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Volumn 3, Issue 3, 2004, Pages 165-173

Angiogenesis-targeted therapies in prostate cancer

Author keywords

Atrasentan; Bevacizumab; Endothelin; Matrix metalloproteinases; Vascular endothelial growth factor

Indexed keywords

4 (4 FLUORO 2 METHYL 5 INDOLYLOXY) 6 METHOXY 7 [3 (1 PYRROLIDINYL)PROPOXY]QUINAZOLINE; ANTINEOPLASTIC AGENT; ATRASENTAN; BEVACIZUMAB; DOCETAXEL; ENDOTHELIN; EPHRIN; ESTRAMUSTINE; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; MITOXANTRONE; PREDNISONE; PRINOMASTAT; REBIMASTAT; SORAFENIB; SUNITINIB; SURAMIN; TAXANE DERIVATIVE; THALIDOMIDE; UNCLASSIFIED DRUG; VASCULOTROPIN; VATALANIB;

EID: 11144232324     PISSN: 15400352     EISSN: None     Source Type: Journal    
DOI: 10.3816/CGC.2004.n.027     Document Type: Review
Times cited : (22)

References (147)
  • 2
    • 4344581684 scopus 로고    scopus 로고
    • American Society of Clinical Oncology recommendations for the initial hormonal management of androgen-sensidve metastatic, recurrent, or progressive prostate cancer
    • Loblaw DA, Mendelson DS, Talcott JA, et al. American Society of Clinical Oncology recommendations for the initial hormonal management of androgen-sensidve metastatic, recurrent, or progressive prostate cancer. J Clin Oncol 2004; 22:2927-2941.
    • (2004) J Clin Oncol , vol.22 , pp. 2927-2941
    • Loblaw, D.A.1    Mendelson, D.S.2    Talcott, J.A.3
  • 3
    • 0028805834 scopus 로고
    • Hormone-refractory (D3) prostate cancer: Refining the concept
    • Scher HI, Steineck G, Kelly WK. Hormone-refractory (D3) prostate cancer: refining the concept. Urology 1995; 46:142-148.
    • (1995) Urology , vol.46 , pp. 142-148
    • Scher, H.I.1    Steineck, G.2    Kelly, W.K.3
  • 4
    • 0032747375 scopus 로고    scopus 로고
    • Eligibility and response guidelines for phase II clinical trials in androgen-independent prostate cancer: Recommendations from the Prostate-Specific Antigen Working Group
    • Bubley GJ, Carducci M, Dahut W, et al. Eligibility and response guidelines for phase II clinical trials in androgen-independent prostate cancer: recommendations from the Prostate-Specific Antigen Working Group. J Clin Oncol 1999; 17:3461-3467.
    • (1999) J Clin Oncol , vol.17 , pp. 3461-3467
    • Bubley, G.J.1    Carducci, M.2    Dahut, W.3
  • 5
    • 0027944451 scopus 로고
    • Effects of continued androgen-deprivation therapy and other prognostic factors on response and survival in phase II chemotherapy trials for hormone-refractory prostate cancer: A Southwest Oncology Group report
    • Hussain M, Wolf M, Marshall E, et al. Effects of continued androgen-deprivation therapy and other prognostic factors on response and survival in phase II chemotherapy trials for hormone-refractory prostate cancer: a Southwest Oncology Group report. J Clin Oncol 1994; 12:1868-1875.
    • (1994) J Clin Oncol , vol.12 , pp. 1868-1875
    • Hussain, M.1    Wolf, M.2    Marshall, E.3
  • 6
    • 0036789479 scopus 로고    scopus 로고
    • Nomogram for overall survival of patients with progressive metastatic prostate cancer after castration
    • Smaletz O, Scher H I, Small E, et al. Nomogram for overall survival of patients with progressive metastatic prostate cancer after castration. J Clin Oncol 2002; 20:3972-3982.
    • (2002) J Clin Oncol , vol.20 , pp. 3972-3982
    • Smaletz, O.1    Scher, H.I.2    Small, E.3
  • 7
    • 0032784113 scopus 로고    scopus 로고
    • Hydrocortisone with or without mitoxantrone in men with hormone-refractory prostate cancer: Results of the cancer and leukemia group B 9182 study
    • Kantoff PW, Halabi S, Conaway M, et al. Hydrocortisone with or without mitoxantrone in men with hormone-refractory prostate cancer: results of the cancer and leukemia group B 9182 study. J Clin Oncol 1999; 17:2506-2513.
    • (1999) J Clin Oncol , vol.17 , pp. 2506-2513
    • Kantoff, P.W.1    Halabi, S.2    Conaway, M.3
  • 8
    • 0035695399 scopus 로고    scopus 로고
    • Treatment options in hormone-refractory prostate cancer: Current and future approaches
    • Harris KA, Reese DM. Treatment options in hormone-refractory prostate cancer: current and future approaches. Drugs 2001; 61:2177-2192.
    • (2001) Drugs , vol.61 , pp. 2177-2192
    • Harris, K.A.1    Reese, D.M.2
  • 9
    • 4744337716 scopus 로고    scopus 로고
    • Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer
    • Petrylak DP, Tangen CM, Hussain MH, et al. Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. N Engl J Med 2004; 351:1513-1520.
    • (2004) N Engl J Med , vol.351 , pp. 1513-1520
    • Petrylak, D.P.1    Tangen, C.M.2    Hussain, M.H.3
  • 10
    • 4744366279 scopus 로고    scopus 로고
    • Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
    • Tannock IF, de Wit R, Berry WR, et al. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N Engl J Med 2004; 351:1502-1512.
    • (2004) N Engl J Med , vol.351 , pp. 1502-1512
    • Tannock, I.F.1    De Wit, R.2    Berry, W.R.3
  • 11
    • 0028224534 scopus 로고
    • Cell biological mechanisms of multidrug resistance in tumors
    • Simon SM, Schindler M. Cell biological mechanisms of multidrug resistance in tumors. Proc Natl Acad Sci U S A 1994; 91:3497-3504.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 3497-3504
    • Simon, S.M.1    Schindler, M.2
  • 12
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 13
    • 0023992695 scopus 로고
    • Endothelial cell growth factors in embryonic and adult chick brain are related to human acidic fibroblast growth factor
    • Risau W, Gautschi-Sova P, Bohlen P. Endothelial cell growth factors in embryonic and adult chick brain are related to human acidic fibroblast growth factor. EMBO J 1988; 7:959-962.
    • (1988) EMBO J , vol.7 , pp. 959-962
    • Risau, W.1    Gautschi-Sova, P.2    Bohlen, P.3
  • 14
    • 0032577571 scopus 로고    scopus 로고
    • Vasculogenesis, angiogenesis, and growth factors: Ephrins enter the fray at the border
    • Yancopoulos GD, Klagsbrun M, Folkman J. Vasculogenesis, angiogenesis, and growth factors: ephrins enter the fray at the border. Cell 1998; 93:661-664.
    • (1998) Cell , vol.93 , pp. 661-664
    • Yancopoulos, G.D.1    Klagsbrun, M.2    Folkman, J.3
  • 16
    • 0030952289 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis
    • Risau W. Mechanisms of angiogenesis. Nature 1997; 386:671-674.
    • (1997) Nature , vol.386 , pp. 671-674
    • Risau, W.1
  • 17
    • 18644382318 scopus 로고    scopus 로고
    • Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by angiopoietin-1
    • Gale NW, Thurston G, Hackett SF, et al. Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by angiopoietin-1. Dev Cell 2002; 3:411-423.
    • (2002) Dev Cell , vol.3 , pp. 411-423
    • Gale, N.W.1    Thurston, G.2    Hackett, S.F.3
  • 18
    • 15144358851 scopus 로고    scopus 로고
    • Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
    • Maisonpierre PC, Suri C, Jones PF, et al. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 1997; 277:55-60.
    • (1997) Science , vol.277 , pp. 55-60
    • Maisonpierre, P.C.1    Suri, C.2    Jones, P.F.3
  • 19
    • 0033601357 scopus 로고    scopus 로고
    • Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1
    • Thurston G, Suri C, Smith K, et al. Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1. Science 1999; 286:2511-2514.
    • (1999) Science , vol.286 , pp. 2511-2514
    • Thurston, G.1    Suri, C.2    Smith, K.3
  • 20
    • 0035255001 scopus 로고    scopus 로고
    • Differential inhibition of tumor angiogenesis by tie2 and vascular endothelial growth factor receptor-2 dominant-negative receptor mutants
    • Stratmann A, Acker T, Burger A, et al. Differential inhibition of tumor angiogenesis by tie2 and vascular endothelial growth factor receptor-2 dominant-negative receptor mutants. Int J Cancer 2001; 91:273-282.
