-
1
-
-
0028929803
-
Angiogenesis in cancer, rheumatoid and other disease
-
Folkman J: Angiogenesis in cancer, rheumatoid and other disease. Nat Med 1:27-31, 1995
-
(1995)
Nat Med
, vol.1
, pp. 27-31
-
-
Folkman, J.1
-
2
-
-
0023157363
-
Angiogenic factors
-
Folkman J: Angiogenic factors. Science 235:442-447, 1987
-
(1987)
Science
, vol.235
, pp. 442-447
-
-
Folkman, J.1
-
3
-
-
0002418099
-
Vascular diseases
-
Garner AKG (ed). New York, NY, Dekker
-
Garner A: Vascular diseases, in Garner AKG (ed): Pathobiology of Ocular Diseases. New York, NY, Dekker, 1994, pp 1625-1710
-
(1994)
Pathobiology of Ocular Diseases
, pp. 1625-1710
-
-
Garner, A.1
-
4
-
-
0025141337
-
What is the evidence that tumors are angiogenesis dependent?
-
Folkman J: What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 82:4-6, 1990
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 4-6
-
-
Folkman, J.1
-
5
-
-
84959830787
-
Vascular reactions of normal and malignant tumors in vivo: I. Vascular reactions of mice to wounds and to normal and neoplastic transplants
-
Algire G, Chalkely H, Legallais F, et al: Vascular reactions of normal and malignant tumors in vivo: I. Vascular reactions of mice to wounds and to normal and neoplastic transplants. J Natl Cancer Inst 6:73-85, 1945
-
(1945)
J Natl Cancer Inst
, vol.6
, pp. 73-85
-
-
Algire, G.1
Chalkely, H.2
Legallais, F.3
-
6
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implication
-
Folkman J: Tumor angiogenesis: Therapeutic implication. N Engl J Med 285:1182-1186, 1971
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
7
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
Hanahan D, Folkman J: Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86: 353-364, 1996
-
(1996)
Cell
, vol.86
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
8
-
-
0032852528
-
Molecular and biological properties of vascular endothelial growth factor
-
Ferrara N: Molecular and biological properties of vascular endothelial growth factor. J Mol Med 77:527-543, 1999
-
(1999)
J Mol Med
, vol.77
, pp. 527-543
-
-
Ferrara, N.1
-
9
-
-
0028470454
-
Barriers to drug delivery in solid tumors
-
Jain R: Barriers to drug delivery in solid tumors. Sci Am 271:58-65, 1994
-
(1994)
Sci Am
, vol.271
, pp. 58-65
-
-
Jain, R.1
-
10
-
-
0025717523
-
Inhibition of tumor angiogenesis as a strategy to circumvent acquired resistance to anti-cancer therapeutic agents
-
Kerbel R: Inhibition of tumor angiogenesis as a strategy to circumvent acquired resistance to anti-cancer therapeutic agents. Bioessays 13:31-36, 1991
-
(1991)
Bioessays
, vol.13
, pp. 31-36
-
-
Kerbel, R.1
-
11
-
-
0026486664
-
Antiangiogenic agents potentiate cytotoxic cancer therapies against primary and metastatic disease
-
Teicher B, Sotomayor E, Huang Z, et al: Antiangiogenic agents potentiate cytotoxic cancer therapies against primary and metastatic disease. Cancer Res 52:6702-6704, 1992
-
(1992)
Cancer Res
, vol.52
, pp. 6702-6704
-
-
Teicher, B.1
Sotomayor, E.2
Huang, Z.3
-
12
-
-
0032829104
-
Tumor angiogenesis - New drugs on the block
-
Brower V: Tumor angiogenesis - New drugs on the block. Nat Biotechnol 17:963-968, 1999
-
(1999)
Nat Biotechnol
, vol.17
, pp. 963-968
-
-
Brower, V.1
-
13
-
-
0028941001
-
Vascular endothelial growth factor in human glioma cell lines: Induced secretion by EGF, PDGF-BB, bFGF
-
Tsai J, Goldman C, Gillespie G: Vascular endothelial growth factor in human glioma cell lines: Induced secretion by EGF, PDGF-BB, bFGF. J Neurosurg 82: 864-873, 1995
-
(1995)
J Neurosurg
, vol.82
, pp. 864-873
-
-
Tsai, J.1
Goldman, C.2
Gillespie, G.3
-
14
-
-
0032170035
-
Regulation of vascular endothelial growth factor expression in human colon cancer by insulin-like growth factor-I
-
Akagi Y, Liu W, Zebrowski B, et al: Regulation of vascular endothelial growth factor expression in human colon cancer by insulin-like growth factor-I. Cancer Res 58:4008-4014, 1998
