Dose-response study of recombinant factor VIIa/tissue factor inhibitor recombinant nematode anticoagulant protein c2 in prevention of postoperative venous thromboembolism in patients undergoing total knee replacement

Circulation

Volumn 104, Issue 1, 2001, Pages 74-78

  Lee, Agnes ^a   Agnelli, Giancarlo ^b   Büller, Harry ^c   Ginsberg, Jeffrey ^a   Heit, John ^d   Rote, William ^e   Vlasuk, George ^e   Costantini, Lorrie ^a   Julian, Jim ^a   Comp, Philip ^f   Van Der Meer, Jan ^g   Piovella, Franco ^h   Raskob, Gary ^f   Gent, Michael ^a,i  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF PERUGIA   (Italy)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d MAYO CLINIC   (United States)

^e Dendreon   (United States)

^f UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^g UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^h UNIVERSITY OF PAVIA   (Italy)

ⁱ HAMILTON HEALTH SCIENCES   (Canada)

Author keywords

Anticoagulants; Knee; Replacement; Thrombosis

Indexed keywords

ANTICOAGULANT AGENT; RECOMBINANT BLOOD CLOTTING FACTOR 7A; RECOMBINANT FACTOR 7A INHIBITOR; RECOMBINANT NEMATODE ANTICOAGULANT PROTEIN C2; RECOMBINANT TISSUE FACTOR INHIBITOR; TISSUE FACTOR PATHWAY INHIBITOR; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; DEEP VEIN THROMBOSIS; DRUG EFFICACY; DRUG SAFETY; HUMAN; MAJOR CLINICAL STUDY; MULTICENTER STUDY; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; THROMBOEMBOLISM; TOTAL KNEE REPLACEMENT; VEIN THROMBOSIS;

EID: 0035800075     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/hc2601.091386     Document Type: Article

References (12)

1. Prevention of venous thromboembolism
2. Efficacy and safety of low molecular weight heparin (ardeparin sodium) compared to warfarin for the prevention of venous thromboembolism after total knee replacement surgery: A double-blind, dose-ranging study
3. Prevention of venous thromboembolism after knee arthroplasty: A randomized, double-blind trial comparing enoxaparin with warfarin
4. Anticoagulant repertoire of the hookworm Ancylostoma caninum
5. Role of zymogen and activated factor X as scaffolds for the inhibition of the blood coagulation factor VIIa-tissue factor complex by recombinant nematode anticoagulant protein c2
6. Low-molecular-weight heparin prophylaxis using dalteparin in close proximity to surgery vs warfarin in hip arthroplasty patients
7. Thromboplastin activity of blood monocytes after total hip replacement
8. Roentgen diagnosis of venous thrombosis of the leg
9. Pulmonary angiography, ventilation lung scanning, and venography for clinically suspected pulmonary embolism with abnormal perfusion lung scan
10. Use of Hirulog in the prevention of venous thrombosis after major hip or knee surgery
11. Ability of recombinant factor VIIa to generate thrombin during inhibition of tissue factor in human subjects