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Volumn 340, Issue 3, 1999, Pages 197-206

Treatment of asthma with drugs modifying the leukotriene pathway

Author keywords

[No Author keywords available]

Indexed keywords

2 CYCLOPENTYL 2 [4 (2 QUINOLINYLMETHOXY)PHENYL]ACETIC ACID; 3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 (2 QUINOLINYLMETHOXY) 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; 3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; ACETYLSALICYLIC ACID; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CINALUKAST; GLUCOCORTICOID; LEUKOTRIENE RECEPTOR; LEUKOTRIENE RECEPTOR BLOCKING AGENT; LIPOXYGENASE; LIPOXYGENASE INHIBITOR; MONTELUKAST; POBILUKAST; PRANLUKAST; THEOPHYLLINE; UNCLASSIFIED DRUG; VERLUKAST; ZAFIRLUKAST; ZILEUTON;

EID: 0033590513     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM199901213400306     Document Type: Review
Times cited : (781)

References (110)
  • 1
    • 0001465756 scopus 로고
    • Leukotriene c: A slow-reacting substance from murine mastocytoma cells
    • Murphy RC, Hammarstrom S, Samuelsson B. Leukotriene C: a slow-reacting substance from murine mastocytoma cells. Proc Natl Acad Sci USA 1979;76:4275-9.
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 4275-4279
    • Murphy, R.C.1    Hammarstrom, S.2    Samuelsson, B.3
  • 2
    • 84980124399 scopus 로고
    • Liberation of slow-reacting smooth muscle-stimulating substance in anaphylaxis
    • Kellaway CH, Trethewie ER. Liberation of slow-reacting smooth muscle-stimulating substance in anaphylaxis. Q J Exp Physiol 1940;30:121-45.
    • (1940) Q J Exp Physiol , vol.30 , pp. 121-145
    • Kellaway, C.H.1    Trethewie, E.R.2
  • 3
    • 0000951027 scopus 로고
    • Comparative airway and vascular activities of leukotrienes C-1 and D in vivo and in vitro
    • Drazen JM, Austen KF, Lewis RA, et al. Comparative airway and vascular activities of leukotrienes C-1 and D in vivo and in vitro. Proc Natl Acad Sci U S A 1980;77:4354-8.
    • (1980) Proc Natl Acad Sci U S A , vol.77 , pp. 4354-4358
    • Drazen, J.M.1    Austen, K.F.2    Lewis, R.A.3
  • 4
    • 0018381379 scopus 로고
    • Differential effects of a partially purified preparation of slow-reacting substance of anaphylaxis on guinea pig tracheal spirals and parenchymal strips
    • Drazen JM, Lewis RA, Wasserman SI, Orange RP, Austen KF. Differential effects of a partially purified preparation of slow-reacting substance of anaphylaxis on guinea pig tracheal spirals and parenchymal strips. J Clin Invest 1979;63:1-5.
    • (1979) J Clin Invest , vol.63 , pp. 1-5
    • Drazen, J.M.1    Lewis, R.A.2    Wasserman, S.I.3    Orange, R.P.4    Austen, K.F.5
  • 6
    • 0019966111 scopus 로고
    • Bronchoconstrictor effects of leukotriene C in humans
    • Weiss JW, Drazen JM, Coles N, et al. Bronchoconstrictor effects of leukotriene C in humans. Science 1982;216:196-8.
    • (1982) Science , vol.216 , pp. 196-198
    • Weiss, J.W.1    Drazen, J.M.2    Coles, N.3
  • 7
    • 0020691486 scopus 로고
    • Effects of leukotriene D on the airways in asthma
    • Griffin M, Weiss JW, Leitch AG, et al. Effects of leukotriene D on the airways in asthma. N Engl J Med 1983;308:436-9.
    • (1983) N Engl J Med , vol.308 , pp. 436-439
    • Griffin, M.1    Weiss, J.W.2    Leitch, A.G.3
  • 10
    • 0025810972 scopus 로고
    • Attenuation of inhaled allergen-induced airway microvascular leakage and airflow obstruction in guinea pigs by a 5-lipoxygenase inhibitor (A-63162)
    • Hui KP, Lotvall J, Chung KF, Barnes PJ. Attenuation of inhaled allergen-induced airway microvascular leakage and airflow obstruction in guinea pigs by a 5-lipoxygenase inhibitor (A-63162). Am Rev Respir Dis 1991; 143:1015-9.
    • (1991) Am Rev Respir Dis , vol.143 , pp. 1015-1019
    • Hui, K.P.1    Lotvall, J.2    Chung, K.F.3    Barnes, P.J.4
  • 13
    • 0028916313 scopus 로고
    • Blockade of eosinophil migration by 5-lipoxygenase and cyclooxygenase inhibition in explanted guinea pig trachealis
    • Munoz NM, Leff AR. Blockade of eosinophil migration by 5-lipoxygenase and cyclooxygenase inhibition in explanted guinea pig trachealis. Am J Physiol 1995;268:L446-L454.
    • (1995) Am J Physiol , vol.268
    • Munoz, N.M.1    Leff, A.R.2
  • 14
    • 0020642779 scopus 로고
    • Effects of leukotrienes C4 and D4 on glycoprotein and lysozyme secretion by human bronchial mucosa
    • Coles SJ, Neill KH, Reid LM, et al. Effects of leukotrienes C4 and D4 on glycoprotein and lysozyme secretion by human bronchial mucosa. Prostaglandins 1983;25:155-70.
    • (1983) Prostaglandins , vol.25 , pp. 155-170
    • Coles, S.J.1    Neill, K.H.2    Reid, L.M.3
  • 15
    • 0025810991 scopus 로고
    • The potential roles of leukotrienes in bronchial asthma
    • Piacentini GL, Kaliner MA. The potential roles of leukotrienes in bronchial asthma. Am Rev Respir Dis 1991;143:S96-S99.
    • (1991) Am Rev Respir Dis , vol.143
    • Piacentini, G.L.1    Kaliner, M.A.2
  • 16
    • 0027853957 scopus 로고
    • Lipoxygenase products regulate proliferation of granulocyte-macrophage progenitors
    • Pasquale D, Chikkappa G. Lipoxygenase products regulate proliferation of granulocyte-macrophage progenitors. Exp Hematol 1993;21:1361-5.