    • (2001) Int J Cancer , vol.91 , pp. 273-282
    • Stratmann, A.1    Acker, T.2    Burger, A.3
  • 21
    • 0035865227 scopus 로고    scopus 로고
    • Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth-muscle cells
    • Gale NW, Baluk P, Pan L, et al. Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth-muscle cells. Dev Biol 2001; 230:151-160.
    • (2001) Dev Biol , vol.230 , pp. 151-160
    • Gale, N.W.1    Baluk, P.2    Pan, L.3
  • 22
    • 0033197535 scopus 로고    scopus 로고
    • Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development
    • Gerety SS, Wang HU, Chen ZF, et al. Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development. Mol Cell 1999; 4:403-414.
    • (1999) Mol Cell , vol.4 , pp. 403-414
    • Gerety, S.S.1    Wang, H.U.2    Chen, Z.F.3
  • 23
    • 0032577446 scopus 로고    scopus 로고
    • Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4
    • Wang HU, Chen ZF, Anderson DJ. Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell 1998; 93:741-753.
    • (1998) Cell , vol.93 , pp. 741-753
    • Wang, H.U.1    Chen, Z.F.2    Anderson, D.J.3
  • 24
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1995; 1:27-31.
    • (1995) Nat Med , vol.1 , pp. 27-31
    • Folkman, J.1
  • 25
    • 0022648938 scopus 로고
    • How is blood vessel growth regulated in normal and neoplastic tissue? G.H.A. Clowes memorial Award lecture
    • Folkman J. How is blood vessel growth regulated in normal and neoplastic tissue? G.H.A. Clowes memorial Award lecture. Cancer Res 1986; 46:467-473.
    • (1986) Cancer Res , vol.46 , pp. 467-473
    • Folkman, J.1
  • 26
    • 0013680848 scopus 로고
    • Vascular relationships of tumor and host
    • Day ED. Vascular relationships of tumor and host. Prog Exp Tumor Res 1964; 19:57-97.
    • (1964) Prog Exp Tumor Res , vol.19 , pp. 57-97
    • Day, E.D.1
  • 27
    • 0015008620 scopus 로고
    • Isolation of a tumor factor responsible for angiogenesis
    • Folkman J, Merler E, Abernathy C, et al. Isolation of a tumor factor responsible for angiogenesis. J Exp Med 1971; 133:275-288.
    • (1971) J Exp Med , vol.133 , pp. 275-288
    • Folkman, J.1    Merler, E.2    Abernathy, C.3
  • 28
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971; 285:1182-1186.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 29
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350:2335-2342.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 30
    • 0001830867 scopus 로고
    • Tumor angiogenesis
    • Mendelsohn J, Howley PM, Israel MA, et al, eds. Philadelphia: WB Saunders
    • Folkman J. Tumor angiogenesis. In: Mendelsohn J, Howley PM, Israel MA, et al, eds. The Molecular Basis of Cancer. Philadelphia: WB Saunders, 1995:206-232.
    • (1995) The Molecular Basis of Cancer , pp. 206-232
    • Folkman, J.1
  • 31
    • 6944230090 scopus 로고    scopus 로고
    • Effects of angiogenesis inhibitors on vascular network formation by human endothelial and melanoma cells
    • van der Schaft DW, Seftor RE, Seftor EA, et al. Effects of angiogenesis inhibitors on vascular network formation by human endothelial and melanoma cells. J Natl Cancer Inst 2004; 96:1473-1477.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 1473-1477
    • Van Der Schaft, D.W.1    Seftor, R.E.2    Seftor, E.A.3
  • 32
    • 0038143145 scopus 로고    scopus 로고
    • Vasculogenic mimicry and tumour-cell plasticity: Lessons from melanoma
    • Hendrix MJ, Seftor EA, Hess AR, et al. Vasculogenic mimicry and tumour-cell plasticity: lessons from melanoma. Nat Rev Cancer 2003; 3:411-421.
    • (2003) Nat Rev Cancer , vol.3 , pp. 411-421
    • Hendrix, M.J.1    Seftor, E.A.2    Hess, A.R.3
  • 33
    • 0037083432 scopus 로고    scopus 로고
    • Prostatic tumor cell plasticity involves cooperative interactions of distinct phenotypic subpopulations: Role in vasculogenic mimicry
    • Sharma N, Seftor RE, Seftor EA, et al. Prostatic tumor cell plasticity involves cooperative interactions of distinct phenotypic subpopulations: role in vasculogenic mimicry. Prostate 2002; 50:189-201.
    • (2002) Prostate , vol.50 , pp. 189-201
    • Sharma, N.1    Seftor, R.E.2    Seftor, E.A.3
  • 34
    • 0028227085 scopus 로고
    • Tumor microvessel density, p53 expression, tumor size, and peritumoral lymphatic vessel invasion are relevant prognostic markers in node- negative breast carcinoma
    • Gasparini G, Weidner N, Bevilacqua P, et al. Tumor microvessel density, p53 expression, tumor size, and peritumoral lymphatic vessel invasion are relevant prognostic markers in node- negative breast carcinoma. J Clin Oncol 1994; 12:454-466.
    • (1994) J Clin Oncol , vol.12 , pp. 454-466
    • Gasparini, G.1    Weidner, N.2    Bevilacqua, P.3
  • 35
    • 0030993053 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) expression in prostate cancer and benign prostatic hyperplasia
    • Jackson MW, Bentel JM, Tilley WD. Vascular endothelial growth factor (VEGF) expression in prostate cancer and benign prostatic hyperplasia. J Urol 1997; 157:2323-2328.
    • (1997) J Urol , vol.157 , pp. 2323-2328
    • Jackson, M.W.1    Bentel, J.M.2    Tilley, W.D.3
  • 36
    • 0031046552 scopus 로고    scopus 로고
    • Tumor angiogenesis correlates with progression after radical prostatectomy but not with pathologic stage in Gleason sum 5 to 7 adenocarcinoma of the prostate
    • Silberman MA, Partin AW, Veltri RW et al. Tumor angiogenesis correlates with progression after radical prostatectomy but not with pathologic stage in Gleason sum 5 to 7 adenocarcinoma of the prostate. Cancer 1997; 79:772-779.
    • (1997) Cancer , vol.79 , pp. 772-779
    • Silberman, M.A.1    Partin, A.W.2    Veltri, R.W.3
  • 37
    • 0031740741 scopus 로고    scopus 로고
    • An analysis of microvessel density, androgen receptor, p53 and HER-2/neu expression and Gleason score in prostate cancer preliminary results and therapeutic implications
    • Mydlo JH, Kral JG, Volpe M, et al. An analysis of microvessel density, androgen receptor, p53 and HER-2/neu expression and Gleason score in prostate cancer preliminary results and therapeutic implications. Eur Urol 1998; 34:426-432.
    • (1998) Eur Urol , vol.34 , pp. 426-432
    • Mydlo, J.H.1    Kral, J.G.2    Volpe, M.3
  • 38
    • 0027717345 scopus 로고
    • Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma
    • Weidner N, Carroll PR, Flax J, et al. Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Am J Pathol 1993; 143:401-409.
    • (1993) Am J Pathol , vol.143 , pp. 401-409
    • Weidner, N.1    Carroll, P.R.2    Flax, J.3
  • 39
    • 0031710964 scopus 로고    scopus 로고
    • Microvessel density predicts survival in prostate cancer patients subjected to watchful waiting
    • Borre M, Offersen BV, Nerstrom B, et al. Microvessel density predicts survival in prostate cancer patients subjected to watchful waiting. Br J Cancer 1998; 78:940-944.
    • (1998) Br J Cancer , vol.78 , pp. 940-944
    • Borre, M.1    Offersen, B.V.2    Nerstrom, B.3
  • 40
    • 0034069026 scopus 로고    scopus 로고
    • Association between immunohistochemical expression of vascular endothelial growth factor (VEGF), VEGF-expressing neuroendocrine-differentiated tumor cells, and outcome in prostate cancer patients subjected to watchful waiting
    • Borre M, Nerstrom B, Overgaard J. Association between immunohistochemical expression of vascular endothelial growth factor (VEGF), VEGF-expressing neuroendocrine-differentiated tumor cells, and outcome in prostate cancer patients subjected to watchful waiting. Clin Cancer Res 2000; 6:1882-1890.
