-
1
-
-
0037082324
-
Target validation of G-protein coupled receptors
-
Wise A, Gearing K, Rees S. Target validation of G-protein coupled receptors. Drug Discov Today 2002;7:235-246.
-
(2002)
Drug Discov Today
, vol.7
, pp. 235-246
-
-
Wise, A.1
Gearing, K.2
Rees, S.3
-
2
-
-
0037024360
-
Identification of G protein-coupled receptor genes from the human genome sequence
-
Takeda S, Kadowaki S, Haga T, Takaesu H, Mitaku S. Identification of G protein-coupled receptor genes from the human genome sequence. FEBS Lett 2002;520:97-101.
-
(2002)
FEBS Lett
, vol.520
, pp. 97-101
-
-
Takeda, S.1
Kadowaki, S.2
Haga, T.3
Takaesu, H.4
Mitaku, S.5
-
3
-
-
0037446894
-
The G protein-coupled receptor repertoires of human and mouse
-
Vassilatis DK, Hohmann JG, Zeng H, Li F, Ranchalis JE, Mortrud MT, Brown A, Rodriguez SS, Weller JR, Wright AC, Bergmann JE, Gaitanaris GA. The G protein-coupled receptor repertoires of human and mouse. Proc Natl Acad Sci USA 2003;100:4903-4908.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 4903-4908
-
-
Vassilatis, D.K.1
Hohmann, J.G.2
Zeng, H.3
Li, F.4
Ranchalis, J.E.5
Mortrud, M.T.6
Brown, A.7
Rodriguez, S.S.8
Weller, J.R.9
Wright, A.C.10
Bergmann, J.E.11
Gaitanaris, G.A.12
-
4
-
-
0035318509
-
Oligomerization of G-protein-coupled transmitter receptors
-
Bouvier M. Oligomerization of G-protein-coupled transmitter receptors. Nat Rev Neurosci 2001;2:274-286.
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 274-286
-
-
Bouvier, M.1
-
5
-
-
0034937698
-
G protein coupled receptor dimerization: Implications in modulating receptor function
-
Gomes I, Jordan BA, Gupta A, Rios C, Trapaidze N, Devi LA. G protein coupled receptor dimerization: implications in modulating receptor function. J Mol Med 2001;79:226-242.
-
(2001)
J Mol Med
, vol.79
, pp. 226-242
-
-
Gomes, I.1
Jordan, B.A.2
Gupta, A.3
Rios, C.4
Trapaidze, N.5
Devi, L.A.6
-
6
-
-
0035726693
-
G-protein-coupled receptor dimerization: Modulation of receptor function
-
Rios CD, Jordan BA, Gomes I, Devi LA. G-protein-coupled receptor dimerization: modulation of receptor function. Pharmacol Ther 2001;92:71-87.
-
(2001)
Pharmacol Ther
, vol.92
, pp. 71-87
-
-
Rios, C.D.1
Jordan, B.A.2
Gomes, I.3
Devi, L.A.4
-
7
-
-
0036174608
-
Dimerization:an emerging concept for G protein-coupled receptor ontogeny and function
-
Angers S, Salahpour A, Bouvier M. Dimerization:an emerging concept for G protein-coupled receptor ontogeny and function. Annu Rev Pharmacol Toxicol 2002;42:409-435.
-
(2002)
Annu Rev Pharmacol Toxicol
, vol.42
, pp. 409-435
-
-
Angers, S.1
Salahpour, A.2
Bouvier, M.3
-
8
-
-
0042467972
-
Molecular mechanisms and therapeutical implications of intramembrane receptor/receptor interactions among heptahelical receptors with examples from the striatopallidal GABA neurons
-
Agnati LF, Ferre S, Lluis C, Franco R, Fuxe K. Molecular mechanisms and therapeutical implications of intramembrane receptor/receptor interactions among heptahelical receptors with examples from the striatopallidal GABA neurons. Pharmacol Rev 2003;55:509-550.
-
(2003)
Pharmacol Rev
, vol.55
, pp. 509-550
-
-
Agnati, L.F.1
Ferre, S.2
Lluis, C.3
Franco, R.4
Fuxe, K.5
-
9
-
-
0347320632
-
G-protein coupled receptor oligomerization in neuroendocrine pathways
-
Kroeger KM, Pfleger KD, Eidne KA. G-protein coupled receptor oligomerization in neuroendocrine pathways. Front Neuroendocrinol 2003;24:254-278.
-
(2003)
Front Neuroendocrinol
, vol.24
, pp. 254-278
-
-
Kroeger, K.M.1
Pfleger, K.D.2
Eidne, K.A.3
-
10
-
-
1242276192
-
Roles of G-protein-coupled receptor dimerization
-
Terrillon S, Bouvier M. Roles of G-protein-coupled receptor dimerization. EMBO Rep 2004;5:30-34.
-
(2004)
EMBO Rep
, vol.5
, pp. 30-34
-
-
Terrillon, S.1
Bouvier, M.2
-
12
-
-
0017190266
-
Negative cooperativity among beta-adrenergic receptors in frog erythrocyte membranes
-
Limbird LE, Lefkowitz RJ. Negative cooperativity among beta-adrenergic receptors in frog erythrocyte membranes. J Biol Chem 1976;251:5007-5014.
-
(1976)
J Biol Chem
, vol.251
, pp. 5007-5014
-
-
Limbird, L.E.1
Lefkowitz, R.J.2
-
13
-
-
0029753014
-
Agonist stimulation increases the turnover rate of beta 2AR-bound palmitate and promotes receptor depalmitoylation
-
Loisel TP, Adam L, Hebert TE, Bouvier M. Agonist stimulation increases the turnover rate of beta 2AR-bound palmitate and promotes receptor depalmitoylation. Biochemistry 1996;35:15923-15932
-
(1996)
Biochemistry
, vol.35
, pp. 15923-15932
-
-
Loisel, T.P.1
Adam, L.2
Hebert, T.E.3
Bouvier, M.4
-
14
-
-
0029666267
-
A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation
-
Hebert TE, Moffett S, Morello JP, Loisel TP, Bichet DG, Barret C, Bouvier M. A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation. J Biol Chem 1996;271:16384-16392.
