Histamine H3-receptor isoforms

Inflammation Research

Volumn 53, Issue 10, 2004, Pages 509-516

  Bakker, R A ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Brain expression of H3 R; CNS functions; Histamine H3 receptors; Neurotransmitter

Indexed keywords

HISTAMINE H3 RECEPTOR; HISTAMINE H4 RECEPTOR; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; ANTIHISTAMINIC AGENT; ISOPROTEIN; LIGAND;

BRAIN FUNCTION; COGNITION; DRUG TARGETING; EMOTION; FEEDING; GENE EXPRESSION; HUMAN; MOLECULAR CLONING; NEUROTRANSMISSION; NONHUMAN; NUCLEOTIDE SEQUENCE; REVIEW; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; BRAIN; CENTRAL NERVOUS SYSTEM; CHEMICAL MODEL; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; RAT; SEQUENCE HOMOLOGY; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; ANIMALS; BRAIN; CENTRAL NERVOUS SYSTEM; HISTAMINE ANTAGONISTS; HUMANS; LIGANDS; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; NEUROTRANSMITTER AGENTS; PROTEIN ISOFORMS; RATS; RECEPTORS, HISTAMINE H3; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION;

EID: 12144282438     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00011-004-1286-9     Document Type: Review

References (90)

1. 2-receptors. Nature 1972; 236: 385-90.
2. 1 receptor. Biochem Biophys Res Commun 1993; 197: 1601-8.
3. 1 receptor gene. Biochem J 1998; 335: 663-70.
4. 1 receptor. Biochem Biophys Res Commun 1993; 190: 294-301.
5. 1 receptor gene. Biochem Biophys Res Commun 1994; 201: 894-901.
6. 2 receptor. Proc Natl Acad Sci USA 1991; 88: 429-33.
7. 2 receptor. Biochem Biophys Res Commun 1991; 178: 1386-92.
8. 1 receptor gene. J Biochem (Tokyo) 1993; 114: 408-14.
9. 1 receptor gene. Genomics 1996; 36: 178-81.
10. 2receptor gene. Genomics 1996; 37: 390-4.
11. 1-histamine-receptor cDNA in Chinese hamster ovary cells. Pharmacological characterisation of the protein, tissue distribution of messenger RNA and chromosomal localisation of the gene. Eur J Biochem 1994; 224: 489-95.
12. 2-receptor gene. Biochem Biophys Res Commun 1991; 179: 1470-8.
13. 2 receptor mediating inhibition of arachidonate release and activation of cAMP accumulation. Proc Natl Acad Sci USA 1992; 89: 2649-53.
14. 1 receptor. I. Gene cloning, characterization, and tissue expression revealed by in situ hybridization. J Neurochem 1994; 62: 507-18.
15. 2 receptor: gene cloning, tissue expression and chromosomal localization of its human counterpart. Biochem Biophys Res Commun 1995; 211: 570-7.
16. 1 receptor. Proc Natl Acad Sci USA 1991; 88: 11515-9.
17. 3) of histamine receptor. Nature 1983; 302: 832-7.
18. 3 receptor agonists and antagonists. Trends Pharmacol Sci 1998; 19: 177-83.
19. 3 receptor. Mol Pharmacol 1999; 55: 1101-7.
20. 3 receptor reveals distinct species pharmacological profiles. J. Pharmacol Exp Ther 2000; 293: in press.
21. 3 receptor: evidence for two isoforms. Neuroreport 2000; 11: 755-9.
22. 3 receptor. European Journal of Pharmacology 2003; 467: 57-65.
23. Nakamura T, Itadani H, Hidaka Y, Ohta M, Tanaka K. Molecular cloning and characterization of a new human histamine receptor, HH4R. Biochem Biophys Res Commun 2000; 279: 615-20.
24. Zhu Y, Michalovich D, Wu HL, Tan KB, Dytko GM, Mannan IJ et al. Cloning, Expression, and Pharmacological Characterization of a Novel Human Histamine Receptor. Mol Pharmacol 2001; 59: 434-41.
25. 4) Expressed in Bone Marrow. Mol Pharmacol 2001; 59: 420-6.
