-
1
-
-
0036244309
-
Medical management of breast cancer: Today and tomorrow
-
Chew HK: Medical management of breast cancer: today and tomorrow. Cancer Biother Radio 17: 137-149, 2002
-
(2002)
Cancer Biother Radio
, vol.17
, pp. 137-149
-
-
Chew, H.K.1
-
2
-
-
0033959520
-
Cancer statistics, 2000
-
Greenlee RT, Murray T, Bolden S, Wingo PA: Cancer statistics, 2000. CA-Cancer J Clin 50: 7-33, 2000
-
(2000)
CA-Cancer J Clin
, vol.50
, pp. 7-33
-
-
Greenlee, R.T.1
Murray, T.2
Bolden, S.3
Wingo, P.A.4
-
3
-
-
0033064653
-
Topoisomerase poisoning activity of novel disaccharide anthracyclines
-
Guano F, Pourquier P, Tinelli S, Binaschi M, Bigioni M, Animati F, Manzini S, Zunino F, Kohlhagen G, Pommier Y, Capranico G: Topoisomerase poisoning activity of novel disaccharide anthracyclines. Mol Pharmacol 56: 77-84, 1999
-
(1999)
Mol Pharmacol
, vol.56
, pp. 77-84
-
-
Guano, F.1
Pourquier, P.2
Tinelli, S.3
Binaschi, M.4
Bigioni, M.5
Animati, F.6
Manzini, S.7
Zunino, F.8
Kohlhagen, G.9
Pommier, Y.10
Capranico, G.11
-
4
-
-
0031987938
-
Anthracycline-derived chemotherapeutics in apoptosis and free radical cytotoxicity
-
Muller I, Niethammer D, Bruchelt G: Anthracycline-derived chemotherapeutics in apoptosis and free radical cytotoxicity (Review). Int J Mol Med 1: 491-494, 1998
-
(1998)
Int J Mol Med
, vol.1
, pp. 491-494
-
-
Muller, I.1
Niethammer, D.2
Bruchelt, G.3
-
5
-
-
0034631974
-
Doxorubicin treatment activates a Z-VAD-sensitive caspase, which causes deltapsim loss, caspase-9 activity, and apoptosis in Jurkat cells
-
Gamen S, Anel A, Perez-Galan P, Lasierra P, Johnson D, Pineiro A, Naval J: Doxorubicin treatment activates a Z-VAD-sensitive caspase, which causes deltapsim loss, caspase-9 activity, and apoptosis in Jurkat cells. Exp Cell Res 258: 223-235, 2000
-
(2000)
Exp Cell Res
, vol.258
, pp. 223-235
-
-
Gamen, S.1
Anel, A.2
Perez-Galan, P.3
Lasierra, P.4
Johnson, D.5
Pineiro, A.6
Naval, J.7
-
6
-
-
0034145121
-
Comparison of effects of doxorubicin and radiation on p53-dependent apoptosis in vivo
-
Hayakawa K, Hasegawa M, Kawashima M, Nakamura Y, Matsuura M, Toda H, Mitsuhashi N, Niibe H: Comparison of effects of doxorubicin and radiation on p53-dependent apoptosis in vivo. Oncol Rep 7: 267-270, 2000
-
(2000)
Oncol Rep
, vol.7
, pp. 267-270
-
-
Hayakawa, K.1
Hasegawa, M.2
Kawashima, M.3
Nakamura, Y.4
Matsuura, M.5
Toda, H.6
Mitsuhashi, N.7
Niibe, H.8
-
7
-
-
0033775972
-
Involvement of cyclin-dependent kinases in doxorubicin-induced apoptosis in human tumor cells
-
Lu Y, Tatsuka M, Takebe H, Yagi T: Involvement of cyclin-dependent kinases in doxorubicin-induced apoptosis in human tumor cells. Mol Carcinogen 29: 1-7, 2000
-
(2000)
Mol Carcinogen
, vol.29
, pp. 1-7
-
-
Lu, Y.1
Tatsuka, M.2
Takebe, H.3
Yagi, T.4
-
8
-
-
0027237540
-
Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumour cells
-
Skladanowski A, Konopa J: Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumour cells. Biochem Pharmacol 46: 375-382, 1993
-
(1993)
Biochem Pharmacol
, vol.46
, pp. 375-382
-
-
Skladanowski, A.1
Konopa, J.2
-
9