    • (2000) Clin Cancer Res , vol.6 , pp. 1882-1890
    • Borre, M.1    Nerstrom, B.2    Overgaard, J.3
  • 41
    • 0032935293 scopus 로고    scopus 로고
    • Amplification of the androgen receptor gene is associated with P53 mutation in hormone-refractory recurrent prostate cancer
    • Koivisto PA, Rantala I. Amplification of the androgen receptor gene is associated with P53 mutation in hormone-refractory recurrent prostate cancer. J Pathol 1999; 187:237-241.
    • (1999) J Pathol , vol.187 , pp. 237-241
    • Koivisto, P.A.1    Rantala, I.2
  • 42
    • 0037930504 scopus 로고    scopus 로고
    • The relation of p53 protein nuclear accumulation and angiogenesis in human prostate cancer
    • Yu ED, Yu E, Meyer GE, et al. The relation of p53 protein nuclear accumulation and angiogenesis in human prostate cancer. Prostate Cancer Prostate Dis 1997; 1:39-44.
    • (1997) Prostate Cancer Prostate Dis , vol.1 , pp. 39-44
    • Yu, E.D.1    Yu, E.2    Meyer, G.E.3
  • 43
    • 0033767659 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and its correlation with angiogenesis and p53 expression in prostate cancer
    • Strohmeyer D, Rossing C, Bauerfeind A, et al. Vascular endothelial growth factor and its correlation with angiogenesis and p53 expression in prostate cancer. Prostate 2000; 45:216-224.
    • (2000) Prostate , vol.45 , pp. 216-224
    • Strohmeyer, D.1    Rossing, C.2    Bauerfeind, A.3
  • 44
    • 0035819518 scopus 로고    scopus 로고
    • Angiogenic potential of prostate carcinoma cells overexpressing bcl-2
    • Fernandez A, Udagawa T, Schwesinger C, et al. Angiogenic potential of prostate carcinoma cells overexpressing bcl-2. J Natl Cancer Inst 2001; 93:208-213.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 208-213
    • Fernandez, A.1    Udagawa, T.2    Schwesinger, C.3
  • 45
    • 0031938669 scopus 로고    scopus 로고
    • Angiogenesis and prostate cancer: In vivo and in vitro expression of angiogenesis factors by prostate cancer cells
    • Ferrer FA, Miller LJ, Andrawis RI, et al. Angiogenesis and prostate cancer: in vivo and in vitro expression of angiogenesis factors by prostate cancer cells. Urology 1998; 51:161-167.
    • (1998) Urology , vol.51 , pp. 161-167
    • Ferrer, F.A.1    Miller, L.J.2    Andrawis, R.I.3
  • 46
    • 0038004462 scopus 로고    scopus 로고
    • Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3′-kinase/protein kinase B in prostate cancer cells
    • Mabjeesh NJ, Willard MT, Frederickson CE, et al. Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3′-kinase/protein kinase B in prostate cancer cells. Clin Cancer Res 2003; 9:2416-2425.
    • (2003) Clin Cancer Res , vol.9 , pp. 2416-2425
    • Mabjeesh, N.J.1    Willard, M.T.2    Frederickson, C.E.3
  • 47
    • 0027197245 scopus 로고
    • Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
    • Kim KJ, Li B, Winer J, et al. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 1993; 362:841-844.
    • (1993) Nature , vol.362 , pp. 841-844
    • Kim, K.J.1    Li, B.2    Winer, J.3
  • 48
    • 0031417489 scopus 로고    scopus 로고
    • Androgens regulate vascular endothelial growth factor content in normal and malignant prostatic tissue
    • Joseph IB, Nelson JB, Denmeade SR, et al. Androgens regulate vascular endothelial growth factor content in normal and malignant prostatic tissue. Clin Cancer Res 1997; 3:2507-2511.
    • (1997) Clin Cancer Res , vol.3 , pp. 2507-2511
    • Joseph, I.B.1    Nelson, J.B.2    Denmeade, S.R.3
  • 49
    • 0035176826 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression and rumor angiogenesis are regulated by androgens in hormone responsive human prostate carcinoma: Evidence for androgen dependent destabilization of vascular endothelial growth factor transcripts
    • Stewart RJ, Panigrahy D, Flynn E, et al. Vascular endothelial growth factor expression and rumor angiogenesis are regulated by androgens in hormone responsive human prostate carcinoma: evidence for androgen dependent destabilization of vascular endothelial growth factor transcripts. J Urol 2001; 165:688-693.
    • (2001) J Urol , vol.165 , pp. 688-693
    • Stewart, R.J.1    Panigrahy, D.2    Flynn, E.3
  • 50
    • 0032500848 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is up-regulated in vitro and in vivo by androgens
    • Sordello S, Bertrand N, Plouet J. Vascular endothelial growth factor is up-regulated in vitro and in vivo by androgens. Biochem Biophys Res Commun 1998; 251:287-290.
    • (1998) Biochem Biophys Res Commun , vol.251 , pp. 287-290
    • Sordello, S.1    Bertrand, N.2    Plouet, J.3
  • 51
    • 0033674846 scopus 로고    scopus 로고
    • Neuropilin-1 expression by tumor cells promotes tumor angiogenesis and progression
    • Miao HQ, Lee P, Lin H, et al. Neuropilin-1 expression by tumor cells promotes tumor angiogenesis and progression. FASEB J 2000; 14:2532-2539.
    • (2000) FASEB J , vol.14 , pp. 2532-2539
    • Miao, H.Q.1    Lee, P.2    Lin, H.3
  • 52
    • 0036468225 scopus 로고    scopus 로고
    • Androgens modulate the balance between VEGF and angiopoietin expression in prostate epithelial and smooth muscle cells
    • Richard C, Kim G, Koikawa Y, et al. Androgens modulate the balance between VEGF and angiopoietin expression in prostate epithelial and smooth muscle cells. Prostate 2002; 50:83-91.
    • (2002) Prostate , vol.50 , pp. 83-91
    • Richard, C.1    Kim, G.2    Koikawa, Y.3
  • 53
    • 0034646262 scopus 로고    scopus 로고
    • Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor: In vivo expression and antitumor activity
    • Gagnon ML, Bielenberg DR, Gechtman Z, et al. Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor: In vivo expression and antitumor activity. Proc Natl Acad Sci U S A 2000; 97:2573-2578.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 2573-2578
    • Gagnon, M.L.1    Bielenberg, D.R.2    Gechtman, Z.3
  • 54
    • 1642515774 scopus 로고    scopus 로고
    • Activator protein 2a inhibits tumorigenicity and represses vascular endothelial growth factor transcription in prostate cancer cells
    • Ruiz M, Pettaway C, Song R, et al. Activator protein 2a inhibits tumorigenicity and represses vascular endothelial growth factor transcription in prostate cancer cells. Cancer Res 2004; 64:631-638.
    • (2004) Cancer Res , vol.64 , pp. 631-638
    • Ruiz, M.1    Pettaway, C.2    Song, R.3
  • 55
    • 0038079838 scopus 로고    scopus 로고
    • Bombesin stimulates nuclear factor kappa B activation and expression of proangiogenic factors in prostate cancer cells
    • Levine L, Lucci JA III, Pazdrak B, et al. Bombesin stimulates nuclear factor kappa B activation and expression of proangiogenic factors in prostate cancer cells. Cancer Res 2003; 63:3495-3502.
    • (2003) Cancer Res , vol.63 , pp. 3495-3502
    • Levine, L.1    Lucci III, J.A.2    Pazdrak, B.3
  • 56
    • 0032838197 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor receptors in human prostate cancer
    • Ferrer FA, Miller LJ, Lindquist R, et al. Expression of vascular endothelial growth factor receptors in human prostate cancer. Urology 1999; 54:567-572.
    • (1999) Urology , vol.54 , pp. 567-572
    • Ferrer, F.A.1    Miller, L.J.2    Lindquist, R.3
  • 57
    • 0033844219 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression and capillary architecture in high-grade PIN and prostate cancer in untreated and androgen-ablated patients
    • Mazzucchelli R, Montironi R, Santinelli A, et al. Vascular endothelial growth factor expression and capillary architecture in high-grade PIN and prostate cancer in untreated and androgen-ablated patients. Prostate 2000; 45:72-79.
    • (2000) Prostate , vol.45 , pp. 72-79
    • Mazzucchelli, R.1    Montironi, R.2    Santinelli, A.3
  • 58
    • 0037187334 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and signaling in the prostate: More than angiogenesis
    • Chevalier S, Defoy I, Lacoste J, et al. Vascular endothelial growth factor and signaling in the prostate: more than angiogenesis. Mol Cell Endocrinol 2002; 189:169-179.
