Toll-like receptors: Physiological functions and implication in the pathogenesis of rheumatic diseases;Receptory toll-podobne: Znaczenie fizjologiczne i udział w patogenezie chorób reumatycznych

Reumatologia

Volumn 42, Issue 4, 2004, Pages 551-566

  Kontny, Ewa ^a,b   Rudnicka, Weronika ^a,b   Maśliński, Włodzimierz ^a,b  

^a Z Zakladu Patofizjologii I I ^*  (Poland)

^b INSTITUTE OF RHEUMATOLOGY   (Poland)

Author keywords

Immunopathogenesis; Rheumatic diseases; Toll like receptors

Indexed keywords

BACTERIAL DNA; CHEMOKINE; CYTOKINE; FIBRONECTIN; HEAT SHOCK PROTEIN; HYALURONIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 6; LIGAND; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA; VIRUS RNA;

AUTOIMMUNITY; B LYMPHOCYTE; CELL FUNCTION; CELL MATURATION; DENDRITIC CELL; FIBROBLAST; HUMORAL IMMUNITY; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATION; INNATE IMMUNITY; MICROORGANISM DETECTION; PATHOGENESIS; PHAGOCYTE; PROTEIN INTERACTION; REVIEW; RHEUMATIC DISEASE; T LYMPHOCYTE; TH1 CELL; TH2 CELL;

EID: 12344326643     PISSN: 00346233     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (58)

