-
1
-
-
0028588064
-
Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma
-
Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, Knowles DM et al. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 1994; 266: 1865-1869.
-
(1994)
Science
, vol.266
, pp. 1865-1869
-
-
Chang, Y.1
Cesarman, E.2
Pessin, M.S.3
Lee, F.4
Culpepper, J.5
Knowles, D.M.6
-
2
-
-
0032009981
-
HIV-1, HHV-8, and Kaposi's sarcoma
-
Gallo RC. HIV-1, HHV-8, and Kaposi's sarcoma.J Hum Virol 1998; 1: 185-186.
-
(1998)
J. Hum. Virol.
, vol.1
, pp. 185-186
-
-
Gallo, R.C.1
-
3
-
-
0037721575
-
Molecular biology and pathogenesis of Kaposi sarcoma-associated herpesvirus
-
Verma SC, Roberson ES. Molecular biology and pathogenesis of Kaposi sarcoma-associated herpesvirus. FEMS Microbiol Lett 2003; 222: 155-163.
-
(2003)
FEMS Microbiol. Lett.
, vol.222
, pp. 155-163
-
-
Verma, S.C.1
Roberson, E.S.2
-
4
-
-
0036727618
-
Virology, pathogenetic mechanisms, and associated diseases of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8)
-
Sarid R, Klepfish A, Schattner A. Virology, pathogenetic mechanisms, and associated diseases of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8). Mayo Clin Proc 2002; 77: 941-949.
-
(2002)
Mayo Clin. Proc.
, vol.77
, pp. 941-949
-
-
Sarid, R.1
Klepfish, A.2
Schattner, A.3
-
5
-
-
0036310661
-
Spectrum of Kaposi's sarcoma-associated herpesvirus, or human herpesvirus 8, diseases
-
Ablashi DV, Chatlynne LG, Whitman Jr JE, Cesarman E. Spectrum of Kaposi's sarcoma-associated herpesvirus, or human herpesvirus 8, diseases. Clin Microbiol Rev 2002; 15: 439-464.
-
(2002)
Clin. Microbiol. Rev.
, vol.15
, pp. 439-464
-
-
Ablashi, D.V.1
Chatlynne, L.G.2
Whitman Jr., J.E.3
Cesarman, E.4
-
6
-
-
0034969034
-
Biology of Kaposi's sarcoma
-
Ensoli B, Sgadari C, Barillari G, Sirianni MC, Sturzl M, Monini P. Biology of Kaposi's sarcoma. Eur J Cancer 2001; 37: 1251-1269.
-
(2001)
Eur. J. Cancer
, vol.37
, pp. 1251-1269
-
-
Ensoli, B.1
Sgadari, C.2
Barillari, G.3
Sirianni, M.C.4
Sturzl, M.5
Monini, P.6
-
7
-
-
2342452425
-
Micronodular Kaposi's sarcoma - A new variant of classic-sporadic Kaposi's sarcoma
-
Kempf W, Cathomas G, Burg G, Trueb RM. Micronodular Kaposi's sarcoma - a new variant of classic-sporadic Kaposi's sarcoma. Dermatology 2004; 208: 255-258.
-
(2004)
Dermatology
, vol.208
, pp. 255-258
-
-
Kempf, W.1
Cathomas, G.2
Burg, G.3
Trueb, R.M.4
-
8
-
-
0034971887
-
KSHV/HHV8-associated lymphoproliferations in the AIDS setting
-
Schulz TF. KSHV/HHV8-associated lymphoproliferations in the AIDS setting. Eur J Cancer 2001; 37: 1217-1226.
-
(2001)
Eur. J. Cancer
, vol.37
, pp. 1217-1226
-
-
Schulz, T.F.1
-
9
-
-
0033762395
-
Cytokine-mediated growth promotion of Kaposi's sarcoma and primary effusion lymphoma
-
Ensoli B, Sturzl M, Monini P. Cytokine-mediated growth promotion of Kaposi's sarcoma and primary effusion lymphoma. Cancer Biol 2000; 10: 367-381.
-
(2000)
Cancer Biol.
, vol.10
, pp. 367-381
-
-
Ensoli, B.1
Sturzl, M.2
Monini, P.3
-
10
-
-
0036827540
-
Kaposi's sarcoma and other manifestations of human herpesvirus 8
-
Geraminejad P, Memar O, Aronson I, Rady PL, Hengge U, Tyring SK. Kaposi's sarcoma and other manifestations of human herpesvirus 8. J Am Acad Dermatol 2002; 47: 641-655.
-
(2002)
J. Am. Acad. Dermatol.
, vol.47
, pp. 641-655
-
-
Geraminejad, P.1
Memar, O.2
Aronson, I.3
Rady, P.L.4
Hengge, U.5
Tyring, S.K.6
-
11
-
-
0036275066
-
Update on Kaposi's sarcoma and other HHV8 associated diseases. Part 2: Pathogenesis, Castleman's disease, and pleural effusion lymphoma
-
Hengge UR, Ruzicka T, Tyring SK, Stuschke M, Roggendorf M, Schwartz RA et al. Update on Kaposi's sarcoma and other HHV8 associated diseases. Part 2: pathogenesis, Castleman's disease, and pleural effusion lymphoma. Lancet 2002; 2: 344-352.
