-
1
-
-
0031891656
-
Cell-associated activation of latent transforming growth factor-β by calpain
-
Abe, M., Oda, N. and Sato, Y. (1998) Cell-associated activation of latent transforming growth factor-β by calpain. J Cell Physiol 174:186-193.
-
(1998)
J Cell Physiol
, vol.174
, pp. 186-193
-
-
Abe, M.1
Oda, N.2
Sato, Y.3
-
2
-
-
0030868422
-
Thrombospondin-1 and transforming growth factor-beta 1 promote breast tumor cell invasion through up-regulation of the plasminogen/plasmin system
-
discussion 499-500
-
Albo, D., Berger, D.H., Wang, T.N., Hu, X., Rothman, V. and Tuszynski, G.P. (1997) Thrombospondin-1 and transforming growth factor-beta 1 promote breast tumor cell invasion through up-regulation of the plasminogen/plasmin system. Surgery 122:493-499discussion 499-500.
-
(1997)
Surgery
, vol.122
, pp. 493-499
-
-
Albo, D.1
Berger, D.H.2
Wang, T.N.3
Hu, X.4
Rothman, V.5
Tuszynski, G.P.6
-
3
-
-
0033981473
-
The plasminogen activation system in tumor growth, invasion, and metastasis
-
Andreasen, P.A., Egelund, R. and Petersen, H.H. (2000) The plasminogen activation system in tumor growth, invasion, and metastasis. Cell Mol Life Sci 57:25-40.
-
(2000)
Cell Mol Life Sci
, vol.57
, pp. 25-40
-
-
Andreasen, P.A.1
Egelund, R.2
Petersen, H.H.3
-
4
-
-
0037196163
-
The integrin alphaVbeta6 binds and activates latent TGFβ3
-
Annes, J.P., Rifkin, D.B. and Munger, J.S. (2002) The integrin alphaVbeta6 binds and activates latent TGFβ3. FEBS Lett 511:65-68.
-
(2002)
FEBS Lett
, vol.511
, pp. 65-68
-
-
Annes, J.P.1
Rifkin, D.B.2
Munger, J.S.3
-
5
-
-
0001505189
-
An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytes
-
Antonelli-Orlidge, A., Saunders, K.B., Smith, S.R. and D'Amore, P.A. (1989) An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytes. Proc Natl Acad Sci U S A 86:4544-4548.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 4544-4548
-
-
Antonelli-Orlidge, A.1
Saunders, K.B.2
Smith, S.R.3
D'Amore, P.A.4
-
6
-
-
0029091325
-
Thrombospondin and transforming growth factor-β1 increase expression of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in human MDA-MB-231 breast cancer cells
-
Arnoletti, J.P., Albo, D., Granick, M.S., Solomon, M.P., Castiglioni, A., Rothman, V.L. and Tuszynski, G.P. (1995) Thrombospondin and transforming growth factor-β1 increase expression of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in human MDA-MB-231 breast cancer cells. Cancer 76:998-1005.
-
(1995)
Cancer
, vol.76
, pp. 998-1005
-
-
Arnoletti, J.P.1
Albo, D.2
Granick, M.S.3
Solomon, M.P.4
Castiglioni, A.5
Rothman, V.L.6
Tuszynski, G.P.7
-
7
-
-
0027293946
-
Radiation-induced transforming growth factor β and subsequent extracellular matrix reorganization in murine mammary gland
-
Barcellos-Hoff, M.H. (1993) Radiation-induced transforming growth factor β and subsequent extracellular matrix reorganization in murine mammary gland. Cancer Res 53:3880-3886.
-
(1993)
Cancer Res
, vol.53
, pp. 3880-3886
-
-
Barcellos-Hoff, M.H.1
-
8
-
-
0029736871
-
Redox-mediated activation of latent transforming growth factor-β1
-
Barcellos-Hoff, M.H. and Dix, T.A. (1996) Redox-mediated activation of latent transforming growth factor-β1. Mol Endocrinol 10:1077-1083.
-
(1996)
Mol Endocrinol
, vol.10
, pp. 1077-1083
-
-
Barcellos-Hoff, M.H.1
Dix, T.A.2
-
9
-
-
0035890359
-
Transforming growth factor-β1 increases survival of human melanoma through stroma remodeling
-
Berking, C., Takemoto, R., Schaider, H., Showe, L., Satyamoorthy, K., Robbins, P. and Herlyn, M. (2001) Transforming growth factor-β1 increases survival of human melanoma through stroma remodeling. Cancer Res 61:8306-8316.
-
(2001)
Cancer Res
, vol.61
, pp. 8306-8316
-
-
Berking, C.1
Takemoto, R.2
Schaider, H.3
Showe, L.4
Satyamoorthy, K.5
Robbins, P.6
Herlyn, M.7
-
10
-
-
0035861541
-
Integrin beta 1 signaling is necessary for transforming growth factor-beta activation of p38MAPK and epithelial plasticity
-
Bhowmick, N.A., Zent, R., Ghiassi, M., McDonnell, M. and Moses, H.L. (2001) Integrin beta 1 signaling is necessary for transforming growth factor-beta activation of p38MAPK and epithelial plasticity. J Biol Chem 276:46707-46713.
-
(2001)
J Biol Chem
, vol.276
, pp. 46707-46713
-
-
Bhowmick, N.A.1
Zent, R.2
Ghiassi, M.3
McDonnell, M.4
Moses, H.L.5
-
11
-
-
0029034384
-
Mediation of glucocorticoid receptor function by the activation of latent transforming growth factor β1 in MG-63 human osteosarcoma cells
-
Boulanger, J., Reyes-Moreno, C. and Koutsilieris, M. (1995) Mediation of glucocorticoid receptor function by the activation of latent transforming growth factor β1 in MG-63 human osteosarcoma cells. Int J Cancer 61:692-697.
-
(1995)
Int J Cancer
, vol.61
, pp. 692-697
-
-
Boulanger, J.1
Reyes-Moreno, C.2
Koutsilieris, M.3
-
12
-
-
0028978232
-
Expression of the beta 6 integrin subunit in development, neoplasia and tissue repair suggests a role in epithelial remodeling
-
Breuss, J.M., Gallo, J., DeLisser, H.M., Klimanskaya, I.V., Folkesson, H.G., Pittet, J.F., Nishimura, S.L., Aldape, K., Landers, D.V., Carpenter, W., et, al. (1995) Expression of the beta 6 integrin subunit in development, neoplasia and tissue repair suggests a role in epithelial remodeling. J Cell Sci 108:2241-2251.
-
(1995)
J Cell Sci
, vol.108
, pp. 2241-2251
-
-
Breuss, J.M.1
Gallo, J.2
DeLisser, H.M.3
Klimanskaya, I.V.4
Folkesson, H.G.5
Pittet, J.F.6
Nishimura, S.L.7
Aldape, K.8
Landers, D.V.9
Carpenter, W.10
-
13
-
-
0024994691
-
Physiochemical activation of recombinant latent transforming growth factor-beta's 1, 2, and 3
-
Brown, P.D., Wakefield, L.M., Levinson, A.D. and Sporn, M.B. (1990) Physiochemical activation of recombinant latent transforming growth factor-beta's 1, 2, and 3. Growth Factors 3.35-43.
