Vibrationally Enhanced Hydrogen Tunneling in the Escherichia coli Thymidylate Synthase Catalyzed Reaction

Biochemistry

Volumn 43, Issue 7, 2004, Pages 1998-2006

  Agrawal, Nitish ^a   Hong, Baoyu ^a   Mihai, Cornelia ^a   Kohen, Amnon ^a  

^a E11 SSH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ENERGY; BIOCHEMISTRY; CATALYSIS; CHEMICAL BONDS; ESCHERICHIA COLI; ISOTOPES; RATE CONSTANTS;

KINETIC ISOTOPE EFFECTS (KIE); RATE-DETERMINING STEPS;

ENZYMES;

HYDROGEN; ISOTOPE; THYMIDYLATE SYNTHASE;

ARTICLE; CALCULATION; CATALYSIS; CHEMICAL REACTION KINETICS; COVALENT BOND; ENERGY; ENZYME MECHANISM; ESCHERICHIA COLI; NONHUMAN; PREDICTION; PRIORITY JOURNAL; QUANTUM MECHANICS; TEMPERATURE DEPENDENCE; VELOCITY; VIBRATION;

CARBON RADIOISOTOPES; CATALYSIS; DEOXYURACIL NUCLEOTIDES; DEUTERIUM; DEUTERIUM EXCHANGE MEASUREMENT; ELECTRON TRANSPORT; ENZYME ACTIVATION; ESCHERICHIA COLI PROTEINS; HYDROGEN; KINETICS; TEMPERATURE; TETRAHYDROFOLATES; THERMODYNAMICS; THYMIDYLATE SYNTHASE;

ARRHENIUS; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

EID: 1242307783     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi036124g     Document Type: Article

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