    • (2002) Mol Cell Endocrinol , vol.189 , pp. 169-179
    • Chevalier, S.1    Defoy, I.2    Lacoste, J.3
  • 59
    • 0029774076 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) expression in prostatic tumours and its relationship to neuroendocrine cells
    • Harper ME, Glynne-Jones E, Goddard L, et al. Vascular endothelial growth factor (VEGF) expression in prostatic tumours and its relationship to neuroendocrine cells. Br J Cancer 1996; 74:910-916.
    • (1996) Br J Cancer , vol.74 , pp. 910-916
    • Harper, M.E.1    Glynne-Jones, E.2    Goddard, L.3
  • 60
    • 2442701925 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor-A in human lymph node metastases of prostate cancer
    • Ismail AH, Altaweel W, Chevalier S, et al. Expression of vascular endothelial growth factor-A in human lymph node metastases of prostate cancer. Can J Urol 2004; 11:2146-2150.
    • (2004) Can J Urol , vol.11 , pp. 2146-2150
    • Ismail, A.H.1    Altaweel, W.2    Chevalier, S.3
  • 61
    • 0034128221 scopus 로고    scopus 로고
    • Suramin therapy for patients with symptomatic hormone-refractory prostate cancer: Results of a randomized phase III trial comparing suramin plus hydrocortisone to placebo plus hydrocortisone
    • Small EJ, Meyer M, Marshall ME, et al. Suramin therapy for patients with symptomatic hormone-refractory prostate cancer: results of a randomized phase III trial comparing suramin plus hydrocortisone to placebo plus hydrocortisone. J Clin Oncol 2000; 18:1440-1450.
    • (2000) J Clin Oncol , vol.18 , pp. 1440-1450
    • Small, E.J.1    Meyer, M.2    Marshall, M.E.3
  • 62
    • 0034772250 scopus 로고    scopus 로고
    • Prognostic significance of plasma vascular endothelial growth factor levels in patients with hormone-refractory prostate cancer treated on Cancer and Leukemia Group B 9480
    • George DJ, Halabi S, Shepard TF, et al. Prognostic significance of plasma vascular endothelial growth factor levels in patients with hormone-refractory prostate cancer treated on Cancer and Leukemia Group B 9480. Clin Cancer Res 2001; 7:1932-1936.
    • (2001) Clin Cancer Res , vol.7 , pp. 1932-1936
    • George, D.J.1    Halabi, S.2    Shepard, T.F.3
  • 63
    • 2442641793 scopus 로고    scopus 로고
    • Association of preoperative plasma levels of vascular endothelial growth factor and soluble vascular cell adhesion molecule-1 with lymph node status and biochemical progression after radical prostatectomy
    • Shariat SF, Anwuri VA, Lamb DJ, et al. Association of preoperative plasma levels of vascular endothelial growth factor and soluble vascular cell adhesion molecule-1 with lymph node status and biochemical progression after radical prostatectomy. J Clin Oncol 2004; 22:1655-1663.
    • (2004) J Clin Oncol , vol.22 , pp. 1655-1663
    • Shariat, S.F.1    Anwuri, V.A.2    Lamb, D.J.3
  • 64
    • 1442339457 scopus 로고    scopus 로고
    • Urinary VEGF and MMP levels as predictive markers of 1-year progression-free survival in cancer patients treated with radiation therapy: A longitudinal study of protein kinetics throughout tumor progression and therapy
    • Chan LW, Moses MA, Goley E, et al. Urinary VEGF and MMP levels as predictive markers of 1-year progression-free survival in cancer patients treated with radiation therapy: a longitudinal study of protein kinetics throughout tumor progression and therapy. J Clin Oncol 2004; 22:499-506.
    • (2004) J Clin Oncol , vol.22 , pp. 499-506
    • Chan, L.W.1    Moses, M.A.2    Goley, E.3
  • 65
    • 10744222232 scopus 로고    scopus 로고
    • Radical prostatectomy lowers plasma vascular endothelial growth factor levels in patients with prostate cancer
    • George DJ, Regan MM, Oh WK, et al. Radical prostatectomy lowers plasma vascular endothelial growth factor levels in patients with prostate cancer. Urology 2004; 63:327-332.
    • (2004) Urology , vol.63 , pp. 327-332
    • George, D.J.1    Regan, M.M.2    Oh, W.K.3
  • 66
    • 0037380232 scopus 로고    scopus 로고
    • Prospective study of circulating angiogenic markers in prostate-specific antigen (PSA)-stable and PSA-progressive hormone-sensitive advanced prostate cancer
    • Kohli M, Kaushal V, Spencer HJ, et al. Prospective study of circulating angiogenic markers in prostate-specific antigen (PSA)-stable and PSA-progressive hormone-sensitive advanced prostate cancer. Urology 2003; 61:765-769.
    • (2003) Urology , vol.61 , pp. 765-769
    • Kohli, M.1    Kaushal, V.2    Spencer, H.J.3
  • 67
    • 0036282502 scopus 로고    scopus 로고
    • Inhibition of angiogenesis: Treatment options for patients with metastatic prostate cancer
    • Figg WD, Kruger EA, Price DK, et al. Inhibition of angiogenesis: treatment options for patients with metastatic prostate cancer. Invest New Drugs 2002; 20:183-194.
    • (2002) Invest New Drugs , vol.20 , pp. 183-194
    • Figg, W.D.1    Kruger, E.A.2    Price, D.K.3
  • 68
    • 4143136640 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Basic science and clinical progress
    • Ferrara N. Vascular endothelial growth factor: basic science and clinical progress. Endocr Rev 2004; 25:581-611.
    • (2004) Endocr Rev , vol.25 , pp. 581-611
    • Ferrara, N.1
  • 69
    • 0034950008 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor (VEGF) and VEGF receptor Flk-1 in benign, premalignant, and malignant prostate tissue
    • Kollermann J, Helpap B. Expression of vascular endothelial growth factor (VEGF) and VEGF receptor Flk-1 in benign, premalignant, and malignant prostate tissue. Am J Clin Pathol 2001; 116:115-121.
    • (2001) Am J Clin Pathol , vol.116 , pp. 115-121
    • Kollermann, J.1    Helpap, B.2
  • 70
    • 2942556514 scopus 로고    scopus 로고
    • The VEGF receptor flt-1 (VEGFR-1) is a positive modulator of vascular sprout formation and branching morphogenesis
    • Kearney JB, Kappas NC, Ellerstrom C, et al. The VEGF receptor flt-1 (VEGFR-1) is a positive modulator of vascular sprout formation and branching morphogenesis. Blood 2004; 103:4527-4535.
    • (2004) Blood , vol.103 , pp. 4527-4535
    • Kearney, J.B.1    Kappas, N.C.2    Ellerstrom, C.3
  • 71
    • 2942511783 scopus 로고    scopus 로고
    • An angiogenic switch in breast cancer involves estrogen and soluble vascular endothelial growth factor receptor 1
    • Elkin M, Orgel A, Kleinman HK. An angiogenic switch in breast cancer involves estrogen and soluble vascular endothelial growth factor receptor 1. J Natl Cancer Inst 2004; 96:875-878.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 875-878
    • Elkin, M.1    Orgel, A.2    Kleinman, H.K.3
  • 72
    • 11144353700 scopus 로고    scopus 로고
    • Suppression of VEGFR-3 signaling inhibits lymph node metastasis in gastric cancer
    • Shimizu K, Kubo H, Yamaguchi K, et al. Suppression of VEGFR-3 signaling inhibits lymph node metastasis in gastric cancer. Cancer Sci 2004; 95:328-333.
    • (2004) Cancer Sci , vol.95 , pp. 328-333
    • Shimizu, K.1    Kubo, H.2    Yamaguchi, K.3
  • 73
    • 0036468930 scopus 로고    scopus 로고
    • A potential autocrine role for vascular endothelial growth factor in prostate cancer
    • Jackson MW, Roberts JS, Heckford SE, et al. A potential autocrine role for vascular endothelial growth factor in prostate cancer. Cancer Res 2002; 62:854-859.
    • (2002) Cancer Res , vol.62 , pp. 854-859
    • Jackson, M.W.1    Roberts, J.S.2    Heckford, S.E.3
  • 74
    • 0036023438 scopus 로고    scopus 로고
    • Anti-vascular endothelial growth factor receptor 2 antibody reduces tumorigenicity and metastasis in orthotopic prostate cancer xenografrs via induction of endothelial cell apoptosis and reduction of endothelial cell matrix metalloproteinase type 9 production
    • Sweeney P, Karashima T, Kim SJ, et al. Anti-vascular endothelial growth factor receptor 2 antibody reduces tumorigenicity and metastasis in orthotopic prostate cancer xenografrs via induction of endothelial cell apoptosis and reduction of endothelial cell matrix metalloproteinase type 9 production. Clin Cancer Res 2002; 8:2714-2724.