-
(1990)
Growth Factors
, vol.3
, pp. 35-43
-
-
Brown, P.D.1
Wakefield, L.M.2
Levinson, A.D.3
Sporn, M.B.4
-
14
-
-
7344248988
-
Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice
-
Bugge, T.H., Lund, L.R., Kombrinck, K.K., Nielsen, B.S., Holmback, K., Drew, A.F., Flick, M.J., Witte, D.P., Dano, K. and Degen, J.L. (1998) Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice. Oncogene 16:3097-3104.
-
(1998)
Oncogene
, vol.16
, pp. 3097-3104
-
-
Bugge, T.H.1
Lund, L.R.2
Kombrinck, K.K.3
Nielsen, B.S.4
Holmback, K.5
Drew, A.F.6
Flick, M.J.7
Witte, D.P.8
Dano, K.9
Degen, J.L.10
-
15
-
-
0034670372
-
A role for the integrin alphavbeta8 in the negative regulation of epithelial cell growth
-
Cambier, S., Mu, D.Z., O'Connell, D., Boylen, K., Travis, W., Liu, W.H., Broaddus, V.C. and Nishimura, S.L. (2000) A role for the integrin alphavbeta8 in the negative regulation of epithelial cell growth. Cancer Res 60:7084-7093.
-
(2000)
Cancer Res
, vol.60
, pp. 7084-7093
-
-
Cambier, S.1
Mu, D.Z.2
O'Connell, D.3
Boylen, K.4
Travis, W.5
Liu, W.H.6
Broaddus, V.C.7
Nishimura, S.L.8
-
16
-
-
12344320716
-
Thrombospondin-1 is a major activator of TGF-β1 in vivo
-
Crawford, S.E., Stellmach, V., Murphy-Ullrich, J.E., Ribeiro, S.M., Lawler, J., Hynes, R.O., Boivin, G.P. and Bouck, N. (1998) Thrombospondin-1 is a major activator of TGF-β1 in vivo. Cell 93:1159-1170.
-
(1998)
Cell
, vol.93
, pp. 1159-1170
-
-
Crawford, S.E.1
Stellmach, V.2
Murphy-Ullrich, J.E.3
Ribeiro, S.M.4
Lawler, J.5
Hynes, R.O.6
Boivin, G.P.7
Bouck, N.8
-
17
-
-
0026059613
-
Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor
-
Dennis, P.A. and Rifkin, D.B. (1991) Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor. Proc Natl Acad Sci U S A 88:580-584.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 580-584
-
-
Dennis, P.A.1
Rifkin, D.B.2
-
18
-
-
0034785348
-
TGF-β signaling in tumor suppression and cancer progression
-
Derynck, R., Akhurst, R.J. and Balmain, A. (2001) TGF-β signaling in tumor suppression and cancer progression. Nat Genet 29:117-129.
-
(2001)
Nat Genet
, vol.29
, pp. 117-129
-
-
Derynck, R.1
Akhurst, R.J.2
Balmain, A.3
-
19
-
-
0032870022
-
Genetic and epigenetic contributions to colorectal cancer
-
Dumont, N. (1999) Genetic and epigenetic contributions to colorectal cancer. APMIS 107:711-722.
-
(1999)
APMIS
, vol.107
, pp. 711-722
-
-
Dumont, N.1
-
20
-
-
0034468039
-
Transforming growth factor-beta and breast cancer: Tumor promoting effects of transforming growth factor-beta
-
Dumont, N. and Arteaga, C.L. (2000) Transforming growth factor-beta and breast cancer: Tumor promoting effects of transforming growth factor-beta. Breast Cancer Res 2:125-132.
-
(2000)
Breast Cancer Res
, vol.2
, pp. 125-132
-
-
Dumont, N.1
Arteaga, C.L.2
-
21
-
-
0027320003
-
Cell surface CD44-related chondroitin sulfate proteoglycan is required for transforming growth factor-β-stimulated mouse melanoma cell motility and invasive behavior on type I collagen
-
Faassen, A.E., Mooradian, D.L., Tranquillo, R.T., Dickinson, R.B., Letourneau, P.C., Oegema, T.R. and McCarthy, J.B. (1993) Cell surface CD44-related chondroitin sulfate proteoglycan is required for transforming growth factor-β-stimulated mouse melanoma cell motility and invasive behavior on type I collagen. J Cell Sci 105:501-511.
-
(1993)
J Cell Sci
, vol.105
, pp. 501-511
-
-
Faassen, A.E.1
Mooradian, D.L.2
Tranquillo, R.T.3
Dickinson, R.B.4
Letourneau, P.C.5
Oegema, T.R.6
McCarthy, J.B.7
-
22
-
-
0032473479
-
Transforming growth factor-β1 enhances the invasiveness of human MDA-MB-231 breast cancer cells by up-regulating urokinase activity
-
Farina, A.R., Coppa, A., Tiberio, A., Tacconelli, A., Turco, A., Colletta, G., Gulino, A. and Mackay, A.R. (1998) Transforming growth factor-β1 enhances the invasiveness of human MDA-MB-231 breast cancer cells by up-regulating urokinase activity. Int J Cancer 75:721-730.
-
(1998)
Int J Cancer
, vol.75
, pp. 721-730
-
-
Farina, A.R.1
Coppa, A.2
Tiberio, A.3
Tacconelli, A.4
Turco, A.5
Colletta, G.6
Gulino, A.7
Mackay, A.R.8
-
23
-
-
0033621749
-
Osteoblast-derived TGFbeta-1 modulates matrix degrading protease expression and activity in prostate cancer cells
-
Festuccia, C., Angelucci, A., Gravina, G.L., Villanova, I.I., Teti, A., Albini, A. and Bologna, M. (2000) Osteoblast-derived TGFbeta-1 modulates matrix degrading protease expression and activity in prostate cancer cells. Int J Cancer 85:407-415.
-
(2000)
Int J Cancer
, vol.85
, pp. 407-415
-
-
Festuccia, C.1
Angelucci, A.2
Gravina, G.L.3
Villanova, I.I.4
Teti, A.5
Albini, A.6
Bologna, M.7
-
24
-
-
0031941038
-
Enhanced expression of TGF-βs and their receptors in human acute pancreatitis
-
Friess, H., Lu, Z., Riesle, E., Uhl, W., Brundler, A.M., Horvath, L., Gold, L.I., Korc, M. and Buchler, M.W. (1998) Enhanced expression of TGF-βs and their receptors in human acute pancreatitis. Ann Surg 227:95-104.