-
(1996)
J Biol Chem
, vol.271
, pp. 16384-16392
-
-
Hebert, T.E.1
Moffett, S.2
Morello, J.P.3
Loisel, T.P.4
Bichet, D.G.5
Barret, C.6
Bouvier, M.7
-
15
-
-
0032519493
-
Functional rescue of a constitutively desensitized beta2AR through receptor dimerization
-
Hebert TE, Loisel TP, Adam L, Ethier N, Onge SS, Bouvier M. Functional rescue of a constitutively desensitized beta2AR through receptor dimerization. Biochem J 1998;330:287-293.
-
(1998)
Biochem J
, vol.330
, pp. 287-293
-
-
Hebert, T.E.1
Loisel, T.P.2
Adam, L.3
Ethier, N.4
Onge, S.S.5
Bouvier, M.6
-
16
-
-
0034724192
-
Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET)
-
Angers S, Salahpour A, Joly E, Hilairet S, Chelsky D, Dennis M, Bouvier M. Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET). Proc Natl Acad Sci USA 2000;97:3684-3689.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3684-3689
-
-
Angers, S.1
Salahpour, A.2
Joly, E.3
Hilairet, S.4
Chelsky, D.5
Dennis, M.6
Bouvier, M.7
-
18
-
-
0035958023
-
Monitoring receptor oligomerization using time-resolved fluorescence resonance energy transfer and bioluminescence resonance energy transfer. The human delta-opioid receptor displays constitutive oligomerization at the cell surface, which is not regulated by receptor occupancy
-
McVey M, Ramsay D, Kellett E, Rees S, Wilson S, Pope AJ, Milligan G. Monitoring receptor oligomerization using time-resolved fluorescence resonance energy transfer and bioluminescence resonance energy transfer. The human delta-opioid receptor displays constitutive oligomerization at the cell surface, which is not regulated by receptor occupancy. J Biol Chem 2001;276:14092-14099.
-
(2001)
J Biol Chem
, vol.276
, pp. 14092-14099
-
-
McVey, M.1
Ramsay, D.2
Kellett, E.3
Rees, S.4
Wilson, S.5
Pope, A.J.6
Milligan, G.7
-
20
-
-
0036462451
-
Oligomerization of opioid receptors:generation of novel signaling units
-
Levac BA, O'Dowd BF, George SR. Oligomerization of opioid receptors:generation of novel signaling units. Curr Opin Pharmacol 2002;2:76-81.
-
(2002)
Curr Opin Pharmacol
, vol.2
, pp. 76-81
-
-
Levac, B.A.1
O'Dowd, B.F.2
George, S.R.3
-
21
-
-
0034618268
-
AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration
-
AbdAlla S, Lother H, Quitterer U. AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration. Nature 2000;407:94-98.
-
(2000)
Nature
, vol.407
, pp. 94-98
-
-
AbdAlla, S.1
Lother, H.2
Quitterer, U.3
-
22
-
-
0034785580
-
Increased AT(1) receptor heterodimers in preeclampsia mediate enhanced angiotensin II responsiveness
-
AbdAlla S, Lother H, el Massiery A, Quitterer U. Increased AT(1) receptor heterodimers in preeclampsia mediate enhanced angiotensin II responsiveness. Nat Med 2001;7:1003-1009.
-
(2001)
Nat Med
, vol.7
, pp. 1003-1009
-
-
AbdAlla, S.1
Lother, H.2
El Massiery, A.3
Quitterer, U.4
-
23
-
-
1242274647
-
Heterodimerization of V1a and V2 vasopressin receptors determines the interaction with beta-arrestin and their trafficking patterns
-
Terrillon S, Barberis C, Bouvier M. Heterodimerization of V1a and V2 vasopressin receptors determines the interaction with beta-arrestin and their trafficking patterns. Proc Natl Acad Sci USA 2004;101:1548-1553.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 1548-1553
-
-
Terrillon, S.1
Barberis, C.2
Bouvier, M.3
-
24
-
-
10644269916
-
Oligomeric assembly of dopamine D(1) and glutamate NMDA receptors: Molecular mechanisms and functional implications
-
Fiorentini C, Missale C. Oligomeric assembly of dopamine D(1) and glutamate NMDA receptors: molecular mechanisms and functional implications. Biochem Soc Trans 2004;32:1025-1028.
-
(2004)
Biochem Soc Trans
, vol.32
, pp. 1025-1028
-
-
Fiorentini, C.1
Missale, C.2
-
25
-
-
0037426865
-
Atomic-force microscopy: Rhodopsin dimers in native disc membranes
-
Fotiadis D, Liang Y, Filipek S, Saperstein DA, Engel A, Palczewski K. Atomic-force microscopy: Rhodopsin dimers in native disc membranes. Nature 2003;421:127-128.
-
(2003)
Nature
, vol.421
, pp. 127-128
-
-
Fotiadis, D.1
Liang, Y.2
Filipek, S.3
Saperstein, D.A.4
Engel, A.5
Palczewski, K.6
-
26
-
-
0038159530
-
Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes
-
Liang Y, Fotiadis D, Filipek S, Saperstein DA, Palczewski K, Engel A. Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes. J Biol Chem 2003;278:21655-21662.
-
(2003)
J Biol Chem
, vol.278
, pp. 21655-21662
-
-
Liang, Y.1
Fotiadis, D.2
Filipek, S.3
Saperstein, D.A.4
Palczewski, K.5
Engel, A.6
-
27
-
-
10744224952
-
Receptor heteromerization in adenosine A2A receptor signaling: Relevance for striatal function and Parkinson's disease
-
Fuxe K, Agnati LF, Jacobsen K, Hillion J, Canals M, Torvinen M, Tinner-Staines B, Staines W, Rosin D, Terasmaa A, Popoli P, Leo G, Vergoni V, Lluis C, Ciruela F, Franco R, Ferre S. Receptor heteromerization in adenosine A2A receptor signaling: relevance for striatal function and Parkinson's disease. Neurology 2003;61: S19-S23.