-
-
0029911278
-
Apoptosis of hair follicle cells during doxorubicin-induced alopecia in rats
-
Cece R, Cazzaniga S, Morelli D, Sfondrini L, Bignotto M, Menard S, Colnaghi MI, Balsari A: Apoptosis of hair follicle cells during doxorubicin-induced alopecia in rats. Lab Invest 75: 601-609, 1996
-
(1996)
Lab Invest
, vol.75
, pp. 601-609
-
-
Cece, R.1
Cazzaniga, S.2
Morelli, D.3
Sfondrini, L.4
Bignotto, M.5
Menard, S.6
Colnaghi, M.I.7
Balsari, A.8
-
10
-
-
0029925537
-
Upregulation of cytokeratins 8 and 18 in human breast cancer T47D cells is retinoid-specific and retinoic acid receptor-dependent
-
Jing Y, Zhang J, Waxman S, Mira-y-Lopez R: Upregulation of cytokeratins 8 and 18 in human breast cancer T47D cells is retinoid-specific and retinoic acid receptor-dependent. Differentiation 60: 109-117, 1996
-
(1996)
Differentiation
, vol.60
, pp. 109-117
-
-
Jing, Y.1
Zhang, J.2
Waxman, S.3
Mira-Y-Lopez, R.4
-
11
-
-
0030803635
-
Overexpression of metallothionein in the heart of transgenic mice suppresses doxorubicin cardiotoxicity
-
Kang YJ, Chen Y, Yu A, Voss-McCowan M, Epstein PN: Overexpression of metallothionein in the heart of transgenic mice suppresses doxorubicin cardiotoxicity. J Clin Invest 100: 1501-1506, 1997
-
(1997)
J Clin Invest
, vol.100
, pp. 1501-1506
-
-
Kang, Y.J.1
Chen, Y.2
Yu, A.3
Voss-McCowan, M.4
Epstein, P.N.5
-
12
-
-
0032955692
-
Metallothionein inhibits ischemia-reperfusion injury in mouse heart
-
Kang YJ, Li G, Saari JT: Metallothionein inhibits ischemia-reperfusion injury in mouse heart. Am J Physiol 276: H993-H997, 1999
-
(1999)
Am J Physiol
, vol.276
-
-
Kang, Y.J.1
Li, G.2
Saari, J.T.3
-
13
-
-
0032799673
-
Enhanced inhibition of experimental metastasis by the combination chemotherapy of Cu-Zn SOD and adriamycin
-
Kogawa K, Muramatsu H, Tanaka M, Nishihori Y, Hagiwara S, Kuribayashi K, Nakamura K, Koike K, Sakamaki S, Niitsu Y: Enhanced inhibition of experimental metastasis by the combination chemotherapy of Cu-Zn SOD and adriamycin. Clin Exp Metastas 17: 239-244, 1999
-
(1999)
Clin Exp Metastas
, vol.17
, pp. 239-244
-
-
Kogawa, K.1
Muramatsu, H.2
Tanaka, M.3
Nishihori, Y.4
Hagiwara, S.5
Kuribayashi, K.6
Nakamura, K.7
Koike, K.8
Sakamaki, S.9
Niitsu, Y.10
-
14
-
-
0022115865
-
The 1985 Walter Hubert lecture. Malignant cell differentiation as a potential therapeutic approach
-
Sartorelli AC: The 1985 Walter Hubert lecture. Malignant cell differentiation as a potential therapeutic approach. Brit J Cancer 52: 293-302, 1985
-
(1985)
Brit J Cancer
, vol.52
, pp. 293-302
-
-
Sartorelli, A.C.1
-
15
-
-
0031035671
-
Differentiation, differentiation/gene therapy and cancer
-
Scott RE: Differentiation, differentiation/gene therapy and cancer. Pharmacol Therapeut 73: 51-65, 1997
-
(1997)
Pharmacol Therapeut
, vol.73
, pp. 51-65
-
-
Scott, R.E.1
-
16
-
-
0034816040
-
Differentiation therapy of human cancer: Basic science and clinical applications
-
Leszczyniecka M, Roberts T, Dent P, Grant S, Fisher PB: Differentiation therapy of human cancer: basic science and clinical applications. Pharmacol Therapeut 90: 105-156, 2001