    • (1993) Exp Hematol , vol.21 , pp. 1361-1365
    • Pasquale, D.1    Chikkappa, G.2
  • 17
    • 0029659031 scopus 로고    scopus 로고
    • 4 induced vascular smooth muscle cell proliferation: A possible role in myointimal hyperplasia
    • 4 induced vascular smooth muscle cell proliferation: a possible role in myointimal hyperplasia. Thromb Haemost 1996;76:99-104.
    • (1996) Thromb Haemost , vol.76 , pp. 99-104
    • Porreca, E.1    Di Febbo, C.2    Di Sciullo, A.3
  • 19
    • 0030659604 scopus 로고    scopus 로고
    • Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains
    • Markel P, Shu P, Ebeling C, et al. Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains. Nat Genet 1997;17: 280-4.
    • (1997) Nat Genet , vol.17 , pp. 280-284
    • Markel, P.1    Shu, P.2    Ebeling, C.3
  • 20
    • 0020597565 scopus 로고
    • Leukotrienes: Mediators of immediate hypersensitivity reactions and inflammation
    • Samuelsson B. Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. Science 1983;220:568-75.
    • (1983) Science , vol.220 , pp. 568-575
    • Samuelsson, B.1
  • 21
    • 0025164256 scopus 로고
    • Leukotrienes and other products of the 5-lipoxygenase pathway: Biochemistry and relation to pathobiology in human diseases
    • Lewis RA, Austen KF, Soberman RJ. Leukotrienes and other products of the 5-lipoxygenase pathway: biochemistry and relation to pathobiology in human diseases. N Engl J Med 1990;323:645-55.
    • (1990) N Engl J Med , vol.323 , pp. 645-655
    • Lewis, R.A.1    Austen, K.F.2    Soberman, R.J.3
  • 22
    • 0028566488 scopus 로고
    • The role of leukotrienes in inflammation
    • Henderson WR Jr. The role of leukotrienes in inflammation. Ann Intern Med 1994;121:684-97.
    • (1994) Ann Intern Med , vol.121 , pp. 684-697
    • Henderson W.R., Jr.1
  • 23
    • 0025869402 scopus 로고
    • Role of phospholipase in generating lipid second messengers in signal transduction
    • Dennis EA, Rhee SG, Billah MM, Hannun YA. Role of phospholipase in generating lipid second messengers in signal transduction. FASEB J 1991;5:2068-77
    • (1991) FASEB J , vol.5 , pp. 2068-2077
    • Dennis, E.A.1    Rhee, S.G.2    Billah, M.M.3    Hannun, Y.A.4
  • 25
    • 0025022489 scopus 로고
    • Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis
    • Dixon RA, Diehl RE, Opas E, et al. Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis. Nature 1990;343:282-4.
    • (1990) Nature , vol.343 , pp. 282-284
    • Dixon, R.A.1    Diehl, R.E.2    Opas, E.3
  • 26
    • 0028486965 scopus 로고
    • Increases in 5-lipoxygenase activating protein expression account for enhanced capacity for 5-lipoxygenase metabolism that accompanies differentiation of peripheral blood monocytes into alveolar macrophages
    • Coffey MJ, Wilcoxen SE, Peters-Golden M. Increases in 5-lipoxygenase activating protein expression account for enhanced capacity for 5-lipoxygenase metabolism that accompanies differentiation of peripheral blood monocytes into alveolar macrophages. Am J Respir Cell Mol Biol 1994;11:153-8.
    • (1994) Am J Respir Cell Mol Biol , vol.11 , pp. 153-158
    • Coffey, M.J.1    Wilcoxen, S.E.2    Peters-Golden, M.3
  • 27
    • 0026332275 scopus 로고
    • Pharmacokinetics, safety, and ability to diminish leukotriene synthesis by zileuton, an inhibitor of 5-lipoxygenase
    • Rubin P, Dube L, Braeckman R, et al. Pharmacokinetics, safety, and ability to diminish leukotriene synthesis by zileuton, an inhibitor of 5-lipoxygenase. Agents Actions Suppl 1991;35:103-16.
    • (1991) Agents Actions Suppl , vol.35 , pp. 103-116
    • Rubin, P.1    Dube, L.2    Braeckman, R.3
  • 30
    • 0024392871 scopus 로고
    • The identification of a distinct export step following the biosynthesis of leukotriene C4 by human eosinophils
    • Lim BK, Owen WF Jr, Austen KF, Soberman RJ. The identification of a distinct export step following the biosynthesis of leukotriene C4 by human eosinophils. J Biol Chem 1989;264:12885-9.
    • (1989) J Biol Chem , vol.264 , pp. 12885-12889
    • Lim, B.K.1    Owen W.F., Jr.2    Austen, K.F.3    Soberman, R.J.4
  • 31
    • 0030009305 scopus 로고    scopus 로고
    • 4 and chemotherapeutic agents in membrane vesicles: Demonstration of glutathione-dependent vincristine transport
    • 4 and chemotherapeutic agents in membrane vesicles: demonstration of glutathione-dependent vincristine transport. J Biol Chem 1996;271:9675-82.
    • (1996) J Biol Chem , vol.271 , pp. 9675-9682
    • Loe, D.W.1    Almquist, K.C.2    Deeley, R.G.3    Cole, S.P.C.4
  • 32
    • 0025572770 scopus 로고
    • Leukotriene E4 elimination and metabolism in normal human subjects
    • Sala A, Voelkel N, Maclouf J, Murphy RC. Leukotriene E4 elimination and metabolism in normal human subjects. J Biol Chem 1990;265:21771-8.
    • (1990) J Biol Chem , vol.265 , pp. 21771-21778
    • Sala, A.1    Voelkel, N.2    Maclouf, J.3    Murphy, R.C.4
  • 33
    • 0026722088 scopus 로고
    • Entry rate and metabolism of leukotriene C4 into vascular compartment in healthy subjects
    • Maclouf J, Antoine C, De Caterina R, et al. Entry rate and metabolism of leukotriene C4 into vascular compartment in healthy subjects. Am J Physiol 1992;263:H244-H249.
