Divergence of the feeding and thermogenic pathways influenced by NPY in the hypothalamic PVN of the rat

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 275, Issue 2 44-2, 1998, Pages

  Kotz, Catherine M ^a,b   Briggs, Jacqueline E ^a   Grace, Martha K ^b   Levine, Allen S ^a,b   Billington, Charles J ^a,b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Brown adipose tissue; Feeding behavior; Nucleus of the solitary tract; Opioids; Uncoupling protein

Indexed keywords

NEUROPEPTIDE Y;

ANIMAL EXPERIMENT; ARTICLE; BROWN ADIPOSE TISSUE; FEEDING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SOLITARY TRACT NUCLEUS; THALAMUS MIDLINE NUCLEUS;

EID: 0031846668     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1998.275.2.r471     Document Type: Article

References (16)

1. Akil, H., S. J. Watson, E. Young, M. E. Lewis, H. Khachaturian, and M. E. Walker. Endogenous opioids: biology and function. Annu. Rev. Neurosci. 7: 223-255, 1984.
2. Allen, J. M., and J. I. Koenig. Central and Peripheral Significance of Neuropeptide Y and Its Related Peptides. New York: The New York Academy of Sciences, 1990.
3. Barraco, I. R. A. Nucleus of the Solitary Tract. Boca Raton, FL: CRC, 1994.
4. Billington, C. J., J. E. Briggs, M. Grace, and A. S. Levine. Effects of intracerebroventricular injection of neuropeptide Y on energy metabolism. Am. J. Physiol. 260 (Regulatory Integrative Comp. Physiol. 29): R321-R327, 1991.
5. Billington, C. J., J. E. Briggs, S. Harker, M. Grace, and A. S. Levine. Neuropeptide Y in hypothalamic paraventricular nucleus: a center coordinating energy metabolism. Am. J. Physiol. 266 (Regulatory Integrative Comp. Physiol. 35): R1765-R1770, 1994.
6. Chang, C. L., Y. C. Tsai, S. S. Lin, and J. T. Cheng. Effect of premedication on the changes of neuropeptide Y (NPY) in anesthesia. Ma Tsui Hsueh Tsa Chi 30: 147-152, 1992.
7. Chomczynski, P., and N. Sacchi. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
8. Clark, J. T., P. S. Kalra, W. R. Crowley, and S. P. Kalra. Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats. Endocrinology 115: 427-429, 1984.
9. Contreras, R. J., T. Kosten, and E. Bird. Area postrema: part of the autonomic circuitry of caloric homeostasis. Federation Proc. 43: 2966-2968, 1984.
10. Edwards, G. L., and R. C. Ritter. Ablation of the area postrema causes exaggerated consumption of preferred foods in the rat. Brain Res. 216: 265-276, 1981.
11. Giraudo, S. Q., C. J. Billington, and A. S. Levine. Effect of the opioid antagonist naltrexone on feeding induced by DAMGO in the central nucleus of the amygdala and in the paraventricular nucleus in the rat. Brain Res. 782: 18-23, 1998.
12. Giraudo, S. Q., C. M. Kotz, M. K. Grace, C. J. Billington, and A. S. Levine. Differences in rat hypothalamic NPY mRNA and brown fat uncoupling protein mRNA after one week of high-carbohydrate or high-fat diets. Am. J. Physiol. 266 (Regulatory Integrative Comp. Physiol. 35): R1578-R1583, 1994.
13. Gosnell, B. A., and A. S. Levine. Stimulation of Ingestive Behavior by Preferential and Selective Opioid Agonists. New York: Academic, 1996.
14. Kirchgessner, A. L., and A. Sclafani. PVN-hindbrain pathway involved in the hypothalamic hyperphagia-obesity syndrome. Physiol. Behav. 42: 517-528, 1988.
15. Kirchgessner, A. L., A. Sclafani, and G. Nilaver. Histochemical identification of a PVN-hindbrain feeding pathway. Physiol. Behav. 42: 529-543, 1988.
16. Kotz, C. M., C. J. Billington, and A. S. Levine. Opioids in the nucleus of the solitary tract are involved in feeding in the rat. Am. J. Physiol. 272 (Regulatory Integrative Comp. Physiol. 41): R1028-R1032, 1997.