-
(2001)
Pharmacol Therapeut
, vol.90
, pp. 105-156
-
-
Leszczyniecka, M.1
Roberts, T.2
Dent, P.3
Grant, S.4
Fisher, P.B.5
-
17
-
-
0025173016
-
Effects of differentiation-inducing agents on maturation of human MCF-7 breast cancer cells
-
Guilbaud NF, Gas N, Dupont MA, Valette A: Effects of differentiation-inducing agents on maturation of human MCF-7 breast cancer cells. J Cell Physiol 145: 162-172, 1990
-
(1990)
J Cell Physiol
, vol.145
, pp. 162-172
-
-
Guilbaud, N.F.1
Gas, N.2
Dupont, M.A.3
Valette, A.4
-
18
-
-
0025651283
-
Differentiation of cultured human breast cancer cells (AU-565 and MCF-7) associated with loss of cell surface HER-2/neu antigen
-
Bacus SS, Kiguchi K, Chin D, King CR, Huberman E: Differentiation of cultured human breast cancer cells (AU-565 and MCF-7) associated with loss of cell surface HER-2/neu antigen. Mol Carcinogen 3: 350-362, 1990
-
(1990)
Mol Carcinogen
, vol.3
, pp. 350-362
-
-
Bacus, S.S.1
Kiguchi, K.2
Chin, D.3
King, C.R.4
Huberman, E.5
-
19
-
-
0028129285
-
Induction of differentiation and growth arrest associated with nascent (nonoligosomal) DNA fragmentation and reduced c-myc expression in MCF-7 human breast tumor cells after continuous exposure to a sublethal concentration of doxorubicin
-
Fornari Jr FA, Jarvis WD, Grant S, Orr MS, Randolph JK, White FK, Mumaw VR, Lovings ET, Freeman RH, Gewirtz DA: Induction of differentiation and growth arrest associated with nascent (nonoligosomal) DNA fragmentation and reduced c-myc expression in MCF-7 human breast tumor cells after continuous exposure to a sublethal concentration of doxorubicin. Cell Growth Differ 5: 723-733, 1994
-
(1994)
Cell Growth Differ
, vol.5
, pp. 723-733
-
-
Fornari F.A., Jr.1
Jarvis, W.D.2
Grant, S.3
Orr, M.S.4
Randolph, J.K.5
White, F.K.6
Mumaw, V.R.7
Lovings, E.T.8
Freeman, R.H.9
Gewirtz, D.A.10
-
20
-
-
0031740852
-
Genistein induces maturation of cultured human breast cancer cells and prevents tumor growth in nude mice
-
Constantinou AI, Krygier AE, Mehta RR: Genistein induces maturation of cultured human breast cancer cells and prevents tumor growth in nude mice. Am J Clin Nutr 68: 1426S-1430S, 1998
-
(1998)
Am J Clin Nutr
, vol.68
-
-
Constantinou, A.I.1
Krygier, A.E.2
Mehta, R.R.3
-
21
-
-
0032707473
-
Relaxin promotes differentiation of human breast cancer cells MCF-7 transplanted into nude mice
-
Bani D, Flagiello D, Poupon MF, Nistri S, Poirson-Bichat F, Bigazzi M, Bani Sacchi T: Relaxin promotes differentiation of human breast cancer cells MCF-7 transplanted into nude mice. Virchows Arch 435: 509-519, 1999
-
(1999)
Virchows Arch
, vol.435
, pp. 509-519
-
-
Bani, D.1
Flagiello, D.2
Poupon, M.F.3
Nistri, S.4
Poirson-Bichat, F.5
Bigazzi, M.6
Bani Sacchi, T.7
-
22
-
-
0033941122
-
A polyphenolic fraction from grape seeds causes irreversible growth inhibition of breast carcinoma MDA-MB468 cells by inhibiting mitogen-activated protein kinases activation and inducing G1 arrest and differentiation
-
