Discovery and pre-clinical development of antithrombotics from hematophagous invertebrates

Current Medicinal Chemistry: Cardiovascular and Hematological Agents

Volumn 3, Issue 1, 2005, Pages 1-10

  Ledizet, Michel ^a   Harrison, Lisa M ^b   Koski, Raymond A ^a   Cappello, Michael ^b  

^a L2 Diagnostics LLC   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Anticoagulants; Cardiovascular disease; Coagulation; Parasites; Platelets; Restenosis; Stroke; Thrombosis; Vascular biology; Vector biology

Indexed keywords

AMERICANIN; ANGIOMASK; ANTICOAGULANT AGENT; ANTICOAGULANT PROTEIN; ANTISTASIN; ANTITHROMBOCYTIC AGENT; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 10A INHIBITOR; BLOOD CLOTTING FACTOR 13A; BLOOD CLOTTING FACTOR 7A; BLOOD CLOTTING FACTOR 7A INHIBITOR; BLOOD CLOTTING INHIBITOR; BOOPHILIN; DESULFATOHIRUDIN; DISAGREGIN; FIBRINOGEN RECEPTOR ANTAGONIST; HEPARIN; HIRUDIN; HIRULOG; IPRIVASK; IXOLARIS; LEPIRUDIN; MADANIN; MOUBATIN; ORNITHODORIN; SAVIGNIN; THROMBIN; THROMBIN INHIBITOR; TICK ANTICOAGULANT PEPTIDE; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; VARIABILIN;

AMBLYOMMA; ANCYLOSTOMA CANINUM; ANCYLOSTOMA CEYLANICUM; ANOPHELES; ARTERY THROMBOSIS; BABOON; BLOOD CLOTTING; BOOPHILUS MICROPLUS; CHRYSOPHYTA; CLINICAL TRIAL; CORONARY ARTERY THROMBOSIS; DEEP VEIN THROMBOSIS; DERMACENTOR; DISEASE ASSOCIATION; DOG; DRUG ABSORPTION; DRUG APPROVAL; DRUG EFFICACY; DRUG HALF LIFE; DRUG MECHANISM; DRUG POTENCY; DRUG RESEARCH; DRUG SCREENING; DRUG TARGETING; FOOD AND DRUG ADMINISTRATION; GLOSSINA MORSITANS; HEART DISEASE; HEPARIN INDUCED THROMBOCYTOPENIA; HUMAN; IN VIVO STUDY; INVERTEBRATE; LEECH; MALIGNANT NEOPLASTIC DISEASE; MAMMAL; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE; POSTOPERATIVE THROMBOSIS; RABBIT; RAT; RESTENOSIS; REVIEW; RHODNIUS; SPECIES DIFFERENCE; STROKE; SWINE; THROMBOCYTE AGGREGATION INHIBITION; THROMBOCYTE FUNCTION; THROMBOSIS PREVENTION; TICK; TOTAL HIP PROSTHESIS; TOTAL KNEE REPLACEMENT; TRANSLUMINAL CORONARY ANGIOPLASTY; TRIATOMA; TRIATOMA INFESTANS; UNITED STATES; UNSTABLE ANGINA PECTORIS; VEIN THROMBOSIS;

ANCYLOSTOMATOIDEA; ANIMALS; ANTICOAGULANTS; BIOLOGICAL PRODUCTS; BLOOD COAGULATION FACTOR INHIBITORS; DRUG EVALUATION, PRECLINICAL; FIBRINOLYTIC AGENTS; HUMANS; INVERTEBRATES; LEECHES; PLATELET AGGREGATION INHIBITORS; THROMBOSIS; TICKS;

EID: 11244280989     PISSN: 15680169     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568016052773315     Document Type: Review

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