-
(1998)
Ann Surg
, vol.227
, pp. 95-104
-
-
Friess, H.1
Lu, Z.2
Riesle, E.3
Uhl, W.4
Brundler, A.M.5
Horvath, L.6
Gold, L.I.7
Korc, M.8
Buchler, M.W.9
-
25
-
-
0033593025
-
Defects in transforming growth factor-beta signaling cooperate with a Ras oncogene to cause rapid aneuploidy and malignant transformation of mouse keratinocytes
-
Glick, A., Popescu, N., Alexander, V., Ueno, H., Bottinger, E. and Yuspa, S.H. (1999) Defects in transforming growth factor-beta signaling cooperate with a Ras oncogene to cause rapid aneuploidy and malignant transformation of mouse keratinocytes. Proc Natl Acad Sci U S A 96:14949-14954.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 14949-14954
-
-
Glick, A.1
Popescu, N.2
Alexander, V.3
Ueno, H.4
Bottinger, E.5
Yuspa, S.H.6
-
26
-
-
0024755673
-
Retinoic acid induces transforming growth factor-β2 in cultured keratinocytes and mouse epidermis
-
Glick, A.B., Flanders, K.C., Danielpour, D., Yuspa, S.H. and Sporn, M.B. (1989) Retinoic acid induces transforming growth factor-β2 in cultured keratinocytes and mouse epidermis. Cell Regul 1:87-97.
-
(1989)
Cell Regul
, vol.1
, pp. 87-97
-
-
Glick, A.B.1
Flanders, K.C.2
Danielpour, D.3
Yuspa, S.H.4
Sporn, M.B.5
-
27
-
-
0029784067
-
Transforming growth factor beta 1 suppresses genomic instability independent of a G1 arrest p53, Rb
-
Glick, A.B., Weinberg, W.C., Wu, I.H., Quan, W. and Yuspa, S.H. (1996) Transforming growth factor beta 1 suppresses genomic instability independent of a G1 arrest p53, Rb. Cancer Res 56:3645-3650.
-
(1996)
Cancer Res
, vol.56
, pp. 3645-3650
-
-
Glick, A.B.1
Weinberg, W.C.2
Wu, I.H.3
Quan, W.4
Yuspa, S.H.5
-
28
-
-
0344026339
-
M6P/IGFII-receptor complexes urokinase receptor and plasminogen for activation of transforming growth factor-betal
-
Godar, S., Horejsi, V., Weidle, U.H., Binder, B.R., Hansmann, C. and Stockinger, H. (1999) M6P/IGFII-receptor complexes urokinase receptor and plasminogen for activation of transforming growth factor-betal. Eur J Immunol 29:1004-1013.
-
(1999)
Eur J Immunol
, vol.29
, pp. 1004-1013
-
-
Godar, S.1
Horejsi, V.2
Weidle, U.H.3
Binder, B.R.4
Hansmann, C.5
Stockinger, H.6
-
29
-
-
0031927686
-
Dominant-negative interference of the transforming growth factor β type II receptor in mammary gland epithelium results in alveolar hyperplasia and differentiation in virgin mice
-
Gorska, A.E., Joseph, H., Derynck, R., Moses, H.L. and Serra, R. (1998) Dominant-negative interference of the transforming growth factor β type II receptor in mammary gland epithelium results in alveolar hyperplasia and differentiation in virgin mice. Cell Growth Differ 9:229-238.
-
(1998)
Cell Growth Differ
, vol.9
, pp. 229-238
-
-
Gorska, A.E.1
Joseph, H.2
Derynck, R.3
Moses, H.L.4
Serra, R.5
-
30
-
-
0037007226
-
Balancing the activation state of the endothelium via two distinct TGF-β type I receptors
-
Goumans, M.J., Valdimarsdottir, G., Itoh, S., Rosendahl, A., Sideras, P. and ten Dijke, P. (2002) Balancing the activation state of the endothelium via two distinct TGF-β type I receptors. EMBO J 21:1743-1753.
-
(2002)
EMBO J
, vol.21
, pp. 1743-1753
-
-
Goumans, M.J.1
Valdimarsdottir, G.2
Itoh, S.3
Rosendahl, A.4
Sideras, P.5
Ten Dijke, P.6
-
31
-
-
0036407230
-
Genetic and epigenetic alterations in colon cancer
-
Grady, W.M. and Markowitz, S.D. (2002) Genetic and Epigenetic Alterations in Colon Cancer. Annu Rev Genomics Hum Genet 3:101-128.
-
(2002)
Annu Rev Genomics Hum Genet
, vol.3
, pp. 101-128
-
-
Grady, W.M.1
Markowitz, S.D.2
-
32
-
-
0030593038
-
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
Hahn, S.A., Schutte, M., Hoque, A.T., Moskaluk, C.A., da Costa, L.T., Rozenblum, E., Weinstein, C.L., Fischer, A., Yeo, C.J., Hruban, R.H. and Kern, S.E. (1996) DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 271:350-353.
-
(1996)
Science
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.T.3
Moskaluk, C.A.4
Da Costa, L.T.5
Rozenblum, E.6
Weinstein, C.L.7
Fischer, A.8
Yeo, C.J.9
Hruban, R.H.10
Kern, S.E.11
-
33
-
-
0034987333
-
Overexpression of latent transforming growth factor-beta 1 (TGF-beta 1) binding protein 1 (LTBP-1) in association with TGF-beta 1 in ovarian carcinoma
-
Higashi, T., Sasagawa, T., Inoue, M., Oka, R., Shuangying, L. and Saijoh, K. (2001) Overexpression of latent transforming growth factor-beta 1 (TGF-beta 1) binding protein 1 (LTBP-1) in association with TGF-beta 1 in ovarian carcinoma. Jpn J Cancer Res 92:506-515.
-
(2001)
Jpn J Cancer Res
, vol.92
, pp. 506-515
-
-
Higashi, T.1
Sasagawa, T.2
Inoue, M.3
Oka, R.4
Shuangying, L.5
Saijoh, K.6
-
34
-
-
0033545299
-
Cyclosporine induces cancer progression by a cell-autonomous mechanism
-
Hojo, M., Morimoto, T., Maluccio, M., Asano, T., Morimoto, K., Lagman, M., Shimbo, T. and Suthanthiran, M. (1999) Cyclosporine induces cancer progression by a cell-autonomous mechanism. Nature 397:530-534.
-
(1999)
Nature
, vol.397
, pp. 530-534
-
-
Hojo, M.1
Morimoto, T.2
Maluccio, M.3
Asano, T.4
Morimoto, K.5
Lagman, M.6
Shimbo, T.7
Suthanthiran, M.8
-
35
-
-
0026770377
-
Integrins: Versatility, modulation, and signaling in cell adhesion
-
Hynes, R.O. (1992) Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69:11-25.
-
(1992)
Cell
, vol.69
, pp. 11-25
-
-
Hynes, R.O.1
-
36
-
-
0028952342
-
Positive correlation of plasma transforming growth factor-β1 levels with tumor vascularity in hepatocellular carcinoma
-
Ito, N., Kawata, S., Tamura, S., Shirai, Y., Kiso, S., Tsushima, H. and Matsuzawa, Y. (1995) Positive correlation of plasma transforming growth factor-β1 levels with tumor vascularity in hepatocellular carcinoma. Cancer Lett 89:45-48.