-
(1998)
Cancer Res
, vol.58
, pp. 4008-4014
-
-
Akagi, Y.1
Liu, W.2
Zebrowski, B.3
-
15
-
-
0032987569
-
Regulation of vascular endothelial growth factor expression in human colon cancer by interleukin- 1 beta
-
Akagi Y, Liu W, Xie K, et al: Regulation of vascular endothelial growth factor expression in human colon cancer by interleukin-1 beta. Br J Cancer 80: 1506-1511, 1999
-
(1999)
Br J Cancer
, vol.80
, pp. 1506-1511
-
-
Akagi, Y.1
Liu, W.2
Xie, K.3
-
16
-
-
0030046481
-
Interleukin 6 induces the expression of vascular endothelial growth factor
-
Cohen T, Nahari D, Cerem L, et al: Interleukin 6 induces the expression of vascular endothelial growth factor. J Biol Chem 271:736-741, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 736-741
-
-
Cohen, T.1
Nahari, D.2
Cerem, L.3
-
17
-
-
0030066455
-
Platelet-derived growth factor-B/v-sis confers a tumorigenic and metastatic phenotype to human T 98G glioblastoma cells
-
Potapova O, Fakhari H, Baird S, et al: Platelet-derived growth factor-B/v-sis confers a tumorigenic and metastatic phenotype to human T98G glioblastoma cells. Cancer Res 56:280-286, 1996
-
(1996)
Cancer Res
, vol.56
, pp. 280-286
-
-
Potapova, O.1
Fakhari, H.2
Baird, S.3
-
18
-
-
0029039195
-
Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia
-
Levy A, Levy NC, Wegner S, et al: Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia. J Biol Chem 279:13333-13340, 1995
-
(1995)
J Biol Chem
, vol.279
, pp. 13333-13340
-
-
Levy, A.1
Levy, N.C.2
Wegner, S.3
-
19
-
-
0026485002
-
Vascular endothelial cell growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
-
Shweiki D, Itin A, Soffer D, et al: Vascular endothelial cell growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359:843-845, 1992
-
(1992)
Nature
, vol.359
, pp. 843-845
-
-
Shweiki, D.1
Itin, A.2
Soffer, D.3
-
20
-
-
0028870050
-
Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implication for tumor angiogenesis
-
Shweiki D, Neeman M, Itin A, et al: Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implication for tumor angiogenesis. Proc Natl Acad Sci U S A 92:768-772, 1995
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 768-772
-
-
Shweiki, D.1
Neeman, M.2
Itin, A.3
-
21
-
-
0033590207
-
The role of cyclooxygenases in inflammation, cancer and development
-
Williams C, Mann M, DuBois R: The role of cyclooxygenases in inflammation, cancer and development. Oncogene 18:7908-7916, 1999
-
(1999)
Oncogene
, vol.18
, pp. 7908-7916
-
-
Williams, C.1
Mann, M.2
DuBois, R.3
-
22
-
-
0003504049
-
Cyclooxygenase regulates angiogenesis induced by colon cancer cells
-
Tsujii M, Kawano S, Tsuiji S, et al: Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cancer 93:705-716, 1998
-
(1998)
Cancer
, vol.93
, pp. 705-716
-
-
Tsujii, M.1
Kawano, S.2
Tsuiji, S.3
-
23
-
-
0034161878
-
Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors
-
Masferrer J, Leahy K, Koki A, et al: Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors. Cancer Res 60:1306-1311, 2000
-
(2000)
Cancer Res
, vol.60
, pp. 1306-1311
-
-
Masferrer, J.1
Leahy, K.2
Koki, A.3
-
25
-
-
0024384470
-
Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells
-
Ferrara N, Henzel W: Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem Biophys Res Commun 161:851-858, 1989
-
(1989)
Biochem Biophys Res Commun
, vol.161
, pp. 851-858
-
-
Ferrara, N.1
Henzel, W.2
-
26
-
-
0025999033
-
The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing
-
Tischer E, Mitchell R, Hartman T, et al: The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing. J Biol Chem 266:1459-1472, 1991
-
(1991)
J Biol Chem
, vol.266
, pp. 1459-1472
-
-
Tischer, E.1
Mitchell, R.2
Hartman, T.3
-
27
-
-
0027751890
-
The vascular endothelial growth factor (VEGF) isoforms: Differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF
-