Agarwal C, Sharma Y, Zhao J, Agarwal R: A polyphenolic fraction from grape seeds causes irreversible growth inhibition of breast carcinoma MDA-MB468 cells by inhibiting mitogen-activated protein kinases activation and inducing G1 arrest and differentiation. Clin Cancer Res 6: 2921-2930, 2000
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2921-2930
-
-
Agarwal, C.1
Sharma, Y.2
Zhao, J.3
Agarwal, R.4
-
23
-
-
0034634635
-
Rapid induction of histone hyperacetylation and cellular differentiation in human breast tumor cell lines following degradation of histone deacetylase-1
-
Zhou Q, Melkoumian ZK, Lucktong A, Moniwa M, Davie JR, Strobl JS: Rapid induction of histone hyperacetylation and cellular differentiation in human breast tumor cell lines following degradation of histone deacetylase-1. J Biol Chem 275: 35256-35263, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 35256-35263
-
-
Zhou, Q.1
Melkoumian, Z.K.2
Lucktong, A.3
Moniwa, M.4
Davie, J.R.5
Strobl, J.S.6
-
24
-
-
0035016664
-
Oncostatin M-induced growth inhibition and morphological changes of MDA-MB231 breast cancer cells are abolished by blocking the MEK/ERK signaling pathway
-
Li C, Ahlborn TE, Kraemer FB, Liu J: Oncostatin M-induced growth inhibition and morphological changes of MDA-MB231 breast cancer cells are abolished by blocking the MEK/ERK signaling pathway. Breast Cancer Res Tr 66: 111-121, 2001
-
(2001)
Breast Cancer Res Tr
, vol.66
, pp. 111-121
-
-
Li, C.1
Ahlborn, T.E.2
Kraemer, F.B.3
Liu, J.4
-
25
-
-
0035300564
-
Inhibition of heat shock protein 90 function by ansamycins causes the morphological and functional differentiation of breast cancer cells
-
Munster PN, Srethapakdi M, Moasser MM, Rosen N: Inhibition of heat shock protein 90 function by ansamycins causes the morphological and functional differentiation of breast cancer cells. Cancer Res 61: 2945-2952, 2001
-
(2001)
Cancer Res
, vol.61
, pp. 2945-2952
-
-
Munster, P.N.1
Srethapakdi, M.2
Moasser, M.M.3
Rosen, N.4
-
26
-
-
0035577768
-
The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces differentiation of human breast cancer cells
-
Munster PN, Troso-Sandoval T, Rosen N, Rifkind R, Marks PA, Richon VM: The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces differentiation of human breast cancer cells. Cancer Res 61: 8492-8497, 2001
-
(2001)
Cancer Res
, vol.61
, pp. 8492-8497
-
-
Munster, P.N.1
Troso-Sandoval, T.2
Rosen, N.3
Rifkind, R.4
Marks, P.A.5
Richon, V.M.6
-
27
-
-
0034799471
-
RRR-alpha-tocopheryl succinate induces MDA-MB-435 and MCF-7 human breast cancer cells to undergo differentiation
-
You H, Yu W, Sanders BG, Kline K: RRR-alpha-tocopheryl succinate induces MDA-MB-435 and MCF-7 human breast cancer cells to undergo differentiation. Cell Growth Differ 12: 471-480, 2001
-
(2001)
Cell Growth Differ
, vol.12
, pp. 471-480
-
-
You, H.1
Yu, W.2
Sanders, B.G.3
Kline, K.4
-
28
-
-
0031047962
-
Identification and characterization of a predominant isoform of human MKK3
-
Han J, Wang X, Jiang Y, Ulevitch RJ, Lin S: Identification and characterization of a predominant isoform of human MKK3. FEBS Lett 403: 19-22, 1997
-