-
(2003)
Neurology
, vol.61
-
-
Fuxe, K.1
Agnati, L.F.2
Jacobsen, K.3
Hillion, J.4
Canals, M.5
Torvinen, M.6
Tinner-Staines, B.7
Staines, W.8
Rosin, D.9
Terasmaa, A.10
Popoli, P.11
Leo, G.12
Vergoni, V.13
Lluis, C.14
Ciruela, F.15
Franco, R.16
Ferre, S.17
-
28
-
-
0037124032
-
Coaggregation, cointernalization, and codesensitization of adenosine A2A receptors and dopamine D2 receptors
-
Hillion J, Canals M, Torvinen M, Casado V, Scott R, Terasmaa A, Hansson A, Watson S, Olah ME, Mallol J, Canela EI, Zoli M, Agnati LF, Ibanez CF, Lluis C, Franco R, Ferre S, Fuxe K. Coaggregation, cointernalization, and codesensitization of adenosine A2A receptors and dopamine D2 receptors. J Biol Chem 2002;277:18091-18097.
-
(2002)
J Biol Chem
, vol.277
, pp. 18091-18097
-
-
Hillion, J.1
Canals, M.2
Torvinen, M.3
Casado, V.4
Scott, R.5
Terasmaa, A.6
Hansson, A.7
Watson, S.8
Olah, M.E.9
Mallol, J.10
Canela, E.I.11
Zoli, M.12
Agnati, L.F.13
Ibanez, C.F.14
Lluis, C.15
Franco, R.16
Ferre, S.17
Fuxe, K.18
-
29
-
-
0034688225
-
Direct protein-protein coupling enables cross-talk between dopamine D5 and gamma-aminobutyric acid A receptors
-
Liu F, Wan Q, Pristupa ZB, Yu XM, Wang YT, Niznik HB. Direct protein-protein coupling enables cross-talk between dopamine D5 and gamma-aminobutyric acid A receptors. Nature 2000;403:274-280.
-
(2000)
Nature
, vol.403
, pp. 274-280
-
-
Liu, F.1
Wan, Q.2
Pristupa, Z.B.3
Yu, X.M.4
Wang, Y.T.5
Niznik, H.B.6
-
30
-
-
0033516576
-
Identification and molecular characterization of m3 muscarinic receptor dimers
-
Zeng FY, Wess J. Identification and molecular characterization of m3 muscarinic receptor dimers. J Biol Chem 1999;274:19487-19497.
-
(1999)
J Biol Chem
, vol.274
, pp. 19487-19497
-
-
Zeng, F.Y.1
Wess, J.2
-
31
-
-
0033801789
-
Molecular aspects of muscarinic receptor dimerization
-
Zeng F, Wess J. Molecular aspects of muscarinic receptor dimerization. Neuropsychopharmacology 2000;23:S19-31.
-
(2000)
Neuropsychopharmacology
, vol.23
-
-
Zeng, F.1
Wess, J.2
-
32
-
-
0032422771
-
Domain swapping in G-protein coupled receptor dimers
-
Gouldson PR, Snell CR, Bywater RP, Higgs C, Reynolds CA. Domain swapping in G-protein coupled receptor dimers. Protein Eng 1998;11:1181-1193.
-
(1998)
Protein Eng
, vol.11
, pp. 1181-1193
-
-
Gouldson, P.R.1
Snell, C.R.2
Bywater, R.P.3
Higgs, C.4
Reynolds, C.A.5
-
33
-
-
0033806215
-
Dimerization and domain swapping in G-protein-coupled receptors: A computational study
-
Gouldson PR, Higgs C, Smith RE, Dean MK, Gkoutos GV, Reynolds CA. Dimerization and domain swapping in G-protein-coupled receptors: a computational study. Neuropsychopharmacology 2000;23:S60-S77.
-
(2000)
Neuropsychopharmacology
, vol.23
-
-
Gouldson, P.R.1
Higgs, C.2
Smith, R.E.3
Dean, M.K.4
Gkoutos, G.V.5
Reynolds, C.A.6
-
34
-
-
0027533276
-
Reconstitution of functional muscarinic receptors by coexpression of amino- and carboxyl-terminal receptor fragments
-
Maggio R, Vogel Z, Wess, J. Reconstitution of functional muscarinic receptors by coexpression of amino- and carboxyl-terminal receptor fragments. FEBS Lett 1993;319:195-200.
-
(1993)
FEBS Lett
, vol.319
, pp. 195-200
-
-
Maggio, R.1
Vogel, Z.2
Wess, J.3
-
35
-
-
0027467848
-
Coexpression studies with mutant muscarinic/adrenergic receptors provide evidence for intermolecular "cross-talk" between G-protein-linked receptors
-
Maggio R, Vogel Z, Wess J. Coexpression studies with mutant muscarinic/adrenergic receptors provide evidence for intermolecular "cross-talk" between G-protein-linked receptors. Proc Natl Acad Sci U S A 1993;90:3103-3107.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 3103-3107
-
-
Maggio, R.1
Vogel, Z.2
Wess, J.3
-
36
-
-
3042551375
-
Ligand-induced rearrangement of the dimeric metabotropic glutamate receptor lalpha
-
Tateyama M, Abe H, Nakata H, Saito O, Kubo Y. Ligand-induced rearrangement of the dimeric metabotropic glutamate receptor lalpha. Nat Struct Mol Biol 2004;11:637-642.
