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Volumn 44, Issue 1, 2005, Pages 340-351

The leucotriene C4 binding sites in multidrug resistance protein 1 (ABCC1) include the first membrane multiple spanning domain

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; CELLS; DRUG PRODUCTS; METABOLISM; TRANSPORT PROPERTIES; TUMORS;

EID: 11844276978     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi048853h     Document Type: Article
Times cited : (19)

References (61)
  • 1
    • 0018566696 scopus 로고
    • Purification of P-glycoprotein from plasma membrane vesicles of Chinese hamster ovary cell mutants with reduced colchicine permeability
    • Riordan, J. R., and Ling, V. (1979) Purification of P-glycoprotein from plasma membrane vesicles of Chinese hamster ovary cell mutants with reduced colchicine permeability, J. Biol. Chem. 254, 12701-12705.
    • (1979) J. Biol. Chem. , vol.254 , pp. 12701-12705
    • Riordan, J.R.1    Ling, V.2
  • 3
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman, M. M., and Pastan, I. (1993) Biochemistry of multidrug resistance mediated by the multidrug transporter, Annu. Rev. Biochem. 62, 385-427.
    • (1993) Annu. Rev. Biochem. , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 4
    • 0023278796 scopus 로고
    • Multidrug resistance in a human small cell lung cancer cell line selected in adriamycin
    • Mirski, S. E., Gerlach, J. H., and Cole, S. P. (1987) Multidrug resistance in a human small cell lung cancer cell line selected in adriamycin, Cancer Res. 47, 2594-2598.
    • (1987) Cancer Res. , vol.47 , pp. 2594-2598
    • Mirski, S.E.1    Gerlach, J.H.2    Cole, S.P.3
  • 5
    • 0025331434 scopus 로고
    • Patterns of cross-resistance in a multidrug-resistant small-cell lung carcinoma cell line
    • Cole, S. P. (1990) Patterns of cross-resistance in a multidrug-resistant small-cell lung carcinoma cell line, Cancer Chemother. Pharmacol. 26, 250-256.
    • (1990) Cancer Chemother. Pharmacol. , vol.26 , pp. 250-256
    • Cole, S.P.1
  • 7
    • 0030975889 scopus 로고    scopus 로고
    • Genetic dissection of the function of mammalian P-glycoproteins
    • Borst, P., and Schinkel, A. H. (1997) Genetic dissection of the function of mammalian P-glycoproteins, Trends Genet. 13, 217-222.
    • (1997) Trends Genet. , vol.13 , pp. 217-222
    • Borst, P.1    Schinkel, A.H.2
  • 8
    • 0029954843 scopus 로고    scopus 로고
    • P-glycoprotein-A mediator of multidrug resistance in tumour cells
    • Germann, U. A. (1996) P-glycoprotein-A mediator of multidrug resistance in tumour cells, Eur. J. Cancer 32A, 927-944.
    • (1996) Eur. J. Cancer , vol.32 A , pp. 927-944
    • Germann, U.A.1
  • 11
    • 0027960078 scopus 로고
    • Pharmacological characterization of multidrug resistance MRP-transfected human tumor cells
    • Cole, S. P. C., Sparks, K. E., Fraser, K., Loe, D. W., Grant, C. E., Wilson, G. M., and Deeley, R. G. (1994) Pharmacological characterization of multidrug resistance MRP-transfected human tumor cells, Cancer Res. 54, 5902-5910.
    • (1994) Cancer Res. , vol.54 , pp. 5902-5910
    • Cole, S.P.C.1    Sparks, K.E.2    Fraser, K.3    Loe, D.W.4    Grant, C.E.5    Wilson, G.M.6    Deeley, R.G.7
  • 13
    • 0030009305 scopus 로고    scopus 로고
    • Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport
    • Loe, D. W., Almquist, K. C., Deeley, R. G., and Cole, S. P. (1996) Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport, J. Biol. Chem. 271, 9675-9682.
