Overexpression of XIAP inhibits apoptotic cell death in an oligodendroglial cell line

Cellular and Molecular Neurobiology

Volumn 24, Issue 6, 2004, Pages 853-863

  Jin, Ying ^a   McEwen, Melanie L ^a   Ghandour, M Said ^b   Springer, Joe E ^a,c  

^a UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

^b CNRS   (France)

^c Cardinal Hill Rehabilitation Hospital   (United States)

Author keywords

Apoptosis; Demyelination; IAPs, spinal cord injury, multiple sclerosis

Indexed keywords

CASPASE 3; MYC PROTEIN; STAUROSPORINE; X LINKED INHIBITOR OF APOPTOSIS;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL FUNCTION; CELL LINE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC TRANSFECTION; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; STAINING; STATISTICAL SIGNIFICANCE;

APOPTOSIS; CELL DEATH; CELL LINE, TRANSFORMED; GENE EXPRESSION REGULATION; HUMANS; OLIGODENDROGLIA; PROTEINS; TRANSFECTION; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

ANIMALIA; INTRACISTERNAL A-PARTICLES;

EID: 12944303668     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10571-004-6924-9     Document Type: Article

References (39)

1. Barzilai, A., Zilkha-Falb, R., Daily, D., Stern, N., Offen, D., Ziv, I., Melamed, E., and Shirvan, A. (2000). The molecular mechanism of dopamine-induced apoptosis: Identification and characterization of genes that mediate dopamine toxicity. J Neural Transm Suppl. 59-76.
2. Beattie, M. S., Farooqui, A. A., and Bresnahan, J. C. (2000). Review of current evidence for apoptosis after spinal cord injury. J. Neurotrauma 17:915-925.
3. Beattie, M. S., Hermann, G. E., Rogers, R. C., and Bresnahan, J. C. (2002). Cell death in models of spinal cord injury. Prog. Brain. Res. 137:37-47.
4. Cao, G., Pei, W., Lan, J., Stetler, R. A., Luo, Y., Nagayama, T., Graham, S. H., Yin, X. M., Simon, R. P., and Chen, J. (2001). Caspase-activated DNase/DNA fragmentation factor 40 mediates apoptotic DNA fragmentation in transient cerebral ischemia and in neuronal cultures. J. Neurosci. 21:4678-4690.
5. Chen, J., Nagayama, T., Jin, K., Stetler, R. A., Zhu, R. L., Graham, S. H., and Simon, R. P. (1998). Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia. J. Neurosci. 18:4914-4928.
6. Citron, B. A., Arnold, P. M., Sebastian, C., Qin, F., Malladi, S., Ameenuddin, S., Landis, M. E., and Festoff. B. W. (2000). Rapid upregulation of caspase-3 in rat spinal cord after injury: mRNA, protein, and cellular localization correlates with apoptotic cell death. Exp. Neurol. 166:213-226.
7. Clark, R. S., Kochanek, P. M., Watkins, S. C., Chen, M., Dixon, C. E., Seidberg, N. A., Melick, J., Loeffert, J. E., Nathaniel, P. D., Jin, K. L., and Graham, S. H. (2000). Caspase-3 mediated neuronal death after traumatic brain injury in rats. J. Neurochem. 74:740-753.
8. Conti, A. C., Raghupathi, R., Trojanowski, J. Q., and McIntosh, T. K. (1998). Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period. J. Neurosci. 18:5663-5672.
9. Crowe, M. J., Bresnahan, J. C., Shuman, S. L., Masters, J. N., and Beattie, M. S. (1997). Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys. Nat. Med. 3:73-76.
