Agouti-related protein containing nerve terminals innervate thyrotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus

Endocrinology

Volumn 140, Issue 8, 1999, Pages 3643-3652

  Légrádi, Gábor ^a   Lechan, Ronald M ^a,b  

^a TUFTS MEDICAL CENTER   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGOUTI RELATED PROTEIN; GLUTAMATE SODIUM; NEUROPEPTIDE Y; PROTEIN DERIVATIVE; PROTIRELIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; HYPOTHALAMUS; HYPOTHALAMUS NUCLEUS; HYPOTHALAMUS PERIVENTRICULAR NUCLEUS; IMMUNOREACTIVITY; INNERVATION; MALE; NERVE ENDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; SYNAPSE;

EID: 0033304761     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.140.8.6935     Document Type: Article

References (46)

1. Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor
2. Mechanisms for the pleiotropic effects of the agouti gene
3. Targeted disruption of the melanocortin4 receptor results in obesity in mice
4. Hypothalamic expression of ART, a novel gene related to agouti, is up- regulated in obese and diabetic mutant mice
5. Barsh G.S. 1997 Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
6. Overexpression of Agrt leads to obesity in transgernic mice
7. Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons
8. The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice
9. Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting and in ob/ob and db/db mice, but is stimulated by leptin
10. Hypothalamic agouti-related protein messenger ribonucleiC acid is inhibited by leptin and stimulated by fasting
11. Neuropeptide-Y-immunoreactive innervation of thyrotropin-releasing hormone-synthesizing neurons in the rat hypothalamic paraventricular nucleus
12. The arcuate nucleus is the major source for neuropeptide Y-innervation of thyrStropin releasing hormone neurons in the hypothalamic paraventricular nucleus
13. Segregation of the intra- and extrahypothalamic neuropeptide Y and catecholaminergic inputs on paraventricular neurons, including those producing thyrotropin-releasing hormone
14. Characterization of the neuroanatomical distribution of agouti-related protein immunoreactivity in the Rhesus monkey and the rat
15. Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate
16. Effects of monosodium L-glutamate administration on neuropeptide Y-containing neurons in the rat hypothalamus
17. Immunohistochemical localization of thyro-tropin-releasing hormone in the rat hypothalamus and pituitary
18. A light and electron microscopic procedure for sequential double antigen localization using diaminobenzidine and benzidine dihydrochloride
19. Ultrastructural characterization of neurons recorded intracellularly in vivo and injected with lucifer yellow: Advantages of immunogold-silver vs. immunoperoxidase labeling
20. Amygdaloid corticotropin releasing factor targets locus coervleus dendrites: Substrate for the co-ordination of emotional and cognitive limbs of the stress response
21. Obesity and the hypothalamus: Novel peptides for new pathways
22. Thermogenesis and thyroid function
23. Neuroendocrine regulation of thyrotropin-releasing hormone (TRH) in the tuberoinfundibular system
24. Inhibition of hypothalamic thyrotropin-releasing hormone messenger ribonuclelc acid during food deprivation
25. Effect of starvation and subsequent refeeding on thyroid function and release of hypothalamic thyrotropin-releasing hormone
26. Leptin prevents fasting-induced suppression of prothyrotropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus
27. Identification of targets of leptin action in rat hypothalamus
28. Arcuate nucleus ablation prevents fasting-induced suppression of ProTRH mRNA in the hypothalamic paraventricular nucleus
29. Neuropeptide Y: Anatomical distribution and possible function in mammalian nervous system
30. Rapid and localized alterations of neuropeptide Y in discrete hypothalamic nuclei with feeding status
31. Interactions between leptin and hypothalamic neuropeptide Y neurons in the control of food intake and energy homeostasis in the rat
32. Further studies on the effects of central administration of neuropeptide Y on neuroendocrine function in the male rat: Relationship to hypothalamic cateholamines
33. Endocrine function of neuropeptide Y knockout mice
34. Differential organization of Synapses immunoreactive to phenylethanolamine-N-methyltransferase or neuropeptide Y in the parvicellular compartments of the hypothalamic paraventricular nucleus of the rat
35. Immunocytochemical delineation of thyrotrophic area: Origin of thyrotropin-releasing hormone in the median eminence
36. Immunohistochemical identification of neurons in the paraventricular nucleus of the hypothalamus that project to the medulla or to the spinal cord in the rat
37. A C-terminal fragment of Agouti-related protein increases feeding and antagonizes the effect of alpha-melanocyte stimulating hormone in vivo
38. Anatomical interactions of proopiomelanocortin (POMC)-related peptides, neuropeptide Y (NPY) and dopamine beta-hydroxylase (DβH) fibers and thyrotropin-releas-ing hormone (TRH) neurons in the paraventricular nucleus of rat hypothalamus
39. Effects of α- and β-melanocyte stimulating hormones and other peptides on the thyroid in mice
40. Neurotransmitters, neuropeptides and binding sites in the rat mediobasal hypothalamus: Effects of monosodium glutamate (MSG) lesions
41. Identifcation, characterization and stereotaxic mapping of intraneuronal alpha-melanocyte stimulating hormone-like immunoreactive peptides in discrete regions of the rat brain
42. MSG effects on beta-endorphin and alpha-MSH in the hypothalamus and caudal medulla
43. Determination of disulfide structure in agoutirelated protein (AGRP) by stepwise reduction and alkylation
44. Inhibition of N- and P/Q-type calcium channels by postsynaptic GABAB receptor activation in rat supraoptic neurones
45. Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain
46. Effects of preoptic microinjections of α- MSH on fever and normal temperature control in rabbits