Activation of JNK by TPA promotes apoptosis via PKC pathway in gastric cancer cells

World Journal of Gastroenterology

Volumn 8, Issue 6, 2002, Pages 1014-1018

  Chen, Yan ^a   Wu, Qiao ^a   Song, Si Yang ^a   Su, Wen Jin ^a  

^a XIAMEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; WORTMANNIN;

ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL DEATH; CELL DIFFERENTIATION; CELL NUCLEUS; CELL PROLIFERATION; CHROMATIN CONDENSATION; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; FLUORESCENCE MICROSCOPE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NORTHERN BLOTTING; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA TRANSCRIPTION; SIGNAL TRANSDUCTION; STAINING; STOMACH CANCER; WESTERN BLOTTING;

EID: 0036900678     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v8.i6.1014     Document Type: Article

References (49)

1. Brunet A, Roux D, Lenormand P, Dowd S, Keyse S, Pouyssegur J. Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry. The EMBO J 1999; 18: 664-674
2. Feng DY, Zheng H, Tan Y, Cheng RX. Effect of phosphorylation of MAPK and Stat3 and expression of c-fos and c-jun proteins on hepatocarcinogenesis and their clinical significance. World J Gastroenterol 2001; 7: 33-36
3. Robinson MJ, Cobb MH. Mitogen-activated protein kinases pathways. Cur Opin Cell Biol 1997; 9: 180-186
4. Nishida E, Gotoh Y. The MAP kinase cascade is essential for diverse signal transduction pathways. Trends Biochem Science 1993; 18: 128-131
5. Mao H, Yuan AL, Zhao MF, Lai ZS, Zhang YL, Zhou DY. Effect of p38MAPK signal pathway on ultrastructural change of liver cancer cells induced by VEGF. Shi Jie Hua Ren Xiao Hua Za Zhi 2000; 8: 536-538
6. Fleischer F, Dabew R, Ke BG, Wagner ACC. Stress kinases inhibition modulates acute experimental pancreatitis. World J Gastroenterol 2001; 7: 259-265
7. Frost JA, Xu SC, Michele RH, Marcus S, Cobb MH. Actions of Rho family small G proteins and p21-activated protein kinases on mitogen-activated protein kinase family members. Mol Cel Biol 1996; 16: 3707-3713
8. Vrana JA, Grant S. Synergistic induction of apoptosis in human Leukemia cells (U937) exposed to bryostatin1 and the proteasome inhibitor lactacystin involves dysregulation of the PKC/MAPK cascade. Blood 2001; 97: 2105-2115
9. Cano E, Mahadevan LC. Parallel signal processing among mammalian MAPKs. Trends Biochem Science 1995; 20: 117-122
10. Hibi M, Lin A, Smeal T, Minden A, Karin M. Identification of an oncoprotein and UV-responsive protein kinase that binds and potentiates the c-jun activation domain. Genes Dev 1993; 7: 2135-2148
11. Ham J, Eiler A, Whitefield J, Neame SJ, Shah B. c-jun and the transcriptional control of neuronal apoptosis. Biochem Pharmacol 2000; 60: 1015-1021
12. Marais R, Wynne J, Treisman R. The SRF accessory protein Elk-1 contains a growth factor regulated transcriptional activation domain. Cell 1993; 73: 381-393
13. Gupta S, Campbell D, Derijard B, Daris RJ. Transcription factor ATF-2 regulation by the JNK signal transduction pathway. Science 1995; 267: 389-393
14. Xia Z, Dickens M, Raingeaud JJ, Daris RJ, Grenberg ME. Opposing effects of ERK and JNK, p38 MAPKs on apoptosis. Science 1995; 270: 1326-1331