    • (1996) J. Biol. Chem. , vol.271 , pp. 9675-9682
    • Loe, D.W.1    Almquist, K.C.2    Deeley, R.G.3    Cole, S.P.4
  • 14
    • 0030962253 scopus 로고    scopus 로고
    • ATP-dependent transport of aflatoxin B1 and its glutathione conjugates by the product of the multidrug resistance protein (MRP) gene
    • Loe, D. W., Stewart, R. K., Massey, T. E., Deeley, R. G., and Cole, S. P. (1997) ATP-dependent transport of aflatoxin B1 and its glutathione conjugates by the product of the multidrug resistance protein (MRP) gene, Mol. Pharmacol. 51, 1034-1041.
    • (1997) Mol. Pharmacol. , vol.51 , pp. 1034-1041
    • Loe, D.W.1    Stewart, R.K.2    Massey, T.E.3    Deeley, R.G.4    Cole, S.P.5
  • 15
    • 0033590513 scopus 로고    scopus 로고
    • Treatment of asthma with drugs modifying the leukotriene pathway
    • Drazen, J. M., Israel, E., and O'Byrne, P. M. (1999) Treatment of asthma with drugs modifying the leukotriene pathway, N. Engl. J. Med. 340, 197-206.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 197-206
    • Drazen, J.M.1    Israel, E.2    O'Byrne, P.M.3
  • 16
    • 0023177955 scopus 로고
    • Leukotrienes and lipoxins: Structures, biosynthesis, and biological effects
    • Samuelsson, B., Dahlen, S. E., Lindgren, J. A., Rouzer, C. A., and Serhan, C. N. (1987) Leukotrienes and lipoxins: structures, biosynthesis, and biological effects, Science 237, 1171-1176.
    • (1987) Science , vol.237 , pp. 1171-1176
    • Samuelsson, B.1    Dahlen, S.E.2    Lindgren, J.A.3    Rouzer, C.A.4    Serhan, C.N.5
  • 18
    • 0034703712 scopus 로고    scopus 로고
    • The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes
    • Robbiani, D. F., Finch, R. A., Jager, D., Muller, W. A., Sartorelli, A. C., and Randolph, G. J. (2000) The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes, Cell 103, 757-768.
    • (2000) Cell , vol.103 , pp. 757-768
    • Robbiani, D.F.1    Finch, R.A.2    Jager, D.3    Muller, W.A.4    Sartorelli, A.C.5    Randolph, G.J.6
  • 19
    • 0032211417 scopus 로고    scopus 로고
    • Multidrug resistance mediated by the ATP-binding cassette transporter protein MRP
    • Cole, S. P., and Deeley, R. G. (1998) Multidrug resistance mediated by the ATP-binding cassette transporter protein MRP, BioEssays 20, 931-940.
    • (1998) BioEssays , vol.20 , pp. 931-940
    • Cole, S.P.1    Deeley, R.G.2
  • 21
    • 0030863293 scopus 로고    scopus 로고
    • Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus
    • Hipfner, D. R., Almquist, K. C., Leslie, E. M., Gerlach, J. H., Grant, C. E., Deeley, R. G., and Cole, S. P. (1997) Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus, J. Biol. Chem. 272, 23623-23630.
    • (1997) J. Biol. Chem. , vol.272 , pp. 23623-23630
    • Hipfner, D.R.1    Almquist, K.C.2    Leslie, E.M.3    Gerlach, J.H.4    Grant, C.E.5    Deeley, R.G.6    Cole, S.P.7
  • 22
    • 0035853848 scopus 로고    scopus 로고
    • Major photoaffinity drug binding sites in multidrug resistance protein 1 (MRP1) are within transmembrane domains 10-11 and 16-17
    • Daoud, R., Julien, M., Gros, P., and Georges, E. (2001) Major photoaffinity drug binding sites in multidrug resistance protein 1 (MRP1) are within transmembrane domains 10-11 and 16-17, J. Biol. Chem. 276, 12324-12330.