-
(2002)
Lancet
, vol.2
, pp. 344-352
-
-
Hengge, U.R.1
Ruzicka, T.2
Tyring, S.K.3
Stuschke, M.4
Roggendorf, M.5
Schwartz, R.A.6
-
12
-
-
0034614893
-
Viral G protein-coupled receptor and Kaposi's sarcoma: A model of paracrine neoplasia
-
Cesarman E, Mesri EA, Gershengorn MC. Viral G protein-coupled receptor and Kaposi's sarcoma: a model of paracrine neoplasia. J Exp Med 2000; 191: 417-421.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 417-421
-
-
Cesarman, E.1
Mesri, E.A.2
Gershengorn, M.C.3
-
13
-
-
0001640974
-
Human herpes virus 8 interleukin-6 homologue triggers gp130 on neuronal and hematopoietic cells
-
Hoischen SH, Vollmer P, Marz P, Ozbek S, Gotze KS, Peschel C et al. Human herpes virus 8 interleukin-6 homologue triggers gp130 on neuronal and hematopoietic cells. Eur J Biochem 2000; 267: 3604-3612.
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 3604-3612
-
-
Hoischen, S.H.1
Vollmer, P.2
Marz, P.3
Ozbek, S.4
Gotze, K.S.5
Peschel, C.6
-
14
-
-
10744230540
-
Selective expression of stromal-derived factor-1 in the capillary vascular endothelium plays a role in Kaposi sarcoma pathogenesis
-
Yao L, Salvucci O, Cardones AR, Hwang ST, Aoki Y, De La Luz Sierra M et al. Selective expression of stromal-derived factor-1 in the capillary vascular endothelium plays a role in Kaposi sarcoma pathogenesis. Blood 2003; 102: 3900-3905.
-
(2003)
Blood
, vol.102
, pp. 3900-3905
-
-
Yao, L.1
Salvucci, O.2
Cardones, A.R.3
Hwang, S.T.4
Aoki, Y.5
De La Luz Sierra, M.6
-
15
-
-
0037089405
-
Regulation of endothelial cell branching morphogenesis by endogenous chemokine stromal-derived factor-1
-
Salvucci O, Yao L, Villalba S, Sajewicz A, Pittaluga S, Tosato G. Regulation of endothelial cell branching morphogenesis by endogenous chemokine stromal-derived factor-1. Blood 2002; 99 2703-2711.
-
(2002)
Blood
, vol.99
, pp. 2703-2711
-
-
Salvucci, O.1
Yao, L.2
Villalba, S.3
Sajewicz, A.4
Pittaluga, S.5
Tosato, G.6
-
17
-
-
0028675659
-
The interleukin-1 family: 10 years of discovery
-
Dinarello CA. The interleukin-1 family: 10 years of discovery. FASEB J 1994; 8: 1314-1325.
-
(1994)
FASEB J.
, vol.8
, pp. 1314-1325
-
-
Dinarello, C.A.1
-
18
-
-
0036435625
-
Interleukin-1 beta increases the BCL-2/BAX ratio in Kaposi's sarcoma cells
-
Simonart T, Van Vooren JP. Interleukin-1 beta increases the BCL-2/BAX ratio in Kaposi's sarcoma cells. Cytokine 2002; 19: 259-266.
-
(2002)
Cytokine
, vol.19
, pp. 259-266
-
-
Simonart, T.1
Van Vooren, J.P.2
-
19
-
-
0030942815
-
Role of interleukin-1 beta converting enzyme (ICE) in acute myelogenous leukemia cell proliferation and programmed cell death
-
Estrov Z, Talpaz M. Role of interleukin-1 beta converting enzyme (ICE) in acute myelogenous leukemia cell proliferation and programmed cell death. Leukemia Lymphoma 1997; 24: 379-391.
-
(1997)
Leukemia Lymphoma
, vol.24
, pp. 379-391
-
-
Estrov, Z.1
Talpaz, M.2
-
20
-
-
84925549112
-
The paradigm of IL-6: From basic science to medicine
-
Naka T, Nishimoto N, Kishimoto T. The paradigm of IL-6: from basic science to medicine. Arthritis Res 2002; 4: S233-S242.
-
(2002)
Arthritis Res.
, vol.4
-
-
Naka, T.1
Nishimoto, N.2
Kishimoto, T.3
-
21
-
-
0032030338
-
Interleukin-8 (IL-8) and monocyte chemotactic and activating factor (MCAF/MCP-1), chemokines essentially involved in inflammatory and immune reactions
-
Mukaida N, Harada A, Matsushima K. Interleukin-8 (IL-8) and monocyte chemotactic and activating factor (MCAF/MCP-1), chemokines essentially involved in inflammatory and immune reactions. Cytokine Growth Factor Rev 1998; 9: 9-23.
-
(1998)
Cytokine Growth Factor Rev.
, vol.9
, pp. 9-23
-
-
Mukaida, N.1
Harada, A.2
Matsushima, K.3
-
22
-
-
0034024955
-
Interleukin 8 (IL-8) and the release of leukocytes from the bone marrow
-
van Eeden SF, Terashima T. Interleukin 8 (IL-8) and the release of leukocytes from the bone marrow. Leukemia Lymphoma 2000; 37: 259-271.
-
(2000)
Leukemia Lymphoma
, vol.37
, pp. 259-271
-
-
van Eeden, S.F.1
Terashima, T.2
-
23
-
-
0033913570
-
IL-8 expression in malignant melanoma: Implications in growth and metastasis
-
Singh RK, Varney ML. IL-8 expression in malignant melanoma: implications in growth and metastasis. Histol Histopathol 2000; 15: 843-849.
-
(2000)
Histol. Histopathol.
, vol.15
, pp. 843-849
-
-
Singh, R.K.1
Varney, M.L.2
-
24
-
-
1842843584
-
Expression of angiogenic factors and cell cycle regulation factors in human glioblastoma cell line SHG-44
-
Bian X, Chen Z, Guo D, Du L, Xin R, Shi J. Expression of angiogenic factors and cell cycle regulation factors in human glioblastoma cell line SHG-44. Zhonghua Bing Li Xue Za Zhi 1999; 28: 178-181.