15. Verheij M, Bose A, Lin XH, Yao B, Jarvis WD, Grant S, Birrer MJ, Szabo E, Zon LI, Kyriakis JM, Haimovitz FA, Fuks Z, Kolesnick RN. Requirement for ceramide-initiated SAPK/JNK signaling in stress-induced apoptosis. Nature 1996; 380: 75-79
16. Chen YR, Wang X, Templeton D, Davis RJ, Tan TH. The role of c-jun N-terminal kinase(JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation. J Biol Chem 1996; 271: 31929-31936
17. Osborn MT, Chambers TC. Role of the stress-activated/c-jun N-terminal protein kinase pathway in the cellular response to adriamycin and other chemotherapeutic drugs. J Biol Chem 1996; 271: 30950-30955
18. Khwaja A, Downward J. Lack of correlation between activation of Jun N-terminal kinase and induction of apoptosis after detachment of epithelial cells. J Cell Biol 1997; 139: 1017-1023
19. Liu ZG, Hsu H, Goeddel DV, Karin M. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κ B activation prevents cells death. Cell 1996; 87: 565-576
20. Lenczowski JM, Dominguez Z, Eder AM, King LB, Zarcharchuk CM, Ashwell JD. Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis. Mol Cell Biol 1997; 17: 170-181
21. Wang KH. An in vitro cell line (MGc80-3) of a pooly differentiated mucoid adenocarcinoma of human stomach. Shiyan Shengwu Xiebao 1983; 16: 257-267
22. Wu Q, Chen ZM, Su WJ. Growth inhibition of gastric cells by all-trans retinoic acid through arresting cell cycle progression. Chin Med J 2001; 114: 958-961
23. Wu Q, Chen ZM, Su WJ. Mechanism of inhibition on activator protein-1 activity by all-trans retinoic acid in gastric cancer cells. Chin Med J 2000; 113: 972-976
24. Wu Q, Li Y, Liu R, Agadir A, Lee MO, Liu Y, Zhang XK. Modulation of retinoic acid sensitivity in lung cancer cells through dynamic balance of orphan receptors nur77 and COUP-TF and their heterodimerization. EMBO J 1997; 16: 1656-1667
25. Liu Y, Lee M, Wang HG, Li Y, Hashimoto Y, Klauss M, Reed JC, Zhang XK. Retinoic acid receptor β mediates the growth-inhibitory effect of retinoic acid by promoting apoptosis in human breast cancer cells. Mol Cell Biol 1996; 16: 1138-1149
26. Li Y, Lin BZ, Agadir A, Liu R, Dawson MI, Reed JC, Fontana JA, Bost F, Hobbs PD, Zheng Y, Chen GQ, Shroot B, Mercola D, Zhang XK. Molecular Determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines. Mol Cell Biol 1998, 18: 4719-4731
27. Karin M. The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 1995; 270: 16843-16846
28. Tsuneo KQ, Xu AF, Kenji N, Masanori K. Selective roles of retinoic acid receptor and retinoid X receptor in the suppression of apoptosis by all-trans-retinoic acid. J Biol Chem 12697-12701
29. Yang-Yen HF, Zhang XK, Graupner G, Tzukerman M, Sakamoto B, Karin M, Pfahl M. Antagonism between retinoic acid receptors and AP-1: Implications for tumor promotion and inflammation. New Biol 1991; 3: 1206-1219
30. Goodnight JA, Mischak H, Kolch W, Mushinski JF. Immunocytochemical localization of eight protein kinase C iaozymes overexpressed in NIH 3T3 fibroblasts. J Biol Chem 1995; 270: 9991-10001
31. Mischak H, Pierce JH, Goodnight J, Martiny BG, Schaechtle C, Kazanieta MG, Blumberg PM, Pierce JH, Mushinski JF. Overexpression of protein kinase C-delta and epsilon in NIH-3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity. J Biol Chem 1993; 268:6090-6096