    • (2002) Clin Cancer Res , vol.8 , pp. 2714-2724
    • Sweeney, P.1    Karashima, T.2    Kim, S.J.3
  • 75
    • 0035866779 scopus 로고    scopus 로고
    • Angiogenesis and prostate cancer: Identification of a molecular progression switch
    • Huss WJ, Hanrahan CF, Barrios RJ, et al. Angiogenesis and prostate cancer: identification of a molecular progression switch. Cancer Res 2001; 61:2736-2743.
    • (2001) Cancer Res , vol.61 , pp. 2736-2743
    • Huss, W.J.1    Hanrahan, C.F.2    Barrios, R.J.3
  • 76
    • 10744225879 scopus 로고    scopus 로고
    • Vascular endothelial growth factor contributes to the prostate cancer-induced osteoblast differentiation mediated by bone morphogenetic protein
    • Dai J, Kitagawa Y, Zhang J, et al. Vascular endothelial growth factor contributes to the prostate cancer-induced osteoblast differentiation mediated by bone morphogenetic protein. Cancer Res 2004; 64:994-999.
    • (2004) Cancer Res , vol.64 , pp. 994-999
    • Dai, J.1    Kitagawa, Y.2    Zhang, J.3
  • 77
    • 0742305017 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor receptor-3 (VEGFR-3) in human prostate
    • Li R, Younes M, Wheeler TM, et al. Expression of vascular endothelial growth factor receptor-3 (VEGFR-3) in human prostate. Prostate 2004; 58:193-199.
    • (2004) Prostate , vol.58 , pp. 193-199
    • Li, R.1    Younes, M.2    Wheeler, T.M.3
  • 78
    • 4143135316 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor receptor-3 by lymphatic endothelial cells is associated with lymph node metastasis in prostate cancer
    • Zeng Y, Opeskin K, Baldwin ME, et al. Expression of vascular endothelial growth factor receptor-3 by lymphatic endothelial cells is associated with lymph node metastasis in prostate cancer. Clin Cancer Res 2004; 10:5137-5144.
    • (2004) Clin Cancer Res , vol.10 , pp. 5137-5144
    • Zeng, Y.1    Opeskin, K.2    Baldwin, M.E.3
  • 79
    • 0029851690 scopus 로고    scopus 로고
    • Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands
    • Holland SJ, Gale NW, Mbamalu G, et al. Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands. Nature 1996; 383:722-725.
    • (1996) Nature , vol.383 , pp. 722-725
    • Holland, S.J.1    Gale, N.W.2    Mbamalu, G.3
  • 80
    • 15844429889 scopus 로고    scopus 로고
    • Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis
    • Gale NW, Holland SJ, Valenzuela DM, et al. Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis. Neuron 1996; 17:9-19.
    • (1996) Neuron , vol.17 , pp. 9-19
    • Gale, N.W.1    Holland, S.J.2    Valenzuela, D.M.3
  • 81
    • 0028110068 scopus 로고
    • Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity
    • Davis S, Gale NW, Aldrich TH, et al. Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity. Science 1994; 266:816-819.
    • (1994) Science , vol.266 , pp. 816-819
    • Davis, S.1    Gale, N.W.2    Aldrich, T.H.3
  • 82
    • 0036303033 scopus 로고    scopus 로고
    • Mechanisms and functions of Eph and ephrin signalling
    • Kullander K, Klein R. Mechanisms and functions of Eph and ephrin signalling. Nat Rev Mol Cell Biol 2002; 3:475-486.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 475-486
    • Kullander, K.1    Klein, R.2
  • 83
    • 0036568740 scopus 로고    scopus 로고
    • Ephrins are not only unattractive
    • Holmberg J, Frisen J. Ephrins are not only unattractive. Trends Neurosci 2002; 25:239-243.
    • (2002) Trends Neurosci , vol.25 , pp. 239-243
    • Holmberg, J.1    Frisen, J.2
  • 84
    • 0034626791 scopus 로고    scopus 로고
    • Regulation of repulsion versus adhesion by different splice forms of an Eph receptor
    • Holmberg J, Clarke DL, Frisen J. Regulation of repulsion versus adhesion by different splice forms of an Eph receptor. Nature 2000; 408:203-206.
    • (2000) Nature , vol.408 , pp. 203-206
    • Holmberg, J.1    Clarke, D.L.2    Frisen, J.3
  • 85
    • 0033215333 scopus 로고    scopus 로고
    • Ephrins and their Eph receptors: Multitalented directors of embryonic development
    • Frisen J, Holmberg J, Barbacid M. Ephrins and their Eph receptors: multitalented directors of embryonic development. EMBO J 1999; 18:5159-5165.
    • (1999) EMBO J , vol.18 , pp. 5159-5165
    • Frisen, J.1    Holmberg, J.2    Barbacid, M.3
  • 86
    • 0033135876 scopus 로고    scopus 로고
    • Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development
    • Gale NW, Yancopoulos GD. Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development. Genes Dev 1999; 13:1055-1066.
    • (1999) Genes Dev , vol.13 , pp. 1055-1066
    • Gale, N.W.1    Yancopoulos, G.D.2
  • 87
    • 0036635253 scopus 로고    scopus 로고
    • Ephrins in reverse, park and drive
    • Cowan CA, Henkemeyer M. Ephrins in reverse, park and drive. Trends Cell Biol 2002; 12:339-346.
    • (2002) Trends Cell Biol , vol.12 , pp. 339-346
    • Cowan, C.A.1    Henkemeyer, M.2
  • 88
    • 3042587215 scopus 로고    scopus 로고
    • Bidirectional signaling mediated by ephrin-B2 and EphB2 controls urorectal development
    • Dravis C, Yokoyama N, Chumley MJ, et al. Bidirectional signaling mediated by ephrin-B2 and EphB2 controls urorectal development. Dev Biol 2004; 271:272-290.
    • (2004) Dev Biol , vol.271 , pp. 272-290
    • Dravis, C.1    Yokoyama, N.2    Chumley, M.J.3
  • 89
    • 0037272448 scopus 로고    scopus 로고
    • Molecular control of arterial-venous blood vessel identity
    • Adams RH. Molecular control of arterial-venous blood vessel identity. J Anat 2003; 202:105-112.
    • (2003) J Anat , vol.202 , pp. 105-112
    • Adams, R.H.1
  • 90
    • 0036445885 scopus 로고    scopus 로고
    • Vascular patterning by Eph receptor tyrosine kinases and ephrins
    • Adams RH. Vascular patterning by Eph receptor tyrosine kinases and ephrins. Semin Cell Dev Biol 2002; 13:55-60.
    • (2002) Semin Cell Dev Biol , vol.13 , pp. 55-60
    • Adams, R.H.1
  • 91
    • 0034468383 scopus 로고    scopus 로고
    • Eph receptors and ephrin ligands. Essential mediators of vascular development
    • Adams RH, Klein R. Eph receptors and ephrin ligands. essential mediators of vascular development. Trends Cardiovasc Med 2000; 10:183-188.
    • (2000) Trends Cardiovasc Med , vol.10 , pp. 183-188
    • Adams, R.H.1    Klein, R.2
  • 92
    • 0035846911 scopus 로고    scopus 로고
    • The cytoplasmic domain of the ligand ephrinB2 is required for vascular morphogenesis but not cranial neural crest migration
    • Adams RH, Diella F, Hennig S, et al. The cytoplasmic domain of the ligand ephrinB2 is required for vascular morphogenesis but not cranial neural crest migration. Cell 2001; 104:57-69.
    • (2001) Cell , vol.104 , pp. 57-69
    • Adams, R.H.1    Diella, F.2    Hennig, S.3
  • 93
    • 0033082959 scopus 로고    scopus 로고
    • Roles of ephrin B ligands and EphB receptors in cardiovascular development: Demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis
    • Adams RH, Wilkinson GA, Weiss C, et al. Roles of ephrin B ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis. Genes Dev 1999; 13:295-306.