-
(2004)
Nat Struct Mol Biol
, vol.11
, pp. 637-642
-
-
Tateyama, M.1
Abe, H.2
Nakata, H.3
Saito, O.4
Kubo, Y.5
-
37
-
-
0034623081
-
Cryptic dimer interface and domain organization of the extracellular region of metabotropic glutamate receptor subtype 1
-
Tsuji Y, Shimada Y, Takeshita T, Kajimura N, Nomura S, Sekiyama N, Otomo J, Usukura J, Nakanishi S, Jingami H. Cryptic dimer interface and domain organization of the extracellular region of metabotropic glutamate receptor subtype 1. J Biol Chem 2000;275:28144-28151.
-
(2000)
J Biol Chem
, vol.275
, pp. 28144-28151
-
-
Tsuji, Y.1
Shimada, Y.2
Takeshita, T.3
Kajimura, N.4
Nomura, S.5
Sekiyama, N.6
Otomo, J.7
Usukura, J.8
Nakanishi, S.9
Jingami, H.10
-
38
-
-
0035164277
-
Covalent and noncovalent interactions mediate metabotropic glutamate receptor mGlu5 dimerization
-
Romano C, Miller JK, Hyrc K, Dikranian S, Mennerick S, Takeuchi Y, Goldberg MP, O'Malley KL. Covalent and noncovalent interactions mediate metabotropic glutamate receptor mGlu5 dimerization. Mol Pharmacol 2001;59:46-53.
-
(2001)
Mol Pharmacol
, vol.59
, pp. 46-53
-
-
Romano, C.1
Miller, J.K.2
Hyrc, K.3
Dikranian, S.4
Mennerick, S.5
Takeuchi, Y.6
Goldberg, M.P.7
O'Malley, K.L.8
-
39
-
-
0035895907
-
The extracellular calcium-sensing receptor dimerizes through multiple types of intermolecular interactions
-
Zhang Z, Sun S, Quinn SJ, Brown EM, Bai M. The extracellular calcium-sensing receptor dimerizes through multiple types of intermolecular interactions. J Biol Chem 2001;276:5316-5322.
-
(2001)
J Biol Chem
, vol.276
, pp. 5316-5322
-
-
Zhang, Z.1
Sun, S.2
Quinn, S.J.3
Brown, E.M.4
Bai, M.5
-
40
-
-
0032542382
-
GABA(B)-receptor subtypes assemble into functional heteromeric complexes
-
Kaupmann K, Malitschek B, Schuler V, Heid J, Froestl W, Beck P, Mosbacher J, Bischoff S, Kulik A, Shigemoto R, Karschin A, Bettler B. GABA(B)-receptor subtypes assemble into functional heteromeric complexes. Nature 1998;396:683-687.
-
(1998)
Nature
, vol.396
, pp. 683-687
-
-
Kaupmann, K.1
Malitschek, B.2
Schuler, V.3
Heid, J.4
Froestl, W.5
Beck, P.6
Mosbacher, J.7
Bischoff, S.8
Kulik, A.9
Shigemoto, R.10
Karschin, A.11
Bettler, B.12
-
41
-
-
0030567986
-
Dopamine D2 receptor dimers and receptor-blocking peptides
-
Ng GY, O'Dowd BF, Lee SP, Chung HT, Brann MR, Seeman P, George SR. Dopamine D2 receptor dimers and receptor-blocking peptides. Biochem Biophys Res Commun 1996;227:200-204.
-
(1996)
Biochem Biophys Res Commun
, vol.227
, pp. 200-204
-
-
Ng, G.Y.1
O'Dowd, B.F.2
Lee, S.P.3
Chung, H.T.4
Brann, M.R.5
Seeman, P.6
George, S.R.7
-
42
-
-
0038576278
-
The fourth transmembrane segment forms the interface of the dopamine D2 receptor homodimer
-
Guo W, Shi L, Javitch JA. The fourth transmembrane segment forms the interface of the dopamine D2 receptor homodimer. J Biol Chem 2003;278:4385-4388.
-
(2003)
J Biol Chem
, vol.278
, pp. 4385-4388
-
-
Guo, W.1
Shi, L.2
Javitch, J.A.3
-
43
-
-
0141431029
-
D2 dopamine receptor homodimerization is mediated by multiple sites of interaction, including an intermolecular interaction involving transmembrane domain 4
-
Lee SP, O'Dowd BF, Rajaram RD, Nguyen T, George SR. D2 dopamine receptor homodimerization is mediated by multiple sites of interaction, including an intermolecular interaction involving transmembrane domain 4. Biochemistry 2003;42:11023-11031.
-
(2003)
Biochemistry
, vol.42
, pp. 11023-11031
-
-
Lee, S.P.1
O'Dowd, B.F.2
Rajaram, R.D.3
Nguyen, T.4
George, S.R.5
-
44
-
-
0035866088
-
C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(b) receptors
-
Pagano A, Rovelli G, Mosbacher J, Lohmann T, Duthey B, Stauffer D, Ristig D, Schuler V, Meigel I, Lampert C, Stein T, Prezeau L, Blahos J, Pin J, Froestl W, Kuhn R, Heid J, Kaupmann K, Bettler B. C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(b) receptors. J Neurosci 2001;21:1189-1202.
-
(2001)
J Neurosci
, vol.21
, pp. 1189-1202
-
-
Pagano, A.1
Rovelli, G.2
Mosbacher, J.3
Lohmann, T.4
Duthey, B.5
Stauffer, D.6
Ristig, D.7
Schuler, V.8
Meigel, I.9
Lampert, C.10
Stein, T.11
Prezeau, L.12
Blahos, J.13
Pin, J.14
Froestl, W.15
Kuhn, R.16
Heid, J.17
Kaupmann, K.18
Bettler, B.19
-
45
-
-
0032574982
-
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
-
McLatchie LM, Fraser NJ, Main MJ, Wise A, Brown J, Thompson N, Solari R, Lee MG, Foord SM. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature 1998;393:333-339.
