메뉴 건너뛰기




Volumn 110, Issue 2-3, 2003, Pages 73-82

Management of heparin-induced thrombocytopenia: A critical comparison of lepirudin and argatroban

Author keywords

Anticoagulation; Argatroban; Direct thrombin inhibitor; Heparin induced thrombocytopenia; Lepirudin; Thrombosis; Warfarin induced necrosis

Indexed keywords

ARGATROBAN; COUMARIN; DANAPAROID; FIBRIN; HEPARIN; LEPIRUDIN; THROMBIN INHIBITOR; WARFARIN;

EID: 0142258733     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(03)00336-0     Document Type: Review
Times cited : (98)

References (38)
  • 1
    • 0038392539 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: Pathogenesis and management
    • Warkentin T.E. Heparin-induced thrombocytopenia: pathogenesis and management. Br. J. Haematol. 121:2003;535-555.
    • (2003) Br. J. Haematol. , vol.121 , pp. 535-555
    • Warkentin, T.E.1
  • 2
    • 0036733708 scopus 로고    scopus 로고
    • Venous limb gangrene during overlapping therapy with warfarin and a direct thrombin inhibitor for immune heparin-induced thrombocytopenia
    • Smythe M.A., Warkentin T.E., Stephens J.L., Zakalik D., Mattson J.C. Venous limb gangrene during overlapping therapy with warfarin and a direct thrombin inhibitor for immune heparin-induced thrombocytopenia. Am. J. Hematol. 71:2002;50-52.
    • (2002) Am. J. Hematol. , vol.71 , pp. 50-52
    • Smythe, M.A.1    Warkentin, T.E.2    Stephens, J.L.3    Zakalik, D.4    Mattson, J.C.5
  • 3
    • 0037610515 scopus 로고    scopus 로고
    • An improved definition of immune heparin-induced thrombocytopenia in postoperative orthopedic patients
    • [in press]
    • Warkentin T.E., Roberts R.S., Hirsh J., Kelton J.G. An improved definition of immune heparin-induced thrombocytopenia in postoperative orthopedic patients. Arch. Intern. Med. 2003;. [in press].
    • (2003) Arch. Intern. Med.
    • Warkentin, T.E.1    Roberts, R.S.2    Hirsh, J.3    Kelton, J.G.4
  • 4
    • 0035953702 scopus 로고    scopus 로고
    • Temporal aspects of heparin-induced thrombocytopenia
    • Warkentin T.E., Kelton J.G. Temporal aspects of heparin-induced thrombocytopenia. N. Engl. J. Med. 344:2001;1286-1292.
    • (2001) N. Engl. J. Med. , vol.344 , pp. 1286-1292
    • Warkentin, T.E.1    Kelton, J.G.2
  • 5
    • 0036881566 scopus 로고    scopus 로고
    • Platelet count monitoring and laboratory testing for heparin-induced thrombocytopenia
    • Warkentin T.E. Platelet count monitoring and laboratory testing for heparin-induced thrombocytopenia. Arch. Pathol. Lab. Med. 126:2002;1415-1423.
    • (2002) Arch. Pathol. Lab. Med. , vol.126 , pp. 1415-1423
    • Warkentin, T.E.1
  • 6
    • 0029035681 scopus 로고
    • Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin
    • Warkentin T.E., Levine M.N., Hirsh J., Horsewood P., Roberts R.S., Gent M.et al. Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin. N. Engl. J. Med. 332:1995;1330-1335.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1330-1335
    • Warkentin, T.E.1    Levine, M.N.2    Hirsh, J.3    Horsewood, P.4    Roberts, R.S.5    Gent, M.6
  • 7
    • 0002353110 scopus 로고    scopus 로고
    • Clinical picture of heparin-induced thrombocytopenia
    • T.E. Warkentin, & A. Greinacher. New York: Marcel Dekker
    • Warkentin T.E. Clinical picture of heparin-induced thrombocytopenia. Warkentin T.E., Greinacher A. Heparin-induced thrombocytopenia. 2nd ed. 2001;43-86 Marcel Dekker, New York.
    • (2001) Heparin-induced Thrombocytopenia 2nd Ed. , pp. 43-86
    • Warkentin, T.E.1
  • 8
    • 0037905743 scopus 로고    scopus 로고
    • Central venous catheters and upper-extremity deep-vein thrombosis complicating immune heparin-induced thrombocytopenia
    • Hong A.P., Cook D.J., Sigouin C.S., Warkentin T.E. Central venous catheters and upper-extremity deep-vein thrombosis complicating immune heparin-induced thrombocytopenia. Blood. 101:2003;3049-3051.
    • (2003) Blood , vol.101 , pp. 3049-3051
    • Hong, A.P.1    Cook, D.J.2    Sigouin, C.S.3    Warkentin, T.E.4