    • (1999) Genes Dev , vol.13 , pp. 295-306
    • Adams, R.H.1    Wilkinson, G.A.2    Weiss, C.3
  • 94
    • 0029914374 scopus 로고    scopus 로고
    • Concentration of vascular endothelial growth factor in the serum and tumor tissue of brain tumor patients
    • Takano S, Yoshii Y, Kondo S, et al. Concentration of vascular endothelial growth factor in the serum and tumor tissue of brain tumor patients. Cancer Res 1996; 56:2185-2190.
    • (1996) Cancer Res , vol.56 , pp. 2185-2190
    • Takano, S.1    Yoshii, Y.2    Kondo, S.3
  • 95
    • 0042442460 scopus 로고    scopus 로고
    • Control of skeletal patterning by ephrinB1-EphB interactions
    • Compagni A, Logan M, Klein R, et al. Control of skeletal patterning by ephrinB1-EphB interactions. Dev Cell 2003; 5:217-230.
    • (2003) Dev Cell , vol.5 , pp. 217-230
    • Compagni, A.1    Logan, M.2    Klein, R.3
  • 96
    • 0029041253 scopus 로고
    • Membrane-bound LERK2 ligand can signal through three different Eph-related receptor tyrosine kinases
    • Brambilla R, Schnapp A, Casagranda F, et al. Membrane-bound LERK2 ligand can signal through three different Eph-related receptor tyrosine kinases. EMBO J 1995; 14:3116-3126.
    • (1995) EMBO J , vol.14 , pp. 3116-3126
    • Brambilla, R.1    Schnapp, A.2    Casagranda, F.3
  • 97
    • 0038497941 scopus 로고    scopus 로고
    • Forward EphB4 signaling in endothelial cells controls cellular repulsion and segregation from ephrinB2 positive cells
    • Fuller T, Korff T, Kilian A, et al. Forward EphB4 signaling in endothelial cells controls cellular repulsion and segregation from ephrinB2 positive cells. J Cell Sci 2003; 116:2461-2470.
    • (2003) J Cell Sci , vol.116 , pp. 2461-2470
    • Fuller, T.1    Korff, T.2    Kilian, A.3
  • 98
    • 0037324381 scopus 로고    scopus 로고
    • Distinct roles of ephrin-B2 forward and EphB4 reverse signaling in endothelial cells
    • Hamada K, Oike Y, Ito Y, et al. Distinct roles of ephrin-B2 forward and EphB4 reverse signaling in endothelial cells. Arterioscler Thromb Vasc Biol 2003; 23:190-197.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 190-197
    • Hamada, K.1    Oike, Y.2    Ito, Y.3
  • 99
    • 0032968502 scopus 로고    scopus 로고
    • An early developmental role for eph-ephrin interaction during vertebrate gastrulation
    • Oates AC, Lackmann M, Power MA, et al. An early developmental role for eph-ephrin interaction during vertebrate gastrulation. Mech Dev 1999; 83:77-94.
    • (1999) Mech Dev , vol.83 , pp. 77-94
    • Oates, A.C.1    Lackmann, M.2    Power, M.A.3
  • 100
    • 0032966750 scopus 로고    scopus 로고
    • Eph receptors and ephrins in neural development
    • O'Leary DD, Wilkinson DG. Eph receptors and ephrins in neural development. Curr Opin Neurobiol 1999; 9:65-73.
    • (1999) Curr Opin Neurobiol , vol.9 , pp. 65-73
    • O'Leary, D.D.1    Wilkinson, D.G.2
  • 101
    • 0344406286 scopus 로고    scopus 로고
    • Activation of the receptor protein tyrosine kinase EphB4 in endometrial hyperplasia and endometrial carcinoma
    • Berclaz G, Karamitopoulou E, Mazzucchelli L, et al. Activation of the receptor protein tyrosine kinase EphB4 in endometrial hyperplasia and endometrial carcinoma. Ann Oncol 2003; 14:220-226.
    • (2003) Ann Oncol , vol.14 , pp. 220-226
    • Berclaz, G.1    Karamitopoulou, E.2    Mazzucchelli, L.3
  • 102
    • 0030600407 scopus 로고    scopus 로고
    • Expression of the receptor protein tyrosine kinase myk-1/htk in normal and malignant mammary epithelium
    • Berclaz G, Andres AC, Albrecht D, et al. Expression of the receptor protein tyrosine kinase myk-1/htk in normal and malignant mammary epithelium. Biochem Biophys Res Commun 1996; 226:869-875.
    • (1996) Biochem Biophys Res Commun , vol.226 , pp. 869-875
    • Berclaz, G.1    Andres, A.C.2    Albrecht, D.3
  • 103
    • 0034957362 scopus 로고    scopus 로고
    • Estrogen dependent expression of the receptor tyrosine kinase axl in normal and malignant human breast
    • Berclaz G, Altermatt HJ, Rohrbach V, et al. Estrogen dependent expression of the receptor tyrosine kinase axl in normal and malignant human breast. Ann Oncol 2001; 12:819-824.
    • (2001) Ann Oncol , vol.12 , pp. 819-824
    • Berclaz, G.1    Altermatt, H.J.2    Rohrbach, V.3
  • 104
    • 0028788451 scopus 로고
    • A. Protein tyrosine kinase expression during the estrous cycle and carcinogenesis of the mammary gland
    • Andres AC, Zuercher G, Djonov V, et al. A. Protein tyrosine kinase expression during the estrous cycle and carcinogenesis of the mammary gland. Int J Cancer 1995; 63:288-296.
    • (1995) Int J Cancer , vol.63 , pp. 288-296
    • Andres, A.C.1    Zuercher, G.2    Djonov, V.3
  • 105
    • 0031870740 scopus 로고    scopus 로고
    • Genetic alterations in hormone-refractory recurrent prostate carcinomas
    • Nupponen NN, Kakkola L, Koivisto P, et al. Genetic alterations in hormone-refractory recurrent prostate carcinomas. Am J Pathol 1998; 153:141-148.
    • (1998) Am J Pathol , vol.153 , pp. 141-148
    • Nupponen, N.N.1    Kakkola, L.2    Koivisto, P.3
  • 106
    • 0030936323 scopus 로고    scopus 로고
    • PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
    • Li J, Yen C, Liaw D, et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 1997; 275:1943-1947.
    • (1997) Science , vol.275 , pp. 1943-1947
    • Li, J.1    Yen, C.2    Liaw, D.3
  • 107
    • 0032126505 scopus 로고    scopus 로고
    • Frequent inactivation of PTEN in prostate cancer cell lines and xenografts
    • Vlietstra RJ, van Alewijk DC, Hermans KG, et al. Frequent inactivation of PTEN in prostate cancer cell lines and xenografts. Cancer Res 1998; 58:2720-2723.
    • (1998) Cancer Res , vol.58 , pp. 2720-2723
    • Vlietstra, R.J.1    Van Alewijk, D.C.2    Hermans, K.G.3
  • 108
    • 0037303695 scopus 로고    scopus 로고
    • Bone markers in the management of patients with skeletal metastases
    • Demers LM. Bone markers in the management of patients with skeletal metastases. Cancer 2003; 97:874-879.
    • (2003) Cancer , vol.97 , pp. 874-879
    • Demers, L.M.1
  • 110
    • 0037248004 scopus 로고    scopus 로고
    • Characterization of expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in prostate cancer cell lines
    • Daja MM, Niu X, Zhao Z, et al. Characterization of expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in prostate cancer cell lines. Prostate Cancer Prostatic Dis 2003; 6:15-26.
    • (2003) Prostate Cancer Prostatic Dis , vol.6 , pp. 15-26
    • Daja, M.M.1    Niu, X.2    Zhao, Z.3
  • 112
    • 0031026396 scopus 로고    scopus 로고
    • Methylation of the 5′ CpG island of the endothelin B receptor gene is common in human prostate cancer
    • Nelson JB, Lee WH, Nguyen SH, et al. Methylation of the 5′ CpG island of the endothelin B receptor gene is common in human prostate cancer. Cancer Res 1997; 57:35-37.
    • (1997) Cancer Res , vol.57 , pp. 35-37
    • Nelson, J.B.1    Lee, W.H.2    Nguyen, S.H.3
  • 113
    • 0037317520 scopus 로고    scopus 로고
    • The endothelin axis: Emerging role in cancer
    • Nelson J, Bagnato A, Battistini B, et al. The endothelin axis: emerging role in cancer. Nat Rev Cancer 2003; 3:110-116.
    • (2003) Nat Rev Cancer , vol.3 , pp. 110-116
    • Nelson, J.1    Bagnato, A.2    Battistini, B.3
  • 114
    • 0029085123 scopus 로고
    • Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate
    • Nelson JB, Hedican SP, George DJ, et al. Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate. Nat Med 1995; 1:944-949.