Park J, Keller G, Ferrara N: The vascular endothelial growth factor (VEGF) isoforms: Differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF. Mol Biol Cell 4:1317-1326, 1993
-
(1993)
Mol Biol Cell
, vol.4
, pp. 1317-1326
-
-
Park, J.1
Keller, G.2
Ferrara, N.3
-
28
-
-
0029937679
-
The carboxyl-terminal domain (111-165) of vascular endothelial growth factor is critical for its mitogenic potency
-
Keyt B, Berleau L, Nguyen H: The carboxyl-terminal domain (111-165) of vascular endothelial growth factor is critical for its mitogenic potency. J Biol Chem 272:7788-7795, 1996
-
(1996)
J Biol Chem
, vol.272
, pp. 7788-7795
-
-
Keyt, B.1
Berleau, L.2
Nguyen, H.3
-
29
-
-
0024818355
-
Vascular endothelial growth factor is a secreted angiogenic mitogen
-
Leung D, Cachianes G, Kuang WJ, et al: Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246:1306-1309, 1989
-
(1989)
Science
, vol.246
, pp. 1306-1309
-
-
Leung, D.1
Cachianes, G.2
Kuang, W.J.3
-
30
-
-
0021111648
-
Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
-
Senger D, Galli S, Dvorak A, et al: Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 219:983-985, 1983
-
(1983)
Science
, vol.219
, pp. 983-985
-
-
Senger, D.1
Galli, S.2
Dvorak, A.3
-
31
-
-
0023610220
-
Fibrin containing gels induce angiogenesis. Implications for tumor stoma generation and wound healing
-
Dvorak H, Harvey V, Estrella P, et al: Fibrin containing gels induce angiogenesis. Implications for tumor stoma generation and wound healing. Lab Invest 57:673-686, 1987
-
(1987)
Lab Invest
, vol.57
, pp. 673-686
-
-
Dvorak, H.1
Harvey, V.2
Estrella, P.3
-
32
-
-
0022891340
-
Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
-
Dvorak H: Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing. N Engl J Med 315:1650-1659, 1986
-
(1986)
N Engl J Med
, vol.315
, pp. 1650-1659
-
-
Dvorak, H.1
-
33
-
-
0031834239
-
A plasticity window for blood vessel remodeling is defined by pericyte coverage of the preformed endothelial networks and is regulated by PDGF-B and VEGF
-
Benjamin L, Hemo I, Keshet E: A plasticity window for blood vessel remodeling is defined by pericyte coverage of the preformed endothelial networks and is regulated by PDGF-B and VEGF. Development 125:1591-1598, 1998
-
(1998)
Development
, vol.125
, pp. 1591-1598
-
-
Benjamin, L.1
Hemo, I.2
Keshet, E.3
-
34
-
-
0032952010
-
Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal
-
Benjamin L, Golijanin D, Itin A, et al: Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal. J Clin Invest 103:159-165, 1999
-
(1999)
J Clin Invest
, vol.103
, pp. 159-165
-
-
Benjamin, L.1
Golijanin, D.2
Itin, A.3
-
35
-
-
0032557564
-
Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and Al in vascular endothelial cells
-
Gerber H, Dixit V, Ferrara N: Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and Al in vascular endothelial cells. J Biol Chem 273: 13313-13316, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 13313-13316
-
-
Gerber, H.1
Dixit, V.2
Ferrara, N.3
-
36
-
-
0028095127
-
Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin
-
Goldberg M, Schneider T: Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin. J Biol Chem 269:4355-4361, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 4355-4361
-
-
Goldberg, M.1
Schneider, T.2
-
37
-
-
0026572345
-
The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor
-
de Vries C, Escobedo JA, Ueno H, et al: The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 255:989-991, 1992
-
(1992)
Science
, vol.255
, pp. 989-991
-
-
De Vries, C.1
Escobedo, J.A.2
Ueno, H.3
-
38
-
-
0026702970
-
Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor
-
Terman BI, Dougher-Vermazen M, Carrion ME, et al: Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor. Biochem Biophys Res Commun 187:1579-1586, 1992
-
(1992)
Biochem Biophys Res Commun
, vol.187
, pp. 1579-1586
-
-
Terman, B.I.1