    • (1992) Am J Physiol , vol.263
    • Maclouf, J.1    Antoine, C.2    De Caterina, R.3
  • 34
    • 0005224855 scopus 로고    scopus 로고
    • Pathways of leukotriene metabolism in isolated cell models and human subjects
    • Drazen JM, Dahlen SE, Lee T, eds. New York: Academic Press
    • Murphy RC, Wheelan P. Pathways of leukotriene metabolism in isolated cell models and human subjects. In: Drazen JM, Dahlen SE, Lee T, eds. 5-Lipoxygenase products in asthma. New York: Academic Press, 1998:87-123.
    • (1998) 5-Lipoxygenase Products in Asthma , pp. 87-123
    • Murphy, R.C.1    Wheelan, P.2
  • 35
    • 0026602394 scopus 로고
    • Leukotriene A4 hydrolase: An anion activated peptidase
    • Wetterholm A, Haeggstrom JZ. Leukotriene A4 hydrolase: an anion activated peptidase. Biochim Biophys Acta 1992;1123:275-81.
    • (1992) Biochim Biophys Acta , vol.1123 , pp. 275-281
    • Wetterholm, A.1    Haeggstrom, J.Z.2
  • 36
    • 0023618035 scopus 로고
    • Molecular cloning of a cDNA coding for human leukotriene A4 hydrolase: Complete primary structure of an enzyme involved in eicosanoid synthesis
    • Minami M, Ohno S, Kawasaki H, et al. Molecular cloning of a cDNA coding for human leukotriene A4 hydrolase: complete primary structure of an enzyme involved in eicosanoid synthesis. J Biol Chem 1987;262:13873-6.
    • (1987) J Biol Chem , vol.262 , pp. 13873-13876
    • Minami, M.1    Ohno, S.2    Kawasaki, H.3
  • 37
    • 0031282523 scopus 로고    scopus 로고
    • Protein expression, characterization, and regulation of CYP4F4 and CYP4F5 cloned from rat brain
    • Kawashima H, Kusunose E, Thompson CM, Strobel HW. Protein expression, characterization, and regulation of CYP4F4 and CYP4F5 cloned from rat brain. Arch Biochem Biophys 1997;347:148-54.
    • (1997) Arch Biochem Biophys , vol.347 , pp. 148-154
    • Kawashima, H.1    Kusunose, E.2    Thompson, C.M.3    Strobel, H.W.4
  • 38
    • 0030068919 scopus 로고    scopus 로고
    • cDNA cloning, expression, and mucagenesis study of leukotriene B4 12-hydroxydehydrogenase
    • Yokomizo T, Ogawa Y, Uozumi N, Kume K, Izumi T, Shimizu T. cDNA cloning, expression, and mucagenesis study of leukotriene B4 12-hydroxydehydrogenase. J Biol Chem 1996;271:2844-50.
    • (1996) J Biol Chem , vol.271 , pp. 2844-2850
    • Yokomizo, T.1    Ogawa, Y.2    Uozumi, N.3    Kume, K.4    Izumi, T.5    Shimizu, T.6
  • 39
    • 0029181674 scopus 로고
    • Prostanoid and leukotriene receptors: A progress report from the IUPHAR working parties on classification and nomenclature
    • Coleman RA, Eglen RM, Jones RL, et al. Prostanoid and leukotriene receptors: a progress report from the IUPHAR working parties on classification and nomenclature. Adv Prostaglandin Thromboxane Leukot Res 1995;23:283-5.
    • (1995) Adv Prostaglandin Thromboxane Leukot Res , vol.23 , pp. 283-285
    • Coleman, R.A.1    Eglen, R.M.2    Jones, R.L.3
  • 40
    • 0030976460 scopus 로고    scopus 로고
    • A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis
    • Yokomizo T, Izumi T, Chang K, Takuwa Y, Shimizu T. A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis, Nature 1997;387:620-4.
    • (1997) Nature , vol.387 , pp. 620-624
    • Yokomizo, T.1    Izumi, T.2    Chang, K.3    Takuwa, Y.4    Shimizu, T.5
  • 41
    • 0020611487 scopus 로고
    • Pharmacology of leukotrienes
    • Piper PJ. Pharmacology of leukotrienes. Br Med Bull 1983;39:255-9.
    • (1983) Br Med Bull , vol.39 , pp. 255-259
    • Piper, P.J.1
  • 42
    • 0029823459 scopus 로고    scopus 로고
    • Lipid mediator networks in cell signaling: Update and impact of cytokines
    • Serhan CN, Haeggstrom JZ, Leslie CC. Lipid mediator networks in cell signaling: update and impact of cytokines. FASEB J 1996;10:1147-58.
    • (1996) FASEB J , vol.10 , pp. 1147-1158
    • Serhan, C.N.1    Haeggstrom, J.Z.2    Leslie, C.C.3
  • 43
    • 0019308374 scopus 로고
    • Slow reacting substances of anaphylaxis: Identification of leukotrienes C-1 and D from human and rat sources
    • Lewis RA, Austen KF, Drazen JM, Clark DA, Marfat A, Corey EJ. Slow reacting substances of anaphylaxis: identification of leukotrienes C-1 and D from human and rat sources. Proc Natl Acad Sci U S A 1980;77: 3710-4.
    • (1980) Proc Natl Acad Sci U S A , vol.77 , pp. 3710-3714
    • Lewis, R.A.1    Austen, K.F.2    Drazen, J.M.3    Clark, D.A.4    Marfat, A.5    Corey, E.J.6
  • 44
    • 0019131897 scopus 로고
    • Identification of the C(6)-S-conjugate of leukotriene A with cysteine as a naturally occurring slow reacting substance of anaphylaxis (SRS-A): Importance of the 11-cis-geometry for biological activity
    • Lewis RA, Drazen JM, Austen KF, Clark DA, Corey EJ. Identification of the C(6)-S-conjugate of leukotriene A with cysteine as a naturally occurring slow reacting substance of anaphylaxis (SRS-A): importance of the 11-cis-geometry for biological activity. Biochem Biophys Res Commun 1980;96:271-7.