-
(1995)
Cancer Lett
, vol.89
, pp. 45-48
-
-
Ito, N.1
Kawata, S.2
Tamura, S.3
Shirai, Y.4
Kiso, S.5
Tsushima, H.6
Matsuzawa, Y.7
-
37
-
-
0032882539
-
Autocrine TGF-β-regulated expression of adhesion receptors and integrin-linked kinase in HT-144 melanoma cells correlates with their metastatic phenotype
-
Janji, B., Melchior, C., Gouon, V., Vallar, L. and Kieffer, N. (1999) Autocrine TGF-β-regulated expression of adhesion receptors and integrin-linked kinase in HT-144 melanoma cells correlates with their metastatic phenotype. Int J Cancer 83:255-262.
-
(1999)
Int J Cancer
, vol.83
, pp. 255-262
-
-
Janji, B.1
Melchior, C.2
Gouon, V.3
Vallar, L.4
Kieffer, N.5
-
38
-
-
0024360471
-
Acidic cellular environments: Activation of latent TGF-β and sensitization of cellular responses to TGF-β and EGF
-
Jullien, P., Berg, T.M. and Lawrence, D.A. (1989) Acidic cellular environments: activation of latent TGF-β and sensitization of cellular responses to TGF-β and EGF. Int J Cancer 43:886-891.
-
(1989)
Int J Cancer
, vol.43
, pp. 886-891
-
-
Jullien, P.1
Berg, T.M.2
Lawrence, D.A.3
-
39
-
-
0035914302
-
Induction of angiogenesis by expression of soluble type II transforming growth factor-beta receptor in mouse hepatoma
-
Kim, K.Y., Jeong, S.Y.; Won, J., Ryu, P.D. and Nam, M.J. (2001) Induction of angiogenesis by expression of soluble type II transforming growth factor-beta receptor in mouse hepatoma. J Biol Chem 276:38781-38786.
-
(2001)
J Biol Chem
, vol.276
, pp. 38781-38786
-
-
Kim, K.Y.1
Jeong, S.Y.2
Won, J.3
Ryu, P.D.4
Nam, M.J.5
-
40
-
-
0031050659
-
The regulation of expression of integrin receptors
-
Kim, L.T. and Yamada, K.M. (1997) The regulation of expression of integrin receptors. Proc Soc Exp Biol Med 214:123-131.
-
(1997)
Proc Soc Exp Biol Med
, vol.214
, pp. 123-131
-
-
Kim, L.T.1
Yamada, K.M.2
-
41
-
-
0034027480
-
Molecular mechanisms of inactivation of TGF-β receptors during carcinogenesis
-
Kim, S.J., Im, Y.H., Markowitz, S.D. and Bang, Y.J. (2000) Molecular mechanisms of inactivation of TGF-β receptors during carcinogenesis. Cytokine Growth Factor Rev 11:159-168.
-
(2000)
Cytokine Growth Factor Rev
, vol.11
, pp. 159-168
-
-
Kim, S.J.1
Im, Y.H.2
Markowitz, S.D.3
Bang, Y.J.4
-
42
-
-
0023625418
-
Evidence that transforming growth factor-β is a hormonally regulated negative growth factor in human breast cancer cells
-
Knabbe, C., Lippman, M.E., Wakefield, L.M., Flanders, K.C., Kasid, A., Derynck, R. and Dickson, R.B. (1987) Evidence that transforming growth factor-β is a hormonally regulated negative growth factor in human breast cancer cells. Cell 48:417-428.
-
(1987)
Cell
, vol.48
, pp. 417-428
-
-
Knabbe, C.1
Lippman, M.E.2
Wakefield, L.M.3
Flanders, K.C.4
Kasid, A.5
Derynck, R.6
Dickson, R.B.7
-
43
-
-
0027340165
-
Vitamin D3 and calcipotriol enhance the secretion of transforming growth factor-β1 and -β2 in cultured murine keratinocytes
-
Koli, K. and Keski-Oja, J. (1993) Vitamin D3 and calcipotriol enhance the secretion of transforming growth factor-β1 and -β2 in cultured murine keratinocytes. Growth Factors 8:153-163.
-
(1993)
Growth Factors
, vol.8
, pp. 153-163
-
-
Koli, K.1
Keski-Oja, J.2
-
44
-
-
0035865279
-
Latency, activation, and binding proteins of TGF-β
-
Koli, K., Saharinen, J., Hyytiainen, M., Penttinen, C. and Keski-Oja, J. (2001) Latency, activation, and binding proteins of TGF-β. Microsc Res Tech 52:354-362.
-
(2001)
Microsc Res Tech
, vol.52
, pp. 354-362
-
-
Koli, K.1
Saharinen, J.2
Hyytiainen, M.3
Penttinen, C.4
Keski-Oja, J.5
-
45
-
-
0036362236
-
Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth
-
Lawler, J. (2002) Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth. J Cell Mol Med 6:1-12.
-
(2002)
J Cell Mol Med
, vol.6
, pp. 1-12
-
-
Lawler, J.1
-
46
-
-
0034575168
-
TGFbetal stimulates the secretion of matrix metalloproteinase 2 (MMP2) and the invasive behavior in human ovarian cancer cells, which is suppressed by MMP inhibitor BB3103
-
Lin, S.W., Lee, M.T., Ke, F.C., Lee, P.P., Huang, C.J., Ip, M.M., Chen, L. and Hwang, J.J. (2000) TGFbetal stimulates the secretion of matrix metalloproteinase 2 (MMP2) and the invasive behavior in human ovarian cancer cells, which is suppressed by MMP inhibitor BB3103. Clin Exp Metastasis 18:493-499.
-
(2000)
Clin Exp Metastasis
, vol.18
, pp. 493-499
-
-
Lin, S.W.1
Lee, M.T.2
Ke, F.C.3
Lee, P.P.4
Huang, C.J.5
Ip, M.M.6
Chen, L.7
Hwang, J.J.8
-
47
-
-
0025215307
-
Mechanism of activation of latent recombinant transforming growth factor β1 by plasmin
-
Lyons, R.M., Gentry, L.E., Purchio, A.F. and Moses, H.L. (1990) Mechanism of activation of latent recombinant transforming growth factor β1 by plasmin. J Cell Biol 110:1361-1367.
-
(1990)
J Cell Biol
, vol.110
, pp. 1361-1367
-
-
Lyons, R.M.1
Gentry, L.E.2
Purchio, A.F.3
Moses, H.L.4
-
48
-
-
0023916551
-
Proteolytic activation of latent transforming growth factor-β from fibroblast-conditioned medium
-
Lyons, R.M., Keski-Oja, J. and Moses, H.L. (1988) Proteolytic activation of latent transforming growth factor-β from fibroblast-conditioned medium. J Cell Biol 106:1659-1665.
-
(1988)
J Cell Biol
, vol.106
, pp. 1659-1665
-
-
Lyons, R.M.1
Keski-Oja, J.2
Moses, H.L.3
-
49
-
-
17544372403
-
Transforming growth factor beta 1 down-regulates vascular endothelial growth factor receptor 2/flk-1 expression in vascular endothelial cells
-
Mandriota, S.J., Menoud, P.A. and Pepper, M.S. (1996) Transforming growth factor beta 1 down-regulates vascular endothelial growth factor receptor 2/flk-1 expression in vascular endothelial cells. J Biol Chem 271:11500-11505.