    • (2001) J. Biol. Chem. , vol.276 , pp. 12324-12330
    • Daoud, R.1    Julien, M.2    Gros, P.3    Georges, E.4
  • 23
    • 0037465764 scopus 로고    scopus 로고
    • Binding of a photoaffinity analogue of glutathione to MRP1 (ABCC1) within two cytoplasmic regions (L0 and L1) as well as transmembrane domains 10-11 and 16-17
    • Karwatsky, J., Daoud, R., Cai, J., Gros, P., and Georges, E. (2003) Binding of a photoaffinity analogue of glutathione to MRP1 (ABCC1) within two cytoplasmic regions (L0 and L1) as well as transmembrane domains 10-11 and 16-17, Biochemistry 42, 3286-3294.
    • (2003) Biochemistry , vol.42 , pp. 3286-3294
    • Karwatsky, J.1    Daoud, R.2    Cai, J.3    Gros, P.4    Georges, E.5
  • 24
    • 0035851106 scopus 로고    scopus 로고
    • Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity
    • Ito, K., Oleschuk, C. J., Westlake, C., Vasa, M. Z., Deeley, R. G., and Cole, S. P. (2001) Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity, J. Biol. Chem. 276, 38108-38114.
    • (2001) J. Biol. Chem. , vol.276 , pp. 38108-38114
    • Ito, K.1    Oleschuk, C.J.2    Westlake, C.3    Vasa, M.Z.4    Deeley, R.G.5    Cole, S.P.6
  • 25
    • 0347683446 scopus 로고    scopus 로고
    • Molecular modeling correctly predicts the functional importance of Phe594 in transmembrane helix 11 of the multidrug resistance protein, MRP1 (ABCC1)
    • Campbell, J. D., Koike, K., Moreau, C., Sansom, M. S., Deeley, R. G., and Cole, S. P. (2004) Molecular modeling correctly predicts the functional importance of Phe594 in transmembrane helix 11 of the multidrug resistance protein, MRP1 (ABCC1), J. Biol. Chem. 279, 463-468.
    • (2004) J. Biol. Chem. , vol.279 , pp. 463-468
    • Campbell, J.D.1    Koike, K.2    Moreau, C.3    Sansom, M.S.4    Deeley, R.G.5    Cole, S.P.6
  • 26
    • 0037147341 scopus 로고    scopus 로고
    • Multiple membrane-associated tryptophan residues contribute to the transport activity and substrate specificity of the human multidrug resistance protein, MRP1
    • Koike, K., Oleschuk, C. J., Haimeur, A., Olsen, S. L., Deeley, R. G., and Cole, S. P. (2002) Multiple membrane-associated tryptophan residues contribute to the transport activity and substrate specificity of the human multidrug resistance protein, MRP1, J. Biol. Chem. 277, 49495-49503.
    • (2002) J. Biol. Chem. , vol.277 , pp. 49495-49503
    • Koike, K.1    Oleschuk, C.J.2    Haimeur, A.3    Olsen, S.L.4    Deeley, R.G.5    Cole, S.P.6
  • 27
    • 0037036427 scopus 로고    scopus 로고
    • Determinants of the substrate specificity of multidrug resistance protein 1: Role of amino acid residues with hydrogen bonding potential in predicted transmembrane helix 17
    • Zhang, D. W., Cole, S. P., and Deeley, R. G. (2002) Determinants of the substrate specificity of multidrug resistance protein 1: role of amino acid residues with hydrogen bonding potential in predicted transmembrane helix 17, J. Biol. Chem. 277, 20934-20941.
    • (2002) J. Biol. Chem. , vol.277 , pp. 20934-20941
    • Zhang, D.W.1    Cole, S.P.2    Deeley, R.G.3
  • 28
    • 0035860688 scopus 로고    scopus 로고
    • Identification of a nonconserved amino acid residue in multidrug resistance protein 1 important for determining substrate specificity: Evidence for functional interaction between transmembrane helices 14 and 17
    • Zhang, D. W., Cole, S. P., and Deeley, R. G. (2001) Identification of a nonconserved amino acid residue in multidrug resistance protein 1 important for determining substrate specificity: evidence for functional interaction between transmembrane helices 14 and 17, J. Biol. Chem. 276, 34966-34974.
