Apoptosis induced by penta-acetyl geniposide in C6 glioma cells is associated with JNK activation and Fas ligand induction

Toxicology and Applied Pharmacology

Volumn 202, Issue 2, 2005, Pages 172-179

  Peng, Chiung Huei ^a,b   Tseng, Tsui Hwa ^a   Huang, Chien Ning ^c   Hsu, Shu Ping ^a   Wang, Chau Jong ^a  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b HUNGKUANG UNIVERSITY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Apoptosis; c Jun; caspase 3; caspase 8; Fas; Fas L; JNK; Penta acetyl geniposide; PKC

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CASPASE 3; CASPASE 8; FAS LIGAND; GENIPOSIDE; PENTAACETYLGENIPOSIDE; ROTTLERIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOWNSTREAM PROCESSING; ENZYME ACTIVATION; GLIOMA CELL; NONHUMAN; PHOSPHORYLATION; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CASPASE 3; CASPASE 8; CASPASES; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; DRUGS, CHINESE HERBAL; FAS LIGAND PROTEIN; GARDENIA; GLIOMA; GLUCOSIDES; IRIDOIDS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MEMBRANE GLYCOPROTEINS; MITOCHONDRIA; PHOSPHORYLATION; PROTEIN KINASE C; PYRANS; RATS; SIGNAL TRANSDUCTION; TAIWAN; UP-REGULATION;

STAPHYLOCOCCUS PHAGE 3A;

EID: 11144265656     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.taap.2004.06.016     Document Type: Article

References (53)