  • 9
    • 0038243178 scopus 로고    scopus 로고
    • The incidence of heparin-induced thrombocytopenia in hospitalized medical patients treated with subcutaneous unfractionated heparin: A prospective cohort study
    • Girolami B., Prandoni P., Stefani P.M., Tanduo C., Sabbion P., Eichler P.et al. The incidence of heparin-induced thrombocytopenia in hospitalized medical patients treated with subcutaneous unfractionated heparin: a prospective cohort study. Blood. 101:2003;2955-2959.
    • (2003) Blood , vol.101 , pp. 2955-2959
    • Girolami, B.1    Prandoni, P.2    Stefani, P.M.3    Tanduo, C.4    Sabbion, P.5    Eichler, P.6
  • 10
    • 0030281338 scopus 로고    scopus 로고
    • A 14-year study of heparin-induced thrombocytopenia
    • Warkentin T.E., Kelton J.G. A 14-year study of heparin-induced thrombocytopenia. Am. J. Med. 101:1996;502-507.
    • (1996) Am. J. Med. , vol.101 , pp. 502-507
    • Warkentin, T.E.1    Kelton, J.G.2
  • 11
    • 0033029056 scopus 로고    scopus 로고
    • Failure of early heparin cessation as treatment for heparin-induced thrombocytopenia
    • Wallis D.E., Workman D.L., Lewis B.E., Steen L., Pifarre R., Moran J.F. Failure of early heparin cessation as treatment for heparin-induced thrombocytopenia. Am. J. Med. 106:1999;629-635.
    • (1999) Am. J. Med. , vol.106 , pp. 629-635
    • Wallis, D.E.1    Workman, D.L.2    Lewis, B.E.3    Steen, L.4    Pifarre, R.5    Moran, J.F.6
  • 14
    • 0032826601 scopus 로고    scopus 로고
    • Lower limb veins should be systematically explored in patients with isolated heparin-induced thrombocytopenia
    • [letter]
    • Tardy B., Tardy-Poncet B., Fournel P., Venet C., Jospe R., Dacosta A. Lower limb veins should be systematically explored in patients with isolated heparin-induced thrombocytopenia. [letter] Thromb. Haemost. 82:1999;1199-1200.
    • (1999) Thromb. Haemost. , vol.82 , pp. 1199-1200
    • Tardy, B.1    Tardy-Poncet, B.2    Fournel, P.3    Venet, C.4    Jospe, R.5    Dacosta, A.6
  • 15
    • 0034254793 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia with thromboembolic complications: Meta-analysis of 2 prospective trials to assess the value of parenteral treatment with lepirudin and its therapeutic aPTT range
    • Greinacher A., Eichler P., Lubenow N., Kwasny H., Luz M. Heparin-induced thrombocytopenia with thromboembolic complications: meta-analysis of 2 prospective trials to assess the value of parenteral treatment with lepirudin and its therapeutic aPTT range. Blood. 96:2000;846-851.
    • (2000) Blood , vol.96 , pp. 846-851
    • Greinacher, A.1    Eichler, P.2    Lubenow, N.3    Kwasny, H.4    Luz, M.5
  • 16
    • 0037705943 scopus 로고    scopus 로고
    • Results of the third prospective study of treatment with lepirudin in patients with heparin-induced thrombocytopenia (HAT)
    • [abstract]
    • Eichler P., Lubenow N., Greinacher A. Results of the third prospective study of treatment with lepirudin in patients with heparin-induced thrombocytopenia (HAT). [abstract] Blood. 100(Suppl. 1):2002;704a.
    • (2002) Blood , vol.100 , Issue.SUPPL. 1
    • Eichler, P.1    Lubenow, N.2    Greinacher, A.3
  • 17
    • 0038326320 scopus 로고    scopus 로고
    • Meta-analysis of three prospective studies of lepirudin in the prevention of thrombosis in patients with heparin-induced thrombocytopenia
    • [abstract]
    • Lubenow N., Eichler P., Leitz T., Greinacher A. Meta-analysis of three prospective studies of lepirudin in the prevention of thrombosis in patients with heparin-induced thrombocytopenia. [abstract] Blood. 100(Suppl. 1):2002;501a-502a.
    • (2002) Blood , vol.100 , Issue.SUPPL. 1
    • Lubenow, N.1    Eichler, P.2    Leitz, T.3    Greinacher, A.4
  • 18
    • 0038043835 scopus 로고    scopus 로고
    • Results of a large drug monitoring program confirms the safety and efficacy of Refludan (lepirudin) in patients with immune-mediated heparin-induced thrombocytopenia
    • [abstract]