Dougher-Vermazen, M.2
Carrion, M.E.3
-
39
-
-
0033083962
-
Expression of vascular endothelial growth factor (VEGF) and its receptors in hematopoietic malignancies
-
Bellamy W, Richter L, Frutiger Y, et al: Expression of vascular endothelial growth factor (VEGF) and its receptors in hematopoietic malignancies. Cancer Res 59:728-733, 1999
-
(1999)
Cancer Res
, vol.59
, pp. 728-733
-
-
Bellamy, W.1
Richter, L.2
Frutiger, Y.3
-
40
-
-
0032838197
-
Expression of vascular endothelial growth factor receptors in human prostate cancer
-
Ferrer F, Miller L, Lindquist R, et al: Expression of vascular endothelial growth factor receptors in human prostate cancer. Urology 54:567-572, 1999
-
(1999)
Urology
, vol.54
, pp. 567-572
-
-
Ferrer, F.1
Miller, L.2
Lindquist, R.3
-
41
-
-
0035068834
-
Vascular endothelial growth factor is an autocrine growth factor in human malignant mesothelioma
-
Strizzi L, Catalano A, Vianale G, et al: Vascular endothelial growth factor is an autocrine growth factor in human malignant mesothelioma. J Pathol 193:468-475, 2001
-
(2001)
J Pathol
, vol.193
, pp. 468-475
-
-
Strizzi, L.1
Catalano, A.2
Vianale, G.3
-
42
-
-
0029006696
-
Failure of blood-island formation and vasculogenesis in Flk-1 deficient mice
-
Shalaby F, Rossant J, Yamaguchi T, et al: Failure of blood-island formation and vasculogenesis in Flk-1 deficient mice. Nature 376:62-66, 1995
-
(1995)
Nature
, vol.376
, pp. 62-66
-
-
Shalaby, F.1
Rossant, J.2
Yamaguchi, T.3
-
43
-
-
0029021660
-
Role of Flt- 1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
-
Fong G, Rossant J, Gertsenstein M, et al: Role of Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 376:66-70, 1995
-
(1995)
Nature
, vol.376
, pp. 66-70
-
-
Fong, G.1
Rossant, J.2
Gertsenstein, M.3
-
44
-
-
0034069028
-
Antitumor and antimetastatic activity of ribozymes targeting the messenger RNA of vascular endothelial growth factor receptors
-
Pavco P, Bouhana K, Gallegos A, et al: Antitumor and antimetastatic activity of ribozymes targeting the messenger RNA of vascular endothelial growth factor receptors. Clin Cancer Res 6:2094-2103, 2000
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2094-2103
-
-
Pavco, P.1
Bouhana, K.2
Gallegos, A.3
-
45
-
-
0030973506
-
Hyperplasia of lymphatic vessels in VEGF-C transgenic mice
-
Jeltsch M, Kaipainen A, Joukov V, et al: Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Science 276: 1423-1425, 1997
-
(1997)
Science
, vol.276
, pp. 1423-1425
-
-
Jeltsch, M.1
Kaipainen, A.2
Joukov, V.3
-
46
-
-
0032549799
-
Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
-
Soker S, Takashima S, Miao HQ, et al: Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92:735-745, 1998
-
(1998)
Cell
, vol.92
, pp. 735-745
-
-
Soker, S.1
Takashima, S.2
Miao, H.Q.3
-
47
-
-
0032544686
-
Tumor induction of VEGF promoter activity in stromal cells
-
Fukumura D, Xavier R, Sugiura T, et al: Tumor induction of VEGF promoter activity in stromal cells. Cell 94:715-725, 1998
-
(1998)
Cell
, vol.94
, pp. 715-725
-
-
Fukumura, D.1
Xavier, R.2
Sugiura, T.3
-
48
-
-
0035352721
-
Angiogenesis: Pathological prognostic and growth-factor pathways and their link to trial design and anticancer drugs
-
Fox S, Giampietro G, Harris A: Angiogenesis: Pathological prognostic and growth-factor pathways and their link to trial design and anticancer drugs. Lancet Oncol 2:278-289, 2001
-
(2001)
Lancet Oncol
, vol.2
, pp. 278-289
-
-
Fox, S.1
Giampietro, G.2
Harris, A.3
-
49
-
-
0031032073
-
Prognostic significance of vascular endothelial growth factor protein in nodenegative breast carcinoma
-
Gasparini G, Toi, M, Gion M, et al: Prognostic significance of vascular endothelial growth factor protein in nodenegative breast carcinoma. J Natl Cancer Inst 89:139-147, 1997
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 139-147
-
-
Gasparini, G.1
Toi, M.2
Gion, M.3