26. Morse KL, Behan J, Laz TM, West RE, Greenfeder SA, Anthes JC et al. Cloning and Characterization of a Novel Human Histamine Receptor. J Pharmacol Exp Ther 2001; 296: 1058-66.
27. Oda T, Morikawa N, Saito Y, Masuho Y, Matsumoto S. Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes. J Biol Chem 2000; 275: 36781-6.
28. 4 receptor. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 2002; 1575: 135-8.
29. 3 receptors results in changes in brain histamine tone leading to an obese phenotype. J Clin Invest 2002; 110: 1791-9.
30. 3 Receptors. Mol Pharmacol 2002; 62: 389-97.
31. 3 receptors. Mol Pharmacol 2003; 63: 378-82.
32. 3 receptor binding sites in rat brain membranes: modulations by guanine nucleotides and divalent cations. Eur J Pharmacol 1990; 188: 219-27.
33. 3 histamine receptor. J Neurochem 1990; 55: 1612-6.
34. 3 histamine receptor subtypes. Mol. Pharmacol. 1990; 38: 610-3.
35. 125I]-iodophen-propit, to rat brain. Br J Pharmacol 1994; 113: 355-62.
36. 3-receptors. Br J Pharmacol 1992; 107: 347-51.
37. 3A receptor-mediated inhibition of noradrenaline release in the mouse brain cortex. Naunyn Schmiedebergs Arch Pharmacol 1992; 345: 489-93.
38. 3 receptor subtypes. Br J Pharmacol 1992; 107: 919-23.
39. 3 receptor heterogeneity? J Pharmacol Exp Ther 1996; 276: 1009-15.
40. 3 receptor. Neuropharmacology 2002; 42: 929-40.
41. 3 receptor. Biochem J 2001; 355: 279-88.
42. 3 receptor isoforms with different brain expression and signaling properties. Mol Pharmacol 2001; 59: 1-8.
43. 3 receptor: gene organization and multiple isoforms. Biochem Biophys Res Commun 2001; 280: 75-80.
44. 4 histamine receptor. Soc Neurosci Abstr 2001; 27.
45. 3 receptor gene. Neuroreport 2001; 12: 321-4.
46. 3) and identification of naturally occurring variations. J Neural Transm 2002; 109: 443-53.
47. 3 receptor mRNA at the third cytoplasmic loop is not detectable in humans. Brain Res Mol Brain Res 2000; 83: 145-50.
48. 2 short isoform in dopaminergic pathways. Proc Natl Acad Sci USA 1998; 95: 7731-6.
49. 3 receptors regulates histamine neurons in brain. Nature 2000; 408: 860-4.
50. 3 receptors in the brain of 6-hydroxydopamine- lesioned rats. Eur J Neurosci 2000; 12: 3823-32.
51. 3 receptor isoforms in the thalamus of kainic acid-treated rats, FENS Forum 2002, Bordeaux, 14/7/2002, 2002.
52. 2 dopamine receptors produced by alternative RNA splicing. Nature 1989; 342: 926-9.
53. 2 dopamine receptor isoforms. Nature 1989; 342: 923-6.
54. English JD, Sweatt JD. Activation of p42 mitogen-activated protein kinase in hippocampal long term potentiation. J Biol Chem 1996; 271: 24329-32.
55. Bhalla US, Iyengar R. Emergent properties of networks of biological signaling pathways. Science 1999; 283: 381-7.
56. 2S receptor isoforms in the regulation of protein phosphorylation at presynaptic and post-synaptic sites. PNAS 2003; 100: 4305-9.
57. 2L receptors. Neuropsychopharmacology 2002; 27: 723-6.
58. 2 dopamine receptor messenger ribonucleic acid is modulated by activated sex steroid receptors in the MMQ prolactin cell line. Endocrinology 1998; 139: 4213-21.
59. 2 long receptor-deficient mice display alterations in striatum-dependent functions. J Neurosci 2000; 20: 8305-14.
60. Klemm JD, Schreiber SL, Crabtree GR. Dimerization as a regulatory mechanism in signal transduction. Annu Rev Immunol 1998; 16: 569-92.
61. Angers S, Salahpour A, Joly E, Hilairet S, Chelsky D, Dennis M et al. Detection of β2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET). Proc Natl Acad Sci USA 2000; 97: 3684-9.