    • (1995) Nat Med , vol.1 , pp. 944-949
    • Nelson, J.B.1    Hedican, S.P.2    George, D.J.3
  • 115
    • 0030047858 scopus 로고    scopus 로고
    • Endothelin-1 production and decreased endothelin B receptor expression in advanced prostate cancer
    • Nelson JB, Chan-Tack K, Hedican SP, et al. Endothelin-1 production and decreased endothelin B receptor expression in advanced prostate cancer. Cancer Res 1996; 56:663-668.
    • (1996) Cancer Res , vol.56 , pp. 663-668
    • Nelson, J.B.1    Chan-Tack, K.2    Hedican, S.P.3
  • 116
    • 0031889217 scopus 로고    scopus 로고
    • Neutral endopeptidase 24.11 loss in metastatic human prostate cancer contributes to androgen-independent progression
    • Papandreou CN, Usmani B, Geng Y, et al. Neutral endopeptidase 24.11 loss in metastatic human prostate cancer contributes to androgen-independent progression. Nat Med 1998; 4:50-57.
    • (1998) Nat Med , vol.4 , pp. 50-57
    • Papandreou, C.N.1    Usmani, B.2    Geng, Y.3
  • 117
    • 0035870880 scopus 로고    scopus 로고
    • The endothelin receptor B (EDNRB) promoter displays heterogeneous, site specific methylation patterns in normal and tumor cells
    • Pao MM, Tsutsumi M, Liang G, et al. The endothelin receptor B (EDNRB) promoter displays heterogeneous, site specific methylation patterns in normal and tumor cells. Hum Mol Genet 2001; 10:903-910.
    • (2001) Hum Mol Genet , vol.10 , pp. 903-910
    • Pao, M.M.1    Tsutsumi, M.2    Liang, G.3
  • 118
    • 0037245645 scopus 로고    scopus 로고
    • Endothelin B receptor gene hypermethylation in prostate adenocarcinoma
    • Jeronimo C, Henrique R, Campos PF, et al. Endothelin B receptor gene hypermethylation in prostate adenocarcinoma. J Clin Pathol 2003; 56:52-55.
    • (2003) J Clin Pathol , vol.56 , pp. 52-55
    • Jeronimo, C.1    Henrique, R.2    Campos, P.F.3
  • 120
    • 0141479984 scopus 로고    scopus 로고
    • A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases
    • Yin JJ, Mohammad KS, Kakonen SM, et al. A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases. Proc Natl Acad Sci U S A 2003; 100:10954-10959.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 10954-10959
    • Yin, J.J.1    Mohammad, K.S.2    Kakonen, S.M.3
  • 121
    • 0027298410 scopus 로고
    • Suramin: A novel antineoplastic agent with multiple potential mechanisms of action
    • Stein CA. Suramin: a novel antineoplastic agent with multiple potential mechanisms of action. Cancer Res 1993; 53:2239-2248.
    • (1993) Cancer Res , vol.53 , pp. 2239-2248
    • Stein, C.A.1
  • 122
    • 0028318791 scopus 로고
    • Suramin, an anticancer and angiosuppressive agent, inhibits endothelial cell binding of basic fibroblast growth factor, migration, proliferation, and induction of urokinase-type plasminogen activator
    • Takano S, Gately S, Neville ME, et al. Suramin, an anticancer and angiosuppressive agent, inhibits endothelial cell binding of basic fibroblast growth factor, migration, proliferation, and induction of urokinase-type plasminogen activator. Cancer Res 1994; 54:2654-2660.
    • (1994) Cancer Res , vol.54 , pp. 2654-2660
    • Takano, S.1    Gately, S.2    Neville, M.E.3
  • 123
    • 0029120379 scopus 로고
    • Phase I study of suramin given by intermittent infusion without adaptive control in patients with advanced cancer
    • Kobayashi K, Vokes EE, Vogelzang NJ, et al. Phase I study of suramin given by intermittent infusion without adaptive control in patients with advanced cancer. J Clin Oncol 1995; 13:2196-2207.
    • (1995) J Clin Oncol , vol.13 , pp. 2196-2207
    • Kobayashi, K.1    Vokes, E.E.2    Vogelzang, N.J.3
  • 124
    • 0027208069 scopus 로고
    • Recent research on the biological activity of suramin
    • Voogd TE, Vansterkenburg EL, Wilting J, et al. Recent research on the biological activity of suramin. Pharmacol Rev 1993; 45:177-203.
    • (1993) Pharmacol Rev , vol.45 , pp. 177-203
    • Voogd, T.E.1    Vansterkenburg, E.L.2    Wilting, J.3
  • 125
    • 0029127207 scopus 로고
    • Phase I and clinical evaluation of a pharmacologically guided regimen of suramin in patients with hormone-refractory prostate cancer
    • Eisenberger MA, Sinibaldi VJ, Reyno LM, et al. Phase I and clinical evaluation of a pharmacologically guided regimen of suramin in patients with hormone-refractory prostate cancer. J Clin Oncol 1995; 13:2174-2186.
    • (1995) J Clin Oncol , vol.13 , pp. 2174-2186
    • Eisenberger, M.A.1    Sinibaldi, V.J.2    Reyno, L.M.3
  • 126
    • 0029100936 scopus 로고
    • Suramin and hydrocortisone: Determining drug efficacy in androgen-independent prostate cancer
    • Kelly WK, Scher HI, Mazumdar M, et al. Suramin and hydrocortisone: determining drug efficacy in androgen-independent prostate cancer. J Clin Oncol 1995; 13:2214-2222.
    • (1995) J Clin Oncol , vol.13 , pp. 2214-2222
    • Kelly, W.K.1    Scher, H.I.2    Mazumdar, M.3
  • 127
    • 0026740863 scopus 로고
    • Suramin: A novel growth factor antagonist with activity in hormone-refractory metastatic prostate cancer
    • Myers C, Cooper M, Stein C, et al. Suramin: a novel growth factor antagonist with activity in hormone-refractory metastatic prostate cancer. J Clin Oncol 1992; 10:881-889.
    • (1992) J Clin Oncol , vol.10 , pp. 881-889
    • Myers, C.1    Cooper, M.2    Stein, C.3
  • 128
    • 0029100139 scopus 로고
    • Suramin and prostate cancer: Where do we go from here?
    • Clark JW, Chabner BA. Suramin and prostate cancer: where do we go from here? J Clin Oncol 1995; 13:2155-2157.
    • (1995) J Clin Oncol , vol.13 , pp. 2155-2157
    • Clark, J.W.1    Chabner, B.A.2
  • 129
    • 0035214909 scopus 로고    scopus 로고
    • Thalidomide: A novel template for anticancer drugs
    • Stirling D. Thalidomide: a novel template for anticancer drugs. Semin Oncol, 2001; 28:602-606.
    • (2001) Semin Oncol , vol.28 , pp. 602-606
    • Stirling, D.1
  • 130
    • 0034783270 scopus 로고    scopus 로고
    • A randomized phase II trial of thalidomide, an angiogenesis inhibitor, in patients with androgen-independent prostate cancer
    • Figg WD, Dahut W, Duray P, et al. A randomized phase II trial of thalidomide, an angiogenesis inhibitor, in patients with androgen-independent prostate cancer. Clin Cancer Res 2001; 7:1888-1893.
    • (2001) Clin Cancer Res , vol.7 , pp. 1888-1893
    • Figg, W.D.1    Dahut, W.2    Duray, P.3
  • 131
    • 4344682179 scopus 로고    scopus 로고
    • Randomized phase II trial of docetaxel plus thalidomide in androgen-independent prostate cancer
    • Dahut WL, Gulley JL, Arlen PM, et al. Randomized phase II trial of docetaxel plus thalidomide in androgen-independent prostate cancer. J Clin Oncol 2004; 22:2532-2539.
    • (2004) J Clin Oncol , vol.22 , pp. 2532-2539
    • Dahut, W.L.1    Gulley, J.L.2    Arlen, P.M.3
  • 132
    • 0030856731 scopus 로고    scopus 로고
    • Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
    • Presta LG, Chen H, O'Connor SJ, et al. Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res 1997; 57:4593-4599.
    • (1997) Cancer Res , vol.57 , pp. 4593-4599
    • Presta, L.G.1    Chen, H.2    O'Connor, S.J.3
  • 133
    • 0035718890 scopus 로고    scopus 로고
    • A Phase II Trial of Humanized Anti-Vascular Endothelial Growth Factor Antibody for the Treatment of Androgen-Independent Prostate Cancer
    • Reese DM, Harris KA, Corry M, et al. A Phase II Trial of Humanized Anti-Vascular Endothelial Growth Factor Antibody for the Treatment of Androgen-Independent Prostate Cancer. Prostate J 2001; 3:65-70.