    • (1980) Biochem Biophys Res Commun , vol.96 , pp. 271-277
    • Lewis, R.A.1    Drazen, J.M.2    Austen, K.F.3    Clark, D.A.4    Corey, E.J.5
  • 45
    • 0023521610 scopus 로고
    • Pharmacologic profile of SK&F 104353: A novel, potent and selective peptidoleukotriene receptor antagonist in guinea pig and human airways
    • Hay DW, Muccitelli RM, Tucker SS, et al. Pharmacologic profile of SK&F 104353: a novel, potent and selective peptidoleukotriene receptor antagonist in guinea pig and human airways. J Pharmacol Exp Ther 1987; 243:474-81.
    • (1987) J Pharmacol Exp Ther , vol.243 , pp. 474-481
    • Hay, D.W.1    Muccitelli, R.M.2    Tucker, S.S.3
  • 46
    • 0022592154 scopus 로고
    • Pharmacological evidence that human intralobar airways do not contain different receptors that mediate contractions to leukotriene C4 and leukotriene D4
    • Buckner CK, Krell RD, Laravuso RB, Coursin DB, Bernstein PR, Will JA. Pharmacological evidence that human intralobar airways do not contain different receptors that mediate contractions to leukotriene C4 and leukotriene D4. J Pharmacol Exp Ther 1986;237:558-62.
    • (1986) J Pharmacol Exp Ther , vol.237 , pp. 558-562
    • Buckner, C.K.1    Krell, R.D.2    Laravuso, R.B.3    Coursin, D.B.4    Bernstein, P.R.5    Will, J.A.6
  • 47
    • 0019997849 scopus 로고
    • Pharmacological study of the contractile activity of leukotriene C4 and D4 on isolated human airway smooth muscle
    • Jones TR, Davis C, Daniel EE. Pharmacological study of the contractile activity of leukotriene C4 and D4 on isolated human airway smooth muscle. Can J Physiol Pharmacol 1982;60:638-43.
    • (1982) Can J Physiol Pharmacol , vol.60 , pp. 638-643
    • Jones, T.R.1    Davis, C.2    Daniel, E.E.3
  • 50
    • 0025685169 scopus 로고
    • Reduced allergen-induced nasal congestion and leukotriene synthesis with an orally active 5-lipoxygenase inhibitor
    • Knapp HR. Reduced allergen-induced nasal congestion and leukotriene synthesis with an orally active 5-lipoxygenase inhibitor. N Engl J Med 1990;323:1745-8.
    • (1990) N Engl J Med , vol.323 , pp. 1745-1748
    • Knapp, H.R.1
  • 51
    • 0028990176 scopus 로고
    • The leukotriene D4-rcceptor antagonist, ICI 204.219, relieves symptoms of acute seasonal allergic rhinitis
    • Donnelly AL, Glass M, Minkwitz MC, Casale TB. The leukotriene D4-rcceptor antagonist, ICI 204.219, relieves symptoms of acute seasonal allergic rhinitis. Am J Respir Crit Care Med 1995;151:1734-9.
    • (1995) Am J Respir Crit Care Med , vol.151 , pp. 1734-1739
    • Donnelly, A.L.1    Glass, M.2    Minkwitz, M.C.3    Casale, T.B.4
  • 52
    • 0025904956 scopus 로고
    • Participation of the cysteinyl leukotrienes in the acute bronchoconstrictor response to inhaled platelet activating factor in man
    • Spencer DA, Evans JM, Green SE, Piper PJ, Costello JF. Participation of the cysteinyl leukotrienes in the acute bronchoconstrictor response to inhaled platelet activating factor in man. Thorax 1991;46:441-5.
    • (1991) Thorax , vol.46 , pp. 441-445
    • Spencer, D.A.1    Evans, J.M.2    Green, S.E.3    Piper, P.J.4    Costello, J.F.5
  • 53
    • 0031434804 scopus 로고    scopus 로고
    • The leukotriene receptor antagonist zafirlukast inhibits sulfur dioxide-induced bronchoconstriction in patients with asthma
    • Lazarus SC, Wong HH, Watts MJ, Boushey HA, Lavins BJ, Minkwitz MC. The leukotriene receptor antagonist zafirlukast inhibits sulfur dioxide-induced bronchoconstriction in patients with asthma. Am J Respir Crit Care Med 1997;156:1725-30.
    • (1997) Am J Respir Crit Care Med , vol.156 , pp. 1725-1730
    • Lazarus, S.C.1    Wong, H.H.2    Watts, M.J.3    Boushey, H.A.4    Lavins, B.J.5    Minkwitz, M.C.6
  • 54
    • 0026066945 scopus 로고
    • Effect of cysteinyl-leukotriene receptor antagonist ICI 204.219 on allergen-induced bronchoconstriction and airway hyperreactivity in atopic subjects
    • Taylor IK, O'Shaughnessy KM, Fuller RW, Dollery CT. Effect of cysteinyl-leukotriene receptor antagonist ICI 204.219 on allergen-induced bronchoconstriction and airway hyperreactivity in atopic subjects. Lancet 1991;337:690-4.
    • (1991) Lancet , vol.337 , pp. 690-694
    • Taylor, I.K.1    O'Shaughnessy, K.M.2    Fuller, R.W.3    Dollery, C.T.4
  • 55
    • 0030996540 scopus 로고    scopus 로고
    • Attenuation of early and late phase allergen-induced bronchoconstriction in asthmatic subjects by a 5-lipoxygenase activating protein antagonist, BAYx 1005
    • Hamilton AL, Watson RM, Wyile G, O'Byrne PM. Attenuation of early and late phase allergen-induced bronchoconstriction in asthmatic subjects by a 5-lipoxygenase activating protein antagonist, BAYx 1005. Thorax 1997;52:348-54.
    • (1997) Thorax , vol.52 , pp. 348-354
    • Hamilton, A.L.1    Watson, R.M.2    Wyile, G.3    O'Byrne, P.M.4
  • 56
    • 0026550488 scopus 로고
    • Role of leukotrienes in exercise-induced asthma: Inhibitory effect of ICI 204219, a potent leukotriene D4 receptor antagonist
    • Finnerty JP, Wood-Baker R, Thomson H, Holgate ST Role of leukotrienes in exercise-induced asthma: inhibitory effect of ICI 204219, a potent leukotriene D4 receptor antagonist. Am Rev Respir Dis 1992;145:746-9.