62. Jordan BA, Devi LA. G-protein-coupled receptor heterodimerization modulates receptor function. Nature 1999; 399: 697-700.
63. 5 and γ-aminobutyric acid A receptors. Nature 2000; 403: 274-80.
64. Pfeiffer M, Koch T, Schröder H, Laugsch M, Höllt V, Schulz S. Heterodimerization of Somatostatin and Opioid Receptors Cross-modulates Phosphorylation, Internalization, and Desensitization. J Biol Chem 2002; 277: 19762-72.
65. 2A. J Biol Chem 2000; 27: 27.
66. 1 receptors form functionally interacting heteromeric complexes. Proc Natl Acad Sci USA 2000; 97: 8606-11.
67. Rocheville M, Lange DC, Kumar U, Patel SC, Patel RC, Patel YC. Receptors for dopamine and somatostatin: formation of heterooligomers with enhanced functional activity. Science 2000; 288: 154-7.
68. Kenakin T. The classification of seven transmembrane receptors in recombinant expression systems. Pharmacol Rev 1996; 48: 413-63.
69. De Lean A, Stadel JM, Lefkowitz RJ. A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled β-adrenergic receptor. J Biol Chem 1980; 255: 71108-17.
70. Leurs R, Smit MJ, Alewijnse AE, Timmerman H. Agonist-independent regulation of constitutively active G-protein-coupled receptors. Trends Biochem Sci 1998; 23: 418-22.
71. Milligan G, Bond RA. Inverse agonism and the regulation of receptor number. Trends Pharmacol Sci 1997; 18: 468-74.
72. Milligan G, Bond RA, Lee M. Inverse agonism: pharmacological curiosity or potential therapeutic strategy? Trends Pharmacol Sci 1995; 16: 10-3.
73. Lefkowitz RJ, Cotecchia S, Samama P, Costa T. Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins. Trends Pharmacol Sci 1993; 14: 303-7.
74. 2-adrenergic receptor. Extending the ternary complex model. J Biol Chem 1993; 268: 4625-36.
75. Leff P. The two-state model of receptor activation. Trends Pharmacol Sci 1995; 16: 89-97.
76. Weiss JM, Morgan PH, Lutz MW, Kenakin TP. The cubic ternary complex receptor-occupancy model. III. resurrecting efficacy. J Theor Biol 1996; 181: 381-97.
77. Schutz W, Freissmuth M. Reverse intrinsic activity of antagonists on G protein-coupled receptors. Trends Pharmacol Sci 1992; 13: 376-80.
78. Costa T, Herz A. Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins. Proc Natl Acad Sci USA 1989; 86: 7321-5.
79. 2 dopamine receptor in a reconstituted system. J Biol Chem 1990; 265: 4507-14.
80. Munshi R, Pang IH, Sternweis PC, Linden J. A1 adenosine receptors of bovine brain couple to guanine nucleotide- binding proteins Gi1, Gi2, and Go. J Biol Chem 1991; 266: 22285-9.
81. Burstein ES, Spalding TA, Brann MR. Pharmacology of muscarinic receptor subtypes constitutively activated by G proteins. Mol. Pharmacol. 1997; 51: 312-9.
82. Burstein ES, Spalding TA, Bräuner-Osborne H, Brann MR. Constitutive activation of muscarinic receptors by the G-protein Gq. FEBS Lett 1995; 363: 261-3.
83. 1B-adrenergic receptor enhances mitogenesis and tumorigenicity. Proc Natl Acad Sci USA 1991; 88: 11354-8.
84. Dosil M, Giot L, Davis C, Konopka JB. Dominant-negative mutations in the G-protein-coupled alpha-factor receptor map to the extracellular ends of the transmembrane segments. Mol Cell Biol 1998; 18: 5981-91.
85. 1B-adrenergic receptor signal-inactivating point mutation. Embo J 2000; 19: 4265-71.
86. 1 receptor antagonists. Eur J Pharmacol 2000; 387: R5-7.
87. 2 receptors. Proc Natl Acad Sci USA 1996; 93: 6802-7.
88. 3 antagonists. J Pharmacol Exp Ther 2001; 299: 908-14.
89. 3 receptors. Br J Pharmacol 2002; 135: 383-92.
90. 3 receptor heterogeneity. Neuropharmacology 2003; 44: 773-86.