-
50
-
-
1842415455
-
Vessel counts and expression of vascular endothelial growth factor as prognostic factors in node-negative colon cancer
-
Takahashi Y, Tucker S, Kitadai Y, et al: Vessel counts and expression of vascular endothelial growth factor as prognostic factors in node-negative colon cancer. Arch Surg 132: 541-546, 1997
-
(1997)
Arch Surg
, vol.132
, pp. 541-546
-
-
Takahashi, Y.1
Tucker, S.2
Kitadai, Y.3
-
51
-
-
0031965353
-
Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor
-
Lin P, Sankar S, Shan S: Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor. Cell Growth Differ 9:49-58, 1998
-
(1998)
Cell Growth Differ
, vol.9
, pp. 49-58
-
-
Lin, P.1
Sankar, S.2
Shan, S.3
-
52
-
-
0032559040
-
Novel peptides selected to bind vascular endothelial growth factor target the receptor-binding site
-
Fairbrother W, Christinger H, Cochran A: Novel peptides selected to bind vascular endothelial growth factor target the receptor-binding site. Biochem 37:17754-17764, 1998
-
(1998)
Biochem
, vol.37
, pp. 17754-17764
-
-
Fairbrother, W.1
Christinger, H.2
Cochran, A.3
-
53
-
-
12244277954
-
Development of SU5416, a selective small molecule inhibitor of VEGF receptor tyrosine kinase activity, as an anti-angiogenesis agent
-
Mendel DB, Laird AD, Smolich BD, et al: Development of SU5416, a selective small molecule inhibitor of VEGF receptor tyrosine kinase activity, as an anti-angiogenesis agent. Anticancer Drug Des 15:29-41, 2000
-
(2000)
Anticancer Drug Des
, vol.15
, pp. 29-41
-
-
Mendel, D.B.1
Laird, A.D.2
Smolich, B.D.3
-
54
-
-
0026708632
-
The vascular endothelial growth factor proteins: Identification of biologically relevant regions by neutralizing monoclonal antibodies
-
Kim K, Li B, Houck K: The vascular endothelial growth factor proteins: Identification of biologically relevant regions by neutralizing monoclonal antibodies. Growth Factors 7:53-64, 1992
-
(1992)
Growth Factors
, vol.7
, pp. 53-64
-
-
Kim, K.1
Li, B.2
Houck, K.3
-
55
-
-
0030856731
-
Humanization of anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
-
Presto L, Chen H, O'Connor S: Humanization of anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res 57: 4593-4599, 1997
-
(1997)
Cancer Res
, vol.57
, pp. 4593-4599
-
-
Presto, L.1
Chen, H.2
O'Connor, S.3
-
56
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumor growth in vivo
-
Kim K, Li B, Winner J: Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumor growth in vivo. Nature 362:841-844, 1993
-
(1993)
Nature
, vol.362
, pp. 841-844
-
-
Kim, K.1
Li, B.2
Winner, J.3
-
57
-
-
0028935608
-
Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis
-
Warren R, Yaun H, Malti M: Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis. J Clin Invest 95:1789-1797, 1995
-
(1995)
J Clin Invest
, vol.95
, pp. 1789-1797
-
-
Warren, R.1
Yaun, H.2
Malti, M.3
-
58
-
-
0028824336
-
Inhibition of tumor growth and metastasis by immunoneutralizing monoclonal antibody to human vascular endothelial growth factor/vascular permeability factor 121
-
Asano M, Ayako Y, Matsumoto T: Inhibition of tumor growth and metastasis by immunoneutralizing monoclonal antibody to human vascular endothelial growth factor/vascular permeability factor 121. Cancer Res 55:5296-5301, 1995
-
(1995)
Cancer Res
, vol.55
, pp. 5296-5301
-
-
Asano, M.1
Ayako, Y.2
Matsumoto, T.3
-
59
-
-
0030059075
-
Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth
-
Melnyk O, Shuman M, Kim K: Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth. Cancer Res 56:921-924, 1996
-
(1996)
Cancer Res
, vol.56
, pp. 921-924
-
-
Melnyk, O.1
Shuman, M.2
Kim, K.3
-
60
-
-
0031898292
-
Neutralizing anti-vascular endothelial growth factor antibody completely inhibits angiogenesis and growth of human prostate carcinoma micro tumors in vivo
-