    • (2001) J. Biol. Chem. , vol.276 , pp. 34966-34974
    • Zhang, D.W.1    Cole, S.P.2    Deeley, R.G.3
  • 29
    • 0037882044 scopus 로고    scopus 로고
    • Functional and structural consequences of cysteine substitutions in the NH2 proximal region of the human multidrug resistance protein 1 (MRP1/ABCC1)
    • Leslie, E. M., Letourneau, I. J., Deeley, R. G., and Cole, S. P. (2003) Functional and structural consequences of cysteine substitutions in the NH2 proximal region of the human multidrug resistance protein 1 (MRP1/ABCC1), Biochemistry 42, 5214-5224.
    • (2003) Biochemistry , vol.42 , pp. 5214-5224
    • Leslie, E.M.1    Letourneau, I.J.2    Deeley, R.G.3    Cole, S.P.4
  • 30
    • 0035844142 scopus 로고    scopus 로고
    • Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport
    • Ito, K., Olsen, S. L., Qiu, W., Deeley, R. G., and Cole, S. P. (2001) Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport, J. Biol. Chem. 276, 15616-15624.
    • (2001) J. Biol. Chem. , vol.276 , pp. 15616-15624
    • Ito, K.1    Olsen, S.L.2    Qiu, W.3    Deeley, R.G.4    Cole, S.P.5
  • 31
    • 0036828695 scopus 로고    scopus 로고
    • Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity
    • Haimeur, A., Deeley, R. G., and Cole, S. P. (2002) Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity, J. Biol. Chem. 277, 41326-41333.
    • (2002) J. Biol. Chem. , vol.277 , pp. 41326-41333
    • Haimeur, A.1    Deeley, R.G.2    Cole, S.P.3
  • 32
    • 0037113970 scopus 로고    scopus 로고
    • Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1
    • Yang, Y., Chen, Q., and Zhang, J. T. (2002) Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1, J. Biol. Chem. 277, 44268-44277.
    • (2002) J. Biol. Chem. , vol.277 , pp. 44268-44277
    • Yang, Y.1    Chen, Q.2    Zhang, J.T.3
  • 33
    • 0027984511 scopus 로고
    • The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates
    • Leier, I., Jedlitschky, G., Buchholz, U., Cole, S. P., Deeley, R. G., and Keppler, D. (1994) The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates, J. Biol. Chem. 269, 27807-27810.
    • (1994) J. Biol. Chem. , vol.269 , pp. 27807-27810
    • Leier, I.1    Jedlitschky, G.2    Buchholz, U.3    Cole, S.P.4    Deeley, R.G.5    Keppler, D.6
  • 34
    • 0028347079 scopus 로고
    • Characterization of the ATP-dependent leukotriene C4 export carrier in mastocytoma cells
    • Leier, I., Jedlitschky, G., Buchholz, U., and Keppler, D. (1994) Characterization of the ATP-dependent leukotriene C4 export carrier in mastocytoma cells, Eur. J. Biochem. 220, 599-606.
    • (1994) Eur. J. Biochem. , vol.220 , pp. 599-606
    • Leier, I.1    Jedlitschky, G.2    Buchholz, U.3    Keppler, D.4
  • 35
    • 0029918142 scopus 로고    scopus 로고
    • ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids
    • Loe, D. W., Almquist, K. C., Cole, S. P., and Deeley, R. G. (1996) ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids, J. Biol. Chem. 271, 9683-9689.
    • (1996) J. Biol. Chem. , vol.271 , pp. 9683-9689
    • Loe, D.W.1    Almquist, K.C.2    Cole, S.P.3    Deeley, R.G.4
  • 36
    • 0035914401 scopus 로고    scopus 로고
    • Characterization of binding of leukotriene C4 by human multidrug resistance protein 1: Evidence of differential interactions with NH2- and COOH-proximal halves of the protein
    • Qian, Y. M., Qiu, W., Gao, M., Westlake, C. J., Cole, S. P., and Deeley, R. G. (2001) Characterization of binding of leukotriene C4 by human multidrug resistance protein 1: evidence of differential interactions with NH2- and COOH-proximal halves of the protein, J. Biol. Chem. 276, 38636-38644.