10. Deveraux, Q. L., Roy, N., Stennicke, H. R., Van Arsdale, T., Zhou, Q., Srinivasula, S. M., Alnemri, E. S., Salvesen, G. S., and Reed, J. C. (1998). IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases. Embo. J. 17:2215-2223.
11. Du, C., Fang, M., Li, Y., Li, L., and Wang, X. (2000). Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 102:33-42.
12. Duckett, C. S., Li, F., Wang, Y., Tomaselli, K. J., Thompson, C. B., and Armstrong, R. C. (1998). Human IAP-like protein regulates programmed cell death downstream of Bcl-xL and cytochrome c. Mol. Cell. Biol. 18:608-615.
13. Eberhardt, O., Coelln, R. V., Kugler, S., Lindenau, J., Rathke-Hartlieb, S., Gerhardt, E., Haid, S., Isenmann, S., Gravel, C., Srinivasan, A., Bahr, M., Weller, M., Dichgans, J., and Schulz, J. B. (2000). Protection by synergistic effects of adenovirus-mediated X-chromosome-linked inhibitor of apoptosis and glial cell line-derived neurotrophic factor gene transfer in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. J. Neurosci. 20:9126-9134.
14. Eldadah, B. A., and Faden, A. I. (2000). Caspase pathways, neuronal apoptosis, and CNS injury. J. Neurotrauma 17:811-829.
15. Emery, E., Aldana, P., Bunge, M. B., Puckett, W., Srinivasan, A., Keane, R. W., Bethea, J., and Levi, A. D. (1998). Apoptosis after traumatic human spinal cord injury. J. Neurosurg. 89:911-920.
16. Feutz, A. C., Pham-Dinh, D., Allinquant, B., Miehe, M., and Ghandour, M. S. (2001). An immortalized jimpy oligodendrocyte cell line: Defects in cell cycle and cAMP pathway. Glia 34:241-252.
17. Fujimura, M., Morita-Fujimura, Y., Kawase, M., Copin, J. C., Calagui, B., Epstein, C. J., and Chan, P. H. (1999). Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome C and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice. J. Neurosci. 19:3414-3422.
18. Hay, B. A. (2000). Understanding IAP function and regulation: A view from Drosophila. Cell Death Differ. 7:1045-1056.
19. Holcik, M., Gibson, H., and Korneluk, R. G. (2001). XIAP: Apoptotic brake and promising therapeutic target. Apoptosis 6:253-261.
20. Jones, D. C., Gunasekar, P. G., Borowitz, J. L., and Isom, G. E. (2000). Dopamine-induced apoptosis is mediated by oxidative stress and is enhanced by cyanide in differentiated PC12 cells. J. Neurochem. 74:2296-2304.
21. Keane, R. W. Kraydieh, S., Lotocki, G., Alonso, O. F., Aldana, P., and Dietrich, W. D. (2001a). Apoptotic and antiapoptotic mechanisms after traumatic brain injury. J. Cereb. Blood Flow Metab. 21:1189-1198.
22. Keane, R. W., Kraydieh, S., Lotocki, G., Bethea, J. R., Krajewski, S., Reed, J. C., and Dietrich, W. D. (2001b). Apoptotic and anti-apoptotic mechanisms following spinal cord injury. J. Neuropathol Exp. Neurol. 60:422-429.
23. Korhonen, L., Belluardo, N., and Lindhohn, D. (2001). Regulation of X-chromosome-linked inhibitor of apoptosis protein in kainic acid-induced neuronal death in the rat hippocampus. Mol. Cell Neurosci. 17:364-372.
24. Kugler, S., Straten, G., Kreppel, F., Isenmann, S., Liston, P., and Bahr, M. (2000). The X-linked inhibitor of apoptosis (XIAP) prevents cell death in axotomized CNS neurons in vivo. Cell Death Differ. 7:815-824.
25. Lee, H. J., Kim, S. H., Kim, K. W., Um, J. H., Lee, H. W. Chung, B. S., and Kang, C. D. (2001). Antiapoptotic role of NF-kappaB in the auto-oxidized dopamine-induced apoptosis of PC12 cells. J. Neurochem. 76:602-609.