-
(1996)
J Biol Chem
, vol.271
, pp. 11500-11505
-
-
Mandriota, S.J.1
Menoud, P.A.2
Pepper, M.S.3
-
50
-
-
0030183051
-
Tumor suppressor activity of the TGF-β pathway in human cancers
-
Markowitz, S.D. and Roberts, A.B. (1996) Tumor suppressor activity of the TGF-β pathway in human cancers. Cytokine Growth Factor Rev 7:93-102.
-
(1996)
Cytokine Growth Factor Rev
, vol.7
, pp. 93-102
-
-
Markowitz, S.D.1
Roberts, A.B.2
-
51
-
-
0025222517
-
The transforming growth factor-β family
-
Massagué, J. (1990) The transforming growth factor-β family. Annu Rev Cell Biol 6:597-641.
-
(1990)
Annu Rev Cell Biol
, vol.6
, pp. 597-641
-
-
Massagué, J.1
-
52
-
-
0034176764
-
Matrix metalloproteinases: Multifunctional contributors to tumor progression
-
McCawley, L.J. and Matrisian, L.M. (2000) Matrix metalloproteinases: multifunctional contributors to tumor progression. Mol Med Today 6:149-156.
-
(2000)
Mol Med Today
, vol.6
, pp. 149-156
-
-
McCawley, L.J.1
Matrisian, L.M.2
-
53
-
-
0035503689
-
Thrombospondin-1 type 1 repeat recombinant proteins inhibit tumor growth through transforming growth factor-β-dependent and -independent mechanisms
-
Miao, W.M., Seng, W.L., Duquette, M., Lawler, P., Laus, C. and Lawler, J. (2001) Thrombospondin-1 type 1 repeat recombinant proteins inhibit tumor growth through transforming growth factor-β-dependent and -independent mechanisms. Cancer Res 61:7830-7839.
-
(2001)
Cancer Res
, vol.61
, pp. 7830-7839
-
-
Miao, W.M.1
Seng, W.L.2
Duquette, M.3
Lawler, P.4
Laus, C.5
Lawler, J.6
-
54
-
-
0035895893
-
Transforming growth factor-beta 1-mediated inhibition of the flk-1/KDR gene is mediated by a 5′-untranslated region palindromic GATA site
-
Minami, T., Rosenberg, R.D. and Aird, W.C. (2001) Transforming growth factor-beta 1-mediated inhibition of the flk-1/KDR gene is mediated by a 5′-untranslated region palindromic GATA site. J Biol Chem 276:5395-5402.
-
(2001)
J Biol Chem
, vol.276
, pp. 5395-5402
-
-
Minami, T.1
Rosenberg, R.D.2
Aird, W.C.3
-
55
-
-
0024539847
-
Role for carbohydrate structures in TGF-β1 latency
-
Miyazono, K. and Heldin, C.H. (1989) Role for carbohydrate structures in TGF-β1 latency. Nature 338:158-160.
-
(1989)
Nature
, vol.338
, pp. 158-160
-
-
Miyazono, K.1
Heldin, C.H.2
-
56
-
-
0027466618
-
Transforming growth factor-β: Latent forms, binding proteins and receptors
-
Miyazono, K., Ichijo, H. and Heldin, C.H. (1993) Transforming growth factor-β: latent forms, binding proteins and receptors. Growth Factors 8:11-22.
-
(1993)
Growth Factors
, vol.8
, pp. 11-22
-
-
Miyazono, K.1
Ichijo, H.2
Heldin, C.H.3
-
57
-
-
0030823299
-
In situ expression of transforming growth factor β is associated with melanoma progression and correlates with Ki67, HLA-DR and beta 3 integrin expression
-
Moretti, S., Pinzi, C., Berti, E., Spallanzani, A., Chiarugi, A., Boddi, V., Reali, U.M. and Giannotti, B. (1997) In situ expression of transforming growth factor β is associated with melanoma progression and correlates with Ki67, HLA-DR and beta 3 integrin expression. Melanoma Res 7:313-321.
-
(1997)
Melanoma Res
, vol.7
, pp. 313-321
-
-
Moretti, S.1
Pinzi, C.2
Berti, E.3
Spallanzani, A.4
Chiarugi, A.5
Boddi, V.6
Reali, U.M.7
Giannotti, B.8
-
58
-
-
0025104027
-
TGF-beta stimulation and inhibition of cell proliferation: New mechanistic insights
-
Moses, H.L., Yang, E.Y. and Pietenpol, J.A. (1990) TGF-beta stimulation and inhibition of cell proliferation: new mechanistic insights. Cell 63:245-247.
-
(1990)
Cell
, vol.63
, pp. 245-247
-
-
Moses, H.L.1
Yang, E.Y.2
Pietenpol, J.A.3
-
59
-
-
0037192933
-
The integrin alphavbeta8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-β1
-
Mu, D., Cambier, S., Fjellbirkeland, L., Baron, J.L., Munger, J.S., Kawakatsu, H., Sheppard, D., Broaddus, V.C. and Nishimura, S.L. (2002) The integrin alphavbeta8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-β1. J Cell Biol 157:493-507.
-
(2002)
J Cell Biol
, vol.157
, pp. 493-507
-
-
Mu, D.1
Cambier, S.2
Fjellbirkeland, L.3
Baron, J.L.4
Munger, J.S.5
Kawakatsu, H.6
Sheppard, D.7
Broaddus, V.C.8
Nishimura, S.L.9
-
60
-
-
0031670654
-
Interactions between growth factors and integrins: Latent forms of transforming growth factor-β are ligands for the integrin alphavbeta1
-
Munger, J.S., Harpel, J.G., Giancotti, F.G. and Rifkin, D.B. (1998) Interactions between growth factors and integrins: latent forms of transforming growth factor-β are ligands for the integrin alphavbeta1. Mol Biol Cell 9:2627-2638.
-
(1998)
Mol Biol Cell
, vol.9
, pp. 2627-2638
-
-
Munger, J.S.1
Harpel, J.G.2
Giancotti, F.G.3
Rifkin, D.B.4
-
61
-
-
0033524949
-
The integrin alphav beta 6 binds and activates latent TGFβ1: A mechanism for regulating pulmonary inflammation and fibrosis
-
Munger, J.S., Huang, X., Kawakatsu, H., Griffiths, M.J., Dalton, S.L., Wu, J., Pittet, J.F., Kaminski, N., Garat, C., Matthay, M.A., Rifkin, D.B. and Sheppard, D. (1999) The integrin alphav beta 6 binds and activates latent TGFβ1: a mechanism for regulating pulmonary inflammation and fibrosis. Cell 96:319-328.
-
(1999)
Cell
, vol.96
, pp. 319-328
-
-
Munger, J.S.1
Huang, X.2
Kawakatsu, H.3
Griffiths, M.J.4
Dalton, S.L.5
Wu, J.6
Pittet, J.F.7
Kaminski, N.8
Garat, C.9
Matthay, M.A.10
Rifkin, D.B.11
Sheppard, D.12
-
62
-
-
0036086409
-
Blockade of TGF-β inhibits mammary tumor cell viability, migration, and metastases
-
Muraoka, R.S., Dumont, N., Ritter, C.A., Dugger, T.C., Brantley, D.M., Chen, J., Easterly, E., Roebuck, L.R., Ryan, S., Gotwals, P.J., Koteliansky, V. and Arteaga, C.L. (2002) Blockade of TGF-β inhibits mammary tumor cell viability, migration, and metastases. J Clin Invest 109:1551-1559.