Borgstrom P, Bourdon M, Hillan K: Neutralizing anti-vascular endothelial growth factor antibody completely inhibits angiogenesis and growth of human prostate carcinoma micro tumors in vivo. Prostate 35:1-10, 1998
-
(1998)
Prostate
, vol.35
, pp. 1-10
-
-
Borgstrom, P.1
Bourdon, M.2
Hillan, K.3
-
61
-
-
0034032882
-
Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer
-
Browder T, Butterfield C, Kräling B: Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer. Cancer Res 60:1878-1886, 2000
-
(2000)
Cancer Res
, vol.60
, pp. 1878-1886
-
-
Browder, T.1
Butterfield, C.2
Kräling, B.3
-
62
-
-
0026753046
-
The effects of 5-fluorouracil and mitomycin C on the corneal endothelium
-
Nuyts R, Pels E, Greve E: The effects of 5-fluorouracil and mitomycin C on the corneal endothelium. Curr Eye Res 11:565-570, 1992
-
(1992)
Curr Eye Res
, vol.11
, pp. 565-570
-
-
Nuyts, R.1
Pels, E.2
Greve, E.3
-
63
-
-
0029802685
-
The microtubule-affecting drug paclitaxel has antiangiogenic activity
-
Belotti D, Vergani V, Drudis T, et al: The microtubule-affecting drug paclitaxel has antiangiogenic activity. Clin Cancer Res 2:1843-1849, 1996
-
(1996)
Clin Cancer Res
, vol.2
, pp. 1843-1849
-
-
Belotti, D.1
Vergani, V.2
Drudis, T.3
-
64
-
-
0032956544
-
Antiangiogenic effects of camptothecin analogues 9-amino-20(S)-camptothecin, topotecan, and CPT-11 studied in the mouse cornea model
-
O'Leary J, Shapiro R, Ren C, et al: Antiangiogenic effects of camptothecin analogues 9-amino-20(S)-camptothecin, topotecan, and CPT-11 studied in the mouse cornea model. Clin Cancer Res 5:181-187, 1999
-
(1999)
Clin Cancer Res
, vol.5
, pp. 181-187
-
-
O'Leary, J.1
Shapiro, R.2
Ren, C.3
-
65
-
-
0000748868
-
The effect of antibody to vascular endothelial growth factor and cisplatin on the growth of lung tumors in nude mice. Proc Am Assoc
-
abstr 2906
-
Kabbinavar F, Wong J, Ayala R, et al: The effect of antibody to vascular endothelial growth factor and cisplatin on the growth of lung tumors in nude mice. Proc Am Assoc Cancer Res 36:488, 1995 (abstr 2906)
-
(1995)
Cancer Res
, vol.36
, pp. 488
-
-
Kabbinavar, F.1
Wong, J.2
Ayala, R.3
-
66
-
-
0032806309
-
Importance of VEGF for breast cancer angiogenesis in vivo: Implications from intravital microscopy of combination treatments with an anti-VEGF neutralizing monoclonal antibody and doxorubicin
-
Borgstom P, Gold D, Hillan K, et al: Importance of VEGF for breast cancer angiogenesis in vivo: Implications from intravital microscopy of combination treatments with an anti-VEGF neutralizing monoclonal antibody and doxorubicin. Anticancer Res 19:4203-4214, 1999
-
(1999)
Anticancer Res
, vol.19
, pp. 4203-4214
-
-
Borgstom, P.1
Gold, D.2
Hillan, K.3
-
67
-
-
0032962265
-
Preclinical pharmacokinetics, interspecies scaling, and tissue distribution of a humanized monoclonal antibody against vascular endothelial growth factor
-
Lin Y, Nguyen C, Mendoza J: Preclinical pharmacokinetics, interspecies scaling, and tissue distribution of a humanized monoclonal antibody against vascular endothelial growth factor. J Pharmacol Exp Ther 288:371-378, 1998
-
(1998)
J Pharmacol Exp Ther
, vol.288
, pp. 371-378
-
-
Lin, Y.1
Nguyen, C.2
Mendoza, J.3
-
68
-
-
0001123178
-
Phase I trial of recombinant humanized monoclonal anti-vascular endothelial growth factor (anti-vegf mab) in patients with metastatic cancer
-
abstr 809
-
Gordon MS, Talpaz M, Margolin K, et al: Phase I trial of recombinant humanized monoclonal anti-vascular endothelial growth factor (anti-vegf mab) in patients with metastatic cancer. Proc Am Soc Clin Oncol 17:210a, 1998 (abstr 809)
-
(1998)
Proc Am Soc Clin Oncol
, vol.17
-
-
Gordon, M.S.1
Talpaz, M.2
Margolin, K.3
-
69
-
-
0013405842
-
MRI evaluation of the effects of the vascular-targeting agent ZD6126 on tumor vasculature
-
abstr 440
-
DelProposto Z, LoRusso P, Latif Z, et al: MRI evaluation of the effects of the vascular-targeting agent ZD6126 on tumor vasculature. Proc Am Soc Clin Oncol 21:111a, 2002 (abstr 440)