(1997)
FEBS Lett
, vol.403
, pp. 19-22
-
-
Han, J.1
Wang, X.2
Jiang, Y.3
Ulevitch, R.J.4
Lin, S.5
-
29
-
-
0035105516
-
p38 mitogen-activated protein kinase-dependent activation of protein phosphatases 1 and 2A inhibits MEK1 and MEK2 activity and collagenase 1 (MMP-1) gene expression
-
Westermarck J, Li SP, Kallunki T, Han J, Kahari VM: p38 mitogen-activated protein kinase-dependent activation of protein phosphatases 1 and 2A inhibits MEK1 and MEK2 activity and collagenase 1 (MMP-1) gene expression. Mol Cell Biol 21: 2373-2383, 2001
-
(2001)
Mol Cell Biol
, vol.21
, pp. 2373-2383
-
-
Westermarck, J.1
Li, S.P.2
Kallunki, T.3
Han, J.4
Kahari, V.M.5
-
30
-
-
0036494197
-
Activation of the Erk mitogen-activated protein kinase pathway stimulates neuroendocrine differentiation in LNCaP cells independently of cell cycle withdrawal and STAT3 phosphorylation
-
Kim J, Adam RM, Freeman MR: Activation of the Erk mitogen-activated protein kinase pathway stimulates neuroendocrine differentiation in LNCaP cells independently of cell cycle withdrawal and STAT3 phosphorylation. Cancer Res 62: 1549-1554, 2002
-
(2002)
Cancer Res
, vol.62
, pp. 1549-1554
-
-
Kim, J.1
Adam, R.M.2
Freeman, M.R.3
-
31
-
-
0029753773
-
The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation
-
Chen YR, Wang X, Templeton D, Davis RJ, Tan TH: The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation. J Biol Chem 271: 31929-31936, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 31929-31936
-
-
Chen, Y.R.1
Wang, X.2
Templeton, D.3
Davis, R.J.4
Tan, T.H.5
-
32
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME: Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270: 1326-1331, 1995
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
33
-
-
0033564514
-
The phosphatidylinositol 3′-kinase pathway is a dominant growth factor-activated cell survival pathway in LNCaP human prostate carcinoma cells
-
Lin J, Adam RM, Santiestevan E, Freeman MR: The phosphatidylinositol 3′-kinase pathway is a dominant growth factor-activated cell survival pathway in LNCaP human prostate carcinoma cells. Cancer Res 59: 2891-2897, 1999
-
(1999)
Cancer Res
, vol.59
, pp. 2891-2897
-
-
Lin, J.1
Adam, R.M.2
Santiestevan, E.3
Freeman, M.R.4
-
34
-
-
0029805461
-
Elevated keratin 18 protein expression indicates a favorable prognosis in patients with breast cancer
-
Schaller G, Fuchs I, Pritze W, Ebert A, Herbst H, Pantel K, Weitzel H, Lengyel E: Elevated keratin 18 protein expression indicates a favorable prognosis in patients with breast cancer. Clin Cancer Res 2: 1879-1885, 1996
-
(1996)
Clin Cancer Res
, vol.2
, pp. 1879-1885
-
-
Schaller, G.1
Fuchs, I.2
Pritze, W.3
Ebert, A.4
Herbst, H.5
Pantel, K.6
Weitzel, H.7
Lengyel, E.8
-
35
-
-
0026709010
-
Tumor-inhibitory monoclonal antibodies to the HER-2/Neu receptor induce differentiation of human breast cancer cells
-
Bacus SS, Stancovski I, Huberman E, Chin D, Hurwitz E, Mills GB, Ullrich A, Sela M, Yarden Y: Tumor-inhibitory monoclonal antibodies to the HER-2/Neu receptor induce differentiation of human breast cancer cells. Cancer Res 52: 2580-2589, 1992