-
(2002)
J Clin Invest
, vol.109
, pp. 1551-1559
-
-
Muraoka, R.S.1
Dumont, N.2
Ritter, C.A.3
Dugger, T.C.4
Brantley, D.M.5
Chen, J.6
Easterly, E.7
Roebuck, L.R.8
Ryan, S.9
Gotwals, P.J.10
Koteliansky, V.11
Arteaga, C.L.12
-
63
-
-
0032571765
-
Synaptic and glial localization of the integrin alphavbeta8 in mouse and rat brain
-
Nishimura, S.L., Boylen, K.P., Einheber, S., Milner, T.A., Ramos, D.M. and Pytela, R. (1998) Synaptic and glial localization of the integrin alphavbeta8 in mouse and rat brain. Brain Res 791:271-282.
-
(1998)
Brain Res
, vol.791
, pp. 271-282
-
-
Nishimura, S.L.1
Boylen, K.P.2
Einheber, S.3
Milner, T.A.4
Ramos, D.M.5
Pytela, R.6
-
64
-
-
0028984569
-
Characterization of latent TGF-beta activation by murine peritoneal macrophages
-
Nunes, I., Shapiro, R.L. and Rifkin, D.B. (1995) Characterization of latent TGF-beta activation by murine peritoneal macrophages. J Immunol 155:1450-1459.
-
(1995)
J Immunol
, vol.155
, pp. 1450-1459
-
-
Nunes, I.1
Shapiro, R.L.2
Rifkin, D.B.3
-
65
-
-
0032547895
-
TGFβ signaling is necessary for carcinoma cell invasiveness and metastasis
-
Oft, M., Heider, K.H. and Beug, H. (1998) TGFβ signaling is necessary for carcinoma cell invasiveness and metastasis. Curr Biol 8:1243-1252.
-
(1998)
Curr Biol
, vol.8
, pp. 1243-1252
-
-
Oft, M.1
Heider, K.H.2
Beug, H.3
-
66
-
-
0037138818
-
Up-regulation of thrombospondin-1 gene by epidermal growth factor and transforming growth factor beta in human cancer cells - Transcriptional activation and messenger RNA stabilization
-
Okamoto, M., Ono, M., Uchiumi, T., Ueno, H., Kohno, K., Sugimachi, K. and Kuwano, M. (2002) Up-regulation of thrombospondin-1 gene by epidermal growth factor and transforming growth factor beta in human cancer cells - transcriptional activation and messenger RNA stabilization. Biochim Biophys Acta 1574:24-34.
-
(2002)
Biochim Biophys Acta
, vol.1574
, pp. 24-34
-
-
Okamoto, M.1
Ono, M.2
Uchiumi, T.3
Ueno, H.4
Kohno, K.5
Sugimachi, K.6
Kuwano, M.7
-
67
-
-
0025866180
-
Transcriptional and post-transcriptional regulation of 72-kDa gelatinase/type IV collagenase by transforming growth factor-β1 in human fibroblasts. Comparisons with collagenase and tissue inhibitor of matrix metalloproteinase gene expression
-
Overall, C.M., Wrana, J.L. and Sodek, J. (1991) Transcriptional and post-transcriptional regulation of 72-kDa gelatinase/type IV collagenase by transforming growth factor-β1 in human fibroblasts. Comparisons with collagenase and tissue inhibitor of matrix metalloproteinase gene expression. J Biol Chem 266:14064-14071.
-
(1991)
J Biol Chem
, vol.266
, pp. 14064-14071
-
-
Overall, C.M.1
Wrana, J.L.2
Sodek, J.3
-
68
-
-
0031106404
-
Transforming growth factor-β: Vasculogenesis, angiogenesis, and vessel wall integrity
-
Pepper, M.S. (1997) Transforming growth factor-β: vasculogenesis, angiogenesis, and vessel wall integrity. Cytokine Growth Factor Rev 8:21-43.
-
(1997)
Cytokine Growth Factor Rev
, vol.8
, pp. 21-43
-
-
Pepper, M.S.1
-
69
-
-
0029010734
-
Mammary tumor suppression by transforming growth factor beta 1 transgene expression
-
Pierce, D.F. Jr, Gorska, A.E., Chytil, A., Meise, K.S., Page, D.L., Coffey, R.J. Jr and Moses, H.L. (1995) Mammary tumor suppression by transforming growth factor beta 1 transgene expression. Proc Natl Acad Sci U S A 92:4254-4258.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 4254-4258
-
-
Pierce D.F., Jr.1
Gorska, A.E.2
Chytil, A.3
Meise, K.S.4
Page, D.L.5
Coffey R.J., Jr.6
Moses, H.L.7
-
70
-
-
0027136742
-
Inhibition of mammary duct development but not alveolar outgrowth during pregnancy in transgenic mice expressing active TGF-beta 1
-
Pierce, D.F. Jr, Johnson, M.D., Matsui, Y., Robinson, S.D., Gold, L.I., Purchio, A.F., Daniel, C.W., Hogan, B.L. and Moses, H.L. (1993) Inhibition of mammary duct development but not alveolar outgrowth during pregnancy in transgenic mice expressing active TGF-beta 1. Genes Dev 7:2308-2317.
-
(1993)
Genes Dev
, vol.7
, pp. 2308-2317
-
-
Pierce D.F., Jr.1
Johnson, M.D.2
Matsui, Y.3
Robinson, S.D.4
Gold, L.I.5
Purchio, A.F.6
Daniel, C.W.7
Hogan, B.L.8
Moses, H.L.9
-
71
-
-
0031817391
-
Transforming growth factor β is essential for spindle cell conversion of mouse skin carcinoma in vivo: Implications for tumor invasion
-
Portella, G., Cumming, S.A., Liddell, J., Cui, W., Ireland, H., Akhurst, R.J. and Balmain, A. (1998) Transforming growth factor β is essential for spindle cell conversion of mouse skin carcinoma in vivo: implications for tumor invasion. Cell Growth Differ 9:393-404.