26. Liston, P., Roy, N., Tamai, K., Lefebvre, C., Baird, S., Cherton-Horvat, G., Farahani, R., McLean, M., Ikeda, J. E., MacKenzie, A., and Korneluk, R. G. (1996). Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes. Nature 379:349-353.
27. Liu, X. Z., Xu, X. M., Hu, R., Du, C., Zhang, S. X., McDonald, J. W., Dong, H. X., Wu, Y. J., Fan, G. S., Jacquin, M. F., Hsu, C. Y., and Choi, D. W. (1997). Neuronal and glial apoptosis after traumatic spinal cord injury. J. Neurosci. 17:5395-5406.
28. Namura, S., Zhu, J., Fink, K., Endres, M., Srinivasan, A., Tomaselli, K. J., Yuan, J., and Moskowitz, M. A. (1998). Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia. J. Neurosci. 18:3659-3668.
29. Newcomb, J. K., Zhao, X., Pike, B. R., and Hayes, R. L. (1999). Temporal profile of apoptotic-like changes in neurons and astrocy tes following controlled cortical impact injury in the rat. Exp. Neurol. 158:76-88.
30. Pike, B. R., Zhao, X., Newcomb, J. K., Wang, K. K., Posmantur, R. M., and Hayes, R. L. (1998). Temporal relationships between de novo protein synthesis, calpain and caspase 3-like protease activation, and DNA fragmentation during apoptosis in septo-hippocampal cultures. J. Neurosci. Res. 52:505-520.
31. Rink, A., Fung, K. M., Trojanowski, J. Q., Lee, V. M., Neugebauer, E., and McIntosh, T. K. (1995). Evidence of apoptotic cell death after experimental traumatic brain injury in the rat. Am. J. Pathol. 147:1575-1583.
32. Salvesen, G. S., and Duckett, C. S. (2002). IAP proteins: Blocking the road to death's door. Nat. Rev. Mol. Cell Biol. 3:401-410.
33. Simons, M., Beinroth, S., Gleichmann, M., Liston, P., Korneluk, R. G., MacKenzie, A. E., Bahr, M., Klockgether, T., Robertson, G. S., Weller, M., and Schulz, J. B. (1999). Adenovirus-mediated gene transfer of inhibitors of apoptosis protein delays apoptosis in cerebellar granule neurons. J. Neurochem. 72:292-301.
34. Springer, J., Azbill, R., and Knapp, P. (1999). Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury. Nature Medicine 5:943-946.
35. Springer, J., Azbill, R., Nottingham, S., and Kennedy, S. (2000). Calcineurin-mediated BAD dephosphorylation activates the caspase-3 apoptotic cascade in traumatic spinal cord injury. J. Neurosci. 20:7246-7251.
36. Springer, J. E., Nottingham, S. A., McEwen, M. L., Azbill, R. D., and Jin, Y. (2001). Caspase-3 apoptotic signaling following injury to the central nervous system. Clin. Chem. Lab. Med. 39:299-307.
37. Stokes, A. H., Lewis, D. Y., Lash, L. H., Jerome, W. G. 3rd, Grant, K. W., Aschner, M., and Vrana, K. E. (2000). Dopamine toxicity in neuroblastoma cells: role of glutathione depletion by L-BSO and apoptosis. Brain. Res. 858:1-8.
38. Verhagen, A. M., Ekert, P. G., Pakusch, M., Silke, J., Connolly, L. M., Reid, G. E., Moritz, R. L., Simpson, R. J., and Vaux, D. L. (2000). Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell 102:43-53.
39. Xu, D., Bureau, Y., McIntyre, D. C., Nicholson, D. W., Liston, P., Zhu, Y., Fong, W. G., Crocker, S. J., Korneluk, R. G., and Robertson, G. S. (1999). Attenuation of ischemia-induced cellular and behavioral deficits by X chromosome-linked inhibitor of apoptosis protein overexpression in the rat hippocampus. J. Neurosci. 19:5026-5033.