Apoptosis of murine melanoma B16-BL6 cells induced by quercetin targeting mitochondria, inhibiting expression of PKC-α and translocating PKC-δ

Cancer Chemotherapy and Pharmacology

Volumn 55, Issue 3, 2005, Pages 251-262

  Zhang, Xian Ming ^a   Chen, Jia ^a   Xia, Yu Gui ^a   Xu, Qiang ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Apoptosis; Bcl 2; Caspase 3; Mitochondria; Murine melanoma B16 BL6 cell; PKC and PKC ; Quercetin

Indexed keywords

CASPASE; CASPASE 3; DNA FRAGMENT; DOXORUBICIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C DELTA; QUERCETIN;

ANIMAL CELL; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL NUCLEUS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DETERMINATION; DRUG TARGETING; ENZYME ACTIVITY; FLUORESCENCE MICROSCOPY; GENE TRANSLOCATION; INHIBITION KINETICS; MELANOMA; MELANOMA CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPECTROSCOPY; STATISTICAL SIGNIFICANCE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; CASPASE 3; CASPASES; DNA FRAGMENTATION; ENZYME INHIBITORS; MELANOMA, EXPERIMENTAL; MEMBRANE POTENTIALS; MICE; MITOCHONDRIA; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; PROTEIN KINASE C-DELTA; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-BCL-2; QUERCETIN; TUMOR CELLS, CULTURED;

EID: 12444337495     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-004-0863-5     Document Type: Article

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