-
(1999)
Zhonghua Bing Li Xue Za Zhi
, vol.28
, pp. 178-181
-
-
Bian, X.1
Chen, Z.2
Guo, D.3
Du, L.4
Xin, R.5
Shi, J.6
-
25
-
-
2642586618
-
MCP-1-dependent signaling in CCR2-/- aortic smooth muscle cells
-
Schecter AD, Berman AB, Yi L, Ma H, Daly CM, Soejima K et al. MCP-1-dependent signaling in CCR2-/- aortic smooth muscle cells. J Leukocyte Biol 2004; 75: 1079-1085.
-
(2004)
J. Leukocyte Biol.
, vol.75
, pp. 1079-1085
-
-
Schecter, A.D.1
Berman, A.B.2
Yi, L.3
Ma, H.4
Daly, C.M.5
Soejima, K.6
-
26
-
-
0036232326
-
Signaling via the interferon-α receptor in chronic myelogenous leukemia cells
-
Verma A, Platanias LC. Signaling via the interferon-α receptor in chronic myelogenous leukemia cells. Leukemia Lymphoma 2002; 43: 703-709.
-
(2002)
Leukemia Lymphoma
, vol.43
, pp. 703-709
-
-
Verma, A.1
Platanias, L.C.2
-
27
-
-
0034606671
-
Inflammatory cytokines and the reactivation of Kaposi's sarcoma associated herpesvirus lytic replication
-
Chang J, Renne R, Dittmer D, Ganem D. Inflammatory cytokines and the reactivation of Kaposi's sarcoma associated herpesvirus lytic replication. Virology 2000; 266: 17-25.
-
(2000)
Virology
, vol.266
, pp. 17-25
-
-
Chang, J.1
Renne, R.2
Dittmer, D.3
Ganem, D.4
-
28
-
-
0348223726
-
Lessons from 10 years of interferon beta-1b (Betaferon/Betaseron) treatment
-
Bayas A, Gold R. Lessons from 10 years of interferon beta-1b (Betaferon/Betaseron) treatment. J Neurol 2003; 250: IV3-IV8.
-
(2003)
J. Neurol.
, vol.250
-
-
Bayas, A.1
Gold, R.2
-
29
-
-
0031463988
-
Interferon-beta not only inhibits interleukin-1beta and tumor necrosis factor-alpha but stimulates interleukin-1 receptor antagonist production in human peripheral blood mononuclear cells
-
Coclet-Ninin J, Dayer JM, Burger D. Interferon-beta not only inhibits interleukin-1beta and tumor necrosis factor-alpha but stimulates interleukin-1 receptor antagonist production in human peripheral blood mononuclear cells. Eur Cytokine Networks 1997; 8: 345-349.
-
(1997)
Eur. Cytokine Networks
, vol.8
, pp. 345-349
-
-
Coclet-Ninin, J.1
Dayer, J.M.2
Burger, D.3
-
30
-
-
0029819030
-
Regulation of interferon-gamma gene expression
-
Young HA. Regulation of interferon-gamma gene expression. J Interferon Cytokine Res 1996; 16: 563-568.
-
(1996)
J. Interferon Cytokine Res.
, vol.16
, pp. 563-568
-
-
Young, H.A.1
-
31
-
-
0842266786
-
Interferon-gamma: An overview of signals, mechanisms and functions
-
Schroder K, Hertzog PJ, Ravasi T, Hume DA. Interferon-gamma: an overview of signals, mechanisms and functions. J Leukocyte Biol 2004; 75: 163-189.
-
(2004)
J. Leukocyte Biol.
, vol.75
, pp. 163-189
-
-
Schroder, K.1
Hertzog, P.J.2
Ravasi, T.3
Hume, D.A.4
-
32
-
-
0028535921
-
Lipopolysaccharide signals activation of tumor necrosis factor biosynthesis through the ras/raf-1/MEK/MAPK pathway
-
Geppert TD, Whitehurst CE, Thompson P, Beutler B. Lipopolysaccharide signals activation of tumor necrosis factor biosynthesis through the ras/raf-1/MEK/MAPK pathway. Mol Med 1994; 1: 93-103.
-
(1994)
Mol. Med.
, vol.1
, pp. 93-103
-
-
Geppert, T.D.1
Whitehurst, C.E.2
Thompson, P.3
Beutler, B.4
-
33
-
-
0038445485
-
Multiple roles for tumor necrosis factor-alpha and lymphotoxin alpha/beta in immunity and autoimmunity
-
McDevitt H, Munson S, Ettinger R, Wu A. Multiple roles for tumor necrosis factor-alpha and lymphotoxin alpha/beta in immunity and autoimmunity. Arthritis Res 2002; 4: S141-S152.
-
(2002)
Arthritis Res.
, vol.4
-
-
McDevitt, H.1
Munson, S.2
Ettinger, R.3
Wu, A.4
-
34
-
-
0242643609
-
Autocrine lymphotoxin production in Epstein-Barr virus-immortalized B cells: Induction via NF-kappaB activation mediated by EBV-derived latent membrane protein 1
-
Thompson MP, Aggarwal BB, Shishodia S, Estrov Z, Kurzrock R. Autocrine lymphotoxin production in Epstein-Barr virus-immortalized B cells: induction via NF-kappaB activation mediated by EBV-derived latent membrane protein 1. Leukemia 2003; 17: 2196-2201.