1. Akira S., Takeda K., Kaisho T. et al.: Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol., 2001, 2, 675.
2. Anders H.J., Banas B., Schlöndorff D.: Signaling danger: Toll-like receptors and their potential roles in kidney disease. J. Am. Soc. Nephrol., 2004, 15, 854.
3. Arend W.P.: The innate immune system in rheumatoid arthritis. Arthritis Rheum., 2001, 44, 224.
4. Barton G. M., Medzhitov R.: Toll-like receptor signaling pathways. Science, 2003, 300, 1524.
5. + dendritic cells. J. Immunol., 2001, 166, 5000.
6. Bell J. K., Mullen G.E.D., Leifer C.A. et al.: Leucine-rich repeats and pathogen recognition in Toll-like receptors. Trends Immunol., 2003, 24, 528.
7. Bernasconi N.L., Onai N., Lanzavecchia A.: A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells. Blood, 2003, 101, 4500.
8. + T cells from the target organ of patients with rheumatoid arthritis. Eur. J. Immunol., 2003, 33, 215.
9. Caramalho I., Lopes-Carvalho T., Ostler D. et al.: Regulatory T cells selectively express toll-like receptors and are activated by lipopolisaccharide. J. Exp. Med., 2003, 197, 403.
10. Deng G.M., Milsson I.M., Verdrengh M. et al.: Intra-artricularly localized bacterial DNA containing CpG motifs induces arthritis. Nat. Med., 1999, 5, 702.
11. Deng G.M., Verdrengh M., Liu Z.Q. et al.: The major role of macrophages and their product tumor necrosis factor α in the induction of arthritis triggered by bacterial DNA containing CpG motifs. Arthritis Rheum., 2000, 43, 2283.
12. Diebold S.S., Kaisho T., Hemmi H. et al.: Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 2004, 303, 1529.
13. Dillon S., Agrawal A., Van Dyke T. et al.: A toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells. J. Immunol., 2004, 172, 4733.
14. Fukao T., Koyasu S.: PI3K and negative regulation of TLR signaling. Trends Immunol., 2003, 24, 358.
15. Heil F., Hemmi H., Hochrein H. et al.: Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science, 2004, 303, 1526.
16. Herzog P.J., O'Neill L.A., Hamilton J.A.: The interferon in TLR signaling: more than just antiviral. Trends Immunol., 2003, 24, 534.
17. Hornung V, Rothenfusser S., Britsch S. et al.: Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J. Immunol., 2002, 168, 4531.
18. Ito T., Amakawa R., Kaisho T. et al.: Interferon-α and interleukin-12 are induced differentially by toll-like receptor 7 ligands in human blood dendritic cell subsets. J. Exp. Med., 2002, 195, 1507.
19. Johnson G.B., Brunn G.J., Kodaira Y. et al.: Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by toll-like receptor 4. J. Immunol., 2002, 168, 5233.
20. Johnson G.B., Brunn G.J., Tang A.H. et al.: Evolutionary clues to the functions of the toll-like family as surveillance receptors. Trends Immunol., 2003, 24, 19.
21. Kadowaki N., Ho S., Antonenko S. et al.: Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. J. Exp. Med., 2001, 194, 863.
22. Kaisho T., Akira S.: Dendritic-cell function in toll-like receptor- and MyD88-knockout mice. Trends Immunol., 2001, 22, 78.
23. Kilding R., Akil M., Till S. et al.: A biologically important single nucleotide polymorphism within the toll-like receptor-4 gene is not associated with rheumatoid arthritis. Clin. Exp. Rheumatol., 2003, 21, 340.
24. Kyburz D., Rethage J., Seibl R. et al.: Bacterial peptidoglycans but not CpG oligonucleotides activate synovial fibroblast by toll-like receptor signaling. Arthritis Rheum., 2003, 48, 642.
25. Leadbetter E.A., Rifkin I.R., Hohlbaum A.M. et al.: Chromatin-IgG complexes activate B cells by dual engagement of IgM and toll-like receptors. Nature, 2002, 416, 603.
26. Liu Z.Q., Deng G.M., Foster S. et al: Staphylococcal peptidoglycans induce arthritis. Arthritis Res., 2001, 3, 375.
27. Lohmander L.S., Dahlberg L., Ryd L. et al.: Increased level of proteoglycan fragment in knee joint fluid after injury. Arthritis Rheum., 1989, 32, 1434.
28. Lucas M., Stuart L.M., Savill J. et al.: Apoptotic cells and innate immune stimuli combine to regulate macrophage cytokine secretion. J. Immunol., 2003, 171, 2610.
29. Maloy K.J., Powrie F.: Regulatory T cells in the control of immune pathology. Nat. Immunol., 2001, 2, 816.
30. Miyake K.: Endotoxin recognition molecules, toll-like receptor 4-MD-2. Semin. Immunol., 2004, 16, 11.
31. Miyata M., Kobayashi H., Sasajima T. et al.: Unmethylated oligo-DNA containing CpG motifs aggravates collagen-induced arthritis in mice. Arthritis Rheum., 2000, 43, 2578.
32. Nagase H., Okugawa S., Ota Y. et al.: Expression and function of toll-like receptors in eosinophils: activation by toll-like receptor 7 ligand. J. Immunol., 2003, 171: 3977.
33. Nolan K.F., Strong V, Soler D. et al: IL-10-conditioned dendritic cells, decomissined for recruitment of adaptive immunity, elicit innate inflammatory gene products in response to danger signals. J. Immunol., 2004, 172, 2201.
34. Ohshima S., Saeki Y., Mima T. et al.: Interleukin 6 plays a key role in the development of antigen-induced arthritis. Proc. Natl. Acad. Sci. USA, 1998, 95, 8222.
35. O'Neill L.A.J.: Toll-like receptor signal transduction and the tailoring of innate immunity: a role for Mal? Trends Immunol., 2002, 23, 296.
36. O'Neill L.A.J.: SIGIRR puts the breaks on toll-like receptors. Nat. Immunol., 2003, 4, 823.
37. O'Neill L.A.J.: After the toll rush. Science, 2004, 303, 1481.
38. + T-cell-mediated suppression by dendritic cells. Science, 2003, 299, 1033.
39. Pasare Ch., Medzhitov R.: Toll-like receptors and acquired immunity. Semin. Immunol., 2004, 16, 23.
40. Radstake T.R.D.J., Franke B., Haussen S. et. al.: The toll-like receptor 4 Asp299Gly functional variant is associated with decreased rheumatoid arthritis disease susceptibility but does not influence disease severity and/or outcome. Arthritis Rheum., 2004, 50, 999.
41. Rehli M.: Of mice and men: species variations of toll-like receptor expression. Trends Immunol., 2002, 23, 375.
42. Reis e Sousa C.: Toll-like receptors and dendritic cells: for whom the bug tolls. Semin. Immunol., 2004, 16, 27.
43. Rui L., Vinuesa C.G., Blasioli J. et al.: Resistance to CpG DNA-induced autoimmunity through tolerogenic B cell antigen receptor ERK signaling. Nat. Immunol., 2003, 4, 594.
44. Sanchez E., Orozco G., Lopez-Nevot M.A. et al.: Polymorphisms of toll-like receptor 2 and 4 genes in rheumatoid arthritis and systemic lupus erythematosus. Tiss. Antig., 2004, 63, 54.
45. Schwarz K., Storni T., Manolova V. et al.: Role of toll-like receptors in costimulating cytotoxic T cell responses. Eur. J. Immunol., 2003, 33, 1465.
46. Seibl R., Birchler T., Loelinger S. et al.: Expression and regulation of toll-like receptor 2 in rheumatoid arthritis synovium. Am. J. Pathol., 2003, 162, 1221.
47. Seya T., Akazawa T., Uehori J. et. al.: Role of toll-like receptors and their adaptors in adjuvant immunotherapy for cancer. Anticancer Res., 2003, 23, 4369.
48. Sing A., Rost D., Tvardovskaia N. et al.: Yershinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression. J. Exp. Med., 2002, 196, 1017.
49. Takeda K., Akira S.: TLR signaling pathways. Semin. Immunol., 2004, 16, 3.
50. Takeshita F., Gursel I., Ishii K.J. et al.: Signal transduction pathways mediated by the interaction of CpG DNA with toll-like receptor 9. Semin. Immunol., 2004, 16, 17.
51. Triantafilou M., Triantafilou K.: Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster. Trends Immunol., 2002, 23, 301.
52. Uhlmann E., Vollmer J.: Recent advances in the development of immunostimulatory oligonucleotides. Curr. Opin. Drug Discov. Devel., 2003, 6, 204.
53. Van der Heijden I.M., Wilbrink B., Tchetuerikov I. et al.: Presence of bacterial DNA and bacterial peptidoglycans in joints of patients with rheumatoid arthritis and other arthritides. Arthritis Rheum., 2000, 43, 593.
54. Vinuesa C.G., Goodnow Ch.C.: DNA drives autoimmunity. Nature, 2002, 416, 595.
55. Williams B.R.G., Sen G.C.: A viral on/off switch for interferon. Science, 2003, 300, 1100.
56. Yamamoto M., Sato S., Hemmi H. et al.: Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 2003, 301, 640.
57. Zare F., Bokarewa M., Nenonen N. et al.: Arthritogenic properties of double-strand (viral) RNA. J. Immunol., 2004, 172, 5656.
58. Zhang D., Zhang G., Hayden M.S. et al. : A toll-like receptor that prevents infection by uropathogenic bacteria. Science, 2004, 303, 1522.