    • (2001) Prostate J , vol.3 , pp. 65-70
    • Reese, D.M.1    Harris, K.A.2    Corry, M.3
  • 134
    • 0036840759 scopus 로고    scopus 로고
    • Vascular endothelial growth factor immunoneutralization plus Paclitaxel markedly reduces tumor burden and ascites in athymic mouse model of ovarian cancer
    • Hu L, Hofmann J, Zaloudek C, et al. Vascular endothelial growth factor immunoneutralization plus Paclitaxel markedly reduces tumor burden and ascites in athymic mouse model of ovarian cancer. Am J Pathol 2002; 161:1917-1924.
    • (2002) Am J Pathol , vol.161 , pp. 1917-1924
    • Hu, L.1    Hofmann, J.2    Zaloudek, C.3
  • 135
    • 0036795180 scopus 로고    scopus 로고
    • Antibody to vascular endothelial growth factor slows growth of an androgen-independent xenograft model of prostate cancer
    • Fox WD, Higgins B, Maiese KM, et al. Antibody to vascular endothelial growth factor slows growth of an androgen-independent xenograft model of prostate cancer. Clin Cancer Res 2002; 8:3226-3231.
    • (2002) Clin Cancer Res , vol.8 , pp. 3226-3231
    • Fox, W.D.1    Higgins, B.2    Maiese, K.M.3
  • 136
    • 0346880557 scopus 로고    scopus 로고
    • The use of bevacizumab (B) with docetaxel (D) and estramustine (E) in hormone refractory prostate cancer (HRPC): Initial results of CALGB 90006
    • Abstract #1578
    • Picus J, Halabi S, Rini B, et al. The use of bevacizumab (B) with docetaxel (D) and estramustine (E) in hormone refractory prostate cancer (HRPC): Initial results of CALGB 90006. Proc Am Soc Clin Oncol 2003; 22:393 (Abstract #1578).
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 393
    • Picus, J.1    Halabi, S.2    Rini, B.3
  • 137
    • 0034660606 scopus 로고    scopus 로고
    • Endothelium-derived factors as paracrine mediators of prostate cancer progression
    • Pirtskhalaishvili G, Nelson JB. Endothelium-derived factors as paracrine mediators of prostate cancer progression. Prostate 2000; 44:77-87.
    • (2000) Prostate , vol.44 , pp. 77-87
    • Pirtskhalaishvili, G.1    Nelson, J.B.2
  • 138
    • 12444308202 scopus 로고    scopus 로고
    • Prostate cancer cells-osteoblast interaction shifts expression of growth/survival-related genes in prostate cancer and reduces expression of osteoprotegerin in osteoblasts
    • Fizazi K, Yang J, Peleg S, et al. Prostate cancer cells-osteoblast interaction shifts expression of growth/survival-related genes in prostate cancer and reduces expression of osteoprotegerin in osteoblasts. Clin Cancer Res 2003; 9:2587-2597.
    • (2003) Clin Cancer Res , vol.9 , pp. 2587-2597
    • Fizazi, K.1    Yang, J.2    Peleg, S.3
  • 139
    • 0037441843 scopus 로고    scopus 로고
    • Effect of endothelin-A receptor blockade with atrasentan on tumor progression in men with hormone-refractory prostate cancer: A randomized, phase II, placebo-controlled trial
    • Carducci MA, Padley RJ, Breul J, et al. Effect of endothelin-A receptor blockade with atrasentan on tumor progression in men with hormone-refractory prostate cancer: a randomized, phase II, placebo-controlled trial. J Clin Oncol 2003; 21:679-689.
    • (2003) J Clin Oncol , vol.21 , pp. 679-689
    • Carducci, M.A.1    Padley, R.J.2    Breul, J.3
  • 140
    • 0041464540 scopus 로고    scopus 로고
    • Phase I dose-escalation study of the safety and pharmacokinetics of atrasentan: An endothelin receptor antagonist for refractory prostate cancer
    • Zonnenberg BA, Groenewegen G, Janus TJ, et al. Phase I dose-escalation study of the safety and pharmacokinetics of atrasentan: an endothelin receptor antagonist for refractory prostate cancer. Clin Cancer Res 2003; 9:2965-2972.
    • (2003) Clin Cancer Res , vol.9 , pp. 2965-2972
    • Zonnenberg, B.A.1    Groenewegen, G.2    Janus, T.J.3
  • 141
    • 0037364732 scopus 로고    scopus 로고
    • A. Suppression of prostate cancer induced bone remodeling by the endothelin receptor A antagonist atrasentan
    • Nelson JB, Nabulsi AA, Vogelzang NJ, et al. A. Suppression of prostate cancer induced bone remodeling by the endothelin receptor A antagonist atrasentan. J Urol 2003; 169:1143-1149.
    • (2003) J Urol , vol.169 , pp. 1143-1149
    • Nelson, J.B.1    Nabulsi, A.A.2    Vogelzang, N.J.3
  • 142
    • 4043179333 scopus 로고    scopus 로고
    • Effects of atrasentan on disease progression and biological markers in men with metastatic hormone-refractory prostate cancer: Phase 3 study
    • Abstract #4508
    • Carducci MA, Nelson J, Saad F. Effects of atrasentan on disease progression and biological markers in men with metastatic hormone-refractory prostate cancer: Phase 3 study. Proc Am Soc Clin Oncol 2004; 23: (Abstract #4508).
    • (2004) Proc Am Soc Clin Oncol , vol.23
    • Carducci, M.A.1    Nelson, J.2    Saad, F.3
  • 143
    • 0001596022 scopus 로고    scopus 로고
    • Interim results of a phase III study of the matrix metalloprotease inhibitor prinomastat in patients having metastatic, hormone refractory prostate cancer
    • Abstract #692
    • Ahmann FR, Saad F, Mercier R, et al. Interim results of a phase III study of the matrix metalloprotease inhibitor prinomastat in patients having metastatic, hormone refractory prostate cancer. Proc Am Soc Clin Oncol 2001; 20:174a (Abstract #692).
    • (2001) Proc Am Soc Clin Oncol , vol.20
    • Ahmann, F.R.1    Saad, F.2    Mercier, R.3
  • 144
    • 11144235795 scopus 로고    scopus 로고
    • Angiogenesis inhibition in metastatic hormone refractory prostate cancer (HRPC): A randomized phase II trial of two doses of the matrix metalloproteinase inhibitor (MMPI) BMS-275291
    • Abstract #4647
    • Lara PN, Longmate J, Stadler W, et al. Angiogenesis inhibition in metastatic hormone refractory prostate cancer (HRPC): a randomized phase II trial of two doses of the matrix metalloproteinase inhibitor (MMPI) BMS-275291. Proc Am Soc Clin Oncol 2004; 23 (Abstract #4647).
    • (2004) Proc Am Soc Clin Oncol , vol.23
    • Lara, P.N.1    Longmate, J.2    Stadler, W.3
  • 145
    • 0037843596 scopus 로고    scopus 로고
    • Therapeutic targeting of the endothelin a receptor in human ovarian carcinoma
    • Rosano L, Spinella F, Salani D, et al. Therapeutic targeting of the endothelin a receptor in human ovarian carcinoma. Cancer Res 2003; 63:2447-2453.
    • (2003) Cancer Res , vol.63 , pp. 2447-2453
    • Rosano, L.1    Spinella, F.2    Salani, D.3
  • 146
    • 0036176126 scopus 로고    scopus 로고
    • Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: Requirement for Akt activation
    • Del Bufalo D, Di Castro V, Biroccio A, et al. Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: requirement for Akt activation. Mol Pharmacol 2002; 61:524-532.
    • (2002) Mol Pharmacol , vol.61 , pp. 524-532
    • Del Bufalo, D.1    Di Castro, V.2    Biroccio, A.3
  • 147
    • 0037112435 scopus 로고    scopus 로고
    • Growth inhibition of cervix carcinoma cells in vivo by endothelin A receptor blockade
    • Bagnato A, Cirilli A, Salani D, et al. Growth inhibition of cervix carcinoma cells in vivo by endothelin A receptor blockade. Cancer Res 2002; 62:6381-6384.
    • (2002) Cancer Res , vol.62 , pp. 6381-6384
    • Bagnato, A.1    Cirilli, A.2    Salani, D.3


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