1. V. Adler, C.C. Franklin, and A.S. Kraft Phorbol esters stimulate the phosphorylation of c-Jun but not v-Jun; regulation by the N-terminal delta domain Proc. Natl. Acad. Sci. U. S. A. 89 1992 5341 5345
2. M.A. Bae, and B.J. Song Critical role of c-Jun N-terminal protein kinase activation in troglitazone-induced apoptosis of human HepG2 hepatoma cells Mol. Pharmacol. 63 2003 401 408
3. M. Bando, M. Hasegawa, Y. Tsuboi, Y. Miyake, M. Shiina, M. Ito, H. Handa, K. Nagai, and T. Kataoka The mycotoxin penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8 in death-inducing signaling complex J. Biol. Chem. 278 2003 5786 5793
4. R.K. Barr, and M.A. Bogoyevitch The c-Jun N-terminal protein kinase family of mitogen-activated protein kinase (JNK MAPKs) Int. J. Biochem. Cell Biol. 33 2001 1047 1063
5. P. Benda, J. Lightbody, G. Sato, L. Levine, and W. Sweet Differentiated rat glial cell strain in tissue culture Science 161 1968 370 371
6. A. Cataldi, S. Miscia, L. Centurione, M. Rapino, D. Bosco, G. Grifone, V.D. Valerio, F. Garaci, and R. Rana Role of nuclear PKC delta in mediating caspase-3-upregulation in Jurkat T leukemic cells exposed to ionizing radiation J. Cell. Biochem. 86 2002 553 560
7. Y.C. Chang, T.H. Tseng, M.J. Lee, J.D. Hsu, and C.J. Wang Induction of apoptosis by penta-acetyl geniposide in rat C6 glioma cells Chem.-Biol. Interact. 141 2002 243 257
8. Y.C. Chang, F.P. Chou, H.P. Huang, J.D. Hsu, and C.J. Wang Inhibition of cell cycle progression by penta-acetyl geniposide in rat C6 glioma cells Toxicol. Appl. Pharmacol. 198 2004 11 20
9. D. Chauhan, G. Li, T. Hideshima, K. Podar, C. Mitsiades, N. Mitsiades, N. Munshi, S. Kharbanda, and K.C. Anderson JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells J. Biol. Chem. 278 2003 17593 17596
10. Y. Chen, Q. Wu, S.Y. Song, and W.J. Su Activation of JNK by TPA promotes apoptosis via PKC pathway in gastric cancer cells World J. Gastroenterol. 8 2002 1014 1018
11. R.J. Davis Signal transduction by the JNK group of MAP kinases Cell 103 2000 239 252
12. E. De Smaele, F. Zazzeroni, S. Papa, D.U. Nguyen, R. Jin, J. Jones, R. Cong, and G. Franzoso Induction of gadd45beta by NF-κB downregulates proapoptotic JNK signaling Nature 414 2001 308 313
13. Y. Deng, Y. Lin, and X. Wu TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO Genes Dev. 16 2002 33 45
14. I. Ferrer, and A.M. Planas Signaling of cell death and cell survival following focal cerebral ischemia: life and death struggle in the penumbra J. Neuropathol. Exp. Neurol. 62 2003 329 339
15. M. Fukunaga, M. Oka, M. Ichihashi, T. Yamamoto, H. Matsuzaki, and U. Kikkawa UV-induced tyrosine phosphorylation of PKC delta and promotion of apoptosis in the HaCaT cell line Biochem. Biophys. Res. Commun. 289 2001 573 579
16. J.P. Godbout, J. Pesavento, M.E. Hartman, S.R. Manson, and G.G. Freund Methylglyoxal enhances cisplatin-induced cytotoxicity by activating protein kinase Cδ J. Biol. Chem. 277 2002 2554 2561
17. Y.L. Guo, B. Kang, and J.R. Williamson Resistance to TNF-α cytotoxicity can be achieved through different signaling pathways in rat mesangial cells Am. J. Physiol. 276 1999 C435 C441
18. T. Hara, H. Namba, T.T. Yang, Y. Nagayama, S. Fukata, K. Kuma, N. Ishikawa, K. Ito, and S. Yamashita Ionizing radiation activates c-Jun NH2-terminal kinase (JNK/SAPK) via a PKC-dependent pathway in human thyroid cells Biochem. Biophys. Res. Commun. 244 1998 41 44
19. M. Hibi, A. Lin, T. Smeal, A. Minden, and M. Karin Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain Genes Dev. 7 1993 2135 2148
20. D. Javelaud, and F. Besancon NF-κB activation results in rapid inactivation of JNK in TNF alpha-treated Ewing sarcoma cells: a mechanism for the antiapoptotic effect of NF-κB Oncogene 20 2001 4365 4372
21. J.J. Kang, H.W. Wang, T.Y. Liu, Y.C. Chen, and T.H. Ueng Modulation of cytochrome P-450-dependent monooxygenases, glutathione and glutathione S-transferase in rat liver by geniposide from Gardenia jasminoides Food Chem. Toxicol. 35 1997 957 965
22. H.J. Kang, Y. Soh, M.S. Kim, E.J. Lee, Y.J. Surh, H.R. Kim, S.H. Kim, and A. Moon Roles of JNK-1 and p38 in selective induction of apoptosis by capsaicin in ras-transformed human breast epithelial cells Int. J. Cancer 103 2003 475 482
23. J. Kim, and M.R. Freeman JNK/SAPK mediates doxorubicin-induced differentiation and apoptosis in MCF-7 breast cancer cells Breast Cancer Res. Treat. 79 2003 321 328
24. S.Y. Lee, A. Reichlin, A. Santana, K.A. Sokol, M.C. Nussenzweig, and Y. Choi TRAF2 is essential for JNK but not NF-κB activation and regulates lymphocyte proliferation and survival Immunity 7 1997 703 713
25. K. Lei, and R.J. Davis JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis Proc. Natl. Acad. Sci. U. S. A. 100 2003 2432 2437
26. H. Le-Niculescu, E. Bonfoco, Y. Kasuya, F.X. Claret, D.R. Green, and M. Karin Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death Mol. Cell. Biol. 19 1999 751 763
27. H. Li, H. Zhu, C.J. Xu, and J. Yuan Cleavage of BID by caspase 8 mediates the mitochondrial damage in Fas pathway of apoptosis Cell 94 1998 491 501
28. A. Lin Activation of the JNK signaling pathway: breaking the brake on apoptosis Bioessay 25 2002 17 24