    • (1992) Am Rev Respir Dis , vol.145 , pp. 746-749
    • Finnerty, J.P.1    Wood-Baker, R.2    Thomson, H.3    Holgate, S.T.4
  • 58
    • 0029937854 scopus 로고    scopus 로고
    • Inhibition of exercise induced bronchospasm by zilcuton: A 5-lipoxygenase inhibitor
    • Meltzer SS, Hasday JD, Cohn J, Bleecker ER. Inhibition of exercise induced bronchospasm by zilcuton: a 5-lipoxygenase inhibitor. Am J Respir Crit Care Med 1996;153:931-5.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 931-935
    • Meltzer, S.S.1    Hasday, J.D.2    Cohn, J.3    Bleecker, E.R.4
  • 59
    • 0025647031 scopus 로고
    • The effects of a 5-lipoxygenase inhibitor on asthma induced by cold, dry air
    • Israel E, Dermarkarian R, Rosenberg M, et al. The effects of a 5-lipoxygenase inhibitor on asthma induced by cold, dry air. N Engl J Med 1990;323:1740-4.
    • (1990) N Engl J Med , vol.323 , pp. 1740-1744
    • Israel, E.1    Dermarkarian, R.2    Rosenberg, M.3
  • 60
    • 0025951165 scopus 로고
    • The potent and selective sulfidopep tide leukotriene antagonist, SK&F 104353, inhibits aspirin-induced asthma
    • Christie PE, Smith CM, Lee TH. The potent and selective sulfidopep tide leukotriene antagonist, SK&F 104353, inhibits aspirin-induced asthma. Am Rev Respir Dis 1991;144:957-8.
    • (1991) Am Rev Respir Dis , vol.144 , pp. 957-958
    • Christie, P.E.1    Smith, C.M.2    Lee, T.H.3
  • 61
    • 0027172447 scopus 로고
    • The leukotriene-receptor antagonist MK-0679 blocks airway obstruction induced by inhaled lysine-aspirin in aspirin sensitive asthmatics
    • Dahlen B, Kumlin M, Margolskee DJ, et al. The leukotriene-receptor antagonist MK-0679 blocks airway obstruction induced by inhaled lysine-aspirin in aspirin sensitive asthmatics. Eur Respir J 1993;6:1018-26.
    • (1993) Eur Respir J , vol.6 , pp. 1018-1026
    • Dahlen, B.1    Kumlin, M.2    Margolskee, D.J.3
  • 62
    • 0028114047 scopus 로고
    • Effect of the 5-lipoxygenase inhibitor ZD2138 on aspirin-induced asthma
    • Nassar SM, Bell GS, Foster S, et al. Effect of the 5-lipoxygenase inhibitor ZD2138 on aspirin-induced asthma. Thorax 1994;49:749-56.
    • (1994) Thorax , vol.49 , pp. 749-756
    • Nassar, S.M.1    Bell, G.S.2    Foster, S.3
  • 63
    • 0027762572 scopus 로고
    • The pivotal role of 5-lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin
    • Israel E, Fischer AR, Rosenberg MA, et al. The pivotal role of 5-lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin. Am Rev Respir Dis 1993;148:1447-51.
    • (1993) Am Rev Respir Dis , vol.148 , pp. 1447-1451
    • Israel, E.1    Fischer, A.R.2    Rosenberg, M.A.3
  • 66
    • 0019949885 scopus 로고
    • Allergen-induced increase in bronchial responsiveness to histamine: Relationship to the late asthmatic response and change in airway caliber
    • Cartier A, Thomson NC, Frith PA, Roberts R, Hargreave FE. Allergen-induced increase in bronchial responsiveness to histamine: relationship to the late asthmatic response and change in airway caliber. J Allergy Clin Immunol 1982;70:170-7
    • (1982) J Allergy Clin Immunol , vol.70 , pp. 170-177
    • Cartier, A.1    Thomson, N.C.2    Frith, P.A.3    Roberts, R.4    Hargreave, F.E.5
  • 67
    • 0026610937 scopus 로고
    • Leukotriene D4 receptor blockade inhibits the immediate and late bronchoconstrictor responses to inhaled antigen in patients with asthma
    • Rasmussen JB, Eriksson LO, Margolskec DJ, Tagari P, Williams VC, Andersson KE. Leukotriene D4 receptor blockade inhibits the immediate and late bronchoconstrictor responses to inhaled antigen in patients with asthma. J Allergy Clin Immunol 1992;90:193-201.
    • (1992) J Allergy Clin Immunol , vol.90 , pp. 193-201
    • Rasmussen, J.B.1    Eriksson, L.O.2    Margolskec, D.J.3    Tagari, P.4    Williams, V.C.5    Andersson, K.E.6
  • 68
    • 0027458882 scopus 로고
    • Oral leukotriene inhibitor (MK-886) blocks allergen-induced airway responses
    • Friedman BS, Bel EH, Buntinx A, et al. Oral leukotriene inhibitor (MK-886) blocks allergen-induced airway responses. Am Rev Respir Dis 1993;147:839-44.
    • (1993) Am Rev Respir Dis , vol.147 , pp. 839-844
    • Friedman, B.S.1    Bel, E.H.2    Buntinx, A.3
  • 69
    • 0028821025 scopus 로고
    • The effect of MK-0591, a novel 5-lipoxygenase activating protein inhibitor, on leukotriene biosynthesis and allergen-induced airway responses in asthmatic subjects in vivo
    • Diamant Z, Timmers MC, van der Veen H, et al. The effect of MK-0591, a novel 5-lipoxygenase activating protein inhibitor, on leukotriene biosynthesis and allergen-induced airway responses in asthmatic subjects in vivo. J Allergy Clin Immunol 1995;95:42-51.