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
-
-
DelProposto, Z.1
LoRusso, P.2
Latif, Z.3
-
70
-
-
0038599016
-
Clinical evaluation of the novel vascular-targeting agent, ZD6126: Assessment of toxicity and surrogate markers of vascular damage
-
abstr 439
-
Radema S, Beerepoot LV, Witteveen PO, et al: Clinical evaluation of the novel vascular-targeting agent, ZD6126: Assessment of toxicity and surrogate markers of vascular damage. Proc Am Soc Clin Oncol 21:110a, 2002 (abstr 439)
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
-
-
Radema, S.1
Beerepoot, L.V.2
Witteveen, P.O.3
-
71
-
-
0001410793
-
Clinical evaluation of ZD6474, an orally active inhibitor of VEGF signaling, in patients with solid tumors
-
abstr 325
-
Hurwitz H, Holden SN, Eckhardt SG, et al: Clinical evaluation of ZD6474, an orally active inhibitor of VEGF signaling, in patients with solid tumors. Proc Am Soc Clin Oncol 21:82a, 2002 (abstr 325)
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
-
-
Hurwitz, H.1
Holden, S.N.2
Eckhardt, S.G.3
-
72
-
-
0000397265
-
A randomized phase II trial comparing rhumab VEGF (recombinant humanized monoclonal antibody to vascular endothelial cell growth factor) plus carboplatin/paclitaxel (CP) to CP alone in patients with stage IIIB/IV NSCLC
-
abstr 1896
-
DeVore RF, Fehrenbacher L, Herbst RS, et al: A randomized phase II trial comparing rhumab VEGF (recombinant humanized monoclonal antibody to vascular endothelial cell growth factor) plus carboplatin/paclitaxel (CP) to CP alone in patients with stage IIIB/IV NSCLC. Proc Am Soc Clin Oncol 19:485a, 2000 (abstr 1896)
-
(2000)
Proc Am Soc Clin Oncol
, vol.19
-
-
DeVore, R.F.1
Fehrenbacher, L.2
Herbst, R.S.3
-
73
-
-
0003170893
-
A phase II trial of single-agent rhuMab VEGF (recombinant humanized monoclonal antibody to vascular endothelial cell growth factor) in patients with relapsed metastatic breast cancer
-
abstr 5c
-
Sledge G, Miller K, Novotny W, et al: A phase II trial of single-agent rhuMab VEGF (recombinant humanized monoclonal antibody to vascular endothelial cell growth factor) in patients with relapsed metastatic breast cancer. Proc Am Soc Clin Oncol 19:3a, 2000 (abstr 5c)
-
(2000)
Proc Am Soc Clin Oncol
, vol.19
-
-
Sledge, G.1
Miller, K.2
Novotny, W.3
-
74
-
-
0001674315
-
A randomized double-blind placebo-controlled trial of bevacizumab (anti-VEGF antibody) demonstrating a prolongation in time to progression in patients with metastatic renal cancer
-
abstr 15
-
Yang JC, Haworth L, Steinberg SM, et al: A randomized double-blind placebo-controlled trial of bevacizumab (anti-VEGF antibody) demonstrating a prolongation in time to progression in patients with metastatic renal cancer. Proc Am Soc Clin Oncol 21:5a, 2002 (abstr 15)
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
-
-
Yang, J.C.1
Haworth, L.2
Steinberg, S.M.3
-
75
-
-
0003037707
-
A randomized phase II trial comparing rhuMAb VEGF (recombinant humanized monoclonal antibody to vascular endothelial cell growth factor) plus 5-fluorouracil/leucovorin (FU/LV) to FU/LV alone in patients with metastatic colorectal cancer
-
abstr 939
-
Bergsland EK, Hurwitz H, Fehrenbacher L, et al: A randomized phase II trial comparing rhuMAb VEGF (recombinant humanized monoclonal antibody to vascular endothelial cell growth factor) plus 5-fluorouracil/leucovorin (FU/LV) to FU/LV alone in patients with metastatic colorectal cancer. Proc Am Soc Clin Oncol 19:242a, 2000 (abstr 939)
-
(2000)
Proc Am Soc Clin Oncol
, vol.19
-
-
Bergsland, E.K.1
Hurwitz, H.2
Fehrenbacher, L.3
-
76
-
-
0001496152
-
Bevacizumab (BV) + chemotherapy (CT) may improve survival in metastatic colorectal cancer (MCRC) subjects with unfavorable prognostic indicators
-
abstr 2247
-