-
(2003)
Leukemia
, vol.17
, pp. 2196-2201
-
-
Thompson, M.P.1
Aggarwal, B.B.2
Shishodia, S.3
Estrov, Z.4
Kurzrock, R.5
-
36
-
-
0141613833
-
Transforming growth factor-beta signaling in normal and malignant hematopoiesis
-
Kim SJ, Letterio J. Transforming growth factor-beta signaling in normal and malignant hematopoiesis. Leukemia 2003; 17: 1731-1737.
-
(2003)
Leukemia
, vol.17
, pp. 1731-1737
-
-
Kim, S.J.1
Letterio, J.2
-
37
-
-
0034988689
-
Vascular endothelial growth factor/vascular permeability factor in the pathogenesis of primary effusion lymphomas
-
Aoki Y, Tosato G. Vascular endothelial growth factor/vascular permeability factor in the pathogenesis of primary effusion lymphomas. Leukemia Lymphoma 2001; 41: 229-237.
-
(2001)
Leukemia Lymphoma
, vol.41
, pp. 229-237
-
-
Aoki, Y.1
Tosato, G.2
-
38
-
-
1942541107
-
Granulocyte colony stimulating factor (G-CSF) as an adjunct to antibiotics in the treatment of pneumonia in adults
-
Cheng AC, Stephens DP, Currie BJ. Granulocyte colony stimulating factor (G-CSF) as an adjunct to antibiotics in the treatment of pneumonia in adults. Cochrane Database Syst Rev 2003; 4: CD004400.
-
(2003)
Cochrane Database Syst. Rev.
, vol.4
-
-
Cheng, A.C.1
Stephens, D.P.2
Currie, B.J.3
-
39
-
-
0036142704
-
Human herpesvirus-8-transformed endothelial cells have functionally activated vascular endothelial growth factor/vascular endothelial growth factor receptor
-
Masood R, Cesarman E, Smith DL, Gill PS, Flore O. Human herpesvirus-8-transformed endothelial cells have functionally activated vascular endothelial growth factor/vascular endothelial growth factor receptor. Am J Pathol 2002; 160: 23-29.
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 23-29
-
-
Masood, R.1
Cesarman, E.2
Smith, D.L.3
Gill, P.S.4
Flore, O.5
-
40
-
-
0028028035
-
Biosynthesis and processing by phorbo ester of the cells surface associated precursor form of heparin-binding EGF-like growth factor
-
Raab G, Higashiyama S, Hetelekidis S, Abraham JA, Damm D, Ono M et al. Biosynthesis and processing by phorbo ester of the cells surface associated precursor form of heparin-binding EGF-like growth factor. Biochem Biophys Res Commun 1994; 204: 592-597.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.204
, pp. 592-597
-
-
Raab, G.1
Higashiyama, S.2
Hetelekidis, S.3
Abraham, J.A.4
Damm, D.5
Ono, M.6
-
41
-
-
0028963636
-
The membrane protein CD9/DRAP27 potentiates the justacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor
-
Higashiyama S, Iwamoto R, Goishi K, Raab G, Taniguchi N, Klagsbrun M et al. The membrane protein CD9/DRAP27 potentiates the justacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor. J Cell Biol 1995; 128 929-938.
-
(1995)
J. Cell Biol.
, vol.128
, pp. 929-938
-
-
Higashiyama, S.1
Iwamoto, R.2
Goishi, K.3
Raab, G.4
Taniguchi, N.5
Klagsbrun, M.6
-
43
-
-
0034600849
-
The ErbB signaling network: Receptor heterodimerization in development and cancer
-
Olayioye MA, Neve RM, Lane HA, Hynes NE. The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J 2000; 19: 3159-3167.
-
(2000)
EMBO J.
, vol.19
, pp. 3159-3167
-
-
Olayioye, M.A.1
Neve, R.M.2
Lane, H.A.3
Hynes, N.E.4
-
44
-
-
0028074527
-
Characterization of sequences within heparin-binding EGF-like growth factor that mediate interaction with heparin
-
Thompson SA, Higashiyamanll S, Wood K, Pollitt NS, Damm D, McEnroe G et al. Characterization of sequences within heparin-binding EGF-like growth factor that mediate interaction with heparin. J Biol Chem 1994; 269: 2541-2549.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 2541-2549
-
-
Thompson, S.A.1
Higashiyamanll, S.2
Wood, K.3
Pollitt, N.S.4
Damm, D.5
McEnroe, G.6
-
45
-
-
0036679853
-
GM-CSF in inflammation and autoimmunity
-
Hamilton JA. GM-CSF in inflammation and autoimmunity. Trends Immunol 2002; 23: 403-408.
-
(2002)
Trends Immunol.
, vol.23
, pp. 403-408
-
-
Hamilton, J.A.1
-
48
-
-
0032844762
-
Scatter factor/hepatocyte growth factor (SF/HGF) content and function in human gliomas
-
Lamszus K, Laterra J, Westphal M, Rosen EM. Scatter factor/hepatocyte growth factor (SF/HGF) content and function in human gliomas. Int J Dev Neurosci 1999; 17: 517-530.
-
(1999)
Int. J. Dev. Neurosci.
, vol.17
, pp. 517-530
-
-
Lamszus, K.1
Laterra, J.2
Westphal, M.3
Rosen, E.M.4
-
49
-
-
0028307849
-
Role of scatter factor in the pathogenesis of AIDS-related Kaposi sarcoma
-
Naidu YM, Rosen EM, Zitnick R, Goldberg I, Park M, Naujokas M et al. Role of scatter factor in the pathogenesis of AIDS-related Kaposi sarcoma. Proc Natl Acad Sci USA 1994; 91: 5281-5285.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 5281-5285
-
-
Naidu, Y.M.1
Rosen, E.M.2
Zitnick, R.3
Goldberg, I.4
Park, M.5
Naujokas, M.6
-
50
-
-
0035207172
-
Platelet-derived growth factor receptors: A therapeutic target in solid tumors
-
George D. Platelet-derived growth factor receptors: a therapeutic target in solid tumors. Semin Oncol 2001; 28: 27-33.