    • Lubenow N., Eichler P., Greinacher A. Results of a large drug monitoring program confirms the safety and efficacy of Refludan (lepirudin) in patients with immune-mediated heparin-induced thrombocytopenia. [abstract] Blood. 100(Suppl. 1):2002;502a.
    • (2002) Blood , vol.100 , Issue.SUPPL. 1
    • Lubenow, N.1    Eichler, P.2    Greinacher, A.3
  • 19
    • 0345369740 scopus 로고    scopus 로고
    • Recombinant hirudin (lepirudin) provides safe and effective anticoagulation in patients with heparin-induced thrombocytopenia. A prospective study
    • Greinacher A., Völpel H., Janssens U., Hach-Wunderle V., Kemkes-Matthes B., Eichler P.et al. Recombinant hirudin (lepirudin) provides safe and effective anticoagulation in patients with heparin-induced thrombocytopenia. A prospective study. Circulation. 99:1999;73-80.
    • (1999) Circulation , vol.99 , pp. 73-80
    • Greinacher, A.1    Völpel, H.2    Janssens, U.3    Hach-Wunderle, V.4    Kemkes-Matthes, B.5    Eichler, P.6
  • 20
    • 0033543081 scopus 로고    scopus 로고
    • Lepirudin (recombinant hirudin) for parenteral anticoagulation in patients with heparin-induced thrombocytopenia
    • Greinacher A., Janssens U., Berg G., Bock M., Kwasny H., Kemkes-Matthes B.et al. Lepirudin (recombinant hirudin) for parenteral anticoagulation in patients with heparin-induced thrombocytopenia. Circulation. 100:1999;587-593.
    • (1999) Circulation , vol.100 , pp. 587-593
    • Greinacher, A.1    Janssens, U.2    Berg, G.3    Bock, M.4    Kwasny, H.5    Kemkes-Matthes, B.6
  • 21
    • 0034966778 scopus 로고    scopus 로고
    • A comparison of danaparoid and lepirudin in heparin-induced thrombocytopenia
    • Farner B., Eichler P., Kroll H., Greinacher A. A comparison of danaparoid and lepirudin in heparin-induced thrombocytopenia. Thromb. Haemost. 85:2001;950-957.
    • (2001) Thromb. Haemost. , vol.85 , pp. 950-957
    • Farner, B.1    Eichler, P.2    Kroll, H.3    Greinacher, A.4
  • 22
    • 0035167688 scopus 로고    scopus 로고
    • Prospective randomised open-label comparison of danaparoid with dextran 70 in the treatment of heparin-induced thrombocytopenia with thrombosis. A clinical outcome study
    • Chong B.H., Gallus A.S., Cade J.F., Magnani H., Manoharan A., Oldmeadow M.et al. Prospective randomised open-label comparison of danaparoid with dextran 70 in the treatment of heparin-induced thrombocytopenia with thrombosis. A clinical outcome study. Thromb. Haemost. 86:2001;1170-1175.
    • (2001) Thromb. Haemost. , vol.86 , pp. 1170-1175
    • Chong, B.H.1    Gallus, A.S.2    Cade, J.F.3    Magnani, H.4    Manoharan, A.5    Oldmeadow, M.6
  • 23
    • 0001571413 scopus 로고    scopus 로고
    • Argatroban therapy in heparin-induced thrombocytopenia
    • T.E. Warkentin, & A. Greinacher. New York: Marcel Dekker
    • Lewis B.E., Hursting M.J. Argatroban therapy in heparin-induced thrombocytopenia. Warkentin T.E., Greinacher A. Heparin-induced thrombocytopenia. 2nd ed. 2001;381-407 Marcel Dekker, New York.
    • (2001) Heparin-induced Thrombocytopenia 2nd Ed. , pp. 381-407
    • Lewis, B.E.1    Hursting, M.J.2
  • 24
    • 0000885094 scopus 로고    scopus 로고
    • Recombinant hirudin for the treatment of heparin-induced thrombocytopenia
    • T.E. Warkentin, & A. Greinacher. New York: Marcel Dekker
    • Greinacher A. Recombinant hirudin for the treatment of heparin-induced thrombocytopenia. Warkentin T.E., Greinacher A. Heparin-induced thrombocytopenia. 2nd ed. 2001;349-380 Marcel Dekker, New York.
    • (2001) Heparin-induced Thrombocytopenia 2nd Ed. , pp. 349-380
    • Greinacher, A.1
  • 25
    • 0027959329 scopus 로고
    • Effects of the synthetic thrombin inhibitor argatroban on fibrin- or clot-incorporated thrombin: Comparison with heparin and recombinant hirudin
    • Berry C.N., Girardot C., Lecoffre C., Lunven C. Effects of the synthetic thrombin inhibitor argatroban on fibrin- or clot-incorporated thrombin: comparison with heparin and recombinant hirudin. Thromb. Haemost. 72:1994;381-386.