-
(1998)
Nature
, vol.393
, pp. 333-339
-
-
McLatchie, L.M.1
Fraser, N.J.2
Main, M.J.3
Wise, A.4
Brown, J.5
Thompson, N.6
Solari, R.7
Lee, M.G.8
Foord, S.M.9
-
46
-
-
0031565729
-
Analysis of protein-protein interaction sites using surface patches
-
Jones S, Thornton JM. Analysis of protein-protein interaction sites using surface patches. J Mol Biol 1997;272:121-132.
-
(1997)
J Mol Biol
, vol.272
, pp. 121-132
-
-
Jones, S.1
Thornton, J.M.2
-
47
-
-
0031565725
-
Prediction of protein-protein interaction sites using patch analysis
-
Jones S, Thornton JM. Prediction of protein-protein interaction sites using patch analysis. J Mol Biol 1997;272:133-143.
-
(1997)
J Mol Biol
, vol.272
, pp. 133-143
-
-
Jones, S.1
Thornton, J.M.2
-
48
-
-
0029913807
-
An evolutionary trace method defines binding surfaces common to protein families
-
Lichtarge O, Bourne HR, Cohen FE. An evolutionary trace method defines binding surfaces common to protein families. J Mol Biol 1996;257:342-358.
-
(1996)
J Mol Biol
, vol.257
, pp. 342-358
-
-
Lichtarge, O.1
Bourne, H.R.2
Cohen, F.E.3
-
49
-
-
0038356582
-
Predicted protein-protein interaction sites from local sequence information
-
Ofran Y, Rost B. Predicted protein-protein interaction sites from local sequence information. FEBS Lett 2003;544:236-239.
-
(2003)
FEBS Lett
, vol.544
, pp. 236-239
-
-
Ofran, Y.1
Rost, B.2
-
50
-
-
0346220017
-
Dimerization in aminergic G-protein-coupled receptors: Application of a hidden-site class model of evolution
-
Soyer OS, Dimmic MW, Neubig RR, Goldstein RA. Dimerization in aminergic G-protein-coupled receptors: application of a hidden-site class model of evolution. Biochemistry 2003;42:14522-14531
-
(2003)
Biochemistry
, vol.42
, pp. 14522-14531
-
-
Soyer, O.S.1
Dimmic, M.W.2
Neubig, R.R.3
Goldstein, R.A.4
-
51
-
-
0032711731
-
Analysis of heregulin symmetry by weighted evolutionary tracing
-
Landgraf R, Fischer D, Eisenberg D. Analysis of heregulin symmetry by weighted evolutionary tracing. Protein Eng 1999;12:943-951.
-
(1999)
Protein Eng
, vol.12
, pp. 943-951
-
-
Landgraf, R.1
Fischer, D.2
Eisenberg, D.3
-
52
-
-
1542379652
-
Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions
-
Madabushi S, Gross AK, Philippi A, Meng EC, Wensel TG, Lichtarge O. Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions. J Biol Chem 2004;279:8126-8132.
-
(2004)
J Biol Chem
, vol.279
, pp. 8126-8132
-
-
Madabushi, S.1
Gross, A.K.2
Philippi, A.3
Meng, E.C.4
Wensel, T.G.5
Lichtarge, O.6
-
53
-
-
0034644783
-
Analysis and prediction of functional sub-types from protein sequence alignments
-
Hannenhalli SS, Russell RB. Analysis and prediction of functional sub-types from protein sequence alignments. J Mol Biol 2000;303: 61-76.
-
(2000)
J Mol Biol
, vol.303
, pp. 61-76
-
-
Hannenhalli, S.S.1
Russell, R.B.2
-
54
-
-
0035061686
-
Maximum-likelihood approach for gene family evolution under functional divergence
-
Gu X. Maximum-likelihood approach for gene family evolution under functional divergence. Mol Biol Evol 2001;18:453-464.
-
(2001)
Mol Biol Evol
, vol.18
, pp. 453-464
-
-
Gu, X.1
-
55
-
-
0037470597
-
Automatic methods for predicting functionally important residues
-
del Sol Mesa A, Pazos F, Valencia A. Automatic methods for predicting functionally important residues. J Mol Biol 2003;326: 1289-1302.
-
(2003)
J Mol Biol
, vol.326
, pp. 1289-1302
-
-
Del Sol Mesa, A.1
Pazos, F.2
Valencia, A.3
-
56
-
-
1242339659
-
A family of evolution-entropy hybrid methods for ranking protein residues by importance
-
Mihalek I, Res I, Lichtarge O. A family of evolution-entropy hybrid methods for ranking protein residues by importance. J Mol Biol 2004;336:1265-1282.
-
(2004)
J Mol Biol
, vol.336
, pp. 1265-1282
-
-
Mihalek, I.1
Res, I.2
Lichtarge, O.3
-
57
-
-
0036300444
-
Structural clusters of evolutionary trace residues are statistically significant and common in proteins
-
Madabushi S, Yao H, Marsh M, Kristensen DM, Philippi A, Sowa ME, Lichtarge O. Structural clusters of evolutionary trace residues are statistically significant and common in proteins. J Mol Biol 2002;316:139-154.
-
(2002)
J Mol Biol
, vol.316
, pp. 139-154
-
-
Madabushi, S.1
Yao, H.2
Marsh, M.3
Kristensen, D.M.4
Philippi, A.5
Sowa, M.E.6
Lichtarge, O.7
-
58
-
-
0035924184
-
Dimerization of G-protein-coupled receptors
-
Dean MK, Higgs C, Smith RE, Bywater RP, Snell CR, Scott PD, Upton GJ, Howe TJ, Reynolds CA. Dimerization of G-protein-coupled receptors. J Med Chem 2001;44:4595-4614.