-
(2001)
Semin. Oncol.
, vol.28
, pp. 27-33
-
-
George, D.1
-
53
-
-
0033902645
-
Induction of HHV-8 lytic cycle replication by inflammatory cytokines produced by HIV-1-infected T cells
-
Mercader M, Taddeo B, Panella JR, Chandran B, Nickoloff BJ, Foreman KE. Induction of HHV-8 lytic cycle replication by inflammatory cytokines produced by HIV-1-infected T cells. Am J Pathol 2000; 156: 1961-1971.
-
(2000)
Am. J. Pathol.
, vol.156
, pp. 1961-1971
-
-
Mercader, M.1
Taddeo, B.2
Panella, J.R.3
Chandran, B.4
Nickoloff, B.J.5
Foreman, K.E.6
-
54
-
-
1942541169
-
The role of epidermal growth factor and its receptors in mammalian CNS
-
Wong RW, Guillaud L. The role of epidermal growth factor and its receptors in mammalian CNS. Cytokine Growth Factor Rev 2004; 15: 147-156.
-
(2004)
Cytokine Growth Factor Rev.
, vol.15
, pp. 147-156
-
-
Wong, R.W.1
Guillaud, L.2
-
55
-
-
0142040832
-
EGF receptor signaling: Putting a new spin on eye development
-
Wolff T. EGF receptor signaling: putting a new spin on eye development. Curr Biol 2003; 13: R813-R814.
-
(2003)
Curr. Biol.
, vol.13
-
-
Wolff, T.1
-
56
-
-
10744227000
-
Overexpression of basic fibroblast growth factor and autocrine stimulation in acute myeloid leukemia
-
Bieker R, Padro T, Kramer J, Steins M, Kessler T, Retzlaff S et al. Overexpression of basic fibroblast growth factor and autocrine stimulation in acute myeloid leukemia. Cancer Res 2003; 63: 7241-7246.
-
(2003)
Cancer Res.
, vol.63
, pp. 7241-7246
-
-
Bieker, R.1
Padro, T.2
Kramer, J.3
Steins, M.4
Kessler, T.5
Retzlaff, S.6
-
57
-
-
0031937076
-
G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator
-
Bais C, Santomasso B, Coso O, Arvanitakis L, Raaka EG, Gutkind JS et al. G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator. Nature 1998; 391: 86-89.
-
(1998)
Nature
, vol.391
, pp. 86-89
-
-
Bais, C.1
Santomasso, B.2
Coso, O.3
Arvanitakis, L.4
Raaka, E.G.5
Gutkind, J.S.6
-
58
-
-
11844301690
-
Role for Raf in the entry of viruses associated with AIDS
-
Whitman AG, Hamden KH, Ford PW, McCubrey JA, Akula SM. Role for Raf in the entry of viruses associated with AIDS. Int J Oncol 2004; 25: 469-480.
-
(2004)
Int. J. Oncol.
, vol.25
, pp. 469-480
-
-
Whitman, A.G.1
Hamden, K.H.2
Ford, P.W.3
McCubrey, J.A.4
Akula, S.M.5
-
59
-
-
0141502211
-
Differential effects of kinase cascade inhibitors on neoplastic and cytokine-mediated cell proliferation
-
Shelton JG, Moye PW, Steelman LS, Blalock WL, Lee JT, Franklin RA et al. Differential effects of kinase cascade inhibitors on neoplastic and cytokine-mediated cell proliferation. Leukemia 2003; 17: 1765-1782.
-
(2003)
Leukemia
, vol.17
, pp. 1765-1782
-
-
Shelton, J.G.1
Moye, P.W.2
Steelman, L.S.3
Blalock, W.L.4
Lee, J.T.5
Franklin, R.A.6
-
60
-
-
0031761118
-
Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells
-
McCubrey JA, Steelman LS, Hoyle PE, Blalock WL, Weinstein-Oppenheimer C, Franklin RA et al. Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells. Leukemia 1998; 12: 1903-1929.
-
(1998)
Leukemia
, vol.12
, pp. 1903-1929
-
-
McCubrey, J.A.1
Steelman, L.S.2
Hoyle, P.E.3
Blalock, W.L.4
Weinstein-Oppenheimer, C.5
Franklin, R.A.6
-
61
-
-
0035019189
-
Effects of inducible MEK1 activation on the cytokine dependency of lymphoid cells
-
Blalock WL, Pearce M, Chang F, Lee JT, Pohnert SC, Burrows C et al. Effects of inducible MEK1 activation on the cytokine dependency of lymphoid cells. Leukemia 2001; 15: 794-807.
-
(2001)
Leukemia
, vol.15
, pp. 794-807
-
-
Blalock, W.L.1
Pearce, M.2
Chang, F.3
Lee, J.T.4
Pohnert, S.C.5
Burrows, C.6
-
62
-
-
0034606671
-
Inflammatory cytokines and the reactivation of Kaposi's sarcoma associated herpesvirus lytic replication
-
Chang J, Renne R, Dittmer D, Ganem D. Inflammatory cytokines and the reactivation of Kaposi's sarcoma associated herpesvirus lytic replication. Virology 2000; 266: 17-25.