    • (1994) Thromb. Haemost. , vol.72 , pp. 381-386
    • Berry, C.N.1    Girardot, C.2    Lecoffre, C.3    Lunven, C.4
  • 26
    • 0035082406 scopus 로고    scopus 로고
    • Interpreting the International Normalized Ratio (INR) in individuals receiving argatroban and warfarin
    • Sheth S.B., DiCicco R.A., Hursting M.J., Montague T., Jorkasky D.K. Interpreting the International Normalized Ratio (INR) in individuals receiving argatroban and warfarin. Thromb. Haemost. 85:2001;435-440.
    • (2001) Thromb. Haemost. , vol.85 , pp. 435-440
    • Sheth, S.B.1    DiCicco, R.A.2    Hursting, M.J.3    Montague, T.4    Jorkasky, D.K.5
  • 27
    • 79960971546 scopus 로고    scopus 로고
    • Transition from argatroban to warfarin in patients with heparin-induced thrombocytopenia
    • [abstract]
    • Hiatt B.K., Macfarlane D.E., Hursting M.J. Transition from argatroban to warfarin in patients with heparin-induced thrombocytopenia. [abstract] Blood. 98:2001;91b.
    • (2001) Blood , vol.98
    • Hiatt, B.K.1    Macfarlane, D.E.2    Hursting, M.J.3
  • 28
    • 0034307370 scopus 로고    scopus 로고
    • Antihirudin antibodies in patients with heparin-induced thrombocytopenia treated with lepirudin: Incidence, effects on aPTT, and clinical relevance
    • Eichler P., Friesen H.J., Lubenow N., Jaeger B., Greinacher A. Antihirudin antibodies in patients with heparin-induced thrombocytopenia treated with lepirudin: incidence, effects on aPTT, and clinical relevance. Blood. 96:2000;2373-2378.
    • (2000) Blood , vol.96 , pp. 2373-2378
    • Eichler, P.1    Friesen, H.J.2    Lubenow, N.3    Jaeger, B.4    Greinacher, A.5
  • 29
    • 0036507937 scopus 로고    scopus 로고
    • Argatroban therapy does not generate antibodies that alter its anticoagulant activity in patients with heparin-induced thrombocytopenia
    • Walenga J.M., Ahmad S., Hoppensteadt D., Iqbal O., Hursting M.J., Lewis B.E. Argatroban therapy does not generate antibodies that alter its anticoagulant activity in patients with heparin-induced thrombocytopenia. Thromb. Res. 105:2002;401-405.
    • (2002) Thromb. Res. , vol.105 , pp. 401-405
    • Walenga, J.M.1    Ahmad, S.2    Hoppensteadt, D.3    Iqbal, O.4    Hursting, M.J.5    Lewis, B.E.6
  • 30
    • 0043262078 scopus 로고    scopus 로고
    • Anaphylactic and anaphylactoid reactions associated with lepirudin in patients with heparin-induced thrombocytopenia abstract
    • Greinacher A., Lubenow N., Eichler P. Anaphylactic and anaphylactoid reactions associated with lepirudin in patients with heparin-induced thrombocytopenia abstract. J. Thromb. Hemost. 1(Suppl. 1):2003;OC022.
    • (2003) J. Thromb. Hemost. , vol.1 , Issue.SUPPL. 1 , pp. 022
    • Greinacher, A.1    Lubenow, N.2    Eichler, P.3
  • 32
    • 0032873201 scopus 로고    scopus 로고
    • Multicentric warfarin-induced skin necrosis complicating heparin-induced thrombocytopenia
    • Warkentin T.E., Sikov W.M., Lillicrap D.P. Multicentric warfarin-induced skin necrosis complicating heparin-induced thrombocytopenia. Am. J. Hematol. 62:1999;44-48.
    • (1999) Am. J. Hematol. , vol.62 , pp. 44-48
    • Warkentin, T.E.1    Sikov, W.M.2    Lillicrap, D.P.3
  • 35
    • 0035899952 scopus 로고    scopus 로고
    • Venous limb gangrene during warfarin treatment of cancer-associated deep venous thrombosis
    • Warkentin T.E. Venous limb gangrene during warfarin treatment of cancer-associated deep venous thrombosis. Ann. Intern. Med. 135:2001;589-593.
    • (2001) Ann. Intern. Med. , vol.135 , pp. 589-593
    • Warkentin, T.E.1
  • 37
    • 0032724209 scopus 로고    scopus 로고
    • Safety of warfarin anticoagulation in patients with heparin-induced thrombocytopenia
    • Wallis D.E., Quintos R., Wehrmacher W., Messmore H. Safety of warfarin anticoagulation in patients with heparin-induced thrombocytopenia. Chest. 116:1999;1333-1338.
    • (1999) Chest , vol.116 , pp. 1333-1338
    • Wallis, D.E.1    Quintos, R.2    Wehrmacher, W.3    Messmore, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.