    • (1995) J Allergy Clin Immunol , vol.95 , pp. 42-51
    • Diamant, Z.1    Timmers, M.C.2    Van Der Veen, H.3
  • 70
    • 0030944646 scopus 로고    scopus 로고
    • Combined antagonism of leukotricnes and histamine produces predominant inhibition of allergen-induced early and late phase airway obstruction in asthmatics
    • Roquet A, Dahlen B, Kumlin M, et al. Combined antagonism of leukotricnes and histamine produces predominant inhibition of allergen-induced early and late phase airway obstruction in asthmatics. Am J Respir Crit Care Med 1997;155:1856-63.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 1856-1863
    • Roquet, A.1    Dahlen, B.2    Kumlin, M.3
  • 72
    • 0030902575 scopus 로고    scopus 로고
    • The effect of inhaled leukotriene D4 and methacholine on sputum cell differentials in asthma
    • Diamant Z, Hiltermann JT, van Rensen EL, et al. The effect of inhaled leukotriene D4 and methacholine on sputum cell differentials in asthma. Am J Respir Crit Care Med 1997;155:1247-53.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 1247-1253
    • Diamant, Z.1    Hiltermann, J.T.2    Van Rensen, E.L.3
  • 73
    • 0030033328 scopus 로고    scopus 로고
    • A controlled trial of the effect of the 5-lipoxygenase inhibitor, zileuton, on lung inflammation produced by segmental antigen challenge in human beings
    • Kane GC, Pollice M, Kim CJ, et al. A controlled trial of the effect of the 5-lipoxygenase inhibitor, zileuton, on lung inflammation produced by segmental antigen challenge in human beings. J Allergy Clin Immunol 1996;97:646-54.
    • (1996) J Allergy Clin Immunol , vol.97 , pp. 646-654
    • Kane, G.C.1    Pollice, M.2    Kim, C.J.3
  • 74
    • 0031800910 scopus 로고    scopus 로고
    • Effect of zafirlukast (Accolate) on cellular mediators of inflammation: Bronchoalveolar lavage fluid findings after segmental antigen challenge
    • Calhoun WJ, Lavins BJ, Minkwitz MC, Evans R, Gleich GJ, Cohn J. Effect of zafirlukast (Accolate) on cellular mediators of inflammation: bronchoalveolar lavage fluid findings after segmental antigen challenge. Am J Respir Crit Care Med 1998;157:1381-9.
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 1381-1389
    • Calhoun, W.J.1    Lavins, B.J.2    Minkwitz, M.C.3    Evans, R.4    Gleich, G.J.5    Cohn, J.6
  • 75
    • 0021256371 scopus 로고
    • Is there a unifying hypothesis for exercise-induced asth-ma?
    • Anderson SD. Is there a unifying hypothesis for exercise-induced asth-ma? J Allergy Clin Immunol 1984;73:660-5.
    • (1984) J Allergy Clin Immunol , vol.73 , pp. 660-665
    • Anderson, S.D.1
  • 76
    • 0023194660 scopus 로고
    • Immediate and delayed bronchoconstriction after exercise in patients with asthma
    • Rubinstein I, Levison H, Slutsky AS, et al. Immediate and delayed bronchoconstriction after exercise in patients with asthma. N Engl J Med 1987;317:482-5.
    • (1987) N Engl J Med , vol.317 , pp. 482-485
    • Rubinstein, I.1    Levison, H.2    Slutsky, A.S.3
  • 77
    • 0026610949 scopus 로고
    • Urinary leukotriene E4 after exercise challenge in children with asthma
    • Kikawa Y, Miyanomae T, Inoue Y, et al. Urinary leukotriene E4 after exercise challenge in children with asthma. J Allergy Clin Immunol 1992; 89:1111-9
    • (1992) J Allergy Clin Immunol , vol.89 , pp. 1111-1119
    • Kikawa, Y.1    Miyanomae, T.2    Inoue, Y.3
  • 78
    • 0030696614 scopus 로고    scopus 로고
    • Increased urinary excretion of LTE4 after exercise and attenuation of exercise-induced bronchospasm by montelukast, a cysteinyl leukotriene receptor antagonist
    • Reiss TF, Hill JB, Harman E, et al. Increased urinary excretion of LTE4 after exercise and attenuation of exercise-induced bronchospasm by montelukast, a cysteinyl leukotriene receptor antagonist. Thorax 1997;52: 1030-5.
    • (1997) Thorax , vol.52 , pp. 1030-1035
    • Reiss, T.F.1    Hill, J.B.2    Harman, E.3
  • 81
    • 0021684478 scopus 로고
    • Diagnosis, prevention, and treatment of adverse reactions to aspirin and nonsteroidal anti-inflammatory drugs
    • Stevenson DD. Diagnosis, prevention, and treatment of adverse reactions to aspirin and nonsteroidal anti-inflammatory drugs. J Allergy Clin Immunol 1984;74:617-22.
    • (1984) J Allergy Clin Immunol , vol.74 , pp. 617-622
    • Stevenson, D.D.1
  • 82
    • 0032519008 scopus 로고    scopus 로고
    • Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma
    • Cowburn AS, Sladek K, Soja J, et al. Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma. J Clin Invest 1998;101:834-46.
    • (1998) J Clin Invest , vol.101 , pp. 834-846
    • Cowburn, A.S.1    Sladek, K.2    Soja, J.3
  • 83
    • 0031590522 scopus 로고    scopus 로고
    • 4 synthase promoter polymorphism and risk of aspirin-induced asthma
    • 4 synthase promoter polymorphism and risk of aspirin-induced asthma. Lancet 1997;350:1599-600.
    • (1997) Lancet , vol.350 , pp. 1599-1600
    • Sanak, M.1    Simon, H.U.2    Szczeklik, A.3
  • 84
    • 0026644731 scopus 로고
    • Urinary excretion of leukotriene E4 and 11-dehydro-thromboxane B2 in response to bronchial provocations with allergen, aspirin, leukotriene D4, and histamine in asthmatics
    • Kumlin M, Dahlen B, Bjorck T, Zetterstrom O, Granstrom E, Dahlen SE. Urinary excretion of leukotriene E4 and 11-dehydro-thromboxane B2 in response to bronchial provocations with allergen, aspirin, leukotriene D4, and histamine in asthmatics. Am Rev Respir Dis 1992;146:96-103.
    • (1992) Am Rev Respir Dis , vol.146 , pp. 96-103
    • Kumlin, M.1    Dahlen, B.2    Bjorck, T.3    Zetterstrom, O.4    Granstrom, E.5    Dahlen, S.E.6
  • 85
    • 0025892285 scopus 로고
    • Urinary leukotriene E4 concentrations increase after aspirin challenge in aspirin-sensitive asthmatic subjects
    • Christie PE, Tagari P, Ford-Hutchinson AW, et al. Urinary leukotriene E4 concentrations increase after aspirin challenge in aspirin-sensitive asthmatic subjects. Am Rev Respir Dis 1991;143:1025-9.
