Apoptosis induced by (E)-5-(2-bromovinyl)-2′-deoxyuridine in varicella zoster virus thymidine kinase-expressing cells is driven by activation of c-Jun/activator protein-1 and Fas ligand/caspase-8

Molecular Pharmacology

Volumn 63, Issue 2, 2003, Pages 439-449

  Tomicic, Maja T ^a   Friedrichs, Claudia ^b   Christmann, Markus ^a   Wutzler, Peter ^b   Thust, Rudolf ^b   Kaina, Bernd ^a,c  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^c Institute of Toxicology   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

5 (2 BROMOVINYL) 2' DEOXYURIDINE; ANTIVIRUS AGENT; BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; CASPASE 8; CASPASE INHIBITOR; FAS ANTIGEN; FAS LIGAND; GANCICLOVIR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; STRESS ACTIVATED PROTEIN KINASE; THYMIDINE KINASE; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL KILLING; CHO CELL; COLONY FORMING UNIT; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME INHIBITION; GENETIC TRANSFECTION; HERPES SIMPLEX VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; VARICELLA ZOSTER VIRUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIVIRAL AGENTS; APOPTOSIS; BROMODEOXYURIDINE; CARRIER PROTEINS; CASPASE 8; CASPASE 9; CASPASES; CELL CYCLE; CHO CELLS; CRICETINAE; DNA; FAS LIGAND PROTEIN; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; GENOME; HERPESVIRUS 3, HUMAN; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MEMBRANE GLYCOPROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; NECROSIS; SIMPLEXVIRUS; THYMIDINE KINASE; THYMIDYLATE SYNTHASE; TRANSCRIPTION FACTOR AP-1; TRANSFECTION;

EID: 0037310208     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.63.2.439     Document Type: Article

References (43)

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