Hydrolysis of N-methyl-D-aspartate receptor-stimulated cAMP and cGMP by PDE4 and PDE2 phosphodiesterases in primary neuronal cultures of rat cerebral cortex and hippocampus

Journal of Pharmacology and Experimental Therapeutics

Volumn 302, Issue 1, 2002, Pages 249-256

  Suvarna, Neesha U ^a   O'Donnell, James M ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (2 CYCLOPENTYL 2 HYDROXY 2 PHENYLETHOXY)QUINUCLIDINE; ADENOSINE DEAMINASE INHIBITOR; CYCLIC GMP; CYCLIC NUCLEOTIDE; DIZOCILPINE MALEATE; GLUTAMATE RECEPTOR; ISOBUTYLMETHYLXANTHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHOSPHODIESTERASE I; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE IV; PROTEIN KINASE (CALCIUM,CALMODULIN); ROLIPRAM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; CALCIUM TRANSPORT; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DRUG EFFECT; GENETIC TRANSCRIPTION; HIPPOCAMPUS; HYDROLYSIS; LIGAND BINDING; LONG TERM POTENTIATION; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ADENINE; ADENOSINE; ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; CYCLIC AMP; CYCLIC GMP; DIZOCILPINE MALEATE; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; GUANYLATE CYCLASE; HIPPOCAMPUS; N-METHYLASPARTATE; NEURONS; NITRIC OXIDE DONORS; NITRIC OXIDE SYNTHASE; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; ROLIPRAM;

EID: 0036088736     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.302.1.249     Document Type: Article

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