    • (1991) Am Rev Respir Dis , vol.143 , pp. 1025-1029
    • Christie, P.E.1    Tagari, P.2    Ford-Hutchinson, A.W.3
  • 86
    • 0026526828 scopus 로고
    • Increased excretion of leukotriene E4 during aspirin-induced asthma
    • Knapp HR, Sladek K, Fitzgerald GA. Increased excretion of leukotriene E4 during aspirin-induced asthma. J Lab Clin Med 1992;119:48-51.
    • (1992) J Lab Clin Med , vol.119 , pp. 48-51
    • Knapp, H.R.1    Sladek, K.2    Fitzgerald, G.A.3
  • 87
    • 0027725249 scopus 로고
    • Effect of the leukotriene receptor antagonist MK-0679 on baseline pulmonary function in aspirin sensitive asthmatic subjects
    • Dahlen B, Margolskee DJ, Zetterstrom O, Dahlen SE. Effect of the leukotriene receptor antagonist MK-0679 on baseline pulmonary function in aspirin sensitive asthmatic subjects. Thorax 1993;48:1205-10.
    • (1993) Thorax , vol.48 , pp. 1205-1210
    • Dahlen, B.1    Margolskee, D.J.2    Zetterstrom, O.3    Dahlen, S.E.4
  • 88
    • 0030872408 scopus 로고    scopus 로고
    • Pranlukast, a novel leukotriene receptor antagonist: Results of the first European, placebo controlled, multicentre clinical study in asthma
    • Barnes NC, Pujet JC. Pranlukast, a novel leukotriene receptor antagonist: results of the first European, placebo controlled, multicentre clinical study in asthma. Thorax 1997;52:523-7
    • (1997) Thorax , vol.52 , pp. 523-527
    • Barnes, N.C.1    Pujet, J.C.2
  • 90
    • 0029970797 scopus 로고    scopus 로고
    • Effects of montelukast (MK-0476), a new potent cysteinyl leukotriene (LTD4) receptor antagonist, in patients with chronic asthma
    • Reiss TF, Altman LC, Chervinsky P, et al. Effects of montelukast (MK-0476), a new potent cysteinyl leukotriene (LTD4) receptor antagonist, in patients with chronic asthma. J Allergy Clin Immunol 1996;98:528-34.
    • (1996) J Allergy Clin Immunol , vol.98 , pp. 528-534
    • Reiss, T.F.1    Altman, L.C.2    Chervinsky, P.3
  • 91
    • 0027369276 scopus 로고
    • The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma
    • Israel E, Rubin P, Kemp JP, et al. The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma. Ann Intern Med 1993; 119:1059-66.
    • (1993) Ann Intern Med , vol.119 , pp. 1059-1066
    • Israel, E.1    Rubin, P.2    Kemp, J.P.3
  • 92
    • 0029915834 scopus 로고    scopus 로고
    • Effect of treatment with zileuton, a 5-lipoxygenase inhibitor, in patients with asthma: A randomized controlled trial
    • Israel E, Cohn J, Dube L, Drazen JM. Effect of treatment with zileuton, a 5-lipoxygenase inhibitor, in patients with asthma: a randomized controlled trial. JAMA 1996;275:931-6.
    • (1996) JAMA , vol.275 , pp. 931-936
    • Israel, E.1    Cohn, J.2    Dube, L.3    Drazen, J.M.4
  • 93
    • 0029853741 scopus 로고    scopus 로고
    • Acute and chronic effects of a 5-liopxygenase inhibitor in asthma: A 6-month randomized multicenter trial
    • Liu MC, Dube LM, Lancaster J. Acute and chronic effects of a 5-liopxygenase inhibitor in asthma: a 6-month randomized multicenter trial. J Allergy Clin Immunol 1996;98:859-71.
    • (1996) J Allergy Clin Immunol , vol.98 , pp. 859-871
    • Liu, M.C.1    Dube, L.M.2    Lancaster, J.3
  • 94
    • 0032496618 scopus 로고    scopus 로고
    • Montelukast, a once-daily leukotriene receptor antagonist, in the treatment of chronic asthma: A multicenter, randomized, double blind trial
    • Reiss TF, Chervinsky P, Dockhorn RJ, Shingo S, Seidenberg B, Edwards TB. Montelukast, a once-daily leukotriene receptor antagonist, in the treatment of chronic asthma: a multicenter, randomized, double blind trial. Arch Intern Med 1998;158:1213-20.
    • (1998) Arch Intern Med , vol.158 , pp. 1213-1220
    • Reiss, T.F.1    Chervinsky, P.2    Dockhorn, R.J.3    Shingo, S.4    Seidenberg, B.5    Edwards, T.B.6
  • 95
    • 0031660267 scopus 로고    scopus 로고
    • Montelukast once daily inhibits exercise induced bronchoconstriction in 6 to 14-year-old children with asthma
    • Kemp JP, Dockhorn RJ, Shapiro GG, et al. Montelukast once daily inhibits exercise induced bronchoconstriction in 6 to 14-year-old children with asthma. J Pediatr 1998;133:424-8.
    • (1998) J Pediatr , vol.133 , pp. 424-428
    • Kemp, J.P.1    Dockhorn, R.J.2    Shapiro, G.G.3
  • 96
    • 0032522735 scopus 로고    scopus 로고
    • Montelukast for chronic asthma in 6- to 14-year-old children: A randomized, double-blind trial
    • Knorr B, Matz I, Bernstein JA, et al. Montelukast for chronic asthma in 6- to 14-year-old children: a randomized, double-blind trial. JAMA 1998;279:1181-6.
    • (1998) JAMA , vol.279 , pp. 1181-1186
    • Knorr, B.1    Matz, I.2    Bernstein, J.A.3
  • 97
    • 0031835681 scopus 로고    scopus 로고
    • Montelukast, a potent leukotriene receptor antagonist, causes dose-related improvements in chronic asthma
    • Noonan MJ, Chervinsky P, Brandon M. Montelukast, a potent leukotriene receptor antagonist, causes dose-related improvements in chronic asthma. Eur Respir J 1998;11:1232-9.