    • (2001) J. Biol. Chem. , vol.276 , pp. 38636-38644
    • Qian, Y.M.1    Qiu, W.2    Gao, M.3    Westlake, C.J.4    Cole, S.P.5    Deeley, R.G.6
  • 37
    • 0030685129 scopus 로고    scopus 로고
    • Topology mapping of the amino-terminal half of multidrug resistance-associated protein by epitope insertion and immunofluorescence
    • Kast, C., and Gros, P. (1997) Topology mapping of the amino-terminal half of multidrug resistance-associated protein by epitope insertion and immunofluorescence, J. Biol. Chem. 272, 26479-26487.
    • (1997) J. Biol. Chem. , vol.272 , pp. 26479-26487
    • Kast, C.1    Gros, P.2
  • 38
    • 0032562137 scopus 로고    scopus 로고
    • Epitope insertion favors a six transmembrane domain model for the carboxy-terminal portion of the multidrug resistance-associated protein
    • Kast, C., and Gros, P. (1998) Epitope insertion favors a six transmembrane domain model for the carboxy-terminal portion of the multidrug resistance-associated protein, Biochemistry 37, 2305-2313.
    • (1998) Biochemistry , vol.37 , pp. 2305-2313
    • Kast, C.1    Gros, P.2
  • 40
    • 0028284288 scopus 로고
    • Characterization of rhodamine 123 binding to P-glycoprotein in human multidrug-resistant cells
    • Nare, B., Prichard, R. K., and Georges, E. (1994) Characterization of rhodamine 123 binding to P-glycoprotein in human multidrug-resistant cells, Mol. Pharmacol. 45, 1145-1152.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 1145-1152
    • Nare, B.1    Prichard, R.K.2    Georges, E.3
  • 41
    • 0025940471 scopus 로고
    • Modulation of ATP and drug binding by monoclonal antibodies against P-glycoprotein
    • Georges, E., Zhang, J. T., and Ling, V. (1991) Modulation of ATP and drug binding by monoclonal antibodies against P-glycoprotein, J. Cell Physiol. 148, 479-484.
    • (1991) J. Cell Physiol. , vol.148 , pp. 479-484
    • Georges, E.1    Zhang, J.T.2    Ling, V.3
  • 42
    • 0015236352 scopus 로고
    • Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane
    • Fairbanks, G., Steck, T. L., and Wallach, D. F. (1971) Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane, Biochemistry 10, 2606-2617.
    • (1971) Biochemistry , vol.10 , pp. 2606-2617
    • Fairbanks, G.1    Steck, T.L.2    Wallach, D.F.3
  • 44
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin, H., Staehelin, T., and Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications, Proc. Natl. Acad. Sci. U.S.A. 76, 4350-4354.
    • (1979) Proc. Natl. Acad. Sci. U.S.A. , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 45
    • 0029912351 scopus 로고    scopus 로고
    • ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump
    • Leier, I., Jedlitschky, G., Buchholz, U., Center, M., Cole, S. P., Deeley, R. G., and Keppler, D. (1996) ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump, Biochem. J. 314 (Part 2), 433-437.
    • (1996) Biochem. J. , vol.314 , Issue.2 PART , pp. 433-437
    • Leier, I.1    Jedlitschky, G.2    Buchholz, U.3    Center, M.4    Cole, S.P.5    Deeley, R.G.6    Keppler, D.7
  • 46
    • 0028001416 scopus 로고
    • ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein
    • Jedlitschky, G., Leier, I., Buchholz, U., Center, M., and Keppler, D. (1994) ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein, Cancer Res. 54, 4833-4836.