-
(2000)
Virology
, vol.266
, pp. 17-25
-
-
Chang, J.1
Renne, R.2
Dittmer, D.3
Ganem, D.4
-
63
-
-
0031604401
-
Human herpesvirus 8 and its role in the genesis of Kaposi's sarcoma
-
Ganem D. Human herpesvirus 8 and its role in the genesis of Kaposi's sarcoma. Curr Clin Top Infect Dis 1998; 18: 237-251.
-
(1998)
Curr. Clin. Top Infect. Dis.
, vol.18
, pp. 237-251
-
-
Ganem, D.1
-
64
-
-
0034762203
-
The Raf/MEK/ERK pathway: New concepts of activation
-
Peyssonnaux C, Eychene A. The Raf/MEK/ERK pathway: new concepts of activation. Biol Cell 2001; 1-2: 53-62.
-
(2001)
Biol. Cell
, vol.1-2
, pp. 53-62
-
-
Peyssonnaux, C.1
Eychene, A.2
-
65
-
-
0036983115
-
The Ras-Raf-MEK-ERK pathway in the treatment of cancer
-
Hilger RA, Scheulen ME, Strumberg D. The Ras-Raf-MEK-ERK pathway in the treatment of cancer. Onkologie 2002; 25: 511-518.
-
(2002)
Onkologie
, vol.25
, pp. 511-518
-
-
Hilger, R.A.1
Scheulen, M.E.2
Strumberg, D.3
-
66
-
-
0343492260
-
Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus
-
Rapp UR, Goldsborough MD, Mark GE, Bonner TI, Groffen J, Reynolds Jr FH et al. Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus. Proc Natl Acad Sci USA 1983; 80: 4218-4222.
-
(1983)
Proc. Natl. Acad. Sci. USA
, vol.80
, pp. 4218-4222
-
-
Rapp, U.R.1
Goldsborough, M.D.2
Mark, G.E.3
Bonner, T.I.4
Groffen, J.5
Reynolds Jr., F.H.6
-
67
-
-
0024376173
-
Ras oncogenes in human cancer: A review
-
Bos JL. Ras oncogenes in human cancer: a review. Cancer Res 1989; 49: 4682-4689.
-
(1989)
Cancer Res.
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
68
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S et al. Mutations of the BRAF gene in human cancer. Nature 2002; 417: 949-953.
-
(2002)
Nature
, vol.417
, pp. 949-953
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
Stephens, P.4
Edkins, S.5
Clegg, S.6
-
70
-
-
0038697566
-
Raf proteins and cancer: B-Raf is identified as a mutational target
-
Mercer KE, Pritchard CA. Raf proteins and cancer: B-Raf is identified as a mutational target. Biochim Biophys Acta 2003; 1653: 25-40.
-
(2003)
Biochim. Biophys. Acta
, vol.1653
, pp. 25-40
-
-
Mercer, K.E.1
Pritchard, C.A.2
-
71
-
-
1342301559
-
Conferring specificity on the ubiquitous Raf/MEK signaling pathway
-
O'Neill E, Kolch W. Conferring specificity on the ubiquitous Raf/MEK signaling pathway. Br J Cancer 2004; 90: 283-288.
-
(2004)
Br. J. Cancer
, vol.90
, pp. 283-288
-
-
O'Neill, E.1
Kolch, W.2
-
72
-
-
0347626041
-
A JC virus-induced signal is required for infection of glial cells by a clathrin- and eps15-dependent pathway
-
Querbes W, Benmerah A, Tosoni D, Di Fiore PP, Atwood WJ. A JC virus-induced signal is required for infection of glial cells by a clathrin- and eps15-dependent pathway. J Virol 2004; 78: 250-256.
-
(2004)
J. Virol.
, vol.78
, pp. 250-256
-
-
Querbes, W.1
Benmerah, A.2
Tosoni, D.3
Di Fiore, P.P.4
Atwood, W.J.5
-
73
-
-
0042265526
-
Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus
-
Wang X, Huong SM, Chiu ME, Raab-Traub N, Huang ES. Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus. Nature 2003; 424: 456-461.
-
(2003)
Nature
, vol.424
, pp. 456-461
-
-
Wang, X.1
Huong, S.M.2
Chiu, M.E.3
Raab-Traub, N.4
Huang, E.S.5
-
74
-
-
1842536029
-
Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 envelope glycoprotein gB induces the integrin-dependent focal adhesion kinase-Src-phosphatidylinositol 3-kinase-rho GTPase signal pathways and cytoskeletal rearrangements
-
Sharma-Walia N, Naranatt PP, Krishnan HH, Zeng L, Chandran B. Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 envelope glycoprotein gB induces the integrin-dependent focal adhesion kinase-Src-phosphatidylinositol 3-kinase-rho GTPase signal pathways and cytoskeletal rearrangements. J Virol 2004; 78: 4207-4223.
-
(2004)
J. Virol.
, vol.78
, pp. 4207-4223
-
-
Sharma-Walia, N.1
Naranatt, P.P.2
Krishnan, H.H.3
Zeng, L.4
Chandran, B.5
-
75
-
-
3142757400
-
Raf promotes human herpesvirus-8 (HHV-8/KSHV) infection
-
Akula SM, Ford PW, Whitman AG, Hamden KE, Shelton JG, McCubrey JA. Raf promotes human herpesvirus-8 (HHV-8/KSHV) infection. Oncogene 2004; 23: 5227-5241.
-
(2004)
Oncogene
, vol.23
, pp. 5227-5241
-
-
Akula, S.M.1
Ford, P.W.2
Whitman, A.G.3
Hamden, K.E.4
Shelton, J.G.5
McCubrey, J.A.6
-
76
-
-
0034076367
-
Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by MEK1-dependent mechanism
-
Hoyle PE, Moye PW, Steelman LS, Blalock WL, Franklin RA, Pearce M et al. Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by MEK1-dependent mechanism. Leukemia 2000; 14: 642-656.