-
(2001)
J Med Chem
, vol.44
, pp. 4595-4614
-
-
Dean, M.K.1
Higgs, C.2
Smith, R.E.3
Bywater, R.P.4
Snell, C.R.5
Scott, P.D.6
Upton, G.J.7
Howe, T.J.8
Reynolds, C.A.9
-
59
-
-
0034677745
-
Subtypes of the somatostatin receptor assemble as functional homo- and heterodimers
-
Rocheville M, Lange DC, Kumar U, Sasi R, Patel RC, Patel YC. Subtypes of the somatostatin receptor assemble as functional homo- and heterodimers. J Biol Chem 2000;275:7862-7869.
-
(2000)
J Biol Chem
, vol.275
, pp. 7862-7869
-
-
Rocheville, M.1
Lange, D.C.2
Kumar, U.3
Sasi, R.4
Patel, R.C.5
Patel, Y.C.6
-
60
-
-
0033578005
-
G-protein-coupled receptor heterodimerization modulates receptor function
-
Jordan BA, Devi LA. G-protein-coupled receptor heterodimerization modulates receptor function. Nature 1999;399:697-700.
-
(1999)
Nature
, vol.399
, pp. 697-700
-
-
Jordan, B.A.1
Devi, L.A.2
-
61
-
-
0034714335
-
Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties
-
George SR, Fan T, Xie Z, Tse R, Tam V, Varghese G, O'Dowd BF. Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties. J Biol Chem 2000;275:26128-26135.
-
(2000)
J Biol Chem
, vol.275
, pp. 26128-26135
-
-
George, S.R.1
Fan, T.2
Xie, Z.3
Tse, R.4
Tam, V.5
Varghese, G.6
O'Dowd, B.F.7
-
62
-
-
0034668742
-
Heterodimerization of mu and delta opioid receptors: A role in opiate synergy
-
Gomes I, Jordan BA, Gupta A, Trapaidze N, Nagy V, Devi LA. Heterodimerization of mu and delta opioid receptors: A role in opiate synergy. J Neurosci 2000;20:RC110.
-
(2000)
J Neurosci
, vol.20
-
-
Gomes, I.1
Jordan, B.A.2
Gupta, A.3
Trapaidze, N.4
Nagy, V.5
Devi, L.A.6
-
63
-
-
0035793079
-
Oligomerization of opioid receptors with beta 2-adrenergic receptors: A role in trafficking and mitogen-activated protein kinase activation
-
Jordan BA, Trapaidze N, Gomes I, Nivarthi R, Devi LA. Oligomerization of opioid receptors with beta 2-adrenergic receptors: a role in trafficking and mitogen-activated protein kinase activation. Proc Natl Acad Sci USA 2001;98:343-348.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 343-348
-
-
Jordan, B.A.1
Trapaidze, N.2
Gomes, I.3
Nivarthi, R.4
Devi, L.A.5
-
64
-
-
0035664761
-
Lipid-facing correlated mutations and dimerization in G-protein coupled receptors
-
Gouldson PR, Dean MK, Snell CR, Bywater RP, Gkoutos G, Reynolds CA. Lipid-facing correlated mutations and dimerization in G-protein coupled receptors. Protein Eng 2001;14:759-767.
-
(2001)
Protein Eng
, vol.14
, pp. 759-767
-
-
Gouldson, P.R.1
Dean, M.K.2
Snell, C.R.3
Bywater, R.P.4
Gkoutos, G.5
Reynolds, C.A.6
-
65
-
-
0032515074
-
A transmembrane domain-derived peptide inhibits D1 dopamine receptor function without affecting receptor oligomerization
-
George SR, Lee SP, Varghese G, Zeman PR, Seeman P, Ng GY, O'Dowd BF. A transmembrane domain-derived peptide inhibits D1 dopamine receptor function without affecting receptor oligomerization. J Biol Chem 1998;273:30244-30248.
-
(1998)
J Biol Chem
, vol.273
, pp. 30244-30248
-
-
George, S.R.1
Lee, S.P.2
Varghese, G.3
Zeman, P.R.4
Seeman, P.5
Ng, G.Y.6
O'Dowd, B.F.7
-
66
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
Palczewski K, Kumasaka T, Hori T, Behnke CA, Motoshima H, Fox BA, Le Trong I, Teller DC, Okada T, Stenkamp RE, Yamamoto M, Miyano M. Crystal structure of rhodopsin: A G protein-coupled receptor. Science 2000;289:739-745.
-
(2000)
Science
, vol.289
, pp. 739-745
-
-
Palczewski, K.1
Kumasaka, T.2
Hori, T.3
Behnke, C.A.4
Motoshima, H.5
Fox, B.A.6
Le Trong, I.7
Teller, D.C.8
Okada, T.9
Stenkamp, R.E.10
Yamamoto, M.11
Miyano, M.12
-
67
-
-
0037197848
-
Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography
-
Okada T, Fujiyoshi Y, Silow M, Navarro J, Landau EM, Shichida Y. Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography. Proc Natl Acad Sci USA 2002;99:5982-5987.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 5982-5987
-
-
Okada, T.1
Fujiyoshi, Y.2
Silow, M.3
Navarro, J.4
Landau, E.M.5
Shichida, Y.6
-
68
-
-
0037648337
-
Structure-based analysis of GPCR function: Conformational adaptation of both agonist and receptor upon leukotriene B4 binding to recombinant BLT1
-
Baneres JL, Martin A, Hullot P, Girard JP, Rossi JC, Parello J. Structure-based analysis of GPCR function: conformational adaptation of both agonist and receptor upon leukotriene B4 binding to recombinant BLT1. J Mol Biol 2003;329:801-814.
-
(2003)
J Mol Biol
, vol.329
, pp. 801-814
-
-
Baneres, J.L.1
Martin, A.2
Hullot, P.3
Girard, J.P.4
Rossi, J.C.5
Parello, J.6
-
69
-
-
0038392702
-
Structure-based analysis of GPCR function: Evidence for a novel pentameric assembly between the dimeric leukotriene B4 receptor BLT1 and the G-protein
-
Baneres JL, Parello J. Structure-based analysis of GPCR function: evidence for a novel pentameric assembly between the dimeric leukotriene B4 receptor BLT1 and the G-protein. J Mol Biol 2003;329:815-829.
