wang, Y. (2002) Ku affects the Ataxia and Rad 3-related/Chk1-dependent S-phase checkpoint response after camptothecin treatment. Cancer Res., 62, 2483-2487.
25. Wan ,S., Capasso ,H. and Walworth ,N.C. (1999) The topoisomerase I poison camptothecin generates a Chk1 dependent DNA damage checkpoint signal in fission yeast. Yeast, 15, 821-828.
26. Cliby, W.A., Lewis, K.A., Lilly, K.K. and Kaufmann ,S.H. (2002) S Phase and G2 arrests induced by topoisomerase I poisons are dependent on ATR kinase function. J. Biol. Chem., 277, 1599-1606.
27. Wang, J.-L., Wang, X., Wang, H., Iliakis ,G. and Wang ,Y. (2002) CHK1-regulated S-phase checkpoint response reduces camptothecin cytotoxicity. Cell Cycle, 1, 267-272.
28. Xiao, Z., Chen, Z., Gunasekera ,A.H., Sowin, T.J., Rosenberg ,S.H., Fesik ,S. and Zhang ,H. (2003) Chk1 mediates S and G2 arrest through Cdc25A degradation in response to DNA-damaging agents. J. Biol. Chem., 278, 21767-21773.
29. Zhou, X.Y., Wang, X., Hu, B., Guan ,J., Iliakis, G. and Wang, Y. (2002) An ATM-independent S phase checkpoint response involves CHK1 pathway. Cancer Res., 62, 1598-1603.
30. Wang, Y., Cheong, N. and Iliakis, G. (1993) Persistent inhibition of DNA synthesis in irradiated rat embryo fibroblasts expressing the oncogenes H-ras plus v-myc derives from inhibition of replicon initiation and is mitigated by staurosporine. Cancer Res., 53, 1213-1217.
31. Zou, L., Cortez ,D. and Elledge, S.J. (2002) Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin. Genes Dev., 16, 198-208.
32. Yazdi, P.T., Wang ,Y., Zhao ,S., Patel ,N., Lee, E.Y.-H.P. and Qin ,J. (2002) SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint. Genes Dev., 16, 571-582.
33. Zhao, H., Watkins, J.L. and Piwnica-Worms ,H. (2002) Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints. Proc. Natl Acad. Sci. USA, 99, 14795-14800.
34. Bravo, R. and Macdonald-Bravo ,H. (1987) Existence of two populations of cyclin/proliferating cell nuclear antigen during the cell cycle: association with DNA replication sites. J. Cell Biol., 105, 1549-1554.
35. Humbert, C., Santisteban, M.S., Usson, Y. and Robert-Nicoud, M. (1992) Intranuclear co-location of newly replicated DNA and PCNA by simultaneous immunofluorescent labeling and confocal microscopy in MCF-7 cells. J. Cell. Sci., 103, 97-103.
36. Waga, S. and Stillman ,B. (1998) The DNA replication fork in eukaryotic cells. Annu. Rev. Biochem., 67, 721-751.
37. Li, R., Hannon ,G.J., Beach, D. and Stillman ,B. (1996) Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage. Curr. Biol., 6, 189-199.
38. Yoshida, K., Wang, H.-G., Miki, Y. and Kufe, D. (2003) Protein kinase Cδ is responsible for constitutive and DNA damage-induced phosphorylation of Rad9. EMBO J., 22, 1431-1441.
39. Chen, M.-J., Lin ,Y.-T., Lieberman, H.B., Chen, G. and Lee, E.Y.-H.P. (2001) ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation. J. Biol. Chem., 276, 16580-16586.
40. Kim, S.-T., Xu, B. and Kastan, M.B. (2002) Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage. Genes Dev., 16, 560-570.
41. Rauen, M., Burtelow, M.A., Dufault, V.M. and Karnitz ,L.M. (2000) The human checkpoint protein hRad17 interacts with the PCNA-like protein hRad1, hHus1 and hRad9. J. Biol. Chem., 275, 29767-29771.
42. Ward, I.M. and Chen, J. (2001) Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress. J. Biol. Chem., 276, 47759-47762.
43. Houldsworth, J. and Lavin, M.F. (1980) Effect of ionizing radiation on DNA synthesis in ataxia telangiectasia cells. Nucleic Acids Res., 8, 3709-3720.
44. Falck, J., Mailand, N., Syljuasen, R.G., Bartek, J. and Lukas, J. (2001) The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature, 410, 842-847.
45. Falck ,J., Petrini, J.H.J., Williams, B.R., Lukas, J. and Bartek, J. (2002) The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways. Nature Genet., 30, 290-294.
46. Burtelow, M.A., Roos-Mattjus, P.M.K., Rauen ,M., Babendure ,J.R. and Karnitz, L.M. (2001) Reconstitution and molecular analysis of the hRad9-hHus1-hRad1 (9-1-1) DNA damage responsive checkpoint complex. J. Biol. Chem., 276, 25903-25909.
47. Dahm, K. and Hubscher, U. (2002) Colocalization of human Rad17 and PCNA in late S phase of the cell cycle upon replication block. Oncogene, 21, 7710-7719.
48. Wang, Y., Perrault, A.R. and Iliakis ,G. (1997) Down-regulation of DNA replication in extracts of camptothecin-treated cells: activation of an S-phase checkpoint? Cancer Res., 57, 1654-1659.
49. Wang, Y. and Iliakis, G. (1992) Prolonged inhibition by x-rays of DNA synthesis in cells obtained by transformation of primary rat embryo fibroblasts with oncogenes H-ras and v-myc. Cancer Res., 52, 508-514.
50. Guo, C.Y., Brautigan, D.L. and Larner, J.M. (2002) Ionizing radiation activates nuclear protein phosphatase-1 by ATM-dependent dephosphorylation. J. Biol. Chem., 277, 41756-41761.
51. Bakkenist, C.J. and Kastan, M.B. (2003) DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature, 421, 499-506.
52. Brown, E.J. and Baltimore, D. (2003) Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance. Genes Dev., 17, 615-628.
53. Roos-Mattjus, P., Vroman, B.T., Burtelow, M.A., Rauen ,M., Eapen, A.K. and Karnitz ,L.M. (2002) Genotoxin-induced Rad9-Hus1-Rad1 (9-1-1) chromatin association is an early checkpoint signaling event. J. Biol. Chem., 277, 43809-43812.
54. Bao ,S., Tibbetts, R.S., Brumbaugh ,K.M., Fang, Y., Richardson, D.A., Ali, A., Chen, S.M., Abraham, R.T. and Wang, X.F. (2001) ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses. Nature, 411, 969-974.
55. Giannattasio ,M., Sommariva, E., Vercillo, R., Lippi-Boncambi, F., Liberi, G., Foiani, M., Plevani, P. and Muzi-Falconi ,M. (2002) A dominant-negative MEC3 mutant uncovers new functions for the Rad17 complex and Tel1. Proc. Natl Acad. Sci. USA, 99, 12997-13002.
56. Giannattasio, M., Sabbioneda, S., Minuzzo ,M., Plevani ,P. and Muzi-Falconi, M. (2003) Correlation between checkpoint activation and in vivo assembly of the yeast checkpoint complex Rad17-Mec3-Ddc1. J. Biol. Chem., 278, 22303-22308.
57. Zou ,L. and Elledge, S.J. (2003) Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science, 300, 1542-1548.
58. Kai ,M. and Wang, T.S.-F. (2003) Checkpoint activation regulates mutagenic translesion synthesis. Genes Dev., 17, 64-76.