-
(1992)
Cancer Res
, vol.52
, pp. 2580-2589
-
-
Bacus, S.S.1
Stancovski, I.2
Huberman, E.3
Chin, D.4
Hurwitz, E.5
Mills, G.B.6
Ullrich, A.7
Sela, M.8
Yarden, Y.9
-
36
-
-
0027077838
-
Differentiation induction in human breast tumor cells by okadaic acid and related inhibitors of protein phosphatases 1 and 2A
-
Kiguchi K, Giometti C, Chubb CH, Fujiki H, Huberman E: Differentiation induction in human breast tumor cells by okadaic acid and related inhibitors of protein phosphatases 1 and 2A. Biochem Bioph Res Co 189: 1261-1267, 1992
-
(1992)
Biochem Bioph Res Co
, vol.189
, pp. 1261-1267
-
-
Kiguchi, K.1
Giometti, C.2
Chubb, C.H.3
Fujiki, H.4
Huberman, E.5
-
38
-
-
0029098225
-
Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents
-
Kharbanda S, Ren R, Pandey P, Shafman TD, Feller SM, Weichselbaum RR, Kufe DW: Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents. Nature 376: 785-788, 1995
-
(1995)
Nature
, vol.376
, pp. 785-788
-
-
Kharbanda, S.1
Ren, R.2
Pandey, P.3
Shafman, T.D.4
Feller, S.M.5
Weichselbaum, R.R.6
Kufe, D.W.7
-
39
-
-
0029417332
-
c-Abl activation regulates induction of the SEK1/stress-activated protein kinase pathway in the cellular response to 1-beta-D-arabinofuranosylcytosine
-
Kharbanda S, Pandey P, Ren R, Mayer B, Zon L, Kufe D: c-Abl activation regulates induction of the SEK1/stress-activated protein kinase pathway in the cellular response to 1-beta-D-arabinofuranosylcytosine. J Biol Chem 270: 30278-30281, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 30278-30281
-
-
Kharbanda, S.1
Pandey, P.2
Ren, R.3
Mayer, B.4
Zon, L.5
Kufe, D.6
-
40
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis RJ: Signal transduction by the JNK group of MAP kinases. Cell 103: 239-252, 2000
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
41
-
-
0035735754
-
Role of mitogen-activated protein kinases in the response of tumor cells to chemotherapy
-
Fan M, Chambers TC: Role of mitogen-activated protein kinases in the response of tumor cells to chemotherapy. Drug Resist Update 4: 253-267, 2001
-
(2001)
Drug Resist Update
, vol.4
, pp. 253-267
-
-
Fan, M.1
Chambers, T.C.2
-
42
-
-
0035839123
-
Activation of c-Jun amino-terminal kinase is required for retinoic acid-induced neural differentiation of P19 embryonal carcinoma cells
-
Wang H, Ikeda S, Kanno S, Guang LM, Ohnishi M, Sasaki M, Kobayashi T, Tamura S: Activation of c-Jun amino-terminal kinase is required for retinoic acid-induced neural differentiation of P19 embryonal carcinoma cells. FEBS Lett 503: 91-96, 2001
-
(2001)
FEBS Lett
, vol.503
, pp. 91-96
-
-
Wang, H.1
Ikeda, S.2
Kanno, S.3
Guang, L.M.4
Ohnishi, M.5
Sasaki, M.6
Kobayashi, T.7
Tamura, S.8
-
43
-
-
0034806431
-
Alterations of MAPK activities associated with intestinal cell differentiation
-
Ding Q, Wang Q, Evers BM: Alterations of MAPK activities associated with intestinal cell differentiation. Biochem Bioph Res Co 284: 282-288, 2001
-
(2001)
Biochem Bioph Res Co
, vol.284
, pp. 282-288
-
-
Ding, Q.1
Wang, Q.2
Evers, B.M.3
|