    • (1994) Cancer Res. , vol.54 , pp. 4833-4836
    • Jedlitschky, G.1    Leier, I.2    Buchholz, U.3    Center, M.4    Keppler, D.5
  • 47
    • 0032534064 scopus 로고    scopus 로고
    • Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): Evidence for cotransport with reduced glutathione
    • Loe, D. W., Deeley, R. G., and Cole, S. P. (1998) Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): evidence for cotransport with reduced glutathione, Cancer Res. 58, 5130-5136.
    • (1998) Cancer Res. , vol.58 , pp. 5130-5136
    • Loe, D.W.1    Deeley, R.G.2    Cole, S.P.3
  • 48
    • 0030678131 scopus 로고    scopus 로고
    • Evidence that the multidrug resistance protein (MRP) functions as a co-transporter of glutathione and natural product toxins
    • Rappa, G., Lorico, A., Flavell, R. A., and Sartorelli, A. C. (1997) Evidence that the multidrug resistance protein (MRP) functions as a co-transporter of glutathione and natural product toxins, Cancer Res. 57, 5232-5237.
    • (1997) Cancer Res. , vol.57 , pp. 5232-5237
    • Rappa, G.1    Lorico, A.2    Flavell, R.A.3    Sartorelli, A.C.4
  • 49
    • 0028986245 scopus 로고
    • The leukotriene LTD4 receptor antagonist MK571 specifically modulates MRP associated multidrug resistance
    • Gekeler, V., Ise, W., Sanders, K. H., Ulrich, W. R., and Beck, J. (1995) The leukotriene LTD4 receptor antagonist MK571 specifically modulates MRP associated multidrug resistance, Biochem. Biophys. Res. Commun. 208, 345-352.
    • (1995) Biochem. Biophys. Res. Commun. , vol.208 , pp. 345-352
    • Gekeler, V.1    Ise, W.2    Sanders, K.H.3    Ulrich, W.R.4    Beck, J.5
  • 50
    • 0030063480 scopus 로고    scopus 로고
    • Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump
    • Jedlitschky, G., Leier, I., Buchholz, U., Barnouin, K., Kurz, G., and Keppler, D. (1996) Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump, Cancer Res. 56, 988-994.
    • (1996) Cancer Res. , vol.56 , pp. 988-994
    • Jedlitschky, G.1    Leier, I.2    Buchholz, U.3    Barnouin, K.4    Kurz, G.5    Keppler, D.6
  • 51
    • 0031756730 scopus 로고    scopus 로고
    • Epitope mapping of monoclonal antibodies specific for the 190-kDa multidrug resistance protein (MRP)
    • Hipfner, D. R., Gao, M., Scheffer, G., Scheper, R. J., Deeley, R. G., and Cole, S. P. (1998) Epitope mapping of monoclonal antibodies specific for the 190-kDa multidrug resistance protein (MRP), Br. J. Cancer 78, 1134-1140.
    • (1998) Br. J. Cancer , vol.78 , pp. 1134-1140
    • Hipfner, D.R.1    Gao, M.2    Scheffer, G.3    Scheper, R.J.4    Deeley, R.G.5    Cole, S.P.6
  • 52
    • 0029987631 scopus 로고    scopus 로고
    • Location of a protease-hypersensitive region in the multidrug resistance protein (MRP) by mapping of the epitope of MRP-specific monoclonal antibody QCRL-1
    • Hipfner, D. R., Almquist, K. C., Stride, B. D., Deeley, R. G., and Cole, S. P. (1996) Location of a protease-hypersensitive region in the multidrug resistance protein (MRP) by mapping of the epitope of MRP-specific monoclonal antibody QCRL-1, Cancer Res. 56, 3307-3314.
    • (1996) Cancer Res. , vol.56 , pp. 3307-3314
    • Hipfner, D.R.1    Almquist, K.C.2    Stride, B.D.3    Deeley, R.G.4    Cole, S.P.5
  • 54
    • 0032508365 scopus 로고    scopus 로고
    • Identification of the domains of photoincorporation of the 3′- and 7-benzophenone analogues of taxol in the carboxyl-terminal half of murine mdr1b P-glycoprotein
    • Wu, Q., Bounaud, P. Y., Kuduk, S. D., Yang, C. P., Ojima, I., Horwitz, S. B., and Orr, G. A. (1998) Identification of the domains of photoincorporation of the 3′- and 7-benzophenone analogues of taxol in the carboxyl-terminal half of murine mdr1b P-glycoprotein, Biochemistry 37, 11272-11279.