-
(2003)
J Mol Biol
, vol.329
, pp. 815-829
-
-
Baneres, J.L.1
Parello, J.2
-
70
-
-
0031574072
-
The CLUSTAL X windows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools
-
Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG. The CLUSTAL X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 1997;25:4876-4882.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 4876-4882
-
-
Thompson, J.D.1
Gibson, T.J.2
Plewniak, F.3
Jeanmougin, F.4
Higgins, D.G.5
-
71
-
-
12944332482
-
-
http://www.mbio.ncsu.edu/BioEdit/bioedit.html
-
-
-
-
72
-
-
0036139211
-
MEGA2: Molecular evolutionary genetics analysis software
-
Kumar S, Tamura K, Jakobsen IB, Nei M. MEGA2: molecular evolutionary genetics analysis software. Bioinformatics 2001;17: 1244-1245.
-
(2001)
Bioinformatics
, vol.17
, pp. 1244-1245
-
-
Kumar, S.1
Tamura, K.2
Jakobsen, I.B.3
Nei, M.4
-
73
-
-
0035178383
-
Protein-protein interfaces: Analysis of amino acid conservation in homodimers
-
Valdar WS, Thornton JM. Protein-protein interfaces: analysis of amino acid conservation in homodimers. Proteins 2001;42:108-124.
-
(2001)
Proteins
, vol.42
, pp. 108-124
-
-
Valdar, W.S.1
Thornton, J.M.2
-
74
-
-
0028153788
-
A mutation data matrix for transmembrane proteins
-
Jones DT, Taylor WR, Thornton JM. A mutation data matrix for transmembrane proteins. FEBS Lett 1994;339:269-275.
-
(1994)
FEBS Lett
, vol.339
, pp. 269-275
-
-
Jones, D.T.1
Taylor, W.R.2
Thornton, J.M.3
-
75
-
-
0028043552
-
Position-based sequence weights
-
Henikoff S, Henikoff JG. Position-based sequence weights. J Mol Biol 1994;243:574-578.
-
(1994)
J Mol Biol
, vol.243
, pp. 574-578
-
-
Henikoff, S.1
Henikoff, J.G.2
-
76
-
-
12944255037
-
-
http://wolf.bms.umist.ac.uk/naccess/naccess.html
-
-
-
-
77
-
-
12944274039
-
-
http://www.umass.edu/microbio/rasmol/
-
-
-
-
78
-
-
12944277642
-
-
http://kr.expasy.org/spdbv/
-
-
-
-
79
-
-
0031547966
-
Electrostatic complementarity at protein/protein interfaces
-
McCoy AJ, Chandana Epa V, Colman PM. Electrostatic complementarity at protein/protein interfaces. J Mol Biol 1997;268:570-584.
-
(1997)
J Mol Biol
, vol.268
, pp. 570-584
-
-
McCoy, A.J.1
Chandana Epa, V.2
Colman, P.M.3
-
80
-
-
0032479179
-
Anatomy of hot spots in protein interfaces
-
Bogan AA, Thorn KS. Anatomy of hot spots in protein interfaces. J Mol Biol 1998;280:1-9.
-
(1998)
J Mol Biol
, vol.280
, pp. 1-9
-
-
Bogan, A.A.1
Thorn, K.S.2
-
81
-
-
0037093645
-
Dissecting protein-protein recognition sites
-
Chakrabarti P, Janin J. Dissecting protein-protein recognition sites. Proteins 2002;47:334-343.
-
(2002)
Proteins
, vol.47
, pp. 334-343
-
-
Chakrabarti, P.1
Janin, J.2
-
82
-
-
0037609791
-
Protein-protein interactions: Structurally conserved residues distinguish between binding sites and exposed protein surfaces
-
Ma B, Elkayam T, Wolfson H, Nussinov R. Protein-protein interactions: structurally conserved residues distinguish between binding sites and exposed protein surfaces. Proc Natl Acad Sci USA 2003;100:5772-5777.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 5772-5777
-
-
Ma, B.1
Elkayam, T.2
Wolfson, H.3
Nussinov, R.4
-
83
-
-
0037229456
-
Analysing six types of protein-protein interfaces
-
Ofran Y, Rost B. Analysing six types of protein-protein interfaces. J Mol Biol 2003;325:377-387.
-
(2003)
J Mol Biol
, vol.325
, pp. 377-387
-
-
Ofran, Y.1
Rost, B.2
-
84
-
-
0037474541
-
Structural characterisation and functional significance of transient protein-protein interactions
-
Nooren IM, Thornton JM. Structural characterisation and functional significance of transient protein-protein interactions. J Mol Biol 2003;325:991-1018.
-
(2003)
J Mol Biol
, vol.325
, pp. 991-1018
-
-
Nooren, I.M.1
Thornton, J.M.2
-
85
-
-
0346733329
-
Are protein-protein interfaces more conserved in sequence than the rest of the protein surface?
-
Caffrey DR, Somaroo S, Hughes JD, Mintseris J, Huang ES. Are protein-protein interfaces more conserved in sequence than the rest of the protein surface? Protein Sci 2004;13:190-202.
-
(2004)
Protein Sci
, vol.13
, pp. 190-202
-
-
Caffrey, D.R.1
Somaroo, S.2
Hughes, J.D.3
Mintseris, J.4
Huang, E.S.5
-
86
-
-
0034213559
-
Conservation of polar residues as hot spots at protein interfaces
-
Hu Z, Ma B, Wolfson H, Nussinov R. Conservation of polar residues as hot spots at protein interfaces. Proteins 2000;39:331-342.