    • (1998) Eur Respir J , vol.11 , pp. 1232-1239
    • Noonan, M.J.1    Chervinsky, P.2    Brandon, M.3
  • 99
    • 0004002716 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of asthma
    • Bethesda, Md.: National Asthma Education Program, April (NIH publication no. 97-4051.)
    • Guidelines for the diagnosis and treatment of asthma. Expert panel report 2. Clinical practice guidelines. Bethesda, Md.: National Asthma Education Program, April 1997. (NIH publication no. 97-4051.)
    • (1997) Expert Panel Report 2. Clinical Practice Guidelines , vol.2
  • 100
    • 0025802839 scopus 로고
    • Lung function improvement in asthma with a cysteinyl-leukotriene receptor antagonist
    • Hui KP, Barnes NC. Lung function improvement in asthma with a cysteinyl-leukotriene receptor antagonist. Lancet 1991;337:1062-3.
    • (1991) Lancet , vol.337 , pp. 1062-1063
    • Hui, K.P.1    Barnes, N.C.2
  • 101
    • 0030903255 scopus 로고    scopus 로고
    • Leukotriene antagonist prevents exacerbation of asthma during reduction of high-dose inhaled corticosteroid
    • Tamaoki J, Kondo M, Sakai N, et al. Leukotriene antagonist prevents exacerbation of asthma during reduction of high-dose inhaled corticosteroid. Am J Respir Crit Care Med 1997;155:1235-40.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 1235-1240
    • Tamaoki, J.1    Kondo, M.2    Sakai, N.3
  • 102
    • 0004070956 scopus 로고    scopus 로고
    • West Point, Pa.: Merck, (package insert)
    • Singulair (montelukast sodium). West Point, Pa.: Merck, 1998 (package insert).
    • (1998) Singulair (Montelukast Sodium)
  • 103
    • 0029113871 scopus 로고
    • Effect of chronic 5-lipoxygenase inhibition on airway hyperresponsiveness in asthmatic subjects
    • Fischer AR, McFadden CA, Frantz R, et al. Effect of chronic 5-lipoxygenase inhibition on airway hyperresponsiveness in asthmatic subjects. Am J Respir Crit Care Med 1995;152:1203-7.
    • (1995) Am J Respir Crit Care Med , vol.152 , pp. 1203-1207
    • Fischer, A.R.1    McFadden, C.A.2    Frantz, R.3
  • 104
    • 0031964913 scopus 로고    scopus 로고
    • A randomized controlled trial comparing zileuton with theophylline in moderate asthma
    • Schwartz HJ, Petty T, Dube LM, Swanson LJ, Lancaster JF. A randomized controlled trial comparing zileuton with theophylline in moderate asthma. Arch Intern Med 1998;158:141-8
    • (1998) Arch Intern Med , vol.158 , pp. 141-148
    • Schwartz, H.J.1    Petty, T.2    Dube, L.M.3    Swanson, L.J.4    Lancaster, J.F.5
  • 105
    • 6844250776 scopus 로고    scopus 로고
    • Pulmonary infiltrates, eosinophilia, and cardiomyopathy following corticosteroid withdrawal in patients with asthma receiving zafirlukast
    • Wechsler ME, Garpestad E, Flier SR, et al. Pulmonary infiltrates, eosinophilia, and cardiomyopathy following corticosteroid withdrawal in patients with asthma receiving zafirlukast. JAMA 1998;279:455-7.
    • (1998) JAMA , vol.279 , pp. 455-457
    • Wechsler, M.E.1    Garpestad, E.2    Flier, S.R.3
  • 106
    • 0005415518 scopus 로고    scopus 로고
    • ZYFLO filmtab
    • Montvale, N.J.: Medical Economics
    • ZYFLO filmtab. In: Physicians' desk reference. 52nd ed. Montvale, N.J.: Medical Economics, 1998:474-6.
    • (1998) Physicians' Desk Reference. 52nd Ed. , pp. 474-476
  • 107
    • 0025141037 scopus 로고
    • Guidelines for management of asthma in adults. 1. Chronic persistent asthma: Statement by the British Thoracic Society, Research Unit of the Royal College of Physicians of London, King's Fund Centre, National Asthma Campaign
    • Erratum, BMJ 1990;301: 924
    • Guidelines for management of asthma in adults. 1. Chronic persistent asthma: statement by the British Thoracic Society, Research Unit of the Royal College of Physicians of London, King's Fund Centre, National Asthma Campaign. BMJ 1990;301:651-3. [Erratum, BMJ 1990;301: 924.]
    • (1990) BMJ , vol.301 , pp. 651-653
  • 108
    • 0345110516 scopus 로고
    • Executive summary: Guidelines for the diagnosis and management of asthma
    • Bethesda, Md.: National Asthma Education Program, June (NIH publication no. 91-3042A.)
    • Executive summary: guidelines for the diagnosis and management of asthma. Expert Panel report. Bethesda, Md.: National Asthma Education Program, June 1991. (NIH publication no. 91-3042A.)
    • (1991) Expert Panel Report
  • 109
    • 18744421762 scopus 로고    scopus 로고
    • Montelukast, a leukotriene-receptor antagonist, for the treatment of mild asthma and exercise-induced bronchoconstriction
    • Leff JA, Busse WW, Pearlman D, et al. Montelukast, a leukotriene-receptor antagonist, for the treatment of mild asthma and exercise-induced bronchoconstriction. N Engl J Med 1998;339:147-52.
    • (1998) N Engl J Med , vol.339 , pp. 147-152
    • Leff, J.A.1    Busse, W.W.2    Pearlman, D.3
  • 110
    • 0028341327 scopus 로고
    • Comparison of patients' compliance with prescribed oral and inhaled asthma medications
    • Kelloway JS, Wyatt RA, Adlis SA. Comparison of patients' compliance with prescribed oral and inhaled asthma medications. Arch Intern Med 1994;154:1349-52.
    • (1994) Arch Intern Med , vol.154 , pp. 1349-1352
    • Kelloway, J.S.1    Wyatt, R.A.2    Adlis, S.A.3


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