-
(2000)
Leukemia
, vol.14
, pp. 642-656
-
-
Hoyle, P.E.1
Moye, P.W.2
Steelman, L.S.3
Blalock, W.L.4
Franklin, R.A.5
Pearce, M.6
-
78
-
-
8644291553
-
Raf induced vascular endothelial growth factor augments Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) infection
-
(in press)
-
Hamden KH, Ford PW, Whitman AG, Dyson OF, McCubrey JA, Akula SM. Raf induced vascular endothelial growth factor augments Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) infection. J Virol (in press).
-
J. Virol.
-
-
Hamden, K.H.1
Ford, P.W.2
Whitman, A.G.3
Dyson, O.F.4
McCubrey, J.A.5
Akula, S.M.6
-
80
-
-
2942534219
-
The CD40-induced signaling pathway in endothelial cells resulting in the overexpression of vascular endothelial growth factor involves Ras and phosphatidylinositol 3-kinase
-
Flaxenburg JA, Melter M, Lapchak PH, Briscoe DM, Pal S. The CD40-induced signaling pathway in endothelial cells resulting in the overexpression of vascular endothelial growth factor involves Ras and phosphatidylinositol 3-kinase. J Immun 2004; 172: 7503-7509.
-
(2004)
J. Immun.
, vol.172
, pp. 7503-7509
-
-
Flaxenburg, J.A.1
Melter, M.2
Lapchak, P.H.3
Briscoe, D.M.4
Pal, S.5
-
81
-
-
0242636164
-
Growing and shaping the vascular tree: Multiple roles for VEGF
-
Ruhrberg C. Growing and shaping the vascular tree: multiple roles for VEGF. BioEssays 2003; 25: 1052-1060.
-
(2003)
BioEssays
, vol.25
, pp. 1052-1060
-
-
Ruhrberg, C.1
-
82
-
-
2542629644
-
Expression of VEGF isoforms by epiphyseal chondrocytes during low-oxygen tension is HIF-1 alpha dependent
-
Cramer T, Schipani E, Johnson RS, Swoboda B, Pfander D. Expression of VEGF isoforms by epiphyseal chondrocytes during low-oxygen tension is HIF-1 alpha dependent. Osteoarthr Cartilage 2004; 12 433-439.
-
(2004)
Osteoarthr. Cartilage
, vol.12
, pp. 433-439
-
-
Cramer, T.1
Schipani, E.2
Johnson, R.S.3
Swoboda, B.4
Pfander, D.5
-
83
-
-
0346365282
-
All three receptors for vascular endothelial growth factor (VEGF) are expressed on B-chronic lymphocytic leukemia (CLL) cells
-
Bairey O, Boycov O, Kaganovsky E, Zimra Y, Shaklai M, Rabizadeh E. All three receptors for vascular endothelial growth factor (VEGF) are expressed on B-chronic lymphocytic leukemia (CLL) cells. Leukemia Res 2004; 28: 243-248.
-
(2004)
Leukemia Res.
, vol.28
, pp. 243-248
-
-
Bairey, O.1
Boycov, O.2
Kaganovsky, E.3
Zimra, Y.4
Shaklai, M.5
Rabizadeh, E.6
-
85
-
-
2942590261
-
Vascular endothelial growth factor as a target for anticancer therapy
-
Ferrara N. Vascular endothelial growth factor as a target for anticancer therapy. Oncologist 2004; 9: 2-10.
-
(2004)
Oncologist
, vol.9
, pp. 2-10
-
-
Ferrara, N.1
-
87
-
-
0038514919
-
Inhibition of vascular endothelial growth factor in the treatment of colorectal cancer
-
Fernando NH, Herwitz HI. Inhibition of vascular endothelial growth factor in the treatment of colorectal cancer. Semin Oncol 2003; 30: S39-S50.
-
(2003)
Semin. Oncol.
, vol.30
-
-
Fernando, N.H.1
Herwitz, H.I.2
-
88
-
-
12144290647
-
Advances in the structural biology, design and clinical development of VEGF-R kinase inhibitors for the treatment of angiogenesis
-
Manley PW, Bold G, Brüggen J, Fendrich G, Furet P, Mestan J et al. Advances in the structural biology, design and clinical development of VEGF-R kinase inhibitors for the treatment of angiogenesis. Biochem Biophys Acta 2004; 1697: 17-27.
-
(2004)
Biochem. Biophys. Acta
, vol.1697
, pp. 17-27
-
-
Manley, P.W.1
Bold, G.2
Brüggen, J.3
Fendrich, G.4
Furet, P.5
Mestan, J.6
-
89
-
-
0037468875
-
Discovery of 5-[5-flouro-2-oxo-1,2-dihydroin-dol-(3Z)-ylidenemethyl] -2,4-dimethyl-1H-pyrrole-3-carboxylic Acid (2-diethylaminothyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor receptor tyrosine kinase
-
Sun L, Liang C, Shirazian S, Zhou Y, Miller T, Cui J et al. Discovery of 5-[5-flouro-2-oxo-1,2-dihydroin-dol-(3Z)-ylidenemethyl]-2,4-dimethyl-1H -pyrrole-3-carboxylic Acid (2-diethylaminothyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor receptor tyrosine kinase. J Med Chem 2003; 46: 1116-1119.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 1116-1119
-
-
Sun, L.1
Liang, C.2
Shirazian, S.3
Zhou, Y.4
Miller, T.5
Cui, J.6
-
90
-
-
0037075812
-
Novel 4-anilinoquinazolines with C-7 basic side chains: Design and structure activity relationship of a series of potent, orally active, VEGF receptor tyrosine kinase inhibitors
-
Hennequin LF, Stokes ESE, Thomas AP, Johnstone C, Ple PA, Ogilvie DJ et al. Novel 4-anilinoquinazolines with C-7 basic side chains: design and structure activity relationship of a series of potent, orally active, VEGF receptor tyrosine kinase inhibitors. J Med Chem 2002; 45: 1300-1312.