-
(1998)
Cell Growth Differ
, vol.9
, pp. 393-404
-
-
Portella, G.1
Cumming, S.A.2
Liddell, J.3
Cui, W.4
Ireland, H.5
Akhurst, R.J.6
Balmain, A.7
-
72
-
-
0035940429
-
Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor
-
Rodriguez-Manzaneque, J.C., Lane, T.F., Ortega, M.A., Hynes, R.O., Lawler, J. and Iruela-Arispe, M.L. (2001) Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor. Proc Natl Acad Sci U S A 98:12485-12490.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 12485-12490
-
-
Rodriguez-Manzaneque, J.C.1
Lane, T.F.2
Ortega, M.A.3
Hynes, R.O.4
Lawler, J.5
Iruela-Arispe, M.L.6
-
73
-
-
0034803035
-
Soluble type II transforming growth factor-beta (TGF-beta) receptor inhibits TGF-beta signaling in COLO-357 pancreatic cancer cells in vitro and attenuates tumor formation
-
Rowland-Goldsmith, M.A., Maruyama, H., Kusama, T., Ralli, S. and Korc, M. (2001) Soluble type II transforming growth factor-beta (TGF-beta) receptor inhibits TGF-beta signaling in COLO-357 pancreatic cancer cells in vitro and attenuates tumor formation. Clin Cancer Res 7:2931-2940.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 2931-2940
-
-
Rowland-Goldsmith, M.A.1
Maruyama, H.2
Kusama, T.3
Ralli, S.4
Korc, M.5
-
74
-
-
0026535245
-
Autocrine induction of tumor protease production and invasion by a metallothionein-regulated TGF-β1 (Ser223, 225)
-
Samuel, S.K., Hurta, R.A., Kondaiah, P., Khalil, N., Turley, E.A., Wright, J.A. and Greenberg, A.H. (1992) Autocrine induction of tumor protease production and invasion by a metallothionein-regulated TGF-β1 (Ser223, 225). EMBO J 11:1599-1605.
-
(1992)
EMBO J
, vol.11
, pp. 1599-1605
-
-
Samuel, S.K.1
Hurta, R.A.2
Kondaiah, P.3
Khalil, N.4
Turley, E.A.5
Wright, J.A.6
Greenberg, A.H.7
-
75
-
-
0024382711
-
Inhibition of endothelial cell movement by pericytes and smooth muscle cells: Activation of a latent transforming growth factor-β1-like molecule by plasmin during co-culture
-
Sato, Y. and Rifkin, D.B. (1989) Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-β1-like molecule by plasmin during co-culture. J Cell Biol 109:309-315.
-
(1989)
J Cell Biol
, vol.109
, pp. 309-315
-
-
Sato, Y.1
Rifkin, D.B.2
-
76
-
-
0027305971
-
Thrombospondin causes activation of latent transforming growth factor-β secreted by endothelial cells by a novel mechanism
-
Schultz-Cherry, S. and Murphy-Ullrich, J.E. (1993) Thrombospondin causes activation of latent transforming growth factor-β secreted by endothelial cells by a novel mechanism. J Cell Biol 122:923-932.
-
(1993)
J Cell Biol
, vol.122
, pp. 923-932
-
-
Schultz-Cherry, S.1
Murphy-Ullrich, J.E.2
-
77
-
-
0027967771
-
Thrombospondin binds and activates the small and large forms of latent transforming growth factor-β in a chemically defined system
-
Schultz-Cherry, S., Ribeiro, S., Gentry, L. and Murphy-Ullrich, J.E. (1994) Thrombospondin binds and activates the small and large forms of latent transforming growth factor-β in a chemically defined system. J Biol Chem 269:26775-26782.
-
(1994)
J Biol Chem
, vol.269
, pp. 26775-26782
-
-
Schultz-Cherry, S.1
Ribeiro, S.2
Gentry, L.3
Murphy-Ullrich, J.E.4
-
78
-
-
0036136943
-
Mechanisms of TGF-β-mediated apoptosis
-
Schuster, N. and Krieglstein, K. (2002) Mechanisms of TGF-β-mediated apoptosis. Cell Tissue Res 307:1-14.
-
(2002)
Cell Tissue Res
, vol.307
, pp. 1-14
-
-
Schuster, N.1
Krieglstein, K.2
-
79
-
-
9344223357
-
DPC4 gene in various tumor types
-
Schutte, M., Hruban, R.H., Hedrick, L., Cho, K.R., Nadasdy, G.M., Weinstein, C.L., Bova, G.S., Isaacs, W.B., Cairns, P., Nawroz, H., Sidransky, D., Casero, R.A. Jr, Meltzer, P.S., Hahn, S.A. and Kern, S.E. (1996) DPC4 gene in various tumor types. Cancer Res 56:2527-2530.
-
(1996)
Cancer Res
, vol.56
, pp. 2527-2530
-
-
Schutte, M.1
Hruban, R.H.2
Hedrick, L.3
Cho, K.R.4
Nadasdy, G.M.5
Weinstein, C.L.6
Bova, G.S.7
Isaacs, W.B.8
Cairns, P.9
Nawroz, H.10
Sidransky, D.11
Casero R.A., Jr.12
Meltzer, P.S.13
Hahn, S.A.14
Kern, S.E.15
-
80
-
-
0033587016
-
DPC4/SMAD4 mediated tumor suppression of colon carcinoma cells is associated with reduced urokinase expression
-
Schwarte-Waldhoff, I., Klein, S., Blass-Kampmann, S., Hintelmann, A., Eilert, C., Dreschers, S., Kalthoff, H., Hahn, S.A. and Schmiegel, W. (1999) DPC4/SMAD4 mediated tumor suppression of colon carcinoma cells is associated with reduced urokinase expression. Oncogene 18:3152-3158.
-
(1999)
Oncogene
, vol.18
, pp. 3152-3158
-
-
Schwarte-Waldhoff, I.1
Klein, S.2
Blass-Kampmann, S.3
Hintelmann, A.4
Eilert, C.5
Dreschers, S.6
Kalthoff, H.7
Hahn, S.A.8
Schmiegel, W.9
-
81
-
-
0030002175
-
Transforming growth factor β1 stimulates contrasting responses in metastatic versus primary mouse prostate cancer-derived cell lines in vitro
-
Sehgal, I., Baley, P.A. and Thompson, T.C. (1996) Transforming growth factor β1 stimulates contrasting responses in metastatic versus primary mouse prostate cancer-derived cell lines in vitro. Cancer Res 56:3359-3365.
-
(1996)
Cancer Res
, vol.56
, pp. 3359-3365
-
-
Sehgal, I.1
Baley, P.A.2
Thompson, T.C.3
-
82
-
-
0035196587
-
Transforming growth factor β enhances epithelial cell survival via Akt-dependent regulation of FKHRL1
-
Shin, I., Bakin, A.V., Rodeck, U., Brunet, A. and Arteaga, C.L. (2001) Transforming growth factor β enhances epithelial cell survival via Akt-dependent regulation of FKHRL1. Mol Biol Cell 12:3328-3339.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 3328-3339
-
-
Shin, I.1
Bakin, A.V.2
Rodeck, U.3
Brunet, A.4
Arteaga, C.L.5
-
83
-
-
0027976521
-
Latent transforming growth factor-β1 associates to fibroblast extracellular matrix via latent TGF-β binding protein
-
Taipale, J., Miyazono, K., Heldin, C.H. and Keski-Oja, J. (1994) Latent transforming growth factor-β1 associates to fibroblast extracellular matrix via latent TGF-β binding protein. J Cell Biol 124:171-181.
-
(1994)
J Cell Biol
, vol.124
, pp. 171-181
-
-
Taipale, J.1
Miyazono, K.2
Heldin, C.H.3
Keski-Oja, J.4
-
84
-
-
15844390729
-
Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers
-
Thiagalingam, S., Lengauer, C., Leach, F.S., Schutte, M., Hahn, S.A., Overhauser, J., Willson, J.K., Markowitz, S., Hamilton, S.R., Kern, S.E., Kinzler, K.W. and Vogelstein, B. (1996) Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers. Nat Genet 13:343-346.