-
(2000)
Proteins
, vol.39
, pp. 331-342
-
-
Hu, Z.1
Ma, B.2
Wolfson, H.3
Nussinov, R.4
-
87
-
-
4243978485
-
Association of a missense change in the D2 dopamine receptor with myoclonus dystonia
-
Klein C, Brin MF, Kramer P, Sena-Esteves M, de Leon D, Doheny D, Bressman S, Fahn S, Breakefield XO, Ozelius LJ. Association of a missense change in the D2 dopamine receptor with myoclonus dystonia. Proc Natl Acad Sci USA 1999;96:5173-5176.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 5173-5176
-
-
Klein, C.1
Brin, M.F.2
Kramer, P.3
Sena-Esteves, M.4
De Leon, D.5
Doheny, D.6
Bressman, S.7
Fahn, S.8
Breakefield, X.O.9
Ozelius, L.J.10
-
88
-
-
0034010735
-
Evaluation of the role of the D2 dopamine receptor in myoclonus dystonia
-
Klein C, Gurvich N, Sena-Esteves M, Bressman S, Brin MF, Ebersole BJ, Fink S, Forsgren L, Friedman J, Grimes D, Holmgren G, Kyllerman M, Lang AE, de Leon D, Leung J, Prioleau C, Raymond D, Sanner G, Saunders-Pullman R, Vieregge P, Wahlstrom J, Breakefield XO, Kramer PL, Ozelius LJ, Sealfon SC. Evaluation of the role of the D2 dopamine receptor in myoclonus dystonia. Ann Neurol 2000;47:369-373.
-
(2000)
Ann Neurol
, vol.47
, pp. 369-373
-
-
Klein, C.1
Gurvich, N.2
Sena-Esteves, M.3
Bressman, S.4
Brin, M.F.5
Ebersole, B.J.6
Fink, S.7
Forsgren, L.8
Friedman, J.9
Grimes, D.10
Holmgren, G.11
Kyllerman, M.12
Lang, A.E.13
De Leon, D.14
Leung, J.15
Prioleau, C.16
Raymond, D.17
Sanner, G.18
Saunders-Pullman, R.19
Vieregge, P.20
Wahlstrom, J.21
Breakefield, X.O.22
Kramer, P.L.23
Ozelius, L.J.24
Sealfon, S.C.25
more..
-
89
-
-
0034682445
-
Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes
-
Gines S, Hillion J, Torvinen M, Le Crom S, Casado V, Canela EI, Rondin S, Lew JY, Watson S, Zoli M, Agnati LF, Verniera P, Lluis C, Ferre S, Fuxe K, Franco R. Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes. Proc Natl Acad Sci USA 2000;97:8606-8611.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 8606-8611
-
-
Gines, S.1
Hillion, J.2
Torvinen, M.3
Le Crom, S.4
Casado, V.5
Canela, E.I.6
Rondin, S.7
Lew, J.Y.8
Watson, S.9
Zoli, M.10
Agnati, L.F.11
Verniera, P.12
Lluis, C.13
Ferre, S.14
Fuxe, K.15
Franco, R.16
-
90
-
-
0030861647
-
Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia
-
Ferre S, Fredholm BB, Morelli M, Popoli P, Fuxe K. Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia. Trends Neurosci 1997;20:482-487.
-
(1997)
Trends Neurosci
, vol.20
, pp. 482-487
-
-
Ferre, S.1
Fredholm, B.B.2
Morelli, M.3
Popoli, P.4
Fuxe, K.5
-
91
-
-
0027050182
-
Sequence specificity in the dimerization of transmembrane alpha-helices
-
Lemmon MA, Flanagan JM, Treutlein HR, Zhang J, Engelman DM. Sequence specificity in the dimerization of transmembrane alpha-helices. Biochemistry 1992;31:12719-12725.
-
(1992)
Biochemistry
, vol.31
, pp. 12719-12725
-
-
Lemmon, M.A.1
Flanagan, J.M.2
Treutlein, H.R.3
Zhang, J.4
Engelman, D.M.5
-
92
-
-
0026686793
-
Glycophorin A dimerization is driven by specific interactions between transmembrane alpha-helices
-
Lemmon MA, Flanagan JM, Hunt JF, Adair BD, Bormann BJ, Dempsey CE, Engelman DM. Glycophorin A dimerization is driven by specific interactions between transmembrane alpha-helices. J Biol Chem 1992;267:7683-7689.
-
(1992)
J Biol Chem
, vol.267
, pp. 7683-7689
-
-
Lemmon, M.A.1
Flanagan, J.M.2
Hunt, J.F.3
Adair, B.D.4
Bormann, B.J.5
Dempsey, C.E.6
Engelman, D.M.7
-
93
-
-
0035979146
-
The Calpha -H...O hydrogen bond: A determinant of stability and specificity in transmembrane helix interactions
-
Senes A, Ubarretxena-Belandia I, Engelman DM. The Calpha -H...O hydrogen bond: a determinant of stability and specificity in transmembrane helix interactions. Proc Natl Acad Sci USA 2001;98:9056-9061.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9056-9061
-
-
Senes, A.1
Ubarretxena-Belandia, I.2
Engelman, D.M.3
-
94
-
-
0024110575
-
Cysteine residues 110 and 187 are essential for the formation of correct structure in bovine rhodopsin
-
Karnik SS, Sakmar TP, Chen HB, Khorana HG. Cysteine residues 110 and 187 are essential for the formation of correct structure in bovine rhodopsin. Proc Natl Acad Sci USA 1988;85:8459-8463.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 8459-8463
-
-
Karnik, S.S.1
Sakmar, T.P.2
Chen, H.B.3
Khorana, H.G.4
-
96
-
-
0026609104
-
The distribution of charged amino acids in mitochondrial inner-membrane proteins suggests different modes of membrane integration for nuclearly and mitochondrially encoded proteins
-
Gavel Y, von Heijne G. The distribution of charged amino acids in mitochondrial inner-membrane proteins suggests different modes of membrane integration for nuclearly and mitochondrially encoded proteins. Eur J Biochem 1992;205:1207-1215.
-
(1992)
Eur J Biochem
, vol.205
, pp. 1207-1215
-
-
Gavel, Y.1
Von Heijne, G.2
|