-
(2002)
J. Med. Chem.
, vol.45
, pp. 1300-1312
-
-
Hennequin, L.F.1
Stokes, E.S.E.2
Thomas, A.P.3
Johnstone, C.4
Ple, P.A.5
Ogilvie, D.J.6
-
91
-
-
0033947625
-
New anilinophthalazines as potent and orally well absorbed inhibitors of the VEGF receptor tyrosine kinases useful as antagonists of tumor-driven angiogenesis
-
Bold G, Altmann K-H, Frei J, Lang M, Manley PW, Traxler P et al. New anilinophthalazines as potent and orally well absorbed inhibitors of the VEGF receptor tyrosine kinases useful as antagonists of tumor-driven angiogenesis. J Med Chem 2000; 43: 2310-2323.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 2310-2323
-
-
Bold, G.1
Altmann, K.-H.2
Frei, J.3
Lang, M.4
Manley, P.W.5
Traxler, P.6
-
94
-
-
2442676378
-
Peptidoglycan induces nuclear factor-kappaB activation and cyclooxygenase-2 expression via Ras, Raf-1, and ERK in RAW 264-7 macrophages
-
Chen BC, Chang YS, Kang JC, Hsu MJ, Sheu JR, Chen TL et al. Peptidoglycan induces nuclear factor-kappaB activation and cyclooxygenase-2 expression via Ras, Raf-1, and ERK in RAW 264-7 macrophages. J Biol Chem 2004; 279: 20889-20897.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 20889-20897
-
-
Chen, B.C.1
Chang, Y.S.2
Kang, J.C.3
Hsu, M.J.4
Sheu, J.R.5
Chen, T.L.6
-
95
-
-
0005318501
-
Effect of SB 203580 on the activity of c-Raf in vitro and in vivo
-
Hall-Jackson CA, Goedert M, Hedge P, Cohen P. Effect of SB 203580 on the activity of c-Raf in vitro and in vivo. Oncogene 1999; 18: 2047-2054.
-
(1999)
Oncogene
, vol.18
, pp. 2047-2054
-
-
Hall-Jackson, C.A.1
Goedert, M.2
Hedge, P.3
Cohen, P.4
-
96
-
-
0033986112
-
Anticancer drug targets: Growth factors and growth factor signaling
-
Gibbs JB. Anticancer drug targets: growth factors and growth factor signaling. J Clin Invest 2000; 105: 9-13.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 9-13
-
-
Gibbs, J.B.1
-
97
-
-
0034026007
-
A phase I trial of c-Raf kinase antisense oligonucleotide ISIS 5132 administered as a continuous intravenous infusion in patients with advanced cancer
-
Cunningham CC, Holmlund JT, Schiller JH, Geary RS, Kwoh TJ, Dorr A et al. A phase I trial of c-Raf kinase antisense oligonucleotide ISIS 5132 administered as a continuous intravenous infusion in patients with advanced cancer. Clin Cancer Res 2000; 6: 1626-1631.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 1626-1631
-
-
Cunningham, C.C.1
Holmlund, J.T.2
Schiller, J.H.3
Geary, R.S.4
Kwoh, T.J.5
Dorr, A.6
-
98
-
-
0242468891
-
CI-1040 (PD184352), a targeted signal transduction inhibitor of MEK (MAPKK)
-
Allen LF, Sebolt-Leopold J, Meyer MB. CI-1040 (PD184352), a targeted signal transduction inhibitor of MEK (MAPKK). Semin Oncol 2003; 30: 105-116.
-
(2003)
Semin. Oncol.
, vol.30
, pp. 105-116
-
-
Allen, L.F.1
Sebolt-Leopold, J.2
Meyer, M.B.3
-
99
-
-
3042838587
-
Use of mitogenic cascade blockers for treatment of C-Raf induced lung adenoma in vivo: CI-1040 strongly reduces growth and improves lung structure
-
Kramer BW, Goetz R, Rapp UR. Use of mitogenic cascade blockers for treatment of C-Raf induced lung adenoma in vivo: CI-1040 strongly reduces growth and improves lung structure. BMC Cancer 2004; 4: 24.
-
(2004)
BMC Cancer
, vol.4
, pp. 24
-
-
Kramer, B.W.1
Goetz, R.2
Rapp, U.R.3
-
100
-
-
1542571327
-
Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi sarcoma pathogenesis
-
Grundhoff A, Ganem D. Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi sarcoma pathogenesis. J Clin Invest 2004; 113: 124-136.
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 124-136
-
-
Grundhoff, A.1
Ganem, D.2
-
101
-
-
0030789149
-
Human herpesvirus 8 DNA sequences in CD8+ T cells
-
Sirianni MC, Vincenzi L, Topino S, Scala E, Angeloni A, Gonnella R et al. Human herpesvirus 8 DNA sequences in CD8+ T cells. J Infect Dis 1997; 176: 541.
-
(1997)
J. Infect. Dis.
, vol.176
, pp. 541
-
-
Sirianni, M.C.1
Vincenzi, L.2
Topino, S.3
Scala, E.4
Angeloni, A.5
Gonnella, R.6
|