-
(1996)
Nat Genet
, vol.13
, pp. 343-346
-
-
Thiagalingam, S.1
Lengauer, C.2
Leach, F.S.3
Schutte, M.4
Hahn, S.A.5
Overhauser, J.6
Willson, J.K.7
Markowitz, S.8
Hamilton, S.R.9
Kern, S.E.10
Kinzler, K.W.11
Vogelstein, B.12
-
85
-
-
0035354344
-
AlphaVbeta6 integrin promotes invasion of squamous carcinoma cells through up-regulation of matrix metalloproteinase-9
-
Thomas, G.J., Lewis, M.P., Hart, I.R., Marshall, J.F. and Speight, P.M. (2001) AlphaVbeta6 integrin promotes invasion of squamous carcinoma cells through up-regulation of matrix metalloproteinase-9. Int J Cancer 92:641-650.
-
(2001)
Int J Cancer
, vol.92
, pp. 641-650
-
-
Thomas, G.J.1
Lewis, M.P.2
Hart, I.R.3
Marshall, J.F.4
Speight, P.M.5
-
86
-
-
0026712153
-
Excessive production of transforming growth-factor β1 can play an important role in the development of tumorigenesis by its action for angiogenesis: Validity of neutralizing antibodies to block tumor growth
-
Ueki, N., Nakazato, M., Ohkawa, T., Ikeda, T, Amuro, Y., Hada, T and Higashino, K (1992) Excessive production of transforming growth-factor β1 can play an important role in the development of tumorigenesis by its action for angiogenesis: validity of neutralizing antibodies to block tumor growth. Biochim Biophys Acta 1137:189-196.
-
(1992)
Biochim Biophys Acta
, vol.1137
, pp. 189-196
-
-
Ueki, N.1
Nakazato, M.2
Ohkawa, T.3
Ikeda, T.4
Amuro, Y.5
Hada, T.6
Higashino, K.7
-
87
-
-
0036467496
-
TGF-β signaling: Positive and negative effects on tumorigenesis
-
Wakefield, L.M. and Roberts, A.B. (2002) TGF-β signaling: positive and negative effects on tumorigenesis. Curr Opin Genet Dev 12:22-29.
-
(2002)
Curr Opin Genet Dev
, vol.12
, pp. 22-29
-
-
Wakefield, L.M.1
Roberts, A.B.2
-
88
-
-
0033617339
-
Control of type II transforming growth factor-beta receptor expression by integrin ligation
-
Wang, D., Sun, L., Zborowska, E., Willson, J.K., Gong, J., Verraraghavan, J. and Brattain, M.G. (1999) Control of type II transforming growth factor-beta receptor expression by integrin ligation. J Biol Chem 274:12840-12847.
-
(1999)
J Biol Chem
, vol.274
, pp. 12840-12847
-
-
Wang, D.1
Sun, L.2
Zborowska, E.3
Willson, J.K.4
Gong, J.5
Verraraghavan, J.6
Brattain, M.G.7
-
89
-
-
0030740663
-
Deficient transforming growth factor-betal activation and excessive insulin-like growth factor II (IGFII) expression in IGFII receptor-mutant tumors
-
Wang, S., Souza, R.F., Kong, D., Yin, J., Smolinski, K.N., Zou, T.T., Frank, T., Young, J., Flanders, K.C., Sugimura, H., Abraham, J.M. and Meltzer, S.J. (1997) Deficient transforming growth factor-betal activation and excessive insulin-like growth factor II (IGFII) expression in IGFII receptor-mutant tumors. Cancer Res 57:2543-2546.
-
(1997)
Cancer Res
, vol.57
, pp. 2543-2546
-
-
Wang, S.1
Souza, R.F.2
Kong, D.3
Yin, J.4
Smolinski, K.N.5
Zou, T.T.6
Frank, T.7
Young, J.8
Flanders, K.C.9
Sugimura, H.10
Abraham, J.M.11
Meltzer, S.J.12
-
90
-
-
0035887461
-
Inducible expression of transforming growth factor betal in papillomas causes rapid metastasis
-
Weeks, B.H., He, W., Olson, K.L. and Wang, X.J. (2001) Inducible expression of transforming growth factor betal in papillomas causes rapid metastasis. Cancer Res 61:7435-7443.
-
(2001)
Cancer Res
, vol.61
, pp. 7435-7443
-
-
Weeks, B.H.1
He, W.2
Olson, K.L.3
Wang, X.J.4
-
91
-
-
0031928528
-
Transforming growth factor β1 is associated with angiogenesis, metastasis, and poor clinical outcome in prostate cancer
-
Wikstrom, P., Stattin, P., Franck-Lissbrant, I., Damber, J.E. and Bergh, A. (1998) Transforming growth factor β1 is associated with angiogenesis, metastasis, and poor clinical outcome in prostate cancer. Prostate 37:19-29.
-
(1998)
Prostate
, vol.37
, pp. 19-29
-
-
Wikstrom, P.1
Stattin, P.2
Franck-Lissbrant, I.3
Damber, J.E.4
Bergh, A.5
-
92
-
-
0032918414
-
TGF-β signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development
-
Yin, J.J., Selander, K., Chirgwin, J.M., Dallas, M., Grubbs, B.G., Wieser, R., Massagué, J., Mundy, G.R. and Guise, T.A. (1999) TGF-β signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development. J Clin Invest 103:197-206.
-
(1999)
J Clin Invest
, vol.103
, pp. 197-206
-
-
Yin, J.J.1
Selander, K.2
Chirgwin, J.M.3
Dallas, M.4
Grubbs, B.G.5
Wieser, R.6
Massagué, J.7
Mundy, G.R.8
Guise, T.A.9
-
93
-
-
0032926177
-
Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion
-
Yu, Q. and Stamenkovic, I. (1999) Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion. Genes Dev 13:35-48.
-
(1999)
Genes Dev
, vol.13
, pp. 35-48
-
-
Yu, Q.1
Stamenkovic, I.2
-
94
-
-
0034650486
-
Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-β and promotes tumor invasion and angiogenesis
-
Yu, Q. and Stamenkovic, I. (2000) Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-β and promotes tumor invasion and angiogenesis. Genes Dev 14:163-176.
-
(2000)
Genes Dev
, vol.14
, pp. 163-176
-
-
Yu, Q.1
Stamenkovic, I.2
-
95
-
-
0035810944
-
Genetic programs of epithelial cell plasticity directed by transforming growth factor-beta
-
Zavadil, J., Bitzer, M., Liang, D., Yang, Y.C., Massimi, A., Kneitz, S., Piek, E. and Bottinger, E.P. (2001) Genetic programs of epithelial cell plasticity directed by transforming growth factor-beta. Proc Natl Acad Sci U S A 98:6686-6691.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 6686-6691
-
-
Zavadil, J.1
Bitzer, M.2
Liang, D.3
Yang, Y.C.4
Massimi, A.5
Kneitz, S.6
Piek, E.7
Bottinger, E.P.8
|