Bergsland EK, Fehrenbacher L, Novotny W, et al: Bevacizumab (BV) + chemotherapy (CT) may improve survival in metastatic colorectal cancer (MCRC) subjects with unfavorable prognostic indicators. Proc Am Soc Clin Oncol 20:124b, 2001 (abstr 2247)
-
(2001)
Proc Am Soc Clin Oncol
, vol.20
-
-
Bergsland, E.K.1
Fehrenbacher, L.2
Novotny, W.3
-
77
-
-
0034727063
-
Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer
-
Saltz L, Cox J, Blanke C, et al: Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. N Engl J Med 343:905-914, 2000
-
(2000)
N Engl J Med
, vol.343
, pp. 905-914
-
-
Saltz, L.1
Cox, J.2
Blanke, C.3
-
78
-
-
0003305378
-
Successful long-term therapy with bevacizumab (Avastin) in solid tumors
-
abstr 32
-
Langmuir VK, Cobleigh MA, Herbst RS, et al: Successful long-term therapy with bevacizumab (Avastin) in solid tumors. Proc Am Soc Clin Oncol 21:9a, 2002 (abstr 32)
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
-
-
Langmuir, V.K.1
Cobleigh, M.A.2
Herbst, R.S.3
-
79
-
-
0013152742
-
Patterns of tumor progression during therapy with bevacizumab (BV) and chemotherapy (CT) for metastatic colorectal cancer (MCRC) and advanced non-small cell lung cancer (NSCLC)
-
abstr 1105
-
Kabbinavar FF, Johnson D, Langmuir VK: Patterns of tumor progression during therapy with bevacizumab (BV) and chemotherapy (CT) for metastatic colorectal cancer (MCRC) and advanced non-small cell lung cancer (NSCLC). Proc Am Soc Clin Oncol 20:227a, 2001 (abstr 1105)
-
(2001)
Proc Am Soc Clin Oncol
, vol.20
-
-
Kabbinavar, F.F.1
Johnson, D.2
Langmuir, V.K.3
-
80
-
-
0001410272
-
A phase I/II trial and pharmacokinetic (PK) study of SU5416 in combination with paclitaxel/carboplatin
-
abstr 389
-
Rosen PJ, Kabbinavar F, Figlin RA: A phase I/II trial and pharmacokinetic (PK) study of SU5416 in combination with paclitaxel/carboplatin. Proc Am Soc Clin Oncol 20:98a, 2001 (abstr 389)
-
(2001)
Proc Am Soc Clin Oncol
, vol.20
-
-
Rosen, P.J.1
Kabbinavar, F.2
Figlin, R.A.3
-
81
-
-
0030758682
-
Prevention of thrombotic disorders in cancer patients undergoing chemotherapy
-
Levine M: Prevention of thrombotic disorders in cancer patients undergoing chemotherapy. Thromb Haemost 78:133-136, 1997
-
(1997)
Thromb Haemost
, vol.78
, pp. 133-136
-
-
Levine, M.1
-
82
-
-
0002428162
-
Biological role of nitric oxide in platelet function
-
Moncada SHE, Berrazueta JR (eds). Madrid, Edicomplet
-
Radomski M, Moncada S: Biological role of nitric oxide in platelet function, in Moncada SHE, Berrazueta JR (eds): Clinical Relevance of Nitric Oxide in the Cardiovascular System. Madrid, Edicomplet, 1991, pp 45-56
-
(1991)
Clinical Relevance of Nitric Oxide in the Cardiovascular System
, pp. 45-56
-
-
Radomski, M.1
Moncada, S.2
-
83
-
-
0003236141
-
Activation of the coagulation cascade and endothelial cell perturbation during treatment with cisplatin, gemcitabine, and the angiogenesis inhibitor SU5416
-
abstr 21
-
Hoekman K, Kuenen B, Levi M, et al: Activation of the coagulation cascade and endothelial cell perturbation during treatment with cisplatin, gemcitabine, and the angiogenesis inhibitor SU5416. Proc Am Soc Clin Oncol 21:6a, 2002 (abstr 21)
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
-
-
Hoekman, K.1
Kuenen, B.2
Levi, M.3
-
84
-
-
0003264688
-
Incorporating angiogenesis inhibition with bevacizumab (anti-VEGF) into frontline chemotherapy with irinotecan (CPT-11), fluorouracil and leucovorin (FU/LV) for advanced colorectal cancer (advCRC): A toxicity analysis of ECOG study E2200
-
abstr 503
-
Giantonio BJ, Levy D, Catalano PJ, et al: Incorporating angiogenesis inhibition with bevacizumab (anti-VEGF) into frontline chemotherapy with irinotecan (CPT-11), fluorouracil and leucovorin (FU/LV) for advanced colorectal cancer (advCRC): A toxicity analysis of ECOG study E2200. Proc Am Soc Clin Oncol 21:126a, 2002 (abstr 503)
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
-
-
Giantonio, B.J.1
Levy, D.2
Catalano, P.J.3
|