32. Cross MJ, Stewart A, Hodgkin MN, Kerr DJ, Wakelam MJ. Wortamannin and its structural analogue demethoxyvirdin inhibit stimulated phospholipase A2 activating in Swiss 3T3 cells. J Biol Chem 1995; 270: 25352-25355
33. Bandyopadhyay G, Standaer ML, Galloway L, Moscat J, Farese RV. Evidence for involvement of protein kinase C (PKC) -zeta and noninvolvement of diaclyglycerol-sensitive PKCs in insulin-stimulated glucose transport in L6 myotubes. Endocrinology 1997; 138: 4721-4731
34. House C, Kemp BE. Protein kinase C contains a pseudosubstrate prototope in its regulatory domain. Science 1987; 238: 1726-1728
35. Beatrice C, Manuel P, Heidy SA, Marie M, Violette B, Brnard R, Annie SA. Signal transduction pathways involved in soluble fractalkine-induced monocytic cell adhesion. Blood 2001; 97: 2031-2038
36. Zhou H, Lin AN, Gu ZN, Chen S, Park H, Chiu R. 12-O-tetradecanoylphorbol-13-acetate(TPA)-induced c-jun N-terminal kinase (JNK) phosphatase renders immortalized or transformed epithelial cells refractory to TPA-inducible JNK activity. J Biol Chem 2000; 275: 22868-22874
37. Elisabetta R, Fabio M, Manuela B, Deriso DS. Constitutive activation of the MAPK pathway mediates v-fes-induced mitogenesis in murine macrophages. Blood 2000; 95: 3959-3963
38. Olsou NE, Kozlowski I, Reidy MA. Proliferation of intimal smooth muscle cells. J Biol Chem 2000; 275: 11270-11277
39. Sluss HK, Barrett T, Derijard B, Davis RJ. Signal transduction by tumor necrosis factor mediated by JNK protein kinases. Mol Cell Biol 1994; 14: 8376-8384
40. Butterfield L. Storey B, Maas L, Heasley LE. c-jun N-terminal kinase regulation of the apoptotic response of small cell lung cancer cells to ultraviolet radiation. J Biol Chem 1997; 272: 10110-10116
41. Victoria MM, Yoshihisa I, Javier LCa, Masanori K. Suppression of apoptosis by all-trans retinoic acid. J Biol Chem 1999; 274: 20251-20258
42. Sakata N, Patel HR, Terada N, Araffo A, Johnson GL, Gelfand W. Selective activation of c-jun kinase mitogen-activated protein kinase by CD40 on human B cells. J Biol Chem 1995; 270: 30823-30828
43. Agadir A, Chen GQ, Frederic B, Li Y, Mercola D, Zhang XK. Differential effect of retinoic acid on growth regulation by phorbol ester in human cancer cell lines. J Biol Chem 1999; 274: 29779-29785
44. Huang CS, Li JX, Ma WY, Dong ZG. JNK activation is required for JB6 cell transformation induced by tumor necrosis factor-α but not by TPA. J Biol Chem 1999; 274: 29672-29676
45. Assefa Z, Vantieghem A, Declercq W, Vandenabeele P, Vandenheede JR, Merlevede W, Witte P, Agostinis P. The activation of the JNK and p38 MAPK signaling pathways protects Hela cells from apoptosis following photodynamic therapy with hypericin. J Biol Chem 1999; 274: 8788-8796
46. Karin M. Signal transduction from the cell surface to the nucleus through the phosphorylation of transcription factors. Curr Opin Cell Biol 1994; 6: 415-424
47. Van DH, Wilhelm D, Herr I, Steffwn A, Herrlich P, Angel P. ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents. EMBO J 1995; 14: 1798-1811
48. Wu Q, Liu S, Ding L, Ye XF, Su WJ. PKC α translocation from mitochondria to nucleus is closely related to induction of apoptosis in gastric cancer cells. Zhongguo Kexue 2002; 32:40-45
49. Liu S, Wu Q, Ye XF, Cai JH, Huang ZW, Su WJ. Induction of apoptosis by TPA and VP-16 is through the translocation of TR3. World J Gastroenterol 2002; 8: 446-450