    • (1998) Biochemistry , vol.37 , pp. 11272-11279
    • Wu, Q.1    Bounaud, P.Y.2    Kuduk, S.D.3    Yang, C.P.4    Ojima, I.5    Horwitz, S.B.6    Orr, G.A.7
  • 55
    • 0029896988 scopus 로고    scopus 로고
    • Mutational analysis of the predicted first transmembrane segment of each homologous half of human P-glycoprotein suggests that they are symmetrically arranged in the membrane
    • Loo, T. W., and Clarke, D. M. (1996) Mutational analysis of the predicted first transmembrane segment of each homologous half of human P-glycoprotein suggests that they are symmetrically arranged in the membrane, J. Biol. Chem. 271, 15414-15419.
    • (1996) J. Biol. Chem. , vol.271 , pp. 15414-15419
    • Loo, T.W.1    Clarke, D.M.2
  • 56
    • 0027512768 scopus 로고
    • Functional consequences of proline mutations in the predicted transmembrane domain of P-glycoprotein
    • Loo, T. W., and Clarke, D. M. (1993) Functional consequences of proline mutations in the predicted transmembrane domain of P-glycoprotein, J. Biol. Chem. 268, 3143-3149.
    • (1993) J. Biol. Chem. , vol.268 , pp. 3143-3149
    • Loo, T.W.1    Clarke, D.M.2
  • 57
    • 0344629891 scopus 로고    scopus 로고
    • Identification of the structural and functional boundaries of the multidrug resistance protein 1 cytoplasmic loop 3
    • Westlake, C. J., Qian, Y. M., Gao, M., Vasa, M., Cole, S. P., and Deeley, R. G. (2003) Identification of the structural and functional boundaries of the multidrug resistance protein 1 cytoplasmic loop 3, Biochemistry 42, 14099-14113.
    • (2003) Biochemistry , vol.42 , pp. 14099-14113
    • Westlake, C.J.1    Qian, Y.M.2    Gao, M.3    Vasa, M.4    Cole, S.P.5    Deeley, R.G.6
  • 58
    • 0037927606 scopus 로고    scopus 로고
    • Identification of domains participating in the substrate specificity and subcellular localization of the multidrug resistance proteins MRP1 and MRP2
    • Konno, T., Ebihara, T., Hisaeda, K., Uchiumi, T., Nakamura, T., Shirakusa, T., Kuwano, M., and Wada, M. (2003) Identification of domains participating in the substrate specificity and subcellular localization of the multidrug resistance proteins MRP1 and MRP2, J. Biol. Chem. 278, 22908-22917.
    • (2003) J. Biol. Chem. , vol.278 , pp. 22908-22917
    • Konno, T.1    Ebihara, T.2    Hisaeda, K.3    Uchiumi, T.4    Nakamura, T.5    Shirakusa, T.6    Kuwano, M.7    Wada, M.8
  • 60
    • 0035823075 scopus 로고    scopus 로고
    • Structure of MsbA from E. coli: A homolog of the multidrug resistance ATP binding cassette (ABC) transporters
    • Chang, G., and Roth, C. B. (2001) Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters, Science 293, 1793-1800.
    • (2001) Science , vol.293 , pp. 1793-1800
    • Chang, G.1    Roth, C.B.2
  • 61
    • 0038799725 scopus 로고    scopus 로고
    • Structure of MsbA from Vibrio cholera: A multidrug resistance ABC transporter homolog in a closed conformation
    • Chang, G. (2003) Structure of MsbA from Vibrio cholera: a multidrug resistance ABC transporter homolog in a closed conformation, J. Mol. Biol. 330, 419-430.
    • (2003) J. Mol. Biol. , vol.330 , pp. 419-430
    • Chang, G.1


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