29. Y.L. Lin, J.D. Hsu, F.P. Chou, M.J. Lee, S.J. Shiow, and C.J. Wang Suppressive effect of penta-acetyl geniposide on the development of γ-glutamyl transpeptidase foci-induced by aflatoxin B1 in rats Chem.-Biol. Interact. 128 2000 115 126
30. A. Mansouri, L.D. Ridgway, A.L. Korapati, Q. Zhang, L. Tian, Y. Wang, Z.H. Siddik, G.B. Mills, and F.X. Claret Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells J. Biol. Chem. 278 2003 19245 19256
31. S.S. Molton, D.E. Todd, and S.J. Cook Selective activation of the c-Jun N-terminal kinase (JNK) pathway fails to elicit Bax activation or apoptosis unless the phosphoinositide 3′-kinase (PI3K) pathway is inhibited Oncogene 22 2003 4690 4701
32. G. Natoli, A. Costanzo, A. Ianni, D.J. Templeton, J.R. Woodgett, C. Balsano, and M. Levrero Activation of SAPK/JNK by TNF receptor 1 through a non-cytotoxic TRAF2-dependent pathway Science 275 1997 200 203
33. C.H. Peng, J.Y. Liu, Y.H. Hsieh, C.N. Huang, S.P. Hsu, and C.J. Wang Penta-acetyl geniposide-induced C6 glioma cell apoptosis was associated with the activation of protein kinase C-delta Chem.-Biol. Interact. 147 2004 287 296
34. G.V. Putcha, S. Le, S. Frank, C.G. Besirli, K. Clark, B. Chu, S. Alix, R.J. Youle, A. LaMarche, A.C. Maroney, and E.M. Johonson Jr. JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis Neuron 38 2003 899 914
35. M. Puviani, A. Marconi, E. Cozzani, and C. Pincelli Fas ligand in pemphigus sera induces keratinocyte apoptosis through the activation of caspase-8 J. Invest. Dermatol. 120 2003 164 167
36. S.L. Shankar, S. Mani, K.N. O'Guin, E.R. Kandimalla, S. Agrawal, and B. Shafit-Zagardo Survivin inhibition induces human neural tumor cell death through caspase-independent and -dependent pathways J. Neurochem. 79 2001 426 436
37. D. Siegmund, D. Mauri, N. Peters, P. Juo, M. Thome, M. Reichwein, J. Blenis, P. Scheurich, J. Tschopp, and H. Wajant Fas-associated death domain protein (FADD) and caspase-8 mediate up-regulation of c-Fos by Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) via a FLICE inhibitory protein (FLIP)-regulated pathway J. Biol. Chem. 276 2001 32585 32590
38. W.E. Smith, A.V. Kane, S.T. Campbell, D.W. Acheson, B.H. Cochran, and C.M. Thorpe Shiga toxin 1 triggers a ribotoxic stress response leading to p38 and JNK activation and induction of apoptosis in intestinal epithelial cells Infect. Immun. 71 2003 1497 1504
39. M. Tafani, N.O. Karpinich, K.A. Hurster, J.G. Pastorino, T. Schneider, M.A. Russo, and J.L. Farber Cytochrome c release upon Fas receptor activation depends on translocation of full-length bid and the induction of the mitochondrial permeability transition J. Biol. Chem. 277 2002 10073 10082
40. G. Tang, Y. Minemo, B. Dibling, N.H. Purcell, Z. Li, M. Karin, and A. Lin Inhibition of JNK activation through NF-κB target genes Nature 414 2001 313 317
41. M.T. Tomicic, C. Friedrichs, M. Christmann, P. Wutzler, R. Thust, and B. Kaina Apoptosis induced by (E)-5-(2-bromovinyl)-2′-deoxyuridine in varicella zoster virus thymidine kinase-expressing cells is driven by activation of c-Jun/activator protein-1 and Fas ligand/caspase-8 Mol. Pharmacol. 63 2003 439 449
42. T.H. Tseng, C.Y. Chu, and C.J. Wang Inhibition of penta-acetyl geniposide on AFB1-induced genotoxicity in C3H10T1/2 cells Cancer Lett. 62 1992 233 242
43. T.H. Tseng, C.Y. Chu, and C.J. Wang Comparison of geniposide and its acetylated derivative for the inhibition of aflatoxin B1-induced DNA repair synthesis in rat primary hepatocyte Oncol. Rep. 1 1994 161 168
44. A. Tyagi, R. Agarwal, and C. Agarwal Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU145 cells: possible role in antiproliferation and apoptosis Oncogene 22 2003 1302 1316
45. A.M. Verhagen, and D.L. Vaux Cell death regulation by the mammalian IAP antagonist Diablo/Smac Apoptosis 7 2002 163 166
46. D. Vucic, K. Deshayes, H. Ackerly, M.T. Pisabarro, S. Kadkhodayan, W.J. Fairbrother, and V.M. Dixit SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP) J. Biol. Chem. 277 2002 12275 12279
47. C.J. Wang, S.W. Wang, and J.K. Lin Suppressive effect of geniposide on hepatoxicity and hepatic DNA binding of aflatoxin B1 in rats Cancer Lett. 60 1991 95 102
48. C.J. Wang, T.H. Tseng, and J.K. Lin Penta-acetyl geniposide: isolation, identification and primary effect on C6 glioma cell in vitro Anticancer Res. 12 1992 911 916
49. C.J. Wang, C.Y. Chu, T.H. Tseng, and J.K. Lin Penta-acetyl geneposide inhibits the growth and development of C-6 glioma cells in rats Cancer Lett. 70 1993 113 118
50. G. Werlen, E. Jacinto, Y. Xia, and M. Karin Calcineurin preferentially synergizes with PKC-theta to activate JNK and IL-2 promoter in T lymphocytes EMBO J. 17 1998 3101 3111
51. H. Yamaguchi, K. Bhalla, and H.G. Wang Bax plays a pivotal role in thapsigargin-induced apoptosis of human colon cancer HCT116 cells by controlling Smac/Diablo and Omi/HtrA2 release from mitochondria Cancer Res. 63 2003 1483 1489
52. X.M. Yin Bid, a critical mediator for apoptosis induced by the activation of Fas/TNF-R1 death receptors in hepatocytes J. Mol. Med. 78 2000 203 211
53. X.M. Zhang, E. Moilanen, A. Lahti, M. Hamalainen, M.A. Giembycz, P.J. Barnes, M.A. Lindsay, and H. Kankaanranta Regulation of eosinophil apoptosis by nitric oxide: role of c-Jun-N terminal kinase and signal transduced and activator of transcription 5 J. Allergy